Reducing the variability of antibiotic production in Streptomyces by cultivation in 24-square deepwell plates

Journal of Bioscience and Bioengineering

Volumn 109, Issue 3, 2010, Pages 230-234

  Siebenberg, Stefanie ^a   Bapat, Prashant M ^b   Lantz, Anna Eliasson ^b   Gust, Bertolt ^a   Heide, Lutz ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Antibiotic production; Deepwell plate; Nikkomycin; Novobiocin; Streptomyces

Indexed keywords

ANTIBIOTIC BIOSYNTHESIS; ANTIBIOTIC PRODUCTION; CULTURE MEDIUM; ERLENMEYER FLASKS; GROWTH PHASE; HIGH REPRODUCIBILITY; NIKKOMYCIN; NOVOBIOCIN; OVER-EXPRESSION; OXYGEN CARRIER; PRODUCTION MEDIUM; REPEATED CULTIVATION; REPRODUCIBLE PRODUCTION; STANDARD DEVIATION; STREPTOMYCETES;

BIOCHEMISTRY; BOTTLES; COST REDUCTION; ETHYLENE; OXYGEN;

ANTIBIOTICS;

AMINOCOUMARIN DERIVATIVE; COPOLYMER; ETHYLENE OXIDE; NIKKOMYCIN; NOVOBIOCIN; OXYGEN; PEPTONE; PROPYLENE OXIDE;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; CULTURE MEDIUM; DRUG MANUFACTURE; FOOD FREEZING; FUNGAL GENE; FUNGAL STRAIN; GENE OVEREXPRESSION; INOCULATION; MYCELIUM; NONHUMAN; NOVG GENE; NUCLEOTIDE SEQUENCE; SPECIES CULTIVATION; STREPTOMYCES; TEMPERATURE;

ANTI-BACTERIAL AGENTS; BIOREACTORS; CELL CULTURE TECHNIQUES; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; NOVOBIOCIN; STREPTOMYCES;

STREPTOMYCES; STREPTOMYCINEAE;

EID: 76049095346     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2009.08.479     Document Type: Article

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