Colloidal aggregation causes inhibition of G protein-coupled receptors

Journal of Medicinal Chemistry

Volumn 56, Issue 6, 2013, Pages 2406-2414

  Sassano, Maria F ^a   Doak, Allison K ^b   Roth, Bryan L ^a   Shoichet, Brian K ^b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOTRIMAZOLE; G PROTEIN COUPLED RECEPTOR; ITRACONAZOLE; LIGAND; POLYSORBATE 80; QUERCETIN; RECEPTOR BLOCKING AGENT; TETRA IODOPHENOLPHTHALEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL ASSAY; CENTRIFUGATION; COLLOID; COLLOIDAL AGGREGATION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; INVERSE AGONISM;

CELL LINE; CLOTRIMAZOLE; COLLOIDS; ITRACONAZOLE; LIGANDS; MODELS, MOLECULAR; PHENOLPHTHALEINS; PROTEIN CONFORMATION; QUERCETIN; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84875733971     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm301749y     Document Type: Article

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