-
1
-
-
0002493340
-
Brown adipose tissue in man
-
Trayhurn P, Nicholls DG, editors. Edward Arnold Ltd. London, UK
-
Lean MEJ, James PT. Brown adipose tissue in man. In: Trayhurn P, Nicholls DG, editors. Brown adipose tissue. Edward Arnold Ltd. London, UK; 1986. p. 339-65.
-
(1986)
Brown Adipose Tissue
, pp. 339-365
-
-
Lean, M.E.J.1
James, P.T.2
-
3
-
-
0025284845
-
Human uncoupling protein gene: Structure, comparison with rat gene, and assignment to the long arm of chromosome 4
-
Cassard AM, Bouillaud F, Mattei MG, Hentz E, Raimbault S, Thomas M, et al. Human uncoupling protein gene: structure, comparison with rat gene, and assignment to the long arm of chromosome 4. J Cell Biochem. 1990; 43: 255-64.
-
(1990)
J Cell Biochem.
, vol.43
, pp. 255-264
-
-
Cassard, A.M.1
Bouillaud, F.2
Mattei, M.G.3
Hentz, E.4
Raimbault, S.5
Thomas, M.6
-
4
-
-
0022007439
-
The characterization and energetic potential of brown adipose tissue in man
-
Cunningham S, Leslie P, Hopwood D, Illingworth P, Jung RT, Nicholls DG, et al. The characterization and energetic potential of brown adipose tissue in man. Clin Sci (Lond). 1985; 69: 343-8.
-
(1985)
Clin Sci (Lond)
, vol.69
, pp. 343-348
-
-
Cunningham, S.1
Leslie, P.2
Hopwood, D.3
Illingworth, P.4
Jung, R.T.5
Nicholls, D.G.6
-
5
-
-
0034289797
-
The human uncoupling protein-1 gene (UCP1): Present status and perspectives in obesity research
-
Del Mar Gonzalez-Barroso M, Ricquier D, Cassard-Doulcier AM. The human uncoupling protein-1 gene (UCP1): present status and perspectives in obesity research. Obes Rev. 2000; 1: 61-72.
-
(2000)
Obes Rev.
, vol.1
, pp. 61-72
-
-
Del Mar-Gonzalez-Barroso, M.1
Ricquier, D.2
Cassard-Doulcier, A.M.3
-
7
-
-
64349105205
-
Identification and importance of brown adipose tissue in adult humans
-
Cypess AM, Lehman S, Williams G, Tal I, Rodman D, Goldfine AB, et al. Identification and importance of brown adipose tissue in adult humans. N Engl J Med. 2009; 360: 1509-17.
-
(2009)
N Engl J Med.
, vol.360
, pp. 1509-1517
-
-
Cypess, A.M.1
Lehman, S.2
Williams, G.3
Tal, I.4
Rodman, D.5
Goldfine, A.B.6
-
8
-
-
64349123664
-
Functional brown adipose tissue in healthy adults
-
Virtanen KA, Lidell ME, Orava J, Heglind M, Westergren R, Niemi T, et al. Functional brown adipose tissue in healthy adults. N Engl J Med. 2009; 360: 1518-25.
-
(2009)
N Engl J Med.
, vol.360
, pp. 1518-1525
-
-
Virtanen, K.A.1
Lidell, M.E.2
Orava, J.3
Heglind, M.4
Westergren, R.5
Niemi, T.6
-
9
-
-
64349095231
-
Cold-activated brown adipose tissue in healthy men
-
van Marken Lichtenbelt WD, Vanhommerig JW, Smulders NM, Drossaerts JM, Kemerink GJ, Bouvy ND, et al. Cold-activated brown adipose tissue in healthy men. N Engl J Med. 2009; 360: 1500-8.
-
(2009)
N Engl J Med.
, vol.360
, pp. 1500-1508
-
-
Van Marken-Lichtenbelt, W.D.1
Vanhommerig, J.W.2
Smulders, N.M.3
Drossaerts, J.M.4
Kemerink, G.J.5
Bouvy, N.D.6
-
10
-
-
84880272552
-
Impact of UCP1 and β3AR gene polymorphisms on age-related changes in brown adipose tissue and adiposity in humans
-
Yoneshiro T, Ogawa T, Okamoto N, Matsushita M, Aita S, Kameya T, et al. Impact of UCP1 and β3AR gene polymorphisms on age-related changes in brown adipose tissue and adiposity in humans. Int J Obes (Lond). 2013; 37: 993-8.
-
(2013)
Int J Obes (Lond)
, vol.37
, pp. 993-998
-
-
Yoneshiro, T.1
Ogawa, T.2
Okamoto, N.3
Matsushita, M.4
Aita, S.5
Kameya, T.6
-
11
-
-
84868213635
-
Brown adipose tissue and the regulation of nonshivering thermogenesis
-
van Marken Lichtenbelt W. Brown adipose tissue and the regulation of nonshivering thermogenesis. Curr Opin Clin Nutr Metab Care. 2012; 15: 547-52.
-
(2012)
Curr Opin Clin Nutr Metab Care.
, vol.15
, pp. 547-552
-
-
Van Marken-Lichtenbelt, W.1
-
12
-
-
84897026162
-
Molecular imaging of brown adipose tissue in health and disease
-
Bauwens M, Wierts R, van Royen B, Bucerius J, Backes W, Mottaghy F, et al. Molecular imaging of brown adipose tissue in health and disease. Eur J Nucl Med Mol Imaging. 2014; 41: 776-91.
-
(2014)
Eur J Nucl Med Mol Imaging.
, vol.41
, pp. 776-791
-
-
Bauwens, M.1
Wierts, R.2
Van Royen, B.3
Bucerius, J.4
Backes, W.5
Mottaghy, F.6
-
13
-
-
0035366502
-
Emergence during development of the white-adipocyte cell phenotype is independent of the brown-adipocyte cell phenotype
-
Moulin K, Truel N, André M, Arnauld E, Nibbelink M, Cousin B, et al. Emergence during development of the white-adipocyte cell phenotype is independent of the brown-adipocyte cell phenotype. Biochem J. 2001; 356: 659-64.
-
(2001)
Biochem J.
, vol.356
, pp. 659-664
-
-
Moulin, K.1
Truel, N.2
André, M.3
Arnauld, E.4
Nibbelink, M.5
Cousin, B.6
-
14
-
-
34347353314
-
The generation of adipocytes by the neural crest
-
Billon N, Iannarelli P, Monteiro M C, G lavieux-Pardanaud C, Richardson WD, Kessaris N, et al. The generation of adipocytes by the neural crest. Development. 2007; 134: 2283-92.
-
(2007)
Development.
, vol.134
, pp. 2283-2292
-
-
Billon, N.1
Iannarelli, P.2
Monteiro, M.C.3
Lavieux-Pardanaud, C.G.4
Richardson, W.D.5
Kessaris, N.6
-
16
-
-
50049122271
-
PRDM16 controls a brown fat/skeletal muscle switch
-
Seale P, Bjork B, Yang W, Kajimura S, Chin S, Kuang S, et al. PRDM16 controls a brown fat/skeletal muscle switch. Nature. 2008; 454: 961-7.
-
(2008)
Nature
, vol.454
, pp. 961-967
-
-
Seale, P.1
Bjork, B.2
Yang, W.3
Kajimura, S.4
Chin, S.5
Kuang, S.6
-
17
-
-
78651094465
-
Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat
-
Schulz TJ, Huang TL, Tran TT, Zhang H, Townsend KL, Shadrach JL, et al. Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat. Proc Natl Acad Sci U S A. 2011; 108: 143-8.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 143-148
-
-
Schulz, T.J.1
Huang, T.L.2
Tran, T.T.3
Zhang, H.4
Townsend, K.L.5
Shadrach, J.L.6
-
18
-
-
84865792944
-
PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors
-
Sanchez-Gurmaches J, Hung CM, Sparks C, Tang Y, Li H, Guertin DA. PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors. Cell Metab. 2012; 16: 348-62.
-
(2012)
Cell Metab.
, vol.16
, pp. 348-362
-
-
Sanchez-Gurmaches, J.1
Hung, C.M.2
Sparks, C.3
Tang, Y.4
Li, H.5
Guertin, D.A.6
-
19
-
-
84859465056
-
In vivo identification of bipotential adipocyte progenitors recruited by b3-adrenoceptor activation and high-fat feeding
-
Lee YH, Petkova AP, Mottillo EP, Granneman JG. In vivo identification of bipotential adipocyte progenitors recruited by b3-adrenoceptor activation and high-fat feeding. Cell Metab. 2012; 15; 480-91.
-
(2012)
Cell Metab.
, vol.15
, pp. 480-491
-
-
Lee, Y.H.1
Petkova, A.P.2
Mottillo, E.P.3
Granneman, J.G.4
-
20
-
-
84874657953
-
Characterization of the adipocyte cellular lineage in vivo
-
Berry R, Rodeheffer MS. Characterization of the adipocyte cellular lineage in vivo. Nat Cell Biol. 2013; 15: 302-8.
-
(2013)
Nat Cell Biol.
, vol.15
, pp. 302-308
-
-
Berry, R.1
Rodeheffer, M.S.2
-
21
-
-
84873518501
-
Adaptive thermogenesis in adipocytes: Is beige the new brown?
-
Wu J, Cohen P, Spiegelman BM. Adaptive thermogenesis in adipocytes: is beige the new brown? Genes Dev. 2013; 27: 234-25.
-
(2013)
Genes Dev.
, vol.27
, pp. 234-325
-
-
Wu, J.1
Cohen, P.2
Spiegelman, B.M.3
-
22
-
-
84875367849
-
Brown-fat paucity due to impaired-BMP signalling induces compensatory browning of white fat
-
Schulz TJ, Huang P, Huang TL, Xue R, McDougall LE, Townsend KL, et al. Brown-fat paucity due to impaired-BMP signalling induces compensatory browning of white fat. Nature. 2013; 495, 379-83.
-
(2013)
Nature
, vol.495
, pp. 379-383
-
-
Schulz, T.J.1
Huang, P.2
Huang, T.L.3
Xue, R.4
McDougall, L.E.5
Townsend, K.L.6
-
23
-
-
77950226740
-
Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes
-
Petrovic N, Walden T B, Shabalina I G, Timmons J A, Cannon B, Nedergaard J. Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes. J Biol Chem. 2010; 285: 7153-64.
-
(2010)
J Biol Chem.
, vol.285
, pp. 7153-7164
-
-
Petrovic, N.1
Walden, T.B.2
Shabalina, I.G.3
Timmons, J.A.4
Cannon, B.5
Nedergaard, J.6
-
24
-
-
77953010087
-
Medicine. Beige can be slimming
-
Ishibashi J, Seale P. Medicine. Beige can be slimming. Science. 2010; 328: 1113-14.
-
(2010)
Science
, vol.328
, pp. 1113-1114
-
-
Ishibashi, J.1
Seale, P.2
-
25
-
-
84864287504
-
Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human
-
Wu J, Boström P, Sparks LM, Ye L, Choi JH, Giang AH, et al. Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell. 2012; 150: 366-76.
-
(2012)
Cell
, vol.150
, pp. 366-376
-
-
Wu, J.1
Boström, P.2
Sparks, L.M.3
Ye, L.4
Choi, J.H.5
Giang, A.H.6
-
26
-
-
33845977987
-
Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fat
-
Xue B, Rim JS, Hogan JC, Coulter AA, Koza RA, Kozak LP. Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fat. J Lipid Res. 2007; 48: 41-51.
-
(2007)
J Lipid Res.
, vol.48
, pp. 41-51
-
-
Xue, B.1
Rim, J.S.2
Hogan, J.C.3
Coulter, A.A.4
Koza, R.A.5
Kozak, L.P.6
-
27
-
-
83455198397
-
Recruited vs. Nonrecruited molecular signatures of brown, "brite," and white adipose tissues
-
Waldén TB, Hansen IR, Timmons JA, Cannon B, Nedergaard J. Recruited vs. nonrecruited molecular signatures of brown, "brite," and white adipose tissues. Am J Physiol Endocrinol Metab. 2012; 302: E19-31.
-
(2012)
Am J Physiol Endocrinol Metab.
, vol.302
, pp. E19-31
-
-
Waldén, T.B.1
Hansen, I.R.2
Timmons, J.A.3
Cannon, B.4
Nedergaard, J.5
-
28
-
-
84868138313
-
The adipose organ: Whitebrown adipocyte plasticity and metabolic inflammation
-
Smorlesi A, Frontini A, Giordano A, Cinti S. The adipose organ: whitebrown adipocyte plasticity and metabolic inflammation. Obes Rev. 2012; 13(Suppl 2): 83-96.
-
(2012)
Obes Rev.
, vol.13
, pp. 83-96
-
-
Smorlesi, A.1
Frontini, A.2
Giordano, A.3
Cinti, S.4
-
29
-
-
84887431711
-
Brown and beige fat: Development, function and therapeutic potential
-
Harms M, Seale P. Brown and beige fat: development, function and therapeutic potential. Nat Med. 2013; 19: 1252-63.
-
(2013)
Nat Med.
, vol.19
, pp. 1252-1263
-
-
Harms, M.1
Seale, P.2
-
30
-
-
0033825933
-
Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes
-
Himms-Hagen J, Melnyk A, Zingaretti MC, Ceresi E, Barbatelli G, Cinti S. Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes. Am J Physiol Cell Physiol. 2000; 279: C670-81.
-
(2000)
Am J Physiol Cell Physiol.
, vol.279
, pp. C670-C681
-
-
Himms-Hagen, J.1
Melnyk, A.2
Zingaretti, M.C.3
Ceresi, E.4
Barbatelli, G.5
Cinti, S.6
-
31
-
-
77952623888
-
The emergence of cold induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation
-
Barbatelli G, Murano I, Madsen L, Hao Q, Jimenez M, Kristiansen K, et al. The emergence of cold induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation. Am J Physiol Endocrinol Metab. 2010; 298: E1244-53.
-
(2010)
Am J Physiol Endocrinol Metab.
, vol.298
, pp. E1244-E1253
-
-
Barbatelli, G.1
Murano, I.2
Madsen, L.3
Hao, Q.4
Jimenez, M.5
Kristiansen, K.6
-
32
-
-
84859410604
-
The adipose organ of obesity-prone C57BL/6J mice is composed of mixed white and brown adipocytes
-
Vitali A, Murano I, Zingaretti M C, Frontini A, Ricquier D, Cinti S. The adipose organ of obesity-prone C57BL/6J mice is composed of mixed white and brown adipocytes. J Lipid Res. 2012; 53: 619-29.
-
(2012)
J Lipid Res.
, vol.53
, pp. 619-629
-
-
Vitali, A.1
Murano, I.2
Zingaretti, M.C.3
Frontini, A.4
Ricquier, D.5
Cinti, S.6
-
34
-
-
84887502374
-
Tracking adipogenesis during white adipose tissue development, expansion and regeneration
-
Wang QA, Tao C, Gupta RK, Scherer PE. Tracking adipogenesis during white adipose tissue development, expansion and regeneration. Nat Med. 2013; 19: 1338-44.
-
(2013)
Nat Med.
, vol.19
, pp. 1338-1344
-
-
Wang, Q.A.1
Tao, C.2
Gupta, R.K.3
Scherer, P.E.4
-
35
-
-
84900325394
-
A smooth muscle-like origin for beige adipocytes
-
Long JZ, Svensson KJ, Tsai L, Zeng X, Roh HC, Kong X, et al. A smooth muscle-like origin for beige adipocytes. Cell Metab. 2014; 19: 810-20.
-
(2014)
Cell Metab.
, vol.19
, pp. 810-820
-
-
Long, J.Z.1
Svensson, K.J.2
Tsai, L.3
Zeng, X.4
Roh, H.C.5
Kong, X.6
-
36
-
-
84890234667
-
UCP1 in brite/beige adipose tissue mitochondria is functionally thermogenic
-
Shabalina IG, Petrovic N, de Jong JM, Kalinovich AV, Cannon B, Nedergaard J. UCP1 in brite/beige adipose tissue mitochondria is functionally thermogenic. Cell Rep. 2013; 5: 1196-203.
-
(2013)
Cell Rep.
, vol.5
, pp. 1196-1203
-
-
Shabalina, I.G.1
Petrovic, N.2
De Jong, J.M.3
Kalinovich, A.V.4
Cannon, B.5
Nedergaard, J.6
-
37
-
-
0032528169
-
Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity
-
Guerra C, Koza RA, Yamashita H, Walsh K, Kozak LP. Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity. J Clin Invest. 1998; 102: 412-20.
-
(1998)
J Clin Invest.
, vol.102
, pp. 412-420
-
-
Guerra, C.1
Koza, R.A.2
Yamashita, H.3
Walsh, K.4
Kozak, L.P.5
-
39
-
-
33748942837
-
Transcriptional control of adipocyte formation
-
Farmer SR. Transcriptional control of adipocyte formation. Cell Metab. 2006; 4: 263-73.
-
(2006)
Cell Metab.
, vol.4
, pp. 263-273
-
-
Farmer, S.R.1
-
40
-
-
0033213637
-
PPARγ is required for placental, cardiac, and adipose tissue development
-
Barak Y, Nelson MC, Ong ES, Jones YZ, Ruiz-Lozano P, Chien KR, et al. PPARγ is required for placental, cardiac, and adipose tissue development. Mol Cell. 1999; 4: 585-95.
-
(1999)
Mol Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.1
Nelson, M.C.2
Ong, E.S.3
Jones, Y.Z.4
Ruiz-Lozano, P.5
Chien, K.R.6
-
41
-
-
0033213631
-
PPARgamma is required for the differentiation of adipose tissue in vivo and in vitro
-
Rosen ED, Sarraf P, Troy AE, Bradwin G, Moore K, Milstone DS, et al. PPARgamma is required for the differentiation of adipose tissue in vivo and in vitro. Mol Cell. 1999; 4: 611-17.
-
(1999)
Mol Cell
, vol.4
, pp. 611-617
-
-
Rosen, E.D.1
Sarraf, P.2
Troy, A.E.3
Bradwin, G.4
Moore, K.5
Milstone, D.S.6
-
42
-
-
0033083803
-
Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity
-
Wu Z, Rosen ED, Brun R, Hauser S, Adelmant G, Troy AE, et al. Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity. Mol Cell. 1999; 3: 151-8.
-
(1999)
Mol Cell
, vol.3
, pp. 151-158
-
-
Wu, Z.1
Rosen, E.D.2
Brun, R.3
Hauser, S.4
Adelmant, G.5
Troy, A.E.6
-
43
-
-
0035940360
-
C/EBPalpha is required for differentiation of white, but not brown, adipose tissue
-
Linhart HG, Ishimura-Oka K, De Mayo F, Kibe T, Repka D, Poindexter B, et al. C/EBPalpha is required for differentiation of white, but not brown, adipose tissue. Proc Natl Acad Sci U S A. 2001; 98: 12532-7.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 12532-12537
-
-
Linhart, H.G.1
Ishimura-Oka, K.2
De Mayo, F.3
Kibe, T.4
Repka, D.5
Poindexter, B.6
-
44
-
-
0037077240
-
Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein alpha
-
Carmona MC, Iglesias R, Obregón MJ, Darlington GJ, Villarroya F, Giralt M. Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein alpha. J Biol Chem. 2002; 277: 21489-98.
-
(2002)
J Biol Chem.
, vol.277
, pp. 21489-21498
-
-
Carmona, M.C.1
Iglesias, R.2
Obregón, M.J.3
Darlington, G.J.4
Villarroya, F.5
Giralt, M.6
-
45
-
-
69349088117
-
Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex
-
Kajimura S, Seale P, Kubota K, Lunsford E, Frangioni JV, Gygi SP, et al. Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex. Nature. 2009; 460: 1154-8.
-
(2009)
Nature
, vol.460
, pp. 1154-1158
-
-
Kajimura, S.1
Seale, P.2
Kubota, K.3
Lunsford, E.4
Frangioni, J.V.5
Gygi, S.P.6
-
46
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell. 1998; 92: 829-39.
-
(1998)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
47
-
-
0035847001
-
Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell
-
Barbera MJ, Schluter A, Pedraza N, Iglesias R, Villarroya F, Giralt M. Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell. J Biol Chem. 2001; 276: 1486-93.
-
(2001)
J Biol Chem.
, vol.276
, pp. 1486-1493
-
-
Barbera, M.J.1
Schluter, A.2
Pedraza, N.3
Iglesias, R.4
Villarroya, F.5
Giralt, M.6
-
48
-
-
33646124709
-
Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation
-
Uldry M, Yang W, St-Pierre J, Lin J, Seale P, Spiegelman BM. Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation. Cell Metab. 2006; 3: 333-41.
-
(2006)
Cell Metab.
, vol.3
, pp. 333-341
-
-
Uldry, M.1
Yang, W.2
St-Pierre, J.3
Lin, J.4
Seale, P.5
Spiegelman, B.M.6
-
49
-
-
34347326271
-
Transcriptional control of brown fat determination by PRDM16
-
Seale P, Kajimura S, Yang W, Chin S, Rohas LM, Uldry M, et al. Transcriptional control of brown fat determination by PRDM16. Cell Metab. 2007; 6: 38-54.
-
(2007)
Cell Metab.
, vol.6
, pp. 38-54
-
-
Seale, P.1
Kajimura, S.2
Yang, W.3
Chin, S.4
Rohas, L.M.5
Uldry, M.6
-
50
-
-
83355163350
-
Peroxisome proliferator activated receptor-alpha (PPARα) induces PPARγ - Coactivator 1α (PGC-1α) gene expression and contributes to thermogenic activation of brown fat: Involvement of PRDM16
-
Hondares E, Rosell M, Díaz-Delfín J, Olmos Y, Monsalve M, Iglesias R, et al. Peroxisome proliferator activated receptor-alpha (PPARα) induces PPARγ - coactivator 1α (PGC-1α) gene expression and contributes to thermogenic activation of brown fat: involvement of PRDM16. J Biol Chem. 2011; 286: 43112-22.
-
(2011)
J Biol Chem.
, vol.286
, pp. 43112-43122
-
-
Hondares, E.1
Rosell, M.2
Díaz-Delfín, J.3
Olmos, Y.4
Monsalve, M.5
Iglesias, R.6
-
51
-
-
84883149316
-
MicroRNA networks regulate development of brown adipocytes
-
Trajkovski M, Lodish H. MicroRNA networks regulate development of brown adipocytes. Trends Endocrinol Metab. 2013; 24: 442-50.
-
(2013)
Trends Endocrinol Metab.
, vol.24
, pp. 442-450
-
-
Trajkovski, M.1
Lodish, H.2
-
52
-
-
84875358826
-
Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARgamma specifies lipid storage versus thermogenic gene programs
-
Villanueva CJ, Vergnes L, Wang J, Drew BG, Hong C, Tu Y, et al. Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARgamma specifies lipid storage versus thermogenic gene programs. Cell Metab. 2013; 17: 423-35.
-
(2013)
Cell Metab.
, vol.17
, pp. 423-435
-
-
Villanueva, C.J.1
Vergnes, L.2
Wang, J.3
Drew, B.G.4
Hong, C.5
Tu, Y.6
-
53
-
-
84892702771
-
Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch
-
Cohen P, Levy JD, Zhang Y, Frontini A, Kolodin DP, Svensson KJ, et al. Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch. Cell. 2014; 156: 304-16.
-
(2014)
Cell
, vol.156
, pp. 304-316
-
-
Cohen, P.1
Levy, J.D.2
Zhang, Y.3
Frontini, A.4
Kolodin, D.P.5
Svensson, K.J.6
-
54
-
-
84897525104
-
Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice
-
Harms MJ, Ishibashi J, Wang W, Lim HW, Goyama S, Sato T, et al. Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice. Cell Metab. 2014; 19: 593-604.
-
(2014)
Cell Metab.
, vol.19
, pp. 593-604
-
-
Harms, M.J.1
Ishibashi, J.2
Wang, W.3
Lim, H.W.4
Goyama, S.5
Sato, T.6
-
56
-
-
84869233588
-
Human BAT possesses molecular signatures that resemble beige/brite cells
-
Sharp L Z, Shinoda K, Ohno H, Scheel D W, Tomoda E, Ruiz L, et al. Human BAT possesses molecular signatures that resemble beige/brite cells. PLoS One. 2012; 7: e49452
-
(2012)
PLoS One
, vol.7
, pp. e49452
-
-
Sharp, L.Z.1
Shinoda, K.2
Ohno, H.3
Scheel, D.W.4
Tomoda, E.5
Ruiz, L.6
-
57
-
-
84903521572
-
Expression of adipocyte biomarkers in a primary cell culture model reflects pre-weaning adipobiology
-
Chu DT, Malinowska E, Gawronska-Kozak B, Kozak LP. Expression of adipocyte biomarkers in a primary cell culture model reflects pre-weaning adipobiology. J Biol Chem. 2014; 289: 18478-88.
-
(2014)
J Biol Chem.
, vol.289
, pp. 18478-18488
-
-
Chu, D.T.1
Malinowska, E.2
Gawronska-Kozak, B.3
Kozak, L.P.4
-
58
-
-
84904636950
-
The origin and definition of brite versus white and classical brown adipocytes
-
Rosenwald M, Wolfrum C. The origin and definition of brite versus white and classical brown adipocytes. Adipocyte. 2014; 3: 4-9.
-
(2014)
Adipocyte.
, vol.3
, pp. 4-9
-
-
Rosenwald, M.1
Wolfrum, C.2
-
59
-
-
35348874911
-
Developmental origin of fat: Tracking obesity to its source
-
Gesta S, Tseng YH, Kahn CR. Developmental origin of fat: tracking obesity to its source. Cell. 2007; 131: 242-56.
-
(2007)
Cell
, vol.131
, pp. 242-256
-
-
Gesta, S.1
Tseng, Y.H.2
Kahn, C.R.3
-
60
-
-
84877580638
-
Mechanisms and metabolic implications of regional differences among fat depots
-
Tchkonia T, Thomou T, Zhu Y, Karagiannides I, Pothoulakis C, Jensen MD, et al. Mechanisms and metabolic implications of regional differences among fat depots. Cell Metab. 2013; 17: 644-56.
-
(2013)
Cell Metab.
, vol.17
, pp. 644-656
-
-
Tchkonia, T.1
Thomou, T.2
Zhu, Y.3
Karagiannides, I.4
Pothoulakis, C.5
Jensen, M.D.6
-
61
-
-
84892727198
-
What we talk about when we talk about fat
-
Rosen ED, Spiegelman BM. What we talk about when we talk about fat. Cell. 2014; 156: 20-44.
-
(2014)
Cell
, vol.156
, pp. 20-44
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
62
-
-
80054760368
-
Fiber types in mammalian skeletal muscles
-
Schiaffino S, Reggiani C. Fiber types in mammalian skeletal muscles. Physiol Rev. 2011; 91: 1447-531.
-
(2011)
Physiol Rev.
, vol.91
, pp. 1447-1531
-
-
Schiaffino, S.1
Reggiani, C.2
-
63
-
-
0027051199
-
Occurrence of brown adipocytes in rat white adipose tissue: Molecular and morphological characterization
-
Cousin B, Cinti S, Morroni M, Raimbault S, Ricquier D, Pénicaud L, et al. Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization. J Cell Sci. 1992; 103: 931-42.
-
(1992)
J Cell Sci.
, vol.103
, pp. 931-942
-
-
Cousin, B.1
Cinti, S.2
Morroni, M.3
Raimbault, S.4
Ricquier, D.5
Pénicaud, L.6
-
64
-
-
79955755051
-
Exercise ameliorates high-fat diet-induced metabolic and vascular dysfunction, and increases adipocyte progenitor cell population in brown adipose tissue
-
Xu X, Ying Z, Cai M, Xu Z, Li Y, Jiang SY, et al. Exercise ameliorates high-fat diet-induced metabolic and vascular dysfunction, and increases adipocyte progenitor cell population in brown adipose tissue. Am J Physiol Regul Integr Comp Physiol. 2011; 300: R1115-25.
-
(2011)
Am J Physiol Regul Integr Comp Physiol.
, vol.300
, pp. R1115-R1125
-
-
Xu, X.1
Ying, Z.2
Cai, M.3
Xu, Z.4
Li, Y.5
Jiang, S.Y.6
-
65
-
-
84862776702
-
A PGC1-Á-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
-
Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, et al. A PGC1-á-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 2012; 481: 463-8.
-
(2012)
Nature
, vol.481
, pp. 463-468
-
-
Boström, P.1
Wu, J.2
Jedrychowski, M.P.3
Korde, A.4
Ye, L.5
Lo, J.C.6
-
66
-
-
77249099832
-
Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat
-
Hondares E, Rosell M, Gonzalez FJ, Giralt M, Iglesias R, Villarroya F. Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat. Cell Metab. 2010; 11: 206-12.
-
(2010)
Cell Metab.
, vol.11
, pp. 206-212
-
-
Hondares, E.1
Rosell, M.2
Gonzalez, F.J.3
Giralt, M.4
Iglesias, R.5
Villarroya, F.6
-
67
-
-
84863012022
-
FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis
-
Fisher FM, Kleiner S, Douris N, Fox EC, Mepani RJ, Verdeguer F, et al. FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis. Genes Dev. 2012; 26: 271-81.
-
(2012)
Genes Dev.
, vol.26
, pp. 271-281
-
-
Fisher, F.M.1
Kleiner, S.2
Douris, N.3
Fox, E.C.4
Mepani, R.J.5
Verdeguer, F.6
-
68
-
-
84862622024
-
FGF21: The center of a transcriptional nexus in metabolic regulation
-
Adams AC, Kharitonenkov A. FGF21: the center of a transcriptional nexus in metabolic regulation. Curr Diabetes Rev. 2012; 8: 285-93.
-
(2012)
Curr Diabetes Rev.
, vol.8
, pp. 285-293
-
-
Adams, A.C.1
Kharitonenkov, A.2
-
69
-
-
79953886306
-
Thermogenic activation induces FGF21 expression and release in brown adipose tissue
-
Hondares E, Iglesias R, Giralt A, Gonzalez FJ, Giralt M, Mampel T, et al. Thermogenic activation induces FGF21 expression and release in brown adipose tissue. J Biol Chem. 2011; 286: 12983-90.
-
(2011)
J Biol Chem.
, vol.286
, pp. 12983-12990
-
-
Hondares, E.1
Iglesias, R.2
Giralt, A.3
Gonzalez, F.J.4
Giralt, M.5
Mampel, T.6
-
70
-
-
84877585823
-
Beyond the sympathetic tone: The new brown fat activators
-
Villarroya F, Vidal-Puig A. Beyond the sympathetic tone: the new brown fat activators. Cell Metab. 2013; 17: 638-43.
-
(2013)
Cell Metab.
, vol.17
, pp. 638-643
-
-
Villarroya, F.1
Vidal-Puig, A.2
-
71
-
-
84863229962
-
Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes
-
Bordicchia M, Liu D, Amri EZ, Ailhaud G, Dessì-Fulgheri P, Zhang C, et al. Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes. J Clin Invest. 2012; 122: 1022-36.
-
(2012)
J Clin Invest.
, vol.122
, pp. 1022-1036
-
-
Bordicchia, M.1
Liu, D.2
Amri, E.Z.3
Ailhaud, G.4
Dessì-Fulgheri, P.5
Zhang, C.6
-
72
-
-
1642378141
-
Retinoids and retinoid receptors in the control of energy balance: Novel pharmacological strategies in obesity and diabetes
-
Villarroya F, Iglesias R, Giralt M. Retinoids and retinoid receptors in the control of energy balance: novel pharmacological strategies in obesity and diabetes. Curr Med Chem. 2004; 11: 795-805.
-
(2004)
Curr Med Chem.
, vol.11
, pp. 795-805
-
-
Villarroya, F.1
Iglesias, R.2
Giralt, M.3
-
73
-
-
84891840977
-
β-aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors
-
Roberts LD, Boström P, O'Sullivan JF, Schinzel RT, Lewis GD, Dejam A, et al. β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors. Cell Metab. 2014; 19: 96-108.
-
(2014)
Cell Metab.
, vol.19
, pp. 96-108
-
-
Roberts, L.D.1
Boström, P.2
O'Sullivan, J.F.3
Schinzel, R.T.4
Lewis, G.D.5
Dejam, A.6
-
74
-
-
84907485620
-
Browning of white adipose cells by intermediate metabolites: An adaptive mechanism to alleviate redox pressure
-
May 1. [Epub ahead of print]
-
Carrière A, Jeanson Y, Berger-Müller S, AndréM, Chenouard V, Arnaud E, et al. Browning of white adipose cells by intermediate metabolites: an adaptive mechanism to alleviate redox pressure. Diabetes. 2014 May 1. [Epub ahead of print].
-
(2014)
Diabetes
-
-
Carrière, A.1
Jeanson, Y.2
Berger-Müller, S.3
André, M.4
Chenouard, V.5
Arnaud, E.6
-
75
-
-
70349334680
-
The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue
-
Zingaretti MC, Crosta F, Vitali A, Guerrieri M, Frontini A, Cannon B, et al. The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue. FASEB J. 2009; 23: 3113-20.
-
(2009)
FASEB J.
, vol.23
, pp. 3113-3120
-
-
Zingaretti, M.C.1
Crosta, F.2
Vitali, A.3
Guerrieri, M.4
Frontini, A.5
Cannon, B.6
-
76
-
-
84877340732
-
Evidence for two types of brown adipose tissue in humans
-
Lidell ME, Betz MJ, Dahlqvist Leinhard O, Heglind M, Elander L, Slawik M, et al. Evidence for two types of brown adipose tissue in humans. Nat Med. 2013; 19: 631-4.
-
(2013)
Nat Med.
, vol.19
, pp. 631-634
-
-
Lidell, M.E.1
Betz, M.J.2
Dahlqvist-Leinhard, O.3
Heglind, M.4
Elander, L.5
Slawik, M.6
-
77
-
-
84894058844
-
Fibroblast growth factor-21 is expressed in neonatal and pheochromocytoma-induced adult human brown adipose tissue
-
Hondares E, Gallego-Escuredo JM, Flachs P, Frontini A, Cereijo R, Goday A, et al. Fibroblast growth factor-21 is expressed in neonatal and pheochromocytoma-induced adult human brown adipose tissue. Metabolism. 2014; 63: 312-17.
-
(2014)
Metabolism.
, vol.63
, pp. 312-317
-
-
Hondares, E.1
Gallego-Escuredo, J.M.2
Flachs, P.3
Frontini, A.4
Cereijo, R.5
Goday, A.6
-
78
-
-
84877331455
-
Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat
-
Cypess AM, White AP, Vernochet C, Schulz TJ, Xue R, Sass CA, et al. Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat. Nat Med. 2013; 19: 635-9.
-
(2013)
Nat Med.
, vol.19
, pp. 635-639
-
-
Cypess, A.M.1
White, A.P.2
Vernochet, C.3
Schulz, T.J.4
Xue, R.5
Sass, C.A.6
-
79
-
-
84877263632
-
A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humans
-
Jespersen NZ, Larsen TJ, Peijs L, Daugaard S, Homøe P, Loft A, et al. A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humans. Cell Metab. 2013; 17: 798-805.
-
(2013)
Cell Metab.
, vol.17
, pp. 798-805
-
-
Jespersen, N.Z.1
Larsen, T.J.2
Peijs, L.3
Daugaard, S.4
Homøe, P.5
Loft, A.6
-
80
-
-
84920702690
-
Opposite alterations in FGF21 and FGF19 levels and disturbed expression of the receptor machinery for endocrine FGFs in obese patients
-
May 12. [Epub ahead of print]
-
Gallego-Escuredo JM, Gómez-Ambrosi J, Catalan V, Domingo P, Giralt M, Frühbeck G, et al. Opposite alterations in FGF21 and FGF19 levels and disturbed expression of the receptor machinery for endocrine FGFs in obese patients. Int J Obes (Lond). 2014 May 12. [Epub ahead of print].
-
(2014)
Int J Obes (Lond)
-
-
Gallego-Escuredo, J.M.1
Gómez-Ambrosi, J.2
Catalan, V.3
Domingo, P.4
Giralt, M.5
Frühbeck, G.6
-
81
-
-
73049135711
-
On the degeneration of brown fatty tissue in pheochromocytoma
-
Feyrter F. On the degeneration of brown fatty tissue in pheochromocytoma. Wien Med Wochenschr. 1961; 111: 648-9.
-
(1961)
Wien Med Wochenschr.
, vol.111
, pp. 648-649
-
-
Feyrter, F.1
-
82
-
-
0020466632
-
Ultrastructural and biochemical characterization of human brown adipose tissue in pheochromocytoma
-
Ricquier D, Nechad M, Mory G. Ultrastructural and biochemical characterization of human brown adipose tissue in pheochromocytoma. J Clin Endocrinol Metab. 1982; 54: 803-7.
-
(1982)
J Clin Endocrinol Metab.
, vol.54
, pp. 803-807
-
-
Ricquier, D.1
Nechad, M.2
Mory, G.3
-
84
-
-
0023918699
-
Detection of brown adipose tissue uncoupling protein mRNA in adult patients by a human genomic probe
-
Bouillaud F, Villarroya F, Hentz E, Raimbault S, Cassard AM, Ricquier D. Detection of brown adipose tissue uncoupling protein mRNA in adult patients by a human genomic probe. Clin Sci (Lond). 1988; 75: 21-7.
-
(1988)
Clin Sci (Lond)
, vol.75
, pp. 21-27
-
-
Bouillaud, F.1
Villarroya, F.2
Hentz, E.3
Raimbault, S.4
Cassard, A.M.5
Ricquier, D.6
-
85
-
-
84875858745
-
White-to-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma
-
Frontini A, Vitali A, Perugini J, Murano I, Romiti C, Ricquier D, et al. White-to-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma. Biochim Biophys Acta. 2013; 1831: 950-9.
-
(2013)
Biochim Biophys Acta.
, vol.1831
, pp. 950-959
-
-
Frontini, A.1
Vitali, A.2
Perugini, J.3
Murano, I.4
Romiti, C.5
Ricquier, D.6
-
86
-
-
34447315786
-
Brown fat imaging with (18)F-6-fluorodopamine PET/CT, (18)F-FDG PET/CT, and (123)I-MIBG SPECT: A study of patients being evaluated for pheochromocytoma
-
Hadi M, Chen CC, Whatley M, Pacak K, Carrasquillo JA. Brown fat imaging with (18)F-6-fluorodopamine PET/CT, (18)F-FDG PET/CT, and (123)I-MIBG SPECT: a study of patients being evaluated for pheochromocytoma. J Nucl Med. 2007; 48: 1077-83.
-
(2007)
J Nucl Med.
, vol.48
, pp. 1077-1083
-
-
Hadi, M.1
Chen, C.C.2
Whatley, M.3
Pacak, K.4
Carrasquillo, J.A.5
-
87
-
-
79959305513
-
Brown adipose tissue in humans is activated by elevated plasma catecholamines levels and is inversely related to central obesity
-
Wang Q, Zhang M, Ning G, Gu W, Su T, Xu M, et al. Brown adipose tissue in humans is activated by elevated plasma catecholamines levels and is inversely related to central obesity. PLoS One. 2011; 6: e21006.
-
(2011)
PLoS One
, vol.6
, pp. e21006
-
-
Wang, Q.1
Zhang, M.2
Ning, G.3
Gu, W.4
Su, T.5
Xu, M.6
-
88
-
-
84859650824
-
Intense FDG activity in the brown adipose tissue in omental and mesenteric regions in a patient with malignant pheochromocytoma
-
Cheng W, Zhu Z, Jin X, Chen L, Zhuang H, Li F. Intense FDG activity in the brown adipose tissue in omental and mesenteric regions in a patient with malignant pheochromocytoma. Clin Nucl Med. 2012; 37: 514-15.
-
(2012)
Clin Nucl Med.
, vol.37
, pp. 514-515
-
-
Cheng, W.1
Zhu, Z.2
Jin, X.3
Chen, L.4
Zhuang, H.5
Li, F.6
-
89
-
-
85028105813
-
Hypermetabolic mesenteric brown adipose tissue on dual-time point FDG PET/CT in a patient with benign retroperitoneal pheochromocytoma
-
Dong A, Wang Y, Lu J, Zuo C. Hypermetabolic mesenteric brown adipose tissue on dual-time point FDG PET/CT in a patient with benign retroperitoneal pheochromocytoma. Clin Nucl Med. 2014; 39: e229-32.
-
(2014)
Clin Nucl Med.
, vol.39
, pp. e229-e232
-
-
Dong, A.1
Wang, Y.2
Lu, J.3
Zuo, C.4
-
90
-
-
0030717887
-
Uncoupling protein gene: Quantification of expression levels in adipose tissues of obese and non-obese humans
-
Oberkofler H, Dallinger G, Liu YM, Hell E, Krempler F, Patsch W. Uncoupling protein gene: quantification of expression levels in adipose tissues of obese and non-obese humans. J Lipid Res. 1997; 38: 2125-33.
-
(1997)
J Lipid Res.
, vol.38
, pp. 2125-2133
-
-
Oberkofler, H.1
Dallinger, G.2
Liu, Y.M.3
Hell, E.4
Krempler, F.5
Patsch, W.6
-
91
-
-
84860850964
-
BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions
-
Whittle AJ, Carobbio S, Martins L, Slawik M, Hondares E, Vázquez MJ, et al. BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions. Cell. 2012; 149: 871-85.
-
(2012)
Cell
, vol.149
, pp. 871-885
-
-
Whittle, A.J.1
Carobbio, S.2
Martins, L.3
Slawik, M.4
Hondares, E.5
Vázquez, M.J.6
-
93
-
-
67650242165
-
High incidence of metabolically active brown adipose tissue in healthy adult humans: Effects of cold exposure and adiposity
-
Saito M, Okamatsu-Ogura Y, Matsushita M, Watanabe K, Yoneshiro T, Nio-Kobayashi J, et al. High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity. Diabetes. 2009; 58: 1526-31.
-
(2009)
Diabetes
, vol.58
, pp. 1526-1531
-
-
Saito, M.1
Okamatsu-Ogura, Y.2
Matsushita, M.3
Watanabe, K.4
Yoneshiro, T.5
Nio-Kobayashi, J.6
-
94
-
-
34250334737
-
Reduction of FDG uptake in brown adipose tissue in clinical patients by a single dose of propranolol
-
Söderlund V, Larsson SA, Jacobsson H. Reduction of FDG uptake in brown adipose tissue in clinical patients by a single dose of propranolol. Eur J Nucl Med Mol Imaging. 2007; 34: 1018-22.
-
(2007)
Eur J Nucl Med Mol Imaging.
, vol.34
, pp. 1018-1022
-
-
Söderlund, V.1
Larsson, S.A.2
Jacobsson, H.3
-
95
-
-
84871611304
-
Ephedrine activates brown adipose tissue in lean but not obese humans
-
Carey AL, Formosa MF, Van Every B, Bertovic D, Eikelis N, Lambert GW, et al. Ephedrine activates brown adipose tissue in lean but not obese humans. Diabetologia. 2013; 56: 147-55.
-
(2013)
Diabetologia.
, vol.56
, pp. 147-155
-
-
Carey, A.L.1
Formosa, M.F.2
Van Every, B.3
Bertovic, D.4
Eikelis, N.5
Lambert, G.W.6
-
96
-
-
84862515329
-
Cold but not sympathomimetics activates human brown adipose tissue in vivo
-
Cypess AM, Chen YC, Sze C, Wang K, English J, Chan O, et al. Cold but not sympathomimetics activates human brown adipose tissue in vivo. Proc Natl Acad Sci U S A. 2012; 109: 10001-5.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 10001-10005
-
-
Cypess, A.M.1
Chen, Y.C.2
Sze, C.3
Wang, K.4
English, J.5
Chan, O.6
-
98
-
-
84888377939
-
Evidence against a beneficial effect of irisin in humans
-
Raschke S, Elsen M, Gassenhuber H, Sommerfeld M, Schwahn U, Brockmann B, et al. Evidence against a beneficial effect of irisin in humans. PLoS One. 2013; 8: e73680.
-
(2013)
PLoS One
, vol.8
, pp. e73680
-
-
Raschke, S.1
Elsen, M.2
Gassenhuber, H.3
Sommerfeld, M.4
Schwahn, U.5
Brockmann, B.6
-
99
-
-
84887069835
-
Irisin and exercise training in humans - Results from a randomized controlled training trial
-
Hecksteden A, Wegmann M, Steffen A, Kraushaar J, Morsch A, Ruppenthal S, et al. Irisin and exercise training in humans - results from a randomized controlled training trial. BMC Med. 2013; 11: 235.
-
(2013)
BMC Med.
, vol.11
, pp. 235
-
-
Hecksteden, A.1
Wegmann, M.2
Steffen, A.3
Kraushaar, J.4
Morsch, A.5
Ruppenthal, S.6
-
100
-
-
84886769757
-
Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health?
-
Pekkala S, Wiklund PK, Hulmi JJ, Ahtiainen JP, Horttanainen M, Pöllänen E, et al. Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health? J Physiol. 2013; 591: 5393-400.
-
(2013)
J Physiol.
, vol.591
, pp. 5393-5400
-
-
Pekkala, S.1
Wiklund, P.K.2
Hulmi, J.J.3
Ahtiainen, J.P.4
Horttanainen, M.5
Pöllänen, E.6
-
101
-
-
84895086158
-
The effects of acute and chronic exercise on PGC- 1α, irisin and browning of subcutaneous adipose tissue in humans
-
Norheim F, Langleite TM, Hjorth M, Holen T, Kielland A, Stadheim HK, et al. The effects of acute and chronic exercise on PGC- 1α, irisin and browning of subcutaneous adipose tissue in humans. FEBS J. 2014; 281: 739-49.
-
(2014)
FEBS J.
, vol.281
, pp. 739-749
-
-
Norheim, F.1
Langleite, T.M.2
Hjorth, M.3
Holen, T.4
Kielland, A.5
Stadheim, H.K.6
-
102
-
-
84893452569
-
Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans
-
Lee P, Linderman JD, Smith S, Brychta RJ, Wang J, Idelson C, et al. Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans. Cell Metab. 2014; 19: 302-9.
-
(2014)
Cell Metab.
, vol.19
, pp. 302-309
-
-
Lee, P.1
Linderman, J.D.2
Smith, S.3
Brychta, R.J.4
Wang, J.5
Idelson, C.6
-
103
-
-
84888386052
-
Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor?
-
Erickson HP. Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor? Adipocyte. 2013; 2: 289-93.
-
(2013)
Adipocyte.
, vol.2
, pp. 289-293
-
-
Erickson, H.P.1
-
104
-
-
84904471519
-
Inconsistency in circulating irisin levels: What is really happening?
-
Sanchis-Gomar F, Alis R, Pareja-Galeano H, Romagnoli M, Perez-Quilis C. Inconsistency in circulating irisin levels: what is really happening? Horm Metab Res. 2014; 46: 591-6.
-
(2014)
Horm Metab Res.
, vol.46
, pp. 591-596
-
-
Sanchis-Gomar, F.1
Alis, R.2
Pareja-Galeano, H.3
Romagnoli, M.4
Perez-Quilis, C.5
-
105
-
-
84920993496
-
Does IRISIN have a BRITE future as a therapeutic agent in humans?
-
Irving BA, Still CD, Argyropoulos G. Does IRISIN have a BRITE future as a therapeutic agent in humans? Curr Obes Rep. 2014; 3: 235-41.
-
(2014)
Curr Obes Rep.
, vol.3
, pp. 235-241
-
-
Irving, B.A.1
Still, C.D.2
Argyropoulos, G.3
-
106
-
-
84904417022
-
Browning of white fat: Does irisin play a role in humans?
-
Elsen M, Raschke S, Eckel J. Browning of white fat: does irisin play a role in humans? J Endocrinol. 2014; 222: R25-38.
-
(2014)
J Endocrinol.
, vol.222
, pp. R25-38
-
-
Elsen, M.1
Raschke, S.2
Eckel, J.3
-
107
-
-
84876133911
-
FNDC5/irisin is not only a myokine but also an adipokine
-
Roca-Rivada A, Castelao C, Senin LL, Landrove MO, Baltar J, Belén Crujeiras A, et al. FNDC5/irisin is not only a myokine but also an adipokine. PLoS One. 2013; 8: e60563.
-
(2013)
PLoS One
, vol.8
, pp. e60563
-
-
Roca-Rivada, A.1
Castelao, C.2
Senin, L.L.3
Landrove, M.O.4
Baltar, J.5
Belén Crujeiras, A.6
-
108
-
-
84896710569
-
Functional thermogenic beige adipogenesis is inducible in human neck fat
-
Lee P, Werner CD, Kebebew E, Celi FS. Functional thermogenic beige adipogenesis is inducible in human neck fat. Int J Obes (Lond). 2014; 38: 170-6.
-
(2014)
Int J Obes (Lond)
, vol.38
, pp. 170-176
-
-
Lee, P.1
Werner, C.D.2
Kebebew, E.3
Celi, F.S.4
-
109
-
-
79751503329
-
Brown adipose tissue activity controls triglyceride clearance
-
Bartelt A, Bruns OT, Reimer R, Hohenberg H, Ittrich H, Peldschus K, et al. Brown adipose tissue activity controls triglyceride clearance. Nat Med. 2011; 17: 200-5.
-
(2011)
Nat Med.
, vol.17
, pp. 200-205
-
-
Bartelt, A.1
Bruns, O.T.2
Reimer, R.3
Hohenberg, H.4
Ittrich, H.5
Peldschus, K.6
-
110
-
-
84887619281
-
Regulation of glucose homoeostasis by brown adipose tissue
-
Peirce V, Vidal-Puig A. Regulation of glucose homoeostasis by brown adipose tissue. Lancet Diabetes Endocrinol. 2013; 1: 353-60.
-
(2013)
Lancet Diabetes Endocrinol.
, vol.1
, pp. 353-360
-
-
Peirce, V.1
Vidal-Puig, A.2
-
111
-
-
78650945931
-
Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
-
Seale P, Conroe HM, Estall J, Kajimura S, Frontini A, Ishibashi J, et al. Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice. J Clin Invest. 2011; 121: 96-105.
-
(2011)
J Clin Invest.
, vol.121
, pp. 96-105
-
-
Seale, P.1
Conroe, H.M.2
Estall, J.3
Kajimura, S.4
Frontini, A.5
Ishibashi, J.6
-
112
-
-
84879921545
-
Shox2 is a molecular determinant of depot-specific adipocyte function
-
Lee KY, Yamamoto Y, Boucher J, Winnay JN, Gesta S, Cobb J, et al. Shox2 is a molecular determinant of depot-specific adipocyte function. Proc Natl Acad Sci U S A. 2013; 110: 11409-14.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 11409-11414
-
-
Lee, K.Y.1
Yamamoto, Y.2
Boucher, J.3
Winnay, J.N.4
Gesta, S.5
Cobb, J.6
-
113
-
-
34248372084
-
Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages
-
Timmons JA, Wennmalm K, Larsson O, Walden TB, Lassmann T, Petrovic N, et al. Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages. Proc Natl Acad Sci U S A. 2007; 104: 4401-6
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 4401-4406
-
-
Timmons, J.A.1
Wennmalm, K.2
Larsson, O.3
Walden, T.B.4
Lassmann, T.5
Petrovic, N.6
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