SCOPUS 정보 검색 플랫폼

Volumn 16, Issue 6, 2015, Pages 887-898

Tools of the Trade: Investigations into Design Strategies of Small Molecules to Target Components in Alzheimer's Disease

(2) Derrick, Jeffrey S a Lim, Mi Hee a

a Ulsan National Institute of Science and Technology (South Korea)

Author keywords

Alzheimer's disease; amyloid beta peptides; drug design; multifunctional small molecules; tau protein

Indexed keywords

ANTIAMYLOIDOGENIC AGENT; CHELATING AGENT; IONOPHORE; SMALL MOLECULE TRANSPORT AGENT; TAU PROTEIN; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; MOLECULAR LIBRARY;

ALZHEIMER DISEASE; ARTICLE; DRUG DESIGN; HUMAN; PRIORITY JOURNAL; ANIMAL; CHEMISTRY; METABOLISM; MOLECULAR LIBRARY; MOLECULARLY TARGETED THERAPY; PHARMACOLOGY; PROCEDURES; THERAPEUTIC USE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; DRUG DESIGN; HUMANS; MOLECULAR TARGETED THERAPY; SMALL MOLECULE LIBRARIES; TAU PROTEINS;

EID: 84926326017 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201402718 Document Type: Article

Times cited : (33)

References (97)

1
- 84889639581
- Alzheimer's Association, Alzheimer's Dementia 2014, 10, 1-67.
- (2014) Alzheimer's Dementia , vol.10 , pp. 1-67

2
- 84923191349
- (Ed.: T. Storr), Wiley
- M. W. Beck, A. S. Pithadia, A. S. DeToma, K. J. Korshavn, M. H. Lim, in Ligand Design in Medicinal Inorganic Chemistry (Ed.: T. Storr), Wiley, 2014, pp. 256-286
- (2014) Ligand Design in Medicinal Inorganic Chemistry , pp. 256-286
- Beck, M.W.¹ Pithadia, A.S.² DeToma, A.S.³ Korshavn, K.J.⁴ Lim, M.H.⁵

3
- 84907195362
- K. J. Barnham, A. I. Bush, Chem. Soc. Rev. 2014, 43, 6727-6749
- (2014) Chem. Soc. Rev. , vol.43 , pp. 6727-6749
- Barnham, K.J.¹ Bush, A.I.²

4
- 44849102395
- E. L. Que, D. W. Domaille, C. J. Chang, Chem. Rev. 2008, 108, 1517-1549
- (2008) Chem. Rev. , vol.108 , pp. 1517-1549
- Que, E.L.¹ Domaille, D.W.² Chang, C.J.³

5
- 84867460758
- K. P. Kepp, Chem. Rev. 2012, 112, 5193-5239
- (2012) Chem. Rev. , vol.112 , pp. 5193-5239
- Kepp, K.P.¹

6
- 70349923038
- R. Jakob-Roetne, H. Jacobsen, Angew. Chem. Int. Ed. 2009, 48, 3030-3059
- (2009) Angew. Chem. Int. Ed. , vol.48 , pp. 3030-3059
- Jakob-Roetne, R.¹ Jacobsen, H.²

7
- 77549084667
- Angew. Chem. 2009, 121, 3074-3105.
- (2009) Angew. Chem. , vol.121 , pp. 3074-3105

8
- 84908013710
- K. V. Sashidhara, R. K. Modukuri, P. Jadiya, K. B. Rao, T. Sharma, R. Haque, D. K. Singh, D. Banerjee, M. I. Siddiqi, A. Nazir, ACS Med. Chem. Lett. 2014, 5, 1099-1103
- (2014) ACS Med. Chem. Lett. , vol.5 , pp. 1099-1103
- Sashidhara, K.V.¹ Modukuri, R.K.² Jadiya, P.³ Rao, K.B.⁴ Sharma, T.⁵ Haque, R.⁶ Singh, D.K.⁷ Banerjee, D.⁸ Siddiqi, M.I.⁹ Nazir, A.¹⁰

9
- 84897930725
- D. Devos, C. Moreau, J. C. Devedjian, J. Kluza, M. Petrault, C. Laloux, A. Jonneaux, G. Ryckewaert, G. Garçon, N. Rouaix, A. Duhamel, P. Jissendi, K. Dujardin, F. Auger, L. Ravasi, L. Hopes, G. Grolez, W. Firdaus, B. Sablonnière, I. Strubi-Vuillaume, et al., Antioxid. Redox Signaling 2014, 21, 195-210
- (2014) Antioxid. Redox Signaling , vol.21 , pp. 195-210
- Devos, D.¹ Moreau, C.² Devedjian, J.C.³ Kluza, J.⁴ Petrault, M.⁵ Laloux, C.⁶ Jonneaux, A.⁷ Ryckewaert, G.⁸ Garçon, G.⁹ Rouaix, N.¹⁰ Duhamel, A.¹¹ Jissendi, P.¹² Dujardin, K.¹³ Auger, F.¹⁴ Ravasi, L.¹⁵ Hopes, L.¹⁶ Grolez, G.¹⁷ Firdaus, W.¹⁸ Sablonnière, B.¹⁹ Strubi-Vuillaume, I.²⁰ more..

10
- 46749100924
- A. I. Bush, R. E. Tanzi, Neurotherapeutics 2008, 5, 421-432
- (2008) Neurotherapeutics , vol.5 , pp. 421-432
- Bush, A.I.¹ Tanzi, R.E.²

11
- 23844482456
- T. Nguyen, A. Hamby, S. M. Massa, Proc. Natl. Acad. Sci. USA 2005, 102, 11840-11845
- (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 11840-11845
- Nguyen, T.¹ Hamby, A.² Massa, S.M.³

12
- 0242684415
- D. Kaur, F. Yantiri, S. Rajagopalan, J. Kumar, J. Q. Mo, R. Boonplueang, V. Viswanath, R. Jacobs, L. Yang, M. F. Beal, D. DiMonte, I. Volitaskis, L. Ellerby, R. A. Cherny, A. I. Bush, J. K. Andersen, Neuron 2003, 37, 899-909.
- (2003) Neuron , vol.37 , pp. 899-909
- Kaur, D.¹ Yantiri, F.² Rajagopalan, S.³ Kumar, J.⁴ Mo, J.Q.⁵ Boonplueang, R.⁶ Viswanath, V.⁷ Jacobs, R.⁸ Yang, L.⁹ Beal, M.F.¹⁰ Dimonte, D.¹¹ Volitaskis, I.¹² Ellerby, L.¹³ Cherny, R.A.¹⁴ Bush, A.I.¹⁵ Andersen, J.K.¹⁶

13
- 70350153272
- A. Rauk, Chem. Soc. Rev. 2009, 38, 2698-2715
- (2009) Chem. Soc. Rev. , vol.38 , pp. 2698-2715
- Rauk, A.¹

14
- 84878034899
- M. G. Savelieff, S. Lee, Y. Liu, M. H. Lim, ACS Chem. Biol. 2013, 8, 856-865
- (2013) ACS Chem. Biol. , vol.8 , pp. 856-865
- Savelieff, M.G.¹ Lee, S.² Liu, Y.³ Lim, M.H.⁴

15
- 39749196738
- A. Rauk, Dalton Trans. 2008, 1273-1282
- (2008) Dalton Trans. , pp. 1273-1282
- Rauk, A.¹

16
- 80155209561
- A. S. DeToma, S. Salamekh, A. Ramamoorthy, M. H. Lim, Chem. Soc. Rev. 2012, 41, 608-621
- (2012) Chem. Soc. Rev. , vol.41 , pp. 608-621
- DeToma, A.S.¹ Salamekh, S.² Ramamoorthy, A.³ Lim, M.H.⁴

17
- 84887048150
- P. Faller, C. Hureau, O. Berthoumieu, Inorg. Chem. 2013, 52, 12193-12206.
- (2013) Inorg. Chem. , vol.52 , pp. 12193-12206
- Faller, P.¹ Hureau, C.² Berthoumieu, O.³

18
- 84859651929
- A. S. Pithadia, M. H. Lim, Curr. Opin. Chem. Biol. 2012, 16, 67-73.
- (2012) Curr. Opin. Chem. Biol. , vol.16 , pp. 67-73
- Pithadia, A.S.¹ Lim, M.H.²

19
- 0027361281
- E. Köpke, Y.-C. Tung, S. Shaikh, A. D. C. Alonso, K. Iqbal, I. Grundke-Iqbal, J. Biol. Chem. 1993, 268, 24374-24384
- (1993) J. Biol. Chem. , vol.268 , pp. 24374-24384
- Köpke, E.¹ Tung, Y.-C.² Shaikh, S.³ Alonso, A.D.C.⁴ Iqbal, K.⁵ Grundke-Iqbal, I.⁶

20
- 0036724204
- A. Yamamoto, R.-W. Shin, K. Hasegawa, H. Naiki, H. Sato, F. Yoshimasu, T. Kitamoto, J. Neurochem. 2002, 82, 1137-1147
- (2002) J. Neurochem. , vol.82 , pp. 1137-1147
- Yamamoto, A.¹ Shin, R.-W.² Hasegawa, K.³ Naiki, H.⁴ Sato, H.⁵ Yoshimasu, F.⁶ Kitamoto, T.⁷

21
- 70350686620
- L. E. Scott, C. Orvig, Chem. Rev. 2009, 109, 4885-4910
- (2009) Chem. Rev. , vol.109 , pp. 4885-4910
- Scott, L.E.¹ Orvig, C.²

22
- 72949104344
- S. Bolognin, L. Messori, P. Zatta, Neuromol. Med. 2009, 11, 223-238.
- (2009) Neuromol. Med. , vol.11 , pp. 223-238
- Bolognin, S.¹ Messori, L.² Zatta, P.³

23
- 0032507975
- M. A. Lovell, J. D. Robertson, W. J. Teesdale, J. L. Campbell, W. R. Markesbery, J. Neurol. Sci. 1998, 158, 47-52
- (1998) J. Neurol. Sci. , vol.158 , pp. 47-52
- Lovell, M.A.¹ Robertson, J.D.² Teesdale, W.J.³ Campbell, J.L.⁴ Markesbery, W.R.⁵

24
- 84864532442
- J. H. Viles, Coord. Chem. Rev. 2012, 256, 2271-2284.
- (2012) Coord. Chem. Rev. , vol.256 , pp. 2271-2284
- Viles, J.H.¹

25
- 84862005631
- I. Solomonov, E. Korkotian, B. Born, Y. Feldman, A. Bitler, F. Rahimi, H. Li, G. Bitan, I. Sagi, J. Biol. Chem. 2012, 287, 20555-20564.
- (2012) J. Biol. Chem. , vol.287 , pp. 20555-20564
- Solomonov, I.¹ Korkotian, E.² Born, B.³ Feldman, Y.⁴ Bitler, A.⁵ Rahimi, F.⁶ Li, H.⁷ Bitan, G.⁸ Sagi, I.⁹

26
- 84906261439
- M. G. Savelieff, A. S. DeToma, J. S. Derrick, M. H. Lim, Acc. Chem. Res. 2014, 47, 2475-2482.
- (2014) Acc. Chem. Res. , vol.47 , pp. 2475-2482
- Savelieff, M.G.¹ DeToma, A.S.² Derrick, J.S.³ Lim, M.H.⁴

27
- 33746649088
- T. Hamaguchi, K. Ono, M. Yamada, Cell. Mol. Life Sci. 2006, 63, 1538-1552
- (2006) Cell. Mol. Life Sci. , vol.63 , pp. 1538-1552
- Hamaguchi, T.¹ Ono, K.² Yamada, M.³

28
- 84884769320
- B. Cheng, H. Gong, H. Xiao, R. B. Petersen, L. Zheng, K. Huang, Biochim. Biophys. Acta Gen. Subj. 2013, 1830, 4860-4871
- (2013) Biochim. Biophys. Acta Gen. Subj. , vol.1830 , pp. 4860-4871
- Cheng, B.¹ Gong, H.² Xiao, H.³ Petersen, R.B.⁴ Zheng, L.⁵ Huang, K.⁶

29
- 84864544333
- D. Valensin, C. Gabbiani, L. Messori, Coord. Chem. Rev. 2012, 256, 2357-2366
- (2012) Coord. Chem. Rev. , vol.256 , pp. 2357-2366
- Valensin, D.¹ Gabbiani, C.² Messori, L.³

30
- 70349093083
- F. Panza, V. Solfrizzi, V. Frisardi, C. Capurso, A. D'Introno, A. M. Colacicco, G. Vendemiale, A. Capurso, B. P. Imbimbo, Drugs Aging 2009, 26, 537-555
- (2009) Drugs Aging , vol.26 , pp. 537-555
- Panza, F.¹ Solfrizzi, V.² Frisardi, V.³ Capurso, C.⁴ D'Introno, A.⁵ Colacicco, A.M.⁶ Vendemiale, G.⁷ Capurso, A.⁸ Imbimbo, B.P.⁹

31
- 84903713725
- Q. Wang, X. Yu, L. Li, J. Zheng, Curr. Pharm. Des. 2014, 20, 1223-1243
- (2014) Curr. Pharm. Des. , vol.20 , pp. 1223-1243
- Wang, Q.¹ Yu, X.² Li, L.³ Zheng, J.⁴

32
- 84907855054
- G. R. Walke, S. Rapole, P. P. Kulkarni, Inorg. Chem. 2014, 53, 10003-10005
- (2014) Inorg. Chem. , vol.53 , pp. 10003-10005
- Walke, G.R.¹ Rapole, S.² Kulkarni, P.P.³

33
- 84894439258
- C. Hureau, P. Faller, Dalton Trans. 2014, 43, 4233-4237
- (2014) Dalton Trans. , vol.43 , pp. 4233-4237
- Hureau, C.¹ Faller, P.²

34
- 84875203048
- V. B. Kenche, L. W. Hung, K. Perez, I. Volitakes, G. Ciccotosto, J. Kwok, N. Critch, N. Sherratt, M. Cortes, V. Lal, C. L. Masters, K. Murakami, R. Cappai, P. A. Adlard, K. J. Barnham, Angew. Chem. Int. Ed. 2013, 52, 3374-3378
- (2013) Angew. Chem. Int. Ed. , vol.52 , pp. 3374-3378
- Kenche, V.B.¹ Hung, L.W.² Perez, K.³ Volitakes, I.⁴ Ciccotosto, G.⁵ Kwok, J.⁶ Critch, N.⁷ Sherratt, N.⁸ Cortes, M.⁹ Lal, V.¹⁰ Masters, C.L.¹¹ Murakami, K.¹² Cappai, R.¹³ Adlard, P.A.¹⁴ Barnham, K.J.¹⁵

35
- 84904543474
- Angew. Chem. 2013, 125, 3458-3462
- (2013) Angew. Chem. , vol.125 , pp. 3458-3462

36
- 84874091189
- F. Collin, I. Sasaki, H. Eury, P. Faller, C. Hureau, Chem. Commun. 2013, 49, 2130-2132.
- (2013) Chem. Commun. , vol.49 , pp. 2130-2132
- Collin, F.¹ Sasaki, I.² Eury, H.³ Faller, P.⁴ Hureau, C.⁵

37
- 48249092311
- W.-F. Xue, S. W. Homans, S. E. Radford, Proc. Natl. Acad. Sci. USA 2008, 105, 8926-8931.
- (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 8926-8931
- Xue, W.-F.¹ Homans, S.W.² Radford, S.E.³

38
- 0033535504
- B. De Strooper, W. Annaert, P. Cupers, P. Saftig, K. Craessaerts, J. S. Mumm, E. H. Schroeter, V. Schrijvers, M. S. Wolfe, W. J. Ray, A. Goate, R. Kopan, Nature 1999, 398, 518-522.
- (1999) Nature , vol.398 , pp. 518-522
- De Strooper, B.¹ Annaert, W.² Cupers, P.³ Saftig, P.⁴ Craessaerts, K.⁵ Mumm, J.S.⁶ Schroeter, E.H.⁷ Schrijvers, V.⁸ Wolfe, M.S.⁹ Ray, W.J.¹⁰ Goate, A.¹¹ Kopan, R.¹²

39
- 84864443157
- L. Fülöp, I. M. Mándity, G. Juhász, V. Szegedi, A. Hetényi, E. Wéber, Z. Bozsó, D. Simon, M. Benko{combining double acute accent}, Z. Király, T. A. Martinek, PLOS One 2012, 7, e39485.
- (2012) PLOS One , vol.7 , pp. e39485
- Fülöp, L.¹ Mándity, I.M.² Juhász, G.³ Szegedi, V.⁴ Hetényi, A.⁵ Wéber, E.⁶ Bozsó, Z.⁷ Simon, D.⁸ Benko, M.⁹ Király, Z.¹⁰ Martinek, T.A.¹¹

40
- 84874590103
- Y. Imamura, N. Umezawa, S. Osawa, N. Shimada, T. Higo, S. Yokoshima, T. Fukuyama, T. Iwatsubo, N. Kato, T. Tomita, T. Higuchi, J. Med. Chem. 2013, 56, 1443-1454.
- (2013) J. Med. Chem. , vol.56 , pp. 1443-1454
- Imamura, Y.¹ Umezawa, N.² Osawa, S.³ Shimada, N.⁴ Higo, T.⁵ Yokoshima, S.⁶ Fukuyama, T.⁷ Iwatsubo, T.⁸ Kato, N.⁹ Tomita, T.¹⁰ Higuchi, T.¹¹

41
- 10744219775
- T. Kimura, D. Shuto, S. Kasai, P. Liu, K. Hidaka, T. Hamada, Y. Hayashi, C. Hattori, M. Asai, S. Kitazume, T. C. Saido, S. Ishiura, Y. Kiso, Bioorg. Med. Chem. Lett. 2004, 14, 1527-1531
- (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 1527-1531
- Kimura, T.¹ Shuto, D.² Kasai, S.³ Liu, P.⁴ Hidaka, K.⁵ Hamada, T.⁶ Hayashi, Y.⁷ Hattori, C.⁸ Asai, M.⁹ Kitazume, S.¹⁰ Saido, T.C.¹¹ Ishiura, S.¹² Kiso, Y.¹³

42
- 9644266667
- T. Kimura, D. Shuto, Y. Hamada, N. Igawa, S. Kasai, P. Liu, K. Hidaka, T. Hamada, Y. Hayashi, Y. Kiso, Bioorg. Med. Chem. Lett. 2005, 15, 211-215.
- (2005) Bioorg. Med. Chem. Lett. , vol.15 , pp. 211-215
- Kimura, T.¹ Shuto, D.² Hamada, Y.³ Igawa, N.⁴ Kasai, S.⁵ Liu, P.⁶ Hidaka, K.⁷ Hamada, T.⁸ Hayashi, Y.⁹ Kiso, Y.¹⁰

43
- 84907200610
- H. J. Lee, K. J. Korshavn, A. Kochi, J. S. Derrick, M. H. Lim, Chem. Soc. Rev. 2014, 43, 6672-6682.
- (2014) Chem. Soc. Rev. , vol.43 , pp. 6672-6682
- Lee, H.J.¹ Korshavn, K.J.² Kochi, A.³ Derrick, J.S.⁴ Lim, M.H.⁵

44
- 44349120174
- K. J. Barnham, V. B. Kenche, G. D. Ciccotosto, D. P. Smith, D. J. Tew, X. Liu, K. Perez, G. A. Cranston, T. J. Johanssen, I. Volitakis, A. I. Bush, C. L. Masters, A. R. White, J. P. Smith, R. A. Cherny, R. Cappai, Proc. Natl. Acad. Sci. USA 2008, 105, 6813-6818.
- (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 6813-6818
- Barnham, K.J.¹ Kenche, V.B.² Ciccotosto, G.D.³ Smith, D.P.⁴ Tew, D.J.⁵ Liu, X.⁶ Perez, K.⁷ Cranston, G.A.⁸ Johanssen, T.J.⁹ Volitakis, I.¹⁰ Bush, A.I.¹¹ Masters, C.L.¹² White, A.R.¹³ Smith, J.P.¹⁴ Cherny, R.A.¹⁵ Cappai, R.¹⁶

45
- 0029896354
- B. A. Yankner, Neuron 1996, 16, 921-932
- (1996) Neuron , vol.16 , pp. 921-932
- Yankner, B.A.¹

46
- 0028172886
- A. Lorenzo, B. A. Yankner, Proc. Natl. Acad. Sci. USA 1994, 91, 12243-12247.
- (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12243-12247
- Lorenzo, A.¹ Yankner, B.A.²

47
- 67649803877
- S. Bolognin, D. Drago, L. Messori, P. Zatta, Med. Res. Rev. 2009, 29, 547-570.
- (2009) Med. Res. Rev. , vol.29 , pp. 547-570
- Bolognin, S.¹ Drago, D.² Messori, L.³ Zatta, P.⁴

48
- 29044438902
- A. Gaeta, R. C. Hider, Br. J. Pharmacol. 2005, 146, 1041-1059.
- (2005) Br. J. Pharmacol. , vol.146 , pp. 1041-1059
- Gaeta, A.¹ Hider, R.C.²

49
- 67650759968
- H. Zheng, M. B. H. Youdim, M. Fridkin, J. Med. Chem. 2009, 52, 4095-4098
- (2009) J. Med. Chem. , vol.52 , pp. 4095-4098
- Zheng, H.¹ Youdim, M.B.H.² Fridkin, M.³

50
- 33748202940
- G. Liu, P. Men, P. L. R. Harris, R. K. Rolston, G. Perry, M. A. Smith, Neurosci. Lett. 2006, 406, 189-193
- (2006) Neurosci. Lett. , vol.406 , pp. 189-193
- Liu, G.¹ Men, P.² Harris, P.L.R.³ Rolston, R.K.⁴ Perry, G.⁵ Smith, M.A.⁶

51
- 64049104164
- G. Liu, P. Men, W. Kudo, G. Perry, M. A. Smith, Neurosci. Lett. 2009, 455, 187-190
- (2009) Neurosci. Lett. , vol.455 , pp. 187-190
- Liu, G.¹ Men, P.² Kudo, W.³ Perry, G.⁴ Smith, M.A.⁵

52
- 70449529637
- R. Gabathuler, Neurobiol. Dis. 2010, 37, 48-57
- (2010) Neurobiol. Dis. , vol.37 , pp. 48-57
- Gabathuler, R.¹

53
- 0033981358
- D. E. Clark, S. D. Pickett, Drug Discovery Today 2000, 5, 49-58.
- (2000) Drug Discovery Today , vol.5 , pp. 49-58
- Clark, D.E.¹ Pickett, S.D.²

54
- 77149144132
- L. R. Perez, K. J. Franz, Dalton Trans. 2010, 39, 2177-2187.
- (2010) Dalton Trans. , vol.39 , pp. 2177-2187
- Perez, L.R.¹ Franz, K.J.²

55
- 0035289779
- C. A. Lipinski, F. Lombardo, B. W. Dominy, P. J. Feeney, Adv. Drug Delivery Rev. 2001, 46, 3-26.
- (2001) Adv. Drug Delivery Rev. , vol.46 , pp. 3-26
- Lipinski, C.A.¹ Lombardo, F.² Dominy, B.W.³ Feeney, P.J.⁴

56
- 84892177268
- S. Lee, X. Zheng, J. Krishnamoorthy, M. G. Savelieff, H. M. Park, J. R. Brender, J. H. Kim, J. S. Derrick, A. Kochi, H. J. Lee, C. Kim, A. Ramamoorthy, M. T. Bowers, M. H. Lim, J. Am. Chem. Soc. 2014, 136, 299-310.
- (2014) J. Am. Chem. Soc. , vol.136 , pp. 299-310
- Lee, S.¹ Zheng, X.² Krishnamoorthy, J.³ Savelieff, M.G.⁴ Park, H.M.⁵ Brender, J.R.⁶ Kim, J.H.⁷ Derrick, J.S.⁸ Kochi, A.⁹ Lee, H.J.¹⁰ Kim, C.¹¹ Ramamoorthy, A.¹² Bowers, M.T.¹³ Lim, M.H.¹⁴

57
- 57649130599
- W.-H. Wu, P. Lei, Q. Liu, J. Hu, A. P. Gunn, M.-S. Chen, Y.-F. Rui, X.-Y. Su, Z.-P. Xie, Y.-F. Zhao, A. I. Bush, Y.-M. Li, J. Biol. Chem. 2008, 283, 31657-31664.
- (2008) J. Biol. Chem. , vol.283 , pp. 31657-31664
- Wu, W.-H.¹ Lei, P.² Liu, Q.³ Hu, J.⁴ Gunn, A.P.⁵ Chen, M.-S.⁶ Rui, Y.-F.⁷ Su, X.-Y.⁸ Xie, Z.-P.⁹ Zhao, Y.-F.¹⁰ Bush, A.I.¹¹ Li, Y.-M.¹²

58
- 75649105423
- M. G. Dickens, K. J. Franz, ChemBioChem 2010, 11, 59-62.
- (2010) ChemBioChem , vol.11 , pp. 59-62
- Dickens, M.G.¹ Franz, K.J.²

59
- 10744224267
- C. W. Ritchie, A. I. Bush, A. Mackinnon, S. Macfarlane, M. Mastwyk, L. MacGregor, L. Kiers, R. Cherny, Q.-X. Li, A. Tammer, D. Carrington, C. Mavros, I. Volitakis, M. Xilinas, D. Ames, S. Davis, K. Beyreuther, R. E. Tanzi, C. L. Masters, Arch. Neurol. 2003, 60, 1685-1691
- (2003) Arch. Neurol. , vol.60 , pp. 1685-1691
- Ritchie, C.W.¹ Bush, A.I.² Mackinnon, A.³ Macfarlane, S.⁴ Mastwyk, M.⁵ MacGregor, L.⁶ Kiers, L.⁷ Cherny, R.⁸ Li, Q.-X.⁹ Tammer, A.¹⁰ Carrington, D.¹¹ Mavros, C.¹² Volitakis, I.¹³ Xilinas, M.¹⁴ Ames, D.¹⁵ Davis, S.¹⁶ Beyreuther, K.¹⁷ Tanzi, R.E.¹⁸ Masters, C.L.¹⁹

60
- 35748959686
- A. Caragounis, T. Du, G. Filiz, K. M. Laughton, I. Volitakis, R. A. Sharples, R. A. Cherny, C. L. Masters, S. C. Drew, A. F. Hill, Q.-X. Li, P. J. Crouch, K. J. Barnham, A. R. White, Biochem. J. 2007, 407, 435-450
- (2007) Biochem. J. , vol.407 , pp. 435-450
- Caragounis, A.¹ Du, T.² Filiz, G.³ Laughton, K.M.⁴ Volitakis, I.⁵ Sharples, R.A.⁶ Cherny, R.A.⁷ Masters, C.L.⁸ Drew, S.C.⁹ Hill, A.F.¹⁰ Li, Q.-X.¹¹ Crouch, P.J.¹² Barnham, K.J.¹³ White, A.R.¹⁴

61
- 0034964390
- R. A. Cherny, C. S. Atwood, M. E. Xilinas, D. N. Gray, W. D. Jones, C. A. McLean, K. J. Barnham, I. Volitakis, F. W. Fraser, Y.-S. Kim, X. Huang, L. E. Goldstein, R. D. Moir, J. T. Lim, K. Beyreuther, H. Zheng, R. E. Tanzi, C. L. Masters, A. I. Bush, Neuron 2001, 30, 665-676
- (2001) Neuron , vol.30 , pp. 665-676
- Cherny, R.A.¹ Atwood, C.S.² Xilinas, M.E.³ Gray, D.N.⁴ Jones, W.D.⁵ McLean, C.A.⁶ Barnham, K.J.⁷ Volitakis, I.⁸ Fraser, F.W.⁹ Kim, Y.-S.¹⁰ Huang, X.¹¹ Goldstein, L.E.¹² Moir, R.D.¹³ Lim, J.T.¹⁴ Beyreuther, K.¹⁵ Zheng, H.¹⁶ Tanzi, R.E.¹⁷ Masters, C.L.¹⁸ Bush, A.I.¹⁹

62
- 40149109494
- G. Filiz, A. Caragounis, L. Bica, T. Du, C. L. Masters, P. J. Crouch, A. R. White, Int. J. Biochem. Cell Biol. 2008, 40, 1030-1042
- (2008) Int. J. Biochem. Cell Biol. , vol.40 , pp. 1030-1042
- Filiz, G.¹ Caragounis, A.² Bica, L.³ Du, T.⁴ Masters, C.L.⁵ Crouch, P.J.⁶ White, A.R.⁷

63
- 70350597464
- A. M. Mancino, S. S. Hindo, A. Kochi, M. H. Lim, Inorg. Chem. 2009, 48, 9596-9598
- (2009) Inorg. Chem. , vol.48 , pp. 9596-9598
- Mancino, A.M.¹ Hindo, S.S.² Kochi, A.³ Lim, M.H.⁴

64
- 84856280358
- S. R. Bareggi, U. Cornelli, CNS Neurosci. Ther. 2012, 18, 41-46.
- (2012) CNS Neurosci. Ther. , vol.18 , pp. 41-46
- Bareggi, S.R.¹ Cornelli, U.²

65
- 48949096186
- N. R. Relkin, Lancet Neurol. 2008, 7, 762-763.
- (2008) Lancet Neurol. , vol.7 , pp. 762-763
- Relkin, N.R.¹

66
- 46149107512
- P. A. Adlard, R. A. Cherny, D. I. Finkelstein, E. Gautier, E. Robb, M. Cortes, I. Volitakis, X. Liu, J. P. Smith, K. Perez, K. Laughton, Q.-X. Li, S. A. Charman, J. A. Nicolazzo, S. Wilkins, K. Deleva, T. Lynch, G. Kok, C. W. Ritchie, R. E. Tanzi, et al., Neuron 2008, 59, 43-55.
- (2008) Neuron , vol.59 , pp. 43-55
- Adlard, P.A.¹ Cherny, R.A.² Finkelstein, D.I.³ Gautier, E.⁴ Robb, E.⁵ Cortes, M.⁶ Volitakis, I.⁷ Liu, X.⁸ Smith, J.P.⁹ Perez, K.¹⁰ Laughton, K.¹¹ Li, Q.-X.¹² Charman, S.A.¹³ Nicolazzo, J.A.¹⁴ Wilkins, S.¹⁵ Deleva, K.¹⁶ Lynch, T.¹⁷ Kok, G.¹⁸ Ritchie, C.W.¹⁹ Tanzi, R.E.²⁰ more..

67
- 84875177189
- M. B. H. Youdim, Exp. Neurobiol. 2010, 19, 1-14
- (2010) Exp. Neurobiol. , vol.19 , pp. 1-14
- Youdim, M.B.H.¹

68
- 84864566040
- C. Rodríguez-Rodríguez, M. Telpoukhovskaia, C. Orvig, Coord. Chem. Rev. 2012, 256, 2308-2332
- (2012) Coord. Chem. Rev. , vol.256 , pp. 2308-2332
- Rodríguez-Rodríguez, C.¹ Telpoukhovskaia, M.² Orvig, C.³

69
- 55249106710
- D. Munoz-Torrero, Curr. Med. Chem. 2008, 15, 2433-2455.
- (2008) Curr. Med. Chem. , vol.15 , pp. 2433-2455
- Munoz-Torrero, D.¹

70
- 78650669293
- J.-S. Choi, J. J. Braymer, R. P. R. Nanga, A. Ramamoorthy, M. H. Lim, Proc. Natl. Acad. Sci. USA 2010, 107, 21990-21995
- (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 21990-21995
- Choi, J.-S.¹ Braymer, J.J.² Nanga, R.P.R.³ Ramamoorthy, A.⁴ Lim, M.H.⁵

71
- 80455137236
- W. J. Geldenhuys, K. S. Ko, H. Stinnett, C. J. Van der Schyf, M. H. Lim, Med. Chem. Commun. 2011, 2, 1099-1103.
- (2011) Med. Chem. Commun. , vol.2 , pp. 1099-1103
- Geldenhuys, W.J.¹ Ko, K.S.² Stinnett, H.³ Van Der Schyf, C.J.⁴ Lim, M.H.⁵

72
- 84923167087
- M. W. Beck, S. B. Oh, R. A. Kerr, H. J. Lee, S. H. Kim, S. Kim, M. Jang, B. T. Ruotolo, J.-Y. Lee, M. H. Lim, Chemi. Sci. 2015, 6, 1879-1886.
- (2015) Chemi. Sci. , vol.6 , pp. 1879-1886
- Beck, M.W.¹ Oh, S.B.² Kerr, R.A.³ Lee, H.J.⁴ Kim, S.H.⁵ Kim, S.⁶ Jang, M.⁷ Ruotolo, B.T.⁸ Lee, J.-Y.⁹ Lim, M.H.¹⁰

73
- 84867386502
- L. Huang, C. Lu, Y. Sun, F. Mao, Z. Luo, T. Su, H. Jiang, W. Shan, X. Li, J. Med. Chem. 2012, 55, 8483-8492
- (2012) J. Med. Chem. , vol.55 , pp. 8483-8492
- Huang, L.¹ Lu, C.² Sun, Y.³ Mao, F.⁴ Luo, Z.⁵ Su, T.⁶ Jiang, H.⁷ Shan, W.⁸ Li, X.⁹

74
- 25644461154
- H. Zheng, S. Gal, L. M. Weiner, O. Bar-Am, A. Warshawsky, M. Fridkin, M. B. H. Youdim, J. Neurochem. 2005, 95, 68-78
- (2005) J. Neurochem. , vol.95 , pp. 68-78
- Zheng, H.¹ Gal, S.² Weiner, L.M.³ Bar-Am, O.⁴ Warshawsky, A.⁵ Fridkin, M.⁶ Youdim, M.B.H.⁷

75
- 84863896457
- L. Kupershmidt, T. Amit, O. Bar-Am, M. B. H. Youdim, O. Weinreb, Antioxid. Redox Signaling 2012, 17, 860-877.
- (2012) Antioxid. Redox Signaling , vol.17 , pp. 860-877
- Kupershmidt, L.¹ Amit, T.² Bar-Am, O.³ Youdim, M.B.H.⁴ Weinreb, O.⁵

76
- 79955636221
- L. E. Scott, M. Telpoukhovskaia, C. Rodríguez-Rodríguez, M. Merkel, M. L. Bowen, B. D. G. Page, D. E. Green, T. Storr, F. Thomas, D. D. Allen, P. R. Lockman, B. O. Patrick, M. J. Adam, C. Orvig, Chem. Sci. 2011, 2, 642-648
- (2011) Chem. Sci. , vol.2 , pp. 642-648
- Scott, L.E.¹ Telpoukhovskaia, M.² Rodríguez-Rodríguez, C.³ Merkel, M.⁴ Bowen, M.L.⁵ Page, B.D.G.⁶ Green, D.E.⁷ Storr, T.⁸ Thomas, F.⁹ Allen, D.D.¹⁰ Lockman, P.R.¹¹ Patrick, B.O.¹² Adam, M.J.¹³ Orvig, C.¹⁴

77
- 34248208975
- H. Schugar, D. E. Green, M. L. Bowen, L. E. Scott, T. Storr, K. Böhmerle, F. Thomas, D. D. Allen, P. R. Lockman, M. Merkel, K. H. Thompson, C. Orvig, Angew. Chem. Int. Ed. 2007, 46, 1716-1718
- (2007) Angew. Chem. Int. Ed. , vol.46 , pp. 1716-1718
- Schugar, H.¹ Green, D.E.² Bowen, M.L.³ Scott, L.E.⁴ Storr, T.⁵ Böhmerle, K.⁶ Thomas, F.⁷ Allen, D.D.⁸ Lockman, P.R.⁹ Merkel, M.¹⁰ Thompson, K.H.¹¹ Orvig, C.¹²

78
- 60849111289
- Angew. Chem. 2007, 119, 1746-1748.
- (2007) Angew. Chem. , vol.119 , pp. 1746-1748

79
- 84872587279
- F. Hernandez, J. J. Lucas, J. Avila, J. Alzheimer's Dis. 2013, 33, S141-144
- (2013) J. Alzheimer's Dis. , vol.33 , pp. S141-S144
- Hernandez, F.¹ Lucas, J.J.² Avila, J.³

80
- 80053212816
- R. Medeiros, D. Baglietto-Vargas, F. M. LaFerla, CNS Neurosci. Ther. 2011, 17, 514-524
- (2011) CNS Neurosci. Ther. , vol.17 , pp. 514-524
- Medeiros, R.¹ Baglietto-Vargas, D.² LaFerla, F.M.³

81
- 68949150683
- A. Takashima, J. Alzheimer's Dis. 2009, 17, 729-736
- (2009) J. Alzheimer's Dis. , vol.17 , pp. 729-736
- Takashima, A.¹

82
- 58849143335
- H.-C. Huang, Z.-F. Jiang, J. Alzheimer's Dis. 2009, 16, 15-27.
- (2009) J. Alzheimer's Dis. , vol.16 , pp. 15-27
- Huang, H.-C.¹ Jiang, Z.-F.²

83
- 32444432146
- J.-P. Guo, T. Arai, J. Miklossy, P. L. McGeer, Proc. Natl. Acad. Sci. USA 2006, 103, 1953-1958.
- (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 1953-1958
- Guo, J.-P.¹ Arai, T.² Miklossy, J.³ McGeer, P.L.⁴

84
- 53749090208
- A. Soragni, B. Zambelli, M. D. Mukrasch, J. Biernat, S. Jeganathan, C. Griesinger, S. Ciurli, E. Mandelkow, M. Zweckstetter, Biochemistry 2008, 47, 10841-10851
- (2008) Biochemistry , vol.47 , pp. 10841-10851
- Soragni, A.¹ Zambelli, B.² Mukrasch, M.D.³ Biernat, J.⁴ Jeganathan, S.⁵ Griesinger, C.⁶ Ciurli, S.⁷ Mandelkow, E.⁸ Zweckstetter, M.⁹

85
- 27744565566
- Q.-F. Ma, Y.-M. Li, J.-T. Du, K. Kanazawa, T. Nemoto, H. Nakanishi, Y.-F. Zhao, Biopolymers 2005, 79, 74-85
- (2005) Biopolymers , vol.79 , pp. 74-85
- Ma, Q.-F.¹ Li, Y.-M.² Du, J.-T.³ Kanazawa, K.⁴ Nemoto, T.⁵ Nakanishi, H.⁶ Zhao, Y.-F.⁷

86
- 33645407628
- Q. Ma, Y. Li, J. Du, H. Liu, K. Kanazawa, T. Nemoto, H. Nakanishi, Y. Zhao, Peptides 2006, 27, 841-849.
- (2006) Peptides , vol.27 , pp. 841-849
- Ma, Q.¹ Li, Y.² Du, J.³ Liu, H.⁴ Kanazawa, K.⁵ Nemoto, T.⁶ Nakanishi, H.⁷ Zhao, Y.⁸

87
- 35348982797
- L.-X. Zhou, J.-T. Du, Z.-Y. Zeng, W.-H. Wu, Y.-F. Zhao, K. Kanazawa, Y. Ishizuka, T. Nemoto, H. Nakanishi, Y.-M. Li, Peptides 2007, 28, 2229-2234.
- (2007) Peptides , vol.28 , pp. 2229-2234
- Zhou, L.-X.¹ Du, J.-T.² Zeng, Z.-Y.³ Wu, W.-H.⁴ Zhao, Y.-F.⁵ Kanazawa, K.⁶ Ishizuka, Y.⁷ Nemoto, T.⁸ Nakanishi, H.⁹ Li, Y.-M.¹⁰

88
- 0036724204
- A. Yamamoto, R.-W. Shin, K. Hasegawa, H. Naiki, H. Sato, F. Yoshimasu, T. Kitamoto, J. Neurochem. 2002, 82, 1137-1147.
- (2002) J. Neurochem. , vol.82 , pp. 1137-1147
- Yamamoto, A.¹ Shin, R.-W.² Hasegawa, K.³ Naiki, H.⁴ Sato, H.⁵ Yoshimasu, F.⁶ Kitamoto, T.⁷

89
- 34248586955
- X.-Y. Su, W.-H. Wu, Z.-P. Huang, J. Hu, P. Lei, C.-H. Yu, Y.-F. Zhao, Y.-M. Li, Biochem. Biophys. Res. Commun. 2007, 358, 661-665.
- (2007) Biochem. Biophys. Res. Commun. , vol.358 , pp. 661-665
- Su, X.-Y.¹ Wu, W.-H.² Huang, Z.-P.³ Hu, J.⁴ Lei, P.⁵ Yu, C.-H.⁶ Zhao, Y.-F.⁷ Li, Y.-M.⁸

90
- 77952549757
- T. E. Golde, L. Petrucelli, J. Lewis, Exp. Neurol. 2010, 223, 252-266
- (2010) Exp. Neurol. , vol.223 , pp. 252-266
- Golde, T.E.¹ Petrucelli, L.² Lewis, J.³

91
- 84897954153
- M. Medina, J. Avila, Biochem. Pharmacol. 2014, 88, 540-547.
- (2014) Biochem. Pharmacol. , vol.88 , pp. 540-547
- Medina, M.¹ Avila, J.²

92
- 84868514765
- C. Ballatore, K. R. Brunden, D. M. Huryn, J. Q. Trojanowski, V. M.-Y. Lee, A. B. Smith III, J. Med. Chem. 2012, 55, 8979-8996
- (2012) J. Med. Chem. , vol.55 , pp. 8979-8996
- Ballatore, C.¹ Brunden, K.R.² Huryn, D.M.³ Trojanowski, J.Q.⁴ Lee, V.M.-Y.⁵ Smith, A.B.⁶

93
- 33644983367
- P.-K. Li, B. Pandit, D. L. Sackett, Z. Hu, J. Zink, J. Zhi, D. Freeman, R. W. Robey, K. Werbovetz, A. Lewis, C. Li, Mol. Cancer Ther. 2006, 5, 450-456.
- (2006) Mol. Cancer Ther. , vol.5 , pp. 450-456
- Li, P.-K.¹ Pandit, B.² Sackett, D.L.³ Hu, Z.⁴ Zink, J.⁵ Zhi, J.⁶ Freeman, D.⁷ Robey, R.W.⁸ Werbovetz, K.⁹ Lewis, A.¹⁰ Li, C.¹¹

94
- 84925883347
- K. R. Brunden, J. Q. Trojanowski, A. B. Smith III, V. M.-Y. Lee, C. Ballatore, Bioorg. Med. Chem. 2014, 22, 5040-5049.
- (2014) Bioorg. Med. Chem. , vol.22 , pp. 5040-5049
- Brunden, K.R.¹ Trojanowski, J.Q.² Smith, A.B.³ Lee, V.M.-Y.⁴ Ballatore, C.⁵

95
- 13244295499
- M. L. Michaelis, S. Ansar, Y. Chen, E. R. Reiff, K. I. Seyb, R. H. Himes, K. L. Audus, G. I. Georg, J. Pharmacol. Exp. Ther. 2005, 312, 659-668.
- (2005) J. Pharmacol. Exp. Ther. , vol.312 , pp. 659-668
- Michaelis, M.L.¹ Ansar, S.² Chen, Y.³ Reiff, E.R.⁴ Seyb, K.I.⁵ Himes, R.H.⁶ Audus, K.L.⁷ Georg, G.I.⁸

96
- 0033102385
- L. A. Amos, J. Löwe, Chem. Biol. 1999, 6, R65-R69.
- (1999) Chem. Biol. , vol.6 , pp. R65-R69
- Amos, L.A.¹ Löwe, J.²

97
- 77949272212
- S. Connelly, S. Choi, S. M. Johnson, J. W. Kelly, I. A. Wilson, Curr. Opin. Struct. Biol. 2010, 20, 54-62.
- (2010) Curr. Opin. Struct. Biol. , vol.20 , pp. 54-62
- Connelly, S.¹ Choi, S.² Johnson, S.M.³ Kelly, J.W.⁴ Wilson, I.A.⁵

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