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Mattson MP. Metal-catalyzed disruption of membrane protein and lipid signaling in the pathogenesis of neurodegenerative disorders. Ann N Y Acad Sci 2004;1012:37-50.
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Mattson, M.P.1
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53
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Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse model
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Nguyen, T, Hamby, A, Massa, SM. Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse model. Proc Natl Acad Sci USA 2005;16:11840-11845.
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Proc Natl Acad Sci USA
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Nguyen, T.1
Hamby, A.2
Massa, S.M.3
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54
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17144404213
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Anticancer activity of the antibiotic Clioquinol
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Describes the drug's activity as an anticancer agent
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Ding W-Q, Liu B, Vaught JL, Yamauchi H, Lind SE. Anticancer activity of the antibiotic Clioquinol. Cancer Res 2005;65:3389-3395. Describes the drug's activity as an anticancer agent.
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Cancer Res
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Ding, W.-Q.1
Liu, B.2
Vaught, J.L.3
Yamauchi, H.4
Lind, S.E.5
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55
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53249153476
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Zinc-binding compounds induce cancer cell death via distinct modes of action
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Ding WQ, Yu HJ, Lind SE. Zinc-binding compounds induce cancer cell death via distinct modes of action. Cancer Lett 2008;271:251-259.
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Cancer Lett
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Ding, W.Q.1
Yu, H.J.2
Lind, S.E.3
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56
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0031693030
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Transmethylation reactions and autoradiographic distribution of vitamin B12: Effects of clioquinol treatment in mice
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Interesting description of toxic mechanism
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Yassin MS, Ekblom J, Löfberg C, Oreland L. Transmethylation reactions and autoradiographic distribution of vitamin B12: Effects of clioquinol treatment in mice. Jpn J Pharmacol 1998;78:55-56. Interesting description of toxic mechanism.
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Jpn J Pharmacol
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, pp. 55-56
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Yassin, M.S.1
Ekblom, J.2
Löfberg, C.3
Oreland, L.4
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57
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18444399243
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Treatment of Alzheimer's disease with clioquinol
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The clinical efficacy of clioquinol in AD
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Regland B, Lehmann W, Abedini I, et al. Treatment of Alzheimer's disease with clioquinol. Dement Geriatr Cogn Disord 2001;12:408-414. The clinical efficacy of clioquinol in AD.
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Dement Geriatr Cogn Disord
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Regland, B.1
Lehmann, W.2
Abedini, I.3
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58
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10744224267
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Metal-protein attenuation with clioquinol targeting Abeta amyloid deposition and toxicity in Alzheimer's disease: A pilot phase 2 clinical trial
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The effects of clioquinol in ALZ patients with moderate AD
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Ritchie CW, Bush AI, Mackinnon A, et al. Metal-protein attenuation with clioquinol targeting Abeta amyloid deposition and toxicity in Alzheimer's disease: A pilot phase 2 clinical trial. Arch Neurol 2003;60:1685-1691. The effects of clioquinol in ALZ patients with moderate AD.
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Arch Neurol
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Ritchie, C.W.1
Bush, A.I.2
Mackinnon, A.3
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59
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44949217583
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Metal protein attenuating compounds for the treatment of Alzheimer's disease
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DOI: An interesting review indicating that there is a lack of evidence as to whether clioquinol has any positive clinical benefit in patients with AD
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Sampson EL, Jenagaratnam L, McShane R. Metal protein attenuating compounds for the treatment of Alzheimer's disease. Cochrane Database Syst Rev 2007;3, DOI: An interesting review indicating that there is a lack of evidence as to whether clioquinol has any positive clinical benefit in patients with AD.
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(2007)
Cochrane Database Syst Rev
, vol.3
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Sampson, E.L.1
Jenagaratnam, L.2
McShane, R.3
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