The role of oxytocin in male and female reproductive behavior

European Journal of Pharmacology

Volumn 753, Issue , 2015, Pages 209-228

  Veening, J G ^a,c   De Jong, T R ^b   Waldinger, M D ^a   Korte, S M ^a   Olivier, B ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF REGENSBURG   (Germany)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Ejaculation; Maternal behavior; Oxytocin Reproductive behavior; Paternal behavior; Ventromedial hypothalamus

Indexed keywords

OXYTOCIN; SEROTONIN;

AGGRESSIVENESS; APPETITE; ARTICLE; COPULATION; EJACULATION; FEMALE; HORMONE BLOOD LEVEL; HORMONE SYNTHESIS; HUMAN; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; LORDOSIS; MALE; MATERNAL BEHAVIOR; NEUROTRANSMISSION; NONHUMAN; ORGASM; PATERNAL BEHAVIOR; PENIS ERECTION; PREMATURE EJACULATION; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; REPRODUCTIVE BEHAVIOR; SEX DIFFERENCE; ANIMAL; PHYSIOLOGY; SEXUAL BEHAVIOR;

ANIMALS; HUMANS; MATERNAL BEHAVIOR; OXYTOCIN; PATERNAL BEHAVIOR; REPRODUCTIVE BEHAVIOR; SEXUAL BEHAVIOR, ANIMAL; VENTROMEDIAL HYPOTHALAMIC NUCLEUS;

EID: 84925424023     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.07.045     Document Type: Article

References (515)

1. A.E. Ackerman, G.M. Lange, and L.G. Clemens Effects of paraventricular lesions on sex behavior and seminal emission in male rats Physiol. Behav. 63 1997 49 53
2. D. Agrati, A. Fernandez-Guasti, M. Ferreno, and A. Ferreira Coexpression of sexual behavior and maternal aggression: the ambivalence of sexually active mother rats toward male intruders Behav. Neurosci. 125 2011 446 451
3. S. Ahlenius, and K. Larsson Synergistic actions of the 5-HT1A receptor antagonist WAY-100635 and citalopram on male rat ejaculatory behavior Eur. J. Pharmacol. 379 1999 1 6
4. S. Ahlenius, K. Larsson, L. Svensson, S. Hjorth, A. Carlsson, P. Lindberg, H. Wikstrom, D. Sanchez, L.E. Arvidsson, U. Hacksell, and J.L. Nilsson Effects of a new type of 5-HT receptor agonist on male rat sexual behavior Pharmacol.; Biochem. Behav. 15 1981 785 792
5. S. Akther, N. Korshnova, J. Zhong, M. Liang, S.M. Cherepanov, O. Lopatina, Y.K. Komleva, A.B. Salmina, T. Nishimura, A.A. Fakhrul, H. Hirai, I. Kato, Y. Yamamoto, S. Takasawa, H. Okamoto, and H. Higashida CD38 in the nucleus accumbens and oxytocin are related to paternal behavior in mice Mol. Brain 6 2013 41
6. D.J. Albert, R.H. Jonik, and M.L. Walsh Hormone-dependent aggression in male and female rats: experiential, hormonal, and neural foundations Neurosci. Biobehav. Rev. 16 1992 177 192
7. D.J. Albert, R.H. Jonik, and M.L. Walsh Interaction of estradiol, testosterone, and progesterone in the modulation of hormone-dependent aggression in the female rat Physiol. Behav. 52 1992 773 779
8. D.J. Albert, R.H. Jonik, and M.L. Walsh Ovariectomy does not attenuate aggression by primiparous lactating female rats Physiol. Behav. 52 1992 1043 1046
9. G.A. Alvares, I.B. Hickie, and A.J. Guastella Acute effects of intranasal oxytocin on subjective and behavioral responses to social rejection Exp. Clin. Psychopharmacol. 18 2010 316 321
10. D.J. Anderson Optogenetics, sex, and violence in the brain: implications for psychiatry Biol. Psychiatry 71 2012 1081 1089
11. G.W. Arendash, and R.A. Gorski Suppression of lordotic responsiveness in the female rat during mesencephalic electrical stimulation Pharmacol.; Biochem. Behav. 19 1983 351 357
12. A. Argiolas, M. Collu, P. D'Aquila, G.L. Gessa, M.R. Melis, and G. Serra Apomorphine stimulation of male copulatory behavior is prevented by the oxytocin antagonist d(CH2)5 Tyr(Me)-Orn8-vasotocin in rats Pharmacol.; Biochem. Behav. 33 1989 81 83
13. A. Argiolas, M. Collu, G.L. Gessa, M.R. Melis, and G. Serra The oxytocin antagonist d(CH2)5 Tyr(Me)-Orn8-vasotocin inhibits male copulatory behaviour in rats Eur. J. Pharmacol. 149 1988 389 392
14. A. Argiolas, and M.R. Melis Neuropeptides and central control of sexual behaviour from the past to the present: a review Prog. Neurobiol. 108 2013 80 107
15. A. Argiolas, M.R. Melis, and G.L. Gessa Intraventricular oxytocin induces yawning and penile erection in rats Eur. J. Pharmacol. 117 1985 395 396
16. A. Argiolas, M.R. Melis, R. Stancampiano, and G.L. Gessa Penile erection and yawning induced by oxytocin and related peptides: structure-activity relationship Peptides 10 1989 559 563
17. R. Arletti, C. Bazzani, M. Castelli, and A. Bertolini Oxytocin improves male copulatory performance in rats Horm. Behav. 19 1985 14 20
18. R. Arletti, A. Benelli, and A. Bertolini Influence of oxytocin on feeding behavior in the rat Peptides 10 1989 89 93
19. R. Arletti, A. Benelli, and A. Bertolini Sexual behavior of aging male rats is stimulated by oxytocin Eur. J. Pharmacol. 179 1990 377 381
20. R. Arletti, A. Benelli, and A. Bertolini Oxytocin involvement in male and female sexual behavior Ann. N. Y. Acad. Sci. 652 1992 180 193
21. R. Arletti, and A. Bertolini Oxytocin stimulates lordosis behavior in female rats Neuropeptides 6 1985 247 253
22. R. Arletti, L. Calza, L. Giardino, A. Benelli, E. Cavazzuti, and A. Bertolini Sexual impotence is associated with a reduced production of oxytocin and with an increased production of opioid peptides in the paraventricular nucleus of male rats Neurosci. Lett. 233 1997 65 68
23. W.E. Armstrong The neurophysiology of neurosecretory cells J. Physiol. 585 2007 645 647
24. W.E. Armstrong, and G.I. Hatton The localization of projection neurons in the rat hypothalamic paraventricular nucleus following vascular and neurohypophysial injections of HRP Brain Res. Bull. 5 1980 473 477
25. W.E. Armstrong, and G.I. Hatton The puzzle of pulsatile oxytocin secretion during lactation: some new pieces Am. J. Physiol. Regul.; Integr. Comp. Physiol. 291 2006 R26 R28
26. W.E. Armstrong, S. Warach, G.I. Hatton, and T.H. McNeill Subnuclei in the rat hypothalamic paraventricular nucleus: a cytoarchitectural, horseradish peroxidase and immunocytochemical analysis Neuroscience 5 1980 1931 1958
27. D. Atasoy, J.N. Betley, H.H. Su, and S.M. Sternson Deconstruction of a neural circuit for hunger Nature 488 2012 172 177
28. T.L. Bale, and D.M. Dorsa Sex differences in and effects of estrogen on oxytocin receptor messenger ribonucleic acid expression in the ventromedial hypothalamus Endocrinology 136 1995 27 32
29. K.L. Bales, A.J. Kim, A.D. Lewis-Reese, and C. Sue Carter Both oxytocin and vasopressin may influence alloparental behavior in male prairie voles Horm. Behav. 45 2004 354 361
30. M. Bancila, F. Giuliano, O. Rampin, P. Mailly, M.J. Brisorgueil, A. Calas, and D. Verge Evidence for a direct projection from the paraventricular nucleus of the hypothalamus to putative serotoninergic neurons of the nucleus paragigantocellularis involved in the control of erection in rats Eur. J. Neurosci. 16 2002 1240 1248
31. J. Bancroft The endocrinology of sexual arousal J. Endocrinol. 186 2005 411 427
32. W. Bargmann Über die Neurosekretorische Verknüpfung von Hypothalamus und Neurohypophyse Z. Zellforsch. mikrosk. Anat. 34 1949 610 634
33. T.A. Baskerville, and A.J. Douglas Dopamine and oxytocin interactions underlying behaviors: potential contributions to behavioral disorders CNS Neurosci. Ther. 16 2010 e92 123
34. T. Baumgartner, M. Heinrichs, A. Vonlanthen, U. Fischbacher, and E. Fehr Oxytocin shapes the neural circuitry of trust and trust adaptation in humans Neuron 58 2008 639 650
35. S.L. Bealer, W.E. Armstrong, and W.R. Crowley Oxytocin release in magnocellular nuclei: neurochemical mediators and functional significance during gestation Am. J. Physiol. Regul.; Integr. Comp. Physiol. 299 2010 R452 R458
36. B. Behnia, M. Heinrichs, W. Bergmann, S. Jung, J. Germann, M. Schedlowski, U. Hartmann, and T.H. Kruger Differential effects of intranasal oxytocin on sexual experiences and partner interactions in couples Horm. Behav. 65 2014 308 318
37. D.I. Beiderbeck, I.D. Neumann, and A.H. Veenema Differences in intermale aggression are accompanied by opposite vasopressin release patterns within the septum in rats bred for low and high anxiety Eur. J. Neurosci. 26 2007 3597 3605
38. M.C. Beinfeld An introduction to neuronal cholecystokinin Peptides 22 2001 1197 1200
39. A.L. Bennett, B. Greco, M.E. Blasberg, and J.D. Blaustein Response to male odours in progestin receptor- and oestrogen receptor-containing cells in female rat brain J. Neuroendocrinol. 14 2002 442 449
40. C.V. Bishop Progesterone inhibition of oxytocin signaling in endometrium Front. Neurosci. 7 2013 138
41. E. Bjorkstrand, S. Ahlenius, U. Smedh, and K. Uvnas-Moberg The oxytocin receptor antagonist 1-deamino-2-D-Tyr-(OEt)-4-Thr-8-Orn-oxytocin inhibits effects of the 5-HT1A receptor agonist 8-OH-DPAT on plasma levels of insulin, cholecystokinin and somatostatin Regul. Pept. 63 1996 47 52
42. W. Blaicher, D. Gruber, C. Bieglmayer, A.M. Blaicher, W. Knogler, and J.C. Huber The role of oxytocin in relation to female sexual arousal Gynecol. Obstet. Investig. 47 1999 125 126
43. J.D. Blaustein, M.J. Tetel, K.H. Ricciardi, Y. Delville, and J.C. Turcotte Hypothalamic ovarian steroid hormone-sensitive neurons involved in female sexual behavior Psychoneuroendocrinology 19 1994 505 516
44. J.E. Blevins, T.J. Eakin, J.A. Murphy, M.W. Schwartz, and D.G. Baskin Oxytocin innervation of caudal brainstem nuclei activated by cholecystokinin Brain Res. 993 2003 30 41
45. J.E. Blevins, and J.M. Ho Role of oxytocin signaling in the regulation of body weight Rev. Endocr. Metab. Disord. 14 2013 311 329
46. J.E. Blevins, M.W. Schwartz, and D.G. Baskin Evidence that paraventricular nucleus oxytocin neurons link hypothalamic leptin action to caudal brain stem nuclei controlling meal size Am. J. Physiol. Regul. Integr. Comp. Physiol. 287 2004 R87 R96
47. M.L. Boccia, A.P. Goursaud, J. Bachevalier, K.D. Anderson, and C.A. Pedersen Peripherally administered non-peptide oxytocin antagonist, L368,899, accumulates in limbic brain areas: a new pharmacological tool for the study of social motivation in non-human primates Horm. Behav. 52 2007 344 351
48. C. Booth, C.P. Wayman, and V.M. Jackson An ex vivo multi-electrode approach to evaluate endogenous hormones and receptor subtype pharmacology on evoked and spontaneous neuronal activity within the ventromedial hypothalamus; translation from female receptivity J. Sex. Med. 7 2010 2411 2423
49. A.P. Borrow, and N.M. Cameron The role of oxytocin in mating and pregnancy Horm. Behav. 61 2012 266 276
50. O.J. Bosch, S.L. Meddle, D.I. Beiderbeck, A.J. Douglas, and I.D. Neumann Brain oxytocin correlates with maternal aggression: link to anxiety J. Neurosci.: Off. J. Soc. Neurosci. 25 2005 6807 6815
51. O.J. Bosch, and I.D. Neumann Both oxytocin and vasopressin are mediators of maternal care and aggression in rodents: from central release to sites of action Horm. Behav. 61 2012 293 303
52. E. Breslow, and S. Burman Molecular, thermodynamic, and biological aspects of recognition and function in neurophysin-hormone systems: a model system for the analysis of protein-peptide interactions Adv. Enzymol. Relat. Areas Mol. Biol. 63 1990 1 67
53. R.S. Brogan, K.L. Grove, and M.S. Smith Differential regulation of leptin receptor but not orexin in the hypothalamus of the lactating rat J. Neuroendocrinol. 12 2000 1077 1086
54. C.H. Brown, J.S. Bains, M. Ludwig, and J.E. Stern Physiological regulation of magnocellular neurosecretory cell activity: integration of intrinsic, local and afferent mechanisms J. Neuroendocrinol. 25 2013 678 710
55. J. Bueno, and D.W. Pfaff Single unit recording in hypothalamus and preoptic area of estrogen-treated and untreated ovariectomized female rats Brain Res. 101 1976 67 78
56. R.M. Buijs Intra- and extrahypothalamic vasopressin and oxytocin pathways in the rat. Pathways to the limbic system, medulla oblongata and spinal cord Cell Tissue Res. 192 1978 423 435
57. R.M. Buijs Intra- and extrahypothalamic vasopressin and oxytocin pathways in the rat. Pathways to the limbic system, medulla oblongata and spinal cord Cell Tissue Res. 192 1978 423 435
58. R.M. Buijs, G.J. De Vries, F.W. Van Leeuwen, and D.F. Swaab Vasopressin and oxytocin: distribution and putative functions in the brain Prog. Brain Res. 60 1983 115 122
59. R.M. Buijs, D.F. Swaab, J. Dogterom, and F.W. van Leeuwen Intra- and extrahypothalamic vasopressin and oxytocin pathways in the rat Cell Tissue Res. 186 1978 423 433
60. P. Buma Characterization of luteinizing hormone-releasing hormone fibres in the mesencephalic central grey substance of the rat Neuroendocrinology 49 1989 623 630
61. F. Calcagnoli, S.F. de Boer, M. Althaus, J.A. den Boer, and J.M Koolhaas Antiaggressive activity of central oxytocin in male rats Psychopharmacology (Berl) 229 2013 639 651
62. J.D. Caldwell Central oxytocin and female sexual behavior Ann. N. Y. Acad. Sci. 652 1992 166 179
63. J.D. Caldwell A sexual arousability model involving steroid effects at the plasma membrane Neurosci. Biobehav. Rev. 26 2002 13 30
64. J.D. Caldwell, G.F. Jirikowski, E.R. Greer, and C.A. Pedersen Medial preoptic area oxytocin and female sexual receptivity Behav. Neurosci. 103 1989 655 662
65. J.D. Caldwell, G.F. Jirikowski, E.R. Greer, W.E. Stumpf, and C.A. Pedersen Ovarian steroids and sexual interaction alter oxytocinergic content and distribution in the basal forebrain Brain Res. 446 1988 236 244
66. J.D. Caldwell, J.M. Johns, B.M. Faggin, M.A. Senger, and C.A. Pedersen Infusion of an oxytocin antagonist into the medial preoptic area prior to progesterone inhibits sexual receptivity and increases rejection in female rats Horm. Behav. 28 1994 288 302
67. J.D. Caldwell, A.J. Prange Jr.; and C.A. Pedersen Oxytocin facilitates the sexual receptivity of estrogen-treated female rats Neuropeptides 7 1986 175 189
68. L.H. Calizo, and L.M. Flanagan-Cato Estrogen-induced dendritic spine elimination on female rat ventromedial hypothalamic neurons that project to the periaqueductal gray J. Comp. Neurol. 447 2002 234 248
69. L.H. Calizo, and L.M. Flanagan-Cato Hormonal-neural integration in the female rat ventromedial hypothalamus: triple labeling for estrogen receptor-alpha, retrograde tract tracing from the periaqueductal gray, and mating-induced Fos expression Endocrinology 144 2003 5430 5440
70. N. Cameron, and M.S. Erskine c-FOS expression in the forebrain after mating in the female rat is altered by adrenalectomy Neuroendocrinology 77 2003 305 313
71. N.M. Cameron, E. Soehngen, and M.J. Meaney Variation in maternal care influences ventromedial hypothalamus activation in the rat J. Neuroendocrinol. 23 2011 393 400
72. N.S. Canteras The medial hypothalamic defensive system: hodological organization and functional implications Pharmacol.; Biochem. Behav. 71 2002 481 491
73. N.S. Canteras, R.B. Simerly, and L.W. Swanson Organization of projections from the ventromedial nucleus of the hypothalamus: a Phaseolus vulgaris-leucoagglutinin study in the rat J. Comp. Neurol. 348 1994 41 79
74. C. Caquineau, G. Leng, X.M. Guan, M. Jiang, L. Van der Ploeg, and A.J. Douglas Effects of alpha-melanocyte-stimulating hormone on magnocellular oxytocin neurones and their activation at intromission in male rats J. Neuroendocrinol. 18 2006 685 691
75. M.S. Carmichael, R. Humbert, J. Dixen, G. Palmisano, W. Greenleaf, and J.M. Davidson Plasma oxytocin increases in the human sexual response J. Clin. Endocrinol. Metab. 64 1987 27 31
76. M.S. Carmichael, V.L. Warburton, J. Dixen, and J.M. Davidson Relationships among cardiovascular, muscular, and oxytocin responses during human sexual activity Arch. Sexual Behav. 23 1994 59 79
77. H.F. Carrer, and A. Aoki Ultrastructural changes in the hypothalamic ventromedial nucleus of ovariectomized rats after estrogen treatment Brain Res. 240 1982 221 233
78. M. Carro-Juarez, and G. Rodriguez-Manzo Evidence for the presence and functioning of the spinal generator for ejaculation in the neonatal male rat Int. J. Impot. Res. 17 2005 270 276
79. C.S. Carter Oxytocin and sexual behavior Neurosci. Biobehav. Rev. 16 1992 131 144
80. C.S. Carter Neuroendocrine perspectives on social attachment and love Psychoneuroendocrinology 23 1998 779 818
81. C.S. Carter Oxytocin pathways and the evolution of human behavior Annu. Rev. Psychol. 65 2014 17 39
82. C.S. Carter, A.C. DeVries, and L.L. Getz Physiological substrates of mammalian monogamy: the prairie vole model Neurosci. Biobehav. Rev. 19 1995 303 314
83. C.S. Carter, and S.W. Porges The biochemistry of love: an oxytocin hypothesis EMBO Rep. 14 2013 12 16
84. S.J. Carter, C.M. Richardson, and J.B. Wakerley Excitatory effects of oxytocin and cholecystokinin on oxytocin neurones: differences between virgin, pregnant and lactating rats Neurosci. Lett. 351 2003 13 16
85. F.A Champagne Epigenetic mechanisms and the transgenerational effects of maternal care Front. Neuroendocrinol. 29 2008 386 397
86. V.E. Chaves, C.Q. Tilelli, N.A. Brito, and M.N. Brito Role of oxytocin in energy metabolism Peptides 45 2013 9 14
87. K. Chen, and L.S. Chang Oxytocinergic neurotransmission at the hippocampus in the central neural regulation of penile erection in the rat Urology 58 2001 107 112
88. M.M. Cho, A.C. DeVries, J.R. Williams, and C.S. Carter The effects of oxytocin and vasopressin on partner preferences in male and female prairie voles (Microtus ochrogaster) Behav. Neurosci. 113 1999 1071 1079
89. S.K. Chung, D.W. Pfaff, and R.S. Cohen Projections of ventromedial hypothalamic neurons to the midbrain central gray: an ultrastructural study Neuroscience 38 1990 395 407
90. P.S. Churchland, and P. Winkielman Modulating social behavior with oxytocin: how does it work? What does it mean? Horm. Behav. 61 2012 392 399
91. P. Clement, J. Bernabe, S. Compagnie, L. Alexandre, S. McCallum, and F. Giuliano Inhibition of ejaculation by the non-peptide oxytocin receptor antagonist GSK557296: a multi-level site of action Br. J. Pharmacol. 169 2013 1477 1485
92. P. Clement, M. Peeters, J. Bernabe, P. Denys, L. Alexandre, and F. Giuliano Brain oxytocin receptors mediate ejaculation elicited by 7-hydroxy-2-(di-N-propylamino) tetralin (7-OH-DPAT) in anaesthetized rats Br. J. Pharmacol. 154 2008 1150 1159
93. H. Coirini, A.E. Johnson, and B.S. McEwen Estradiol modulation of oxytocin binding in the ventromedial hypothalamic nucleus of male and female rats Neuroendocrinology 50 1989 193 198
94. A.R. Consiglio, and A.B. Lucion Lesion of hypothalamic paraventricular nucleus and maternal aggressive behavior in female rats Physiol. Behav. 59 1996 591 596
95. L.M. Coolen, B. Olivier, H.J. Peters, and J.G. Veening Demonstration of ejaculation-induced neural activity in the male rat brain using 5-HT1A agonist 8-OH-DPAT Physiol. Behav. 62 1997 881 891
96. L.M. Coolen, H.J. Peters, and J.G. Veening Fos immunoreactivity in the rat brain following consummatory elements of sexual behavior: a sex comparison Brain Res. 738 1996 67 82
97. G.A. Coria-Avila, and J.G. Pfaus Neuronal activation by stimuli that predict sexual reward in female rats Neuroscience 148 2007 623 632
98. G. Corona, E.A. Jannini, L. Vignozzi, G. Rastrelli, and M. Maggi The hormonal control of ejaculation Nat. Rev. Urol. 9 2012 508 519
99. C. Crockford, R.M. Wittig, K. Langergraber, T.E. Ziegler, K. Zuberbuhler, and T. Deschner Urinary oxytocin and social bonding in related and unrelated wild chimpanzees Proc. Biol. Sci./R. Soc. 280 2013 20122765
100. W.R. Crowley, S.L. Parker, W.E. Armstrong, L.H. Spinolo, and C.E. Grosvenor Neurotransmitter and neurohormonal regulation of oxytocin secretion in lactation Ann. N. Y. Acad. Sci. 652 1992 286 302
101. D. Daniels, and L.M. Flanagan-Cato Functionally-defined compartments of the lordosis neural circuit in the ventromedial hypothalamus in female rats J. Neurobiol. 45 2000 1 13
102. D. Daniels, R.R. Miselis, and L.M. Flanagan-Cato Central neuronal circuit innervating the lordosis-producing muscles defined by transneuronal transport of pseudorabies virus J. Neurosci.: Off. J. Soc. Neurosci. 19 1999 2823 2833
103. P.G. Davis, B.S. McEwen, and D.W. Pfaff Localized behavioral effects of tritiated estradiol implants in the ventromedial hypothalamus of female rats Endocrinology 104 1979 898 903
104. T.R. de Jong, M. Chauke, B.N. Harris, and W. Saltzman From here to paternity: neural correlates of the onset of paternal behavior in California mice (Peromyscus californicus) Horm. Behav. 56 2009 220 231
105. T.R. de Jong, T. Pattij, J.G. Veening, P.J. Dederen, M.D. Waldinger, A.R. Cools, and B. Olivier Citalopram combined with WAY 100635 inhibits ejaculation and ejaculation-related Fos immunoreactivity Eur. J. Pharmacol. 509 2005 49 59
106. T.R. de Jong, T. Pattij, J.G. Veening, P.J. Dederen, M.D. Waldinger, A.R. Cools, and B. Olivier Effects of chronic paroxetine pretreatment on (+/-)-8-hydroxy-2-(di-n-propyl-amino)tetralin induced c-fos expression following sexual behavior Neuroscience 134 2005 1351 1361
107. T.R. de Jong, T. Pattij, J.G. Veening, M.D. Waldinger, A.R. Cools, and B. Olivier Effects of chronic selective serotonin reuptake inhibitors on 8-OH-DPAT-induced facilitation of ejaculation in rats: comparison of fluvoxamine and paroxetine Psychopharmacology 179 2005 509 515
108. T.R. de Jong, L.J. Snaphaan, T. Pattij, J.G. Veening, M.D. Waldinger, A.R. Cools, and B. Olivier Effects of chronic treatment with fluvoxamine and paroxetine during adolescence on serotonin-related behavior in adult male rats Eur. Neuropsychopharmacol.: J. Eur. Coll. Neuropsychopharmacol. 16 2006 39 48
109. T.R. de Jong, J.G. Veening, B. Olivier, and M.D. Waldinger Oxytocin involvement in SSRI-induced delayed ejaculation: a review of animal studies J. Sex. Med. 4 2007 14 28
110. N. Deblon, C. Veyrat-Durebex, L. Bourgoin, A. Caillon, A.L. Bussier, S. Petrosino, F. Piscitelli, J.J. Legros, V. Geenen, M. Foti, W. Wahli, V. Di Marzo, and F. Rohner-Jeanrenaud Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats PloS One 6 2011 e25565
111. J.F. DeBold, and C.W. Malsbury Facilitation of sexual receptivity by hypothalamic and midbrain implants of progesterone in female hamsters Physiol. Behav. 46 1989 655 660
112. T.L. Dellovade, J. Chan, B. Vennstrom, D. Forrest, and D.W. Pfaff The two thyroid hormone receptor genes have opposite effects on estrogen-stimulated sex behaviors Nat. Neurosci. 3 2000 472 475
113. M.A. Demitrack, M.D. Lesem, H.A. Brandt, T.A. Pigott, D.C. Jimerson, M. Altemus, and P.W. Gold Neurohypophyseal dysfunction: implications for the pathophysiology of eating disorders Psychopharmacol. Bull. 25 1989 439 443
114. D. Devost, P. Wrzal, and H.H. Zingg Oxytocin receptor signalling Prog. Brain Res. 170 2008 167 176
115. A.C. DeVries, W.S. Young 3rd, and R.J. Nelson Reduced aggressive behaviour in mice with targeted disruption of the oxytocin gene J. Neuroendocrinol. 9 1997 363 368
116. M.B. Dhakar, M.E. Rich, E.L. Reno, H.J. Lee, and H.K. Caldwell Heightened aggressive behavior in mice with lifelong versus postweaning knockout of the oxytocin receptor Horm. Behav. 62 2012 86 92
117. D.R. Diaz, D.E. Fleming, and R.W. Rhees The hormone-sensitive early postnatal periods for sexual differentiation of feminine behavior and luteinizing hormone secretion in male and female rats. Brain research Dev. Brain Res. 86 1995 227 232
118. G.P. Dohanich, and I.L. Ward Sexual behavior in male rats following intracerebral estrogen application J. Com. Physiol. Psychol. 94 1980 634 640
119. J.M. Dominguez, and E.M. Hull Serotonin impairs copulation and attenuates ejaculation-induced glutamate activity in the medial preoptic area Behav. Neurosci. 124 2010 554 557
120. N. Donner, and I.D. Neumann Effects of chronic intracerebral prolactin on the oxytocinergic and vasopressinergic system of virgin ovariectomized rats Neuroendocrinology 90 2009 315 322
121. A.J. Douglas, L.E. Johnstone, and G. Leng Neuroendocrine mechanisms of change in food intake during pregnancy: a potential role for brain oxytocin Physiol. Behav. 91 2007 352 365
122. V. Du Vigneaud, C. Ressler, and S. Trippett The sequence of amino acids in oxytocin, with a proposal for the structure of oxytocin J. Biol. Chem. 205 1953 949 957
123. B.N. Dugger, J.A. Morris, C.L. Jordan, and S.M. Breedlove Androgen receptors are required for full masculinization of the ventromedial hypothalamus (VMH) in rats Horm. Behav. 51 2007 195 201
124. M. Egli, B. Leeners, and T.H. Kruger Prolactin secretion patterns: basic mechanisms and clinical implications for reproduction Reproduction 140 2010 643 654
125. D.E. Emery Effects of endocrine state on sociosexual behavior of female rats tested in a complex environment Behav. Neurosci. 100 1986 71 78
126. M. Eriksson, E. Bjorkstrand, U. Smedh, P. Alster, A.S. Matthiesen, and K. Uvnas-Moberg Role of vagal nerve activity during suckling. Effects on plasma levels of oxytocin, prolactin, VIP, somatostatin, insulin, glucagon, glucose and of milk secretion in lactating rats Acta Physiol. Scand. 151 1994 453 459
127. M.S. Erskine, V.H. Denenberg, and B.D. Goldman Aggression in the lactating rat: effects of intruder age and test arena Behav. Biol. 23 1978 52 66
128. S.E. Fahrbach, J.I. Morrell, and D.W. Pfaff Studies of ventromedial hypothalamic afferents in the rat using three methods of HRP application Exp. Brain Res. Exp. Hirnforsch. Exp. Cereb. 77 1989 221 233
129. R. Feldman, I. Gordon, and O. Zagoory-Sharon Maternal and paternal plasma, salivary, and urinary oxytocin and parent-infant synchrony: considering stress and affiliation components of human bonding Dev. Sci. 14 2011 752 761
130. R. Feldman, O. Zagoory-Sharon, O. Weisman, I. Schneiderman, I. Gordon, R. Maoz, I. Shalev, and R.P. Ebstein Sensitive parenting is associated with plasma oxytocin and polymorphisms in the OXTR and CD38 genes Biol. Psychiatry 72 2012 175 181
131. A. Ferreira, M. Pereira, D. Agrati, N. Uriarte, and A. Fernandez-Guasti Role of maternal behavior on aggression, fear and anxiety Physiol. Behav. 77 2002 197 204
132. S.L. Ferri, and L.M. Flanagan-Cato Oxytocin and dendrite remodeling in the hypothalamus Horm. Behav. 61 2012 251 258
133. C.F. Ferris, K.B. Foote, H.M. Meltser, M.G. Plenby, K.L. Smith, and T.R. Insel Oxytocin in the amygdala facilitates maternal aggression Ann. N. Y. Acad. Sci. 652 1992 456 457
134. L.M. Flanagan, J.G. Pfaus, D.W. Pfaff, and B.S. McEwen Induction of FOS immunoreactivity in oxytocin neurons after sexual activity in female rats Neuroendocrinology 58 1993 352 358
135. L.M. Flanagan-Cato Sex differences in the neural circuit that mediates female sexual receptivity Front. Neuroendocrinol. 32 2011 124 136
136. L.M. Flanagan-Cato, L.H. Calizo, and D. Daniels The synaptic organization of VMH neurons that mediate the effects of estrogen on sexual behavior Horm. Behav. 40 2001 178 182
137. L.M. Flanagan-Cato, B.J. Lee, and L.H. Calizo Co-localization of midbrain projections, progestin receptors, and mating-induced fos in the hypothalamic ventromedial nucleus of the female rat Horm. Behav. 50 2006 52 60
138. L.M. Flanagan-Cato, and B.S. McEwen Pattern of Fos and Jun expression in the female rat forebrain after sexual behavior Brain Res. 673 1995 53 60
139. A.S. Fleming Control of food intake in the lactating rat: role of suckling and hormones Physiol. Behav. 17 1976 841 848
140. A.S. Fleming, and J.S. Rosenblatt Olfactory regulation of maternal behavior in rats. I. Effects of olfactory bulb removal in experienced and inexperienced lactating and cycling females J. Comp. Physiol. Psychol. 86 1974 221 232
141. A.S. Fleming, and J.S. Rosenblatt Olfactory regulation of maternal behavior in rats. II. Effects of peripherally induced anosmia and lesions of the lateral olfactory tract in pup-induced virgins J. Comp. Physiol. Psychol. 86 1974 233 246
142. O.R. Floody, and J.F. DeBold Effects of midbrain lesions on lordosis and ultrasound production Physiol. Behav. 82 2004 791 804
143. M. Frankfurt, E. Gould, C.S. Woolley, and B.S. McEwen Gonadal steroids modify dendritic spine density in ventromedial hypothalamic neurons: a Golgi study in the adult rat Neuroendocrinology 51 1990 530 535
144. M. Frankfurt, and B.S. McEwen 5,7-Dihydroxytryptamine and gonadal steroid manipulation alter spine density in ventromedial hypothalamic neurons Neuroendocrinology 54 1991 653 657
145. M.E. Freeman, and J.A. Banks Hypothalamic sites which control the surges of prolactin secretion induced by cervical stimulation Endocrinology 106 1980 668 673
146. K.S. Frohmader, K.K. Pitchers, M.E. Balfour, and L.M Coolen Mixing pleasures: review of the effects of drugs on sex behavior in humans and animal models Horm. Behav. 58 2010 149 162
147. A. Fukushima, P. Yin, M. Ishida, N. Sugiyama, and J. Arita Pup removal suppresses estrogen-induced surges of LH secretion and activation of GnRH neurons in lactating rats J. Endocrinol. 191 2006 339 348
148. R. Gandelman, and N.G. Simon Postpartum fighting in the rat: nipple development and the presence of young Behav. Neural Biol. 28 1980 350 360
149. E.K. Gee, L. Gillespie, and C.F. Bolwell Effect of oxytocin on suppression of oestrus in mares exhibiting normal oestrous cycles N. Z. Vet. J. 60 2012 189 193
150. L.M. Geeraedts, R. Nieuwenhuys, and J.G. Veening Medial forebrain bundle of the rat: III. Cytoarchitecture of the rostral (telencephalic) part of the medial forebrain bundle bed nucleus J. Comp. Neurol. 294 1990 507 536
151. L.M. Geeraedts, R. Nieuwenhuys, and J.G. Veening Medial forebrain bundle of the rat: IV. Cytoarchitecture of the caudal (lateral hypothalamic) part of the medial forebrain bundle bed nucleus J. Comp. Neurol. 294 1990 537 568
152. H. Gelez, S. Poirier, P. Facchinetti, K.A. Allers, C. Wayman, L. Alexandre, and F. Giuliano Neuroanatomical evidence for a role of central melanocortin-4 receptors and oxytocin in the efferent control of the rodent clitoris and vagina J. Sex. Med. 7 2010 2056 2067
153. M. Georgescu, and J.G. Pfaus Role of glutamate receptors in the ventromedial hypothalamus in the regulation of female rat sexual behaviors I. Behavioral effects of glutamate and its selective receptor agonists AMPA, NMDA and kainate Pharmacol.; Biochem. Behav. 83 2006 322 332
154. M. Georgescu, and J.G. Pfaus Role of glutamate receptors in the ventromedial hypothalamus in the regulation of female rat sexual behaviors. II. Behavioral effects of selective glutamate receptor antagonists AP-5, CNQX, and DNQX. Pharmacol.; Biochem. Behav. 83 2006 333 341
155. M. Georgescu, C. Sabongui, A. Del Corpo, L. Marsan, and J.G. Pfaus Vaginocervical stimulation induces Fos in glutamate neurons in the ventromedial hypothalamus: attenuation by estrogen and progesterone Horm. Behav. 56 2009 450 456
156. I. Gerendai, I.E. Toth, K. Kocsis, Z. Boldogkoi, M. Rusvai, and B. Halasz Identification of CNS neurons involved in the innervation of the epididymis: a viral transneuronal tracing study Auton. Neurosci.: Basic Clin. 92 2001 1 10
157. P.O. Gerrits, M. Krukerink, and J.G. Veening Columnar organization of estrogen receptor-alpha immunoreactive neurons in the periaqueductal gray projecting to the nucleus para-retroambiguus in the caudal brainstem of the female golden hamster Neuroscience 161 2009 459 474
158. R. Ghosh, and C.D. Sladek Role of prolactin and gonadal steroids in regulation of oxytocin mRNA during lactation Am. J. Physiol. 269 1995 E76 E84
159. S. Ghosh, S.D. Larson, H. Hefzi, Z. Marnoy, T. Cutforth, K. Dokka, and K.K. Baldwin Sensory maps in the olfactory cortex defined by long-range viral tracing of single neurons Nature 472 2011 217 220
160. M. Gil, R. Bhatt, K.B. Picotte, and E.M. Hull Oxytocin in the medial preoptic area facilitates male sexual behavior in the rat Horm. Behav. 59 2011 435 443
161. M. Gil, R. Bhatt, K.B. Picotte, and E.M. Hull Sexual experience increases oxytocin receptor gene expression and protein in the medial preoptic area of the male rat Psychoneuroendocrinology 38 2013 1688 1697
162. G. Gimpl, and F. Fahrenholz The oxytocin receptor system: structure, function, and regulation Physiol. Rev. 81 2001 629 683
163. M. Giovenardi, M.S. de Azevedo, S.P. da Silva, E. Hermel Edo, C.M. Gomes, and A.B Lucion Neonatal handling increases fear and aggression in lactating rats Physiol. Behav. 86 2005 209 217
164. M. Giovenardi, M.J. Padoin, L.P. Cadore, and A.B. Lucion Hypothalamic paraventricular nucleus, oxytocin, and maternal aggression in rats Ann. N. Y. Acad. Sci. 807 1997 606 609
165. A. Giraldi, L. Marson, R. Nappi, J. Pfaus, A.M. Traish, Y. Vardi, and I. Goldstein Physiology of female sexual function: animal models J. Sex. Med. 1 2004 237 253
166. A. Giraldi, A.H. Rellini, J. Pfaus, and E. Laan Female sexual arousal disorders J. Sex. Med. 10 2013 58 73
167. F. Giuliano, J. Bernabe, K. McKenna, F. Longueville, and O. Rampin Spinal proerectile effect of oxytocin in anesthetized rats Am. J. Physiol. Regul.; Integr. Comp. Physiol. 280 2001 R1870 R1877
168. F. Giuliano, and P. Clement Serotonin and premature ejaculation: from physiology to patient management Eur. Urol. 50 2006 454 466
169. B.A. Gladue, and L.G. Clemens Development of feminine sexual behavior in the rat: androgenic and temporal influences Physiol. Behav. 29 1982 263 267
170. I. Gordon, O. Zagoory-Sharon, J.F. Leckman, and R. Feldman Oxytocin and the development of parenting in humans Biol. Psychiatry 68 2010 377 382
171. J.H. Gordon, D.M. Nance, C.J. Wallis, and R.A. Gorski Effects of septal lesions and chronic estrogen treatment on dopamine, GABA and lordosis behavior in male rats Brain Res. Bull. 4 1979 85 89
172. B.B. Gorzalka, and G.L. Lester Oxytocin-induced facilitation of lordosis behaviour in rats is progesterone-dependent Neuropeptides 10 1987 55 65
173. D.R. Grattan The actions of prolactin in the brain during pregnancy and lactation Prog. Brain Res. 133 2001 153 171
174. G.D. Gray, P. Soderstein, D. Tallentire, and J.M. Davidson Effects of lesions in various structures of the suprachiasmatic-preoptic region on LH regulation and sexual behavior in female rats Neuroendocrinology 25 1978 174 191
175. K.M. Grewen, S.S. Girdler, J. Amico, and K.C Light Effects of partner support on resting oxytocin, cortisol, norepinephrine, and blood pressure before and after warm partner contact 67 2005 531 538 Psychosom. Med. 67 2005 531 538
176. G.D. Griffin, S.L. Ferri-Kolwicz, B.A. Reyes, E.J. Van Bockstaele, and L.M. Flanagan-Cato Ovarian hormone-induced reorganization of oxytocin-labeled dendrites and synapses lateral to the hypothalamic ventromedial nucleus in female rats J. Comp. Neurol. 518 2010 4531 4545
177. D.J. Gubernick, J.T. Winslow, P. Jensen, L. Jeanotte, and J. Bowen Oxytocin changes in males over the reproductive cycle in the monogamous, biparental California mouse, Peromyscus californicus Horm. Behav. 29 1995 59 73
178. J. Gupta, R. Russell, C. Wayman, D. Hurley, and V. Jackson Oxytocin-induced contractions within rat and rabbit ejaculatory tissues are mediated by vasopressin V1A receptors and not oxytocin receptors Br. J. Pharmacol. 155 2008 118 126
179. S. Hansen Medial hypothalamic involvement in maternal aggression of rats Behav. Neurosci. 103 1989 1035 1046
180. S. Hansen, and A. Ferreira Food intake, aggression, and fear behavior in the mother rat: control by neural systems concerned with milk ejection and maternal behavior Behav. Neurosci. 100 1986 64 70
181. E. Hard, and S. Hansen Reduced fearfulness in the lactating rat Physiol. Behav. 35 1985 641 643
182. R.E. Harlan, B.D. Shivers, and D.W. Pfaff Midbrain microinfusions of prolactin increase the estrogen-dependent behavior, lordosis Science 219 1983 1451 1453
183. A.C. Harmon, K.L. Huhman, T.O. Moore, and H.E. Albers Oxytocin inhibits aggression in female Syrian hamsters J. Neuroendocrinol. 14 2002 963 969
184. G.I. Hatton, and Y.F. Wang Neural mechanisms underlying the milk ejection burst and reflex Prog. Brain Res. 170 2008 155 166
185. S. Hayashi, and T. Orimo Sterility and delayed vaginal opening following electrolytic lesions placed neonatally in medial preoptic area in female rats Endocrinol. Jpn. 22 1975 409 413
186. C.H. Hendricks, and R.A. Gabel Use of intranasal oxytocin in obstetrics. 1. A laboratory evaluation Am. J. Obstet. Gynecol. 79 1960 780 788
187. A.C. Hennessey, L. Camak, F. Gordon, and D.A. Edwards Connections between the pontine central gray and the ventromedial hypothalamus are essential for lordosis in female rats Behav. Neurosci. 104 1990 477 488
188. J. Herbert Peptides in the limbic system: neurochemical codes for co-ordinated adaptive responses to behavioural and physiological demand Prog. Neurobiol. 41 1993 723 791
189. V. Hillegaart, P. Alster, K. Uvnas-Moberg, and S. Ahlenius Sexual motivation promotes oxytocin secretion in male rats Peptides 19 1998 39 45
190. K. Honda, and T. Higuchi Effects of unilateral electrolytic lesion of the dorsomedial nucleus of the hypothalamus on milk-ejection reflex in the rat J. Reprod. Dev. 56 2010 98 102
191. K. Honda, and T. Higuchi Electrical activities of neurones in the dorsomedial hypothalamic nucleus projecting to the supraoptic nucleus during milk-ejection reflex in the rat J. Reprod. Dev. 56 2010 336 340
192. K. Honda, M. Yanagimoto, H. Negoro, K. Narita, T. Murata, and T. Higuchi Excitation of oxytocin cells in the hypothalamic supraoptic nucleus by electrical stimulation of the dorsal penile nerve and tactile stimulation of the penis in the rat Brain Res. Bull. 48 1999 309 313
193. P.K. House, A. Vyas, and R. Sapolsky Predator cat odors activate sexual arousal pathways in brains of Toxoplasma gondii infected rats PloS One 6 2011 e23277
194. E. Hrabovszky, J. Halasz, W. Meelis, M.R. Kruk, Z. Liposits, and J. Haller Neurochemical characterization of hypothalamic neurons involved in attack behavior: glutamatergic dominance and co-expression of thyrotropin-releasing hormone in a subset of glutamatergic neurons Neuroscience 133 2005 657 666
195. A.M. Hughes, B.J. Everitt, S.L. Lightman, and K. Todd Oxytocin in the central nervous system and sexual behaviour in male rats Brain Res. 414 1987 133 137
196. E.M. Hull Sex, drugs and gluttony: how the brain controls motivated behaviors Physiol. Behav. 104 2011 173 177
197. E.M. Hull, J.W. Muschamp, and S. Sato Dopamine and serotonin: influences on male sexual behavior Physiol. Behav. 83 2004 291 307
198. P.J. Huntingford Intranasal use of synthetic oxytocin in management of breast-feeding Br. Med. J. 1 1961 709 711
199. T.R. Insel Oxytocin - a neuropeptide for affiliation: evidence from behavioral, receptor autoradiographic, and comparative studies Psychoneuroendocrinology 17 1992 3 35
200. T.R. Insel The challenge of translation in social neuroscience: a review of oxytocin, vasopressin, and affiliative behavior Neuron 65 2010 768 779
201. T.R. Insel, and L.E. Shapiro Oxytocin receptor distribution reflects social organization in monogamous and polygamous voles Proc. Natl. Acad. Sci. USA 89 1992 5981 5985
202. P. Jern, L. Westberg, A. Johansson, L. Jonsson, J. Corander, N.K. Sandnabba, and P. Santtila Are single nucleotide polymorphisms in the oxytocin and vasopressin 1A/1B receptor genes likely candidates for variation in ejaculatory function? BJU Int. 110 2012 E1173 E1180
203. C. Kalcheim, H. Szechtman, and Y. Koch Bisexual behavior in male rats treated neonatally with antibodies to luteinizing hormone-releasing hormone J. Comp. Physiol. Psychol. 95 1981 36 44
204. S.M. Kagerbauer, J. Martin, T. Schuster, M. Blobner, E.F. Kochs, and R. Landgraf Plasma oxytocin and vasopressin do not predict neuropeptide concentrations in human cerebrospinal fluid J Neuroendocrinol. 25 2013 668 673
205. N. Kang, M.J. Baum, and J.A. Cherry A direct main olfactory bulb projection to the 'vomeronasal' amygdala in female mice selectively responds to volatile pheromones from males Eur. J. Neurosci. 29 2009 624 634
206. N. Kang, M.J. Baum, and J.A. Cherry Different profiles of main and accessory olfactory bulb mitral/tufted cell projections revealed in mice using an anterograde tracer and a whole-mount, flattened cortex preparation Chem. Senses 36 2011 251 260
207. M. Kavaliers, A. Clipperton-Allen, C.L. Cragg, J.A. Gustafsson, K.S. Korach, L. Muglia, and E. Choleris Male risk taking, female odors, and the role of estrogen receptors Physiol. Behav. 107 2012 751 761
208. K.A. Keay, and R. Bandler Parallel circuits mediating distinct emotional coping reactions to different types of stress Neurosci. Biobehav. Rev. 25 2001 669 678
209. K.A. Keay, C.I. Clement, B. Owler, A. Depaulis, and R. Bandler Convergence of deep somatic and visceral nociceptive information onto a discrete ventrolateral midbrain periaqueductal gray region Neuroscience 61 1994 727 732
210. J. Kelly, and L.W. Swanson Additional forebrain regions projecting to the posterior pituitary: preoptic region, bed nucleus of the stria terminalis, and zona incerta Brain Res. 197 1980 1 9
211. K.M. Kendrick Oxytocin, motherhood and bonding Exp. Physiol. 85 Spec No 2000 111S 124S
212. K.M. Kendrick, A.P. Da Costa, K.D. Broad, S. Ohkura, R. Guevara, F. Levy, and E.B. Keverne Neural control of maternal behaviour and olfactory recognition of offspring Brain Res. Bull. 44 1997 383 395
213. K.M. Kendrick, C. Fabre-Nys, D. Blache, J.A. Goode, and K.D. Broad The role of oxytocin release in the mediobasal hypothalamus of the sheep in relation to female sexual receptivity J. Neuroendocrinol. 5 1993 13 21
214. K.M. Kendrick, E.B. Keverne, B.A. Baldwin, and D.F. Sharman Cerebrospinal fluid levels of acetylcholinesterase, monoamines and oxytocin during labour, parturition, vaginocervical stimulation, lamb separation and suckling in sheep Neuroendocrinology 44 1986 149 156
215. K.M. Kendrick, E.B. Keverne, M.R. Hinton, and J.A. Goode Cerebrospinal fluid and plasma concentrations of oxytocin and vasopressin during parturition and vaginocervical stimulation in the sheep Brain Res. Bull. 26 1991 803 807
216. W.M. Kenkel, J. Paredes, J.R. Yee, H. Pournajafi-Nazarloo, K.L. Bales, and C.S. Carter Neuroendocrine and behavioural responses to exposure to an infant in male prairie voles J. Neuroendocrinol. 24 2012 874 886
217. M.E. Kirkpatrick, and L. Merrill Effect of systemic blockade of alpha(1)-noradrenergic receptors on sex behavior and vaginal-cervical stimulation-induced Fos in female rats Pharmacol.; Biochem. Behav. 97 2011 486 493
218. I. Kita, Y. Yoshida, and S. Nishino An activation of parvocellular oxytocinergic neurons in the paraventricular nucleus in oxytocin-induced yawning and penile erection Neurosci. Res. 54 2006 269 275
219. S.M. Klampfl, I.D. Neumann, and O.J. Bosch Reduced brain corticotropin-releasing factor receptor activation is required for adequate maternal care and maternal aggression in lactating rats Eur. J. Neurosci. 38 2013 2742 2750
220. H.S. Knobloch, A. Charlet, L.C. Hoffmann, M. Eliava, S. Khrulev, A.H. Cetin, P. Osten, M.K. Schwarz, P.H. Seeburg, R. Stoop, and V. Grinevich Evoked axonal oxytocin release in the central amygdala attenuates fear response Neuron 73 2012 553 566
221. H.S. Knobloch, and V. Grinevich Evolution of oxytocin pathways in the brain of vertebrates Front. Behav. Neurosci. 8 2014 31
222. S.B. Koch, M. van Zuiden, L. Nawijn, J.L. Frijling, D.J. Veltman, and M. Olff Intranasal oxytocin as strategy for medication-enhanced psychotherapy of PTSD: salience processing and fear inhibition processes Psychoneuroendocrinology 40C 2014 242 256
223. J.M. Kolunie, and J.M. Stern Maternal aggression: disruption by perioral anesthesia in lactating Long-Evans rats (Rattus norvegicus) J. Comp. Psychol. 104 1990 352 360
224. B.R. Komisaruk, and G. Sansone Neural pathways mediating vaginal function: the vagus nerves and spinal cord oxytocin Scand. J. Psychol. 44 2003 241 250
225. B.R. Komisaruk, and B. Whipple Love as sensory stimulation: physiological consequences of its deprivation and expression Psychoneuroendocrinology 23 1998 927 944
226. B.R. Komisaruk, B. Whipple, A. Crawford, W.C. Liu, A. Kalnin, and K. Mosier Brain activation during vaginocervical self-stimulation and orgasm in women with complete spinal cord injury: fMRI evidence of mediation by the vagus nerves Brain Res. 1024 2004 77 88
227. Y. Kondo, T. Koizumi, Y. Arai, M. Kakeyama, and K. Yamanouchi Functional relationships between mesencephalic central gray and septum in regulating lordosis in female rats: effect of dual lesions Brain Res. Bull. 32 1993 635 638
228. Y. Kondo, A. Shinoda, K. Yamanouchi, and Y. Arai Role of septum and preoptic area in regulating masculine and feminine sexual behavior in male rats Horm. Behav. 24 1990 421 434
229. L.M. Kow, A.E. Johnson, S. Ogawa, and D.W. Pfaff Electrophysiological actions of oxytocin on hypothalamic neurons in vitro: neuropharmacological characterization and effects of ovarian steroids Neuroendocrinology 54 1991 526 535
230. L.M. Kow, and D.W. Pfaff Transmitter and peptide actions on hypothalamic neurons in vitro: implications for lordosis Brain Res. Bull. 20 1988 857 861
231. T.H. Kruger, P. Haake, D. Chereath, W. Knapp, O.E. Janssen, M.S. Exton, M. Schedlowski, and U. Hartmann Specificity of the neuroendocrine response to orgasm during sexual arousal in men J. Endocrinol. 177 2003 57 64
232. M.R. Kruk Ethology and pharmacology of hypothalamic aggression in the rat Neurosci. Biobehav. Rev. 15 1991 527 538
233. M.R. Kruk, C.E. Van der Laan, W. Meelis, R.E. Phillips, J. Mos, and A.M. Van der Poel Brain-stimulation induced agonistic behaviour: a novel paradigm in ethopharmacological aggression research Prog. Clin. Biol. Res. 167 1984 157 177
234. M.R. Kruk, C.E. Van der Laan, J. Mos, A.M. Van der Poel, W. Meelis, and B. Olivier Comparison of aggressive behaviour induced by electrical stimulation in the hypothalamus of male and female rats Prog. Brain Res. 61 1984 303 314
235. M.R. Kruk, and A.M. van der Poel Is there evidence for a neural correlate of an aggressive behavioural system in the hypothalamus of the rat? Prog. Brain Res. 53 1980 385 390
236. M.R. Kruk, A.M. van der Poel, and T.P. de Vos-Frerichs The induction of aggressive behaviour by electrical stimulation in the hypothalamus of male rats Behaviour 70 1979 292 322
237. M.R. Kruk, A.M. Van der Poel, W. Meelis, J. Hermans, P.G. Mostert, J. Mos, and A.H. Lohman Discriminant analysis of the localization of aggression-inducing electrode placements in the hypothalamus of male rats Brain Res. 260 1983 61 79
238. M.R. Kruk, K.G. Westphal, A.M. Van Erp, J. van Asperen, B.J. Cave, E. Slater, J. de Koning, and J. Haller The hypothalamus: cross-roads of endocrine and behavioural regulation in grooming and aggression Neurosci. Biobehav. Rev. 23 1998 163 177
239. J.H. Lammers, M.R. Kruk, W. Meelis, and A.M. van der Poel Hypothalamic substrates for brain stimulation-induced attack, teeth-chattering and social grooming in the rat Brain Res. 449 1988 311 327
240. G. Lee, and S.C. Gammie GABA(A) receptor signaling in the lateral septum regulates maternal aggression in mice Behav. Neurosci. 123 2009 1169 1177
241. H.J. Lee, A.H. Macbeth, J.H. Pagani, and W.S. Young 3rd Oxytocin: the great facilitator of life Prog. Neurobiol. 88 2009 127 151
242. H.J. Lee, J. Pagani, and W.S. Young 3rd Using transgenic mouse models to study oxytocins role in the facilitation of species propagation Brain Res. 1364 2010 216 224
243. R.E. Leipheimer, and R.V. Gallo Medial preoptic area involvement in norepinephrine-induced suppression of pulsatile luteinizing hormone release in ovariectomized rats Neuroendocrinology 40 1985 345 351
244. G. Leng, and M. Ludwig Neurotransmitters and peptides: whispered secrets and public announcements J. Physiol. 586 2008 5625 5632
245. G. Leng, T. Onaka, C. Caquineau, N. Sabatier, V.A. Tobin, and Y. Takayanagi Oxytocin and appetite Progress in Brain Res. 170 2008 137 151
246. K.M. Lenz, and D.R. Sengelaub Maternal care effects on the development of a sexually dimorphic motor system: the role of spinal oxytocin Horm. Behav. 58 2010 575 581
247. C. Lewis, B.S. McEwen, and M. Frankfurt Estrogen-induction of dendritic spines in ventromedial hypothalamus and hippocampus: effects of neonatal aromatase blockade and adult GDX Brain Res. Dev. Brain Res. 87 1995 91 95
248. K.C. Light, K.M. Grewen, and J.A. Amico More frequent partner hugs and higher oxytocin levels are linked to lower blood pressure and heart rate in premenopausal women Biol. Psychol. 69 2005 5 21
249. D. Lin, M.P. Boyle, P. Dollar, H. Lee, E.S. Lein, P. Perona, and D.J. Anderson Functional identification of an aggression locus in the mouse hypothalamus Nature 470 2011 221 226
250. D.W. Lincoln, and A.C. Paisley Neuroendocrine control of milk ejection J. Reprod. Fertil. 65 1982 571 586
251. D.W. Lincoln, and J.B. Wakerley Factors governing the periodic activation of supraoptic and paraventricular neurosecretory cells during suckling in the rat J. Physiol. 250 1975 443 461
252. D.W. Lincoln, and J.B. Wakerley Neurosecretory activation in the rat: correlation of the suckling stimulus with the pulsatile release of oxytocin J. Physiol. 245 1975 42P 43P
253. A. Linden Role of cholecystokinin in feeding and lactation Acta Physiol. Scand. Suppl. 585 i-vii 1989 1 49
254. J. Liu, R.W. Rebar, and S.S. Yen Neuroendocrine control of the postpartum period Clin. Perinatol. 10 1983 723 736
255. Y.C. Liu, J.D. Salamone, and B.D. Sachs Impaired sexual response after lesions of the paraventricular nucleus of the hypothalamus in male rats Behav. Neurosci. 111 1997 1361 1367
256. J.S. Lonstein, D.A. Simmons, and J.M. Stern Functions of the caudal periaqueductal gray in lactating rats: kyphosis, lordosis, maternal aggression, and fearfulness Behav. Neurosci. 112 1998 1502 1518
257. C. Looney, K.B. Thor, D. Ricca, and L. Marson Differential effects of simultaneous or sequential administration of paroxetine and WAY-100,635 on ejaculatory behavior Pharmacol.; Biochem.; Behav. 82 2005 427 433
258. M. Ludwig, and G. Leng Dendritic peptide release and peptide-dependent behaviours Nat. Rev. Neurosci. 7 2006 126 136
259. P.G. Luiten, J.M. Koolhaas, S. de Boer, and S.J. Koopmans The cortico-medial amygdala in the central nervous system organization of agonistic behavior Brain Res. 332 1985 283 297
260. M. Lukas, I. Toth, S.O. Reber, D.A. Slattery, A.H. Veenema, and I.D. Neumann The neuropeptide oxytocin facilitates pro-social behavior and prevents social avoidance in rats and mice Neuropsychopharmacol.: Off. Publ. Am. Coll. Neuropsychopharmacol. 36 2011 2159 2168
261. P.G. Lunn Breast-feeding patterns, maternal milk output and lactational infecundity J. Biosoc. Sci. 24 1992 317 324
262. K. Macdonald, and T.M. Macdonald The peptide that binds: a systematic review of oxytocin and its prosocial effects in humans Harvard Rev. Psychiatry 18 2010 1 21
263. M.D. Madeira, L. Ferreira-Silva, and M.M. Paula-Barbosa Influence of sex and estrus cycle on the sexual dimorphisms of the hypothalamic ventromedial nucleus: stereological evaluation and Golgi study J. Comp. Neurol. 432 2001 329 345
264. N. Magon, and S. Kalra The orgasmic history of oxytocin: love, lust, and labor Indian J. Endocrinol. Metab. 15 Suppl 3 2011 S156 S161
265. S. Maguire, A. O'Dell, L. Touyz, and J. Russell Oxytocin and anorexia nervosa: a review of the emerging literature Eur. Eat. Disord. Rev.: J. Eat. Disord. Assoc. 21 2013 475 478
266. K. Mahalati, K. Okanoya, D.M. Witt, and C.S. Carter Oxytocin inhibits male sexual behavior in prairie voles Pharmacol.; Biochem. Behav. 39 1991 219 222
267. G.E. Mann, and G.E. Lamming Relationship between maternal endocrine environment, early embryo development and inhibition of the luteolytic mechanism in cows Reproduction 121 2001 175 180
268. M. Manning, A. Misicka, A. Olma, K. Bankowski, S. Stoev, B. Chini, T. Durroux, B. Mouillac, M. Corbani, and G. Guillon Oxytocin and vasopressin agonists and antagonists as research tools and potential therapeutics J. Neuroendocrinol. 24 2012 609 628
269. L. Marson Central nervous system neurons identified after injection of pseudorabies virus into the rat clitoris Neurosci. Lett. 190 1995 41 44
270. L. Marson, and K.E. McKenna CNS cell groups involved in the control of the ischiocavernosus and bulbospongiosus muscles: a transneuronal tracing study using pseudorabies virus J. Comp. Neurol. 374 1996 161 179
271. L. Marson, K.B. Platt, and K.E. McKenna Central nervous system innervation of the penis as revealed by the transneuronal transport of pseudorabies virus Neuroscience 55 1993 263 280
272. D. Mathews, and D.A. Edwards Involvement of the ventromedial and anterior hypothalamic nuclei in the hormonal induction of receptivity in the female rat Physiol. Behav. 19 1977 319 326
273. D. Mathews, and D.A. Edwards The ventromedial nucleus of the hypothalamus and the hormonal arousal of sexual behaviors in the female rat Horm. Behav. 8 1977 40 51
274. A. Matsumoto, and Y. Arai Sex difference in volume of the ventromedial nucleus of the hypothalamus in the rat Endocrinol. Jpn. 30 1983 277 280
275. A.D. Mayer, and J.S. Rosenblatt Hormonal factors influence the onset of maternal aggression in laboratory rats Horm. Behav. 21 1987 253 267
276. M.M. McCarthy Estrogen modulation of oxytocin and its relation to behavior Adv. Exp. Med. Biol. 395 1995 235 245
277. M.M. McCarthy, J.E. Bare, and F.S. vom Saal Infanticide and parental behavior in wild female house mice: effects of ovariectomy, adrenalectomy and administration of oxytocin and prostaglandin F2 alpha Physiol. Behav. 36 1986 17 23
278. M.M. McCarthy, G.H. Curran, and H.H. Feder Excitatory amino acid modulation of lordosis in the rat Neurosci. Lett. 126 1991 94 97
279. M.M. McCarthy, L.C. Kaufman, P.J. Brooks, D.W. Pfaff, and S. Schwartz-Giblin Estrogen modulation of mRNA levels for the two forms of glutamic acid decarboxylase (GAD) in female rat brain J. Comp. Neurol. 360 1995 685 697
280. M.M. McCarthy, S.P. Kleopoulos, C.V. Mobbs, and D.W. Pfaff Infusion of antisense oligodeoxynucleotides to the oxytocin receptor in the ventromedial hypothalamus reduces estrogen-induced sexual receptivity and oxytocin receptor binding in the female rat Neuroendocrinology 59 1994 432 440
281. M.M. McCarthy, and A.T. Konkle When is a sex difference not a sex difference? Front. Neuroendocrinol. 26 2005 85 102
282. M.M. McCarthy, L.M. Kow, and D.W. Pfaff Speculations concerning the physiological significance of central oxytocin in maternal behavior Ann. N. Y. Acad. Sci. 652 1992 70 82
283. M.M. McCarthy, K.F. Malik, and H.H. Feder Increased GABAergic transmission in medial hypothalamus facilitates lordosis but has the opposite effect in preoptic area Brain Res. 507 1990 40 44
284. M.M. McCarthy, D.B. Masters, J.M. Fiber, A.M. Lopez-Colome, C. Beyer, B.R. Komisaruk, and H.H. Feder GABAergic control of receptivity in the female rat Neuroendocrinology 53 1991 473 479
285. B.S. McEwen Genomic regulation of sexual behavior J. Steroid Biochem. 30 1988 179 183
286. A.S. McNeilly Neuroendocrine changes and fertility in breast-feeding women Prog. Brain Res. 133 2001 207 214
287. P. Melin, and J.E. Kihlstroem Influence of oxytocin on sexual behavior in male rabbits Endocrinology 73 1963 433 435
288. M.R. Melis, and A. Argiolas Central control of penile erection: a re-visitation of the role of oxytocin and its interaction with dopamine and glutamic acid in male rats Neurosci. Biobehav. Rev. 35 2011 939 955
289. M.R. Melis, A. Argiolas, and G.L. Gessa Oxytocin-induced penile erection and yawning: site of action in the brain Brain Res. 398 1986 259 265
290. M.R. Melis, T. Melis, C. Cocco, S. Succu, F. Sanna, G. Pillolla, A. Boi, G.L. Ferri, and A. Argiolas Oxytocin injected into the ventral tegmental area induces penile erection and increases extracellular dopamine in the nucleus accumbens and paraventricular nucleus of the hypothalamus of male rats Eur. J. Neurosci. 26 2007 1026 1035
291. M.R. Melis, M.S. Spano, S. Succu, and A. Argiolas The oxytocin antagonist d(CH2)5Tyr(Me)2-Orn8-vasotocin reduces non-contact penile erections in male rats Neurosci. Lett. 265 1999 171 174
292. M.R. Melis, S. Succu, F. Sanna, A. Boi, and A. Argiolas Oxytocin injected into the ventral subiculum or the posteromedial cortical nucleus of the amygdala induces penile erection and increases extracellular dopamine levels in the nucleus accumbens of male rats Eur. J. Neurosci. 30 2009 1349 1357
293. S.D. Mendelson, and B.B. Gorzalka A facilitatory role for serotonin in the sexual behavior of the female rat Pharmacol.; Biochem. Behav. 22 1985 1025 1033
294. W.B. Mens, A. Witter, and T.B. van Wimersma Greidanus Penetration of neurohypophyseal hormones from plasma into cerebrospinal fluid (CSF): half-times of disappearance of these neuropeptides from CSF Brain Res. 262 1983 143 149
295. J.R. Menzies, K.P. Skibicka, S.L. Dickson, and G. Leng Neural substrates underlying interactions between appetite stress and reward Obes. Facts 5 2012 208 220
296. A. Meyer-Lindenberg Impact of prosocial neuropeptides on human brain function Prog. Brain Res. 170 2008 463 470
297. O.E. Millhouse Certain ventromedial hypothalamic afferents Brain Res. 55 1973 89 105
298. O.E. Millhouse The organization of the ventromedial hypothalamic nucleus Brain Res. 55 1973 71 87
299. O.E. Millhouse Cytological observations on the ventromedial hypothalamic nucleus Cell Tissue Res. 191 1978 473 491
300. K. Miyamichi, F. Amat, F. Moussavi, C. Wang, I. Wickersham, N.R. Wall, H. Taniguchi, B. Tasic, Z.J. Huang, Z. He, E.M. Callaway, M.A. Horowitz, and L. Luo Cortical representations of olfactory input by trans-synaptic tracing Nature 472 2011 191 196
301. H. Mizusawa, P. Hedlund, and K.E. Andersson alpha-Melanocyte stimulating hormone and oxytocin induced penile erections, and intracavernous pressure increases in the rat J. Urol. 167 2002 757 760
302. K.M. Moody, and N.T. Adler The role of the uterus and cervix in systemic oxytocin-PGE2 facilitated lordosis behavior Horm. Behav. 29 1995 571 580
303. K.M. Moody, J.L. Steinman, B.R. Komisaruk, and N.T. Adler Pelvic neurectomy blocks oxytocin-facilitated sexual receptivity in rats Physiol. Behav. 56 1994 1057 1060
304. F. Moos, D.A. Poulain, F. Rodriguez, Y. Guerne, J.D. Vincent, and P. Richard Release of oxytocin within the supraoptic nucleus during the milk ejection reflex in rats Exp. Brain Res. 76 1989 593 602
305. F. Moos, and P. Richard [Level of oxytocin release induced by vaginal dilatation (Ferguson reflex) and vagal stimulation (vago-pituitary reflex) in lactating rats (author's transl)] J. Physiol. 70 1975 307 314
306. F. Moos, and P. Richard Paraventricular and supraoptic bursting oxytocin cells in rat are locally regulated by oxytocin and functionally related J. Physiol. 408 1989 1 18
307. J. Mos, B. Olivier, J.H. Lammers, A.M. van der Poel, M.R. Kruk, and T. Zethof Postpartum aggression in rats does not influence threshold currents for EBS-induced aggression Brain Res. 404 1987 263 266
308. L.R. Moscovice, and T.E. Ziegler Peripheral oxytocin in female baboons relates to estrous state and maintenance of sexual consortships Horm. Behav. 62 2012 592 597
309. R.L. Moss, and M.M. Foreman Potentiation of lordosis behavior by intrahypothalamic infusion of synthetic luteinizing hormone-releasing hormone Neuroendocrinology 20 1976 176 181
310. S.C. Motta, C.C. Guimaraes, I.C. Furigo, M.H. Sukikara, M.V. Baldo, J.S. Lonstein, and N.S. Canteras Ventral premammillary nucleus as a critical sensory relay to the maternal aggression network Proc. Natl. Acad. Sci. USA 110 2013 14438 14443
311. K. Mullis, K. Kay, and D.L. Williams Oxytocin action in the ventral tegmental area affects sucrose intake Brain Res. 1513 2013 85 91
312. A.Z. Murphy, and G.E. Hoffman Distribution of gonadal steroid receptor-containing neurons in the preoptic-periaqueductal gray-brainstem pathway: a potential circuit for the initiation of male sexual behavior J. Comp. Neurol. 438 2001 191 212
313. M.R. Murphy, J.R. Seckl, S. Burton, S.A. Checkley, and S.L. Lightman Changes in oxytocin and vasopressin secretion during sexual activity in men J. Clin. Endocrinol. Metab. 65 1987 738 741
314. F. Naber, M.H. van Ijzendoorn, P. Deschamps, H. van Engeland, and M.J. Bakermans-Kranenburg Intranasal oxytocin increases fathers' observed responsiveness during play with their children: a double-blind within-subject experiment Psychoneuroendocrinology 35 2010 1583 1586
315. S. Nagayama, A. Enerva, M.L. Fletcher, A.V. Masurkar, K.M. Igarashi, K. Mori, and W.R. Chen Differential axonal projection of mitral and tufted cells in the mouse main olfactory system Front. Neural Circuits 2010 4
316. I.D. Neumann Alterations in behavioral and neuroendocrine stress coping strategies in pregnant, parturient and lactating rats Prog. Brain Res. 133 2001 143 152
317. I.D. Neumann Involvement of the brain oxytocin system in stress coping: interactions with the hypothalamo-pituitary-adrenal axis Prog Brain Res 139 2002 147 162
318. I.D. Neumann Brain mechanisms underlying emotional alterations in the peripartum period in rats Depress Anxiety 17 2003 111 121
319. I.D. Neumann Brain oxytocin: a key regulator of emotional and social behaviours in both females and males J. Neuroendocrinol. 20 2008 858 865
320. I.D. Neumann, O.J. Bosch, N. Toschi, L. Torner, and A.J. Douglas No stress response of the hypothalamo-pituitary-adrenal axis in parturient rats: lack of involvement of brain oxytocin Endocrinology 144 2003 2473 2479
321. I.D. Neumann, and R. Landgraf Balance of brain oxytocin and vasopressin: implications for anxiety, depression, and social behaviors Trends Neurosci. 35 2012 649 659
322. I.D. Neumann, N. Toschi, F. Ohl, L. Torner, and S.A. Kromer Maternal defence as an emotional stressor in female rats: correlation of neuroendocrine and behavioural parameters and involvement of brain oxytocin Eur. J. Neurosci. 13 2001 1016 1024
323. I.D. Neumann, R. Maloumby, D.I. Beiderbeck, M. Lukas, and R. Landgraf Increased brain and plasma oxytocin after nasal and peripheral administration in rats and mice Psychoneuroendocrinology 38 2013 1985 1993
324. R. Nieuwenhuys, L.M. Geeraedts, and J.G. Veening The medial forebrain bundle of the rat. I Gen. Introd. J. Comp. Neurol. 206 1982 49 81
325. K. Nishimori, L.J. Young, Q. Guo, Z. Wang, T.R. Insel, and M.M. Matzuk Oxytocin is required for nursing but is not essential for parturition or reproductive behavior Proc. Natl. Acad. Sci. USA 93 1996 11699 11704
326. S. Nishitani, T. Moriya, Y. Kondo, Y. Sakuma, and K. Shinohara Induction of Fos immunoreactivity in oxytocin neurons in the paraventricular nucleus after female odor exposure in male rats: effects of sexual experience Cell. Mol. Neurobiol. 24 2004 283 291
327. J.J. Normandin, and A.Z. Murphy Somatic genital reflexes in rats with a nod to humans: anatomy, physiology, and the role of the social neuropeptides Horm. Behav. 59 2011 656 665
328. L.E. Northrop, and M.S. Erskine Selective oxytocin receptor activation in the ventrolateral portion of the ventromedial hypothalamus is required for mating-induced pseudopregnancy in the female rat Endocrinology 149 2008 836 842
329. M. Numan Motivational systems and the neural circuitry of maternal behavior in the rat Dev. Psychobiol. 49 2007 12 21
330. M. Numan, M.J. Numan, J.M. Schwarz, C.M. Neuner, T.F. Flood, and C.D. Smith Medial preoptic area interactions with the nucleus accumbens-ventral pallidum circuit and maternal behavior in rats Behav. Brain Res. 158 2005 53 68
331. M. Numan, and T.P. Sheehan Neuroanatomical circuitry for mammalian maternal behavior Ann. N. Y. Acad. Sci. 807 1997 101 125
332. K.D. Nyuyki, M. Waldherr, S. Baeuml, and I.D. Neumann Yes, I am ready now: differential effects of paced versus unpaced mating on anxiety and central oxytocin release in female rats PloS One 6 2011 e23599
333. L.A. O'Connell, B.J. Matthews, and H.A. Hofmann Isotocin regulates paternal care in a monogamous cichlid fish Horm. Behav. 61 2012 725 733
334. A.M. Oboh, R.G. Paredes, and M.J. Baum A sex comparison of increments in FOS immunoreactivity in forebrain neurons of gonadectomized, testosterone-treated rats after mounting an estrous female Neurobiol. Learn. Mem. 63 1995 66 73
335. S. Ogawa, L.-M. Kow, M.M. McCarthy, D. Pfaff, and W. Schwartz-Giblin, S. Midbrain PAG control of female reproductive behavior: in vitro electrophysiological characterization of lordosis-relevant substances A. Depaulis, R. Bandler, The Midbrain Periaqyeductal Gray Matter 1991 Plenum Press New York 211 235
336. S. Ogawa, L.M. Kow, and D.W. Pfaff Effects of lordosis-relevant neuropeptides on midbrain periaqueductal gray neuronal activity in vitro Peptides 13 1992 965 975
337. S. Ogawa, D.B. Lubahn, K.S. Korach, and D.W. Pfaff Behavioral effects of estrogen receptor gene disruption in male mice Proc. Natl. Acad. Sci. USA 94 1997 1476 1481
338. D.E. Olazabal, and A. Ferreira Maternal behavior in rats with kainic acid-induced lesions of the hypothalamic paraventricular nucleus Physiol. Behav. 61 1997 779 784
339. D.E. Olazabal, M. Pereira, D. Agrati, A. Ferreira, A.S. Fleming, G. Gonzalez-Mariscal, F. Levy, A.B. Lucion, J.I. Morrell, M. Numan, and N. Uriarte New theoretical and experimental approaches on maternal motivation in mammals Neurosci. Biobehav. Rev. 37 2013 1860 1874
340. B. Olivier, and P.R. Wiepkema Behaviour changes in mice following electrolytic lesions in the median hypothalamus Brain Res. 65 1974 521 524
341. D.H. Olster, and J.D. Blaustein Progesterone facilitates lordosis, but not LH release, in estradiol pulse-primed male rats Physiol. Behav. 50 1991 237 242
342. P.K. Olszewski, A. Klockars, H.B. Schioth, and A.S. Levine Oxytocin as feeding inhibitor: maintaining homeostasis in consummatory behavior Pharmacol.; Biochem. Behav. 97 2010 47 54
343. T. Ono, H. Nishino, K. Sasaka, K. Muramoto, I. Yano, and A. Simpson Paraventricular nucleus connections to spinal cord and pituitary Neurosci. Lett. 10 1978 141 146
344. R. Orr, and L. Marson Identification of CNS neurons innervating the rat prostate: a transneuronal tracing study using pseudorabies virus J. Auton. Nerv. Syst. 72 1998 4 15
345. C.W. Palmer, S.D. Amundson, L.F. Brito, C.L. Waldner, and A.D. Barth Use of oxytocin and cloprostenol to facilitate semen collection by electroejaculation or transrectal massage in bulls Anim. Reprod. Sci. 80 2004 213 223
346. J. Panksepp The basic emotional circuits of mammalian brains: do animals have affective lives? Neurosci. Biobehav. Rev. 35 2011 1791 1804
347. M. Parada, L. Chamas, S. Censi, G. Coria-Avila, and J.G. Pfaus Clitoral stimulation induces conditioned place preference and Fos activation in the rat Horm. Behav. 57 2010 112 118
348. J.A. Parker, and S.R. Bloom Hypothalamic neuropeptides and the regulation of appetite Neuropharmacology 63 2012 18 30
349. K.J. Parker, and T.M. Lee Social and environmental factors influence the suppression of pup-directed aggression and development of paternal behavior in captive meadow voles (Microtus pennsylvanicus) J. Comp. Psychol. 115 2001 331 336
350. T. Pattij, T.R. de Jong, A. Uitterdijk, M.D. Waldinger, J.G. Veening, A.R. Cools, P.H. van der Graaf, and B Olivier Individual differences in male rat ejaculatory behaviour: searching for models to study ejaculation disorders Eur. J. Neurosci. 22 2005 724 734
351. A. Pedersen, and M.L. Tomaszycki Oxytocin antagonist treatments alter the formation of pair relationships in zebra finches of both sexes Horm. Behav. 62 2012 113 119
352. C.A. Pedersen, and M.L. Boccia Oxytocin maintains as well as initiates female sexual behavior: effects of a highly selective oxytocin antagonist Horm. Behav. 41 2002 170 177
353. C.A. Pedersen, and M.L. Boccia Vasopressin interactions with oxytocin in the control of female sexual behavior Neuroscience 139 2006 843 851
354. C.A. Pedersen, J.D. Caldwell, C. Walker, G. Ayers, and G.A. Mason Oxytocin activates the postpartum onset of rat maternal behavior in the ventral tegmental and medial preoptic areas Behav. Neurosci. 108 1994 1163 1171
355. M. Perello, and J. Raingo Leptin activates oxytocin neurons of the hypothalamic paraventricular nucleus in both control and diet-induced obese rodents PloS One 8 2013 e59625
356. A.N. Perry, A. Paramadilok, and B.S. Cushing Neonatal oxytocin alters subsequent estrogen receptor alpha protein expression and estrogen sensitivity in the female rat Behav. Brain Res. 205 2009 154 161
357. L.C. Peters, M.B. Kristal, and B.R. Komisaruk Sensory innervation of the external and internal genitalia of the female rat Brain Res. 408 1987 199 204
358. D.;W Pfaff Estrogens and Brain Function 1980 Springer Verlag New York
359. D.; W Pfaff Man and Woman: An Insidsse Story 2011 Oxford University Press USA
360. D.; W. Pfaff, and Y. Sakuma Facilitation of the lordosis reflex of female rats from the ventromedial nucleus of the hypothalamus J. Physiol. 288 1979 189 202
361. D.W. Pfaff, B.L. Kieffer, and L.W. Swanson Mechanisms for the regulation of state changes in the central nervous system: an introduction Ann. N. Y. Acad. Sci. 1129 2008 1 7
362. D.W. Pfaff, and C. Lewis Film analyses of lordosis in female rats Horm. Behav. 5 1974 317 335
363. D.W. Pfaff, and Y. Sakuma Deficit in the lordosis reflex of female rats caused by lesions in the ventromedial nucleus of the hypothalamus J. Physiol. 288 1979 203 210
364. D.W. Pfaff, and Y. Sakuma Deficit in the lordosis reflex of female rats caused by lesions in the ventromedial nucleus of the hypothalamus J. Physiol. 288 1979 203 210
365. D.W. Pfaff, and Y. Sakuma Facilitation of the lordosis reflex of female rats from the ventromedial nucleus of the hypothalamus J. Physiol. 288 1979 189 202
366. J.G. Pfaus Pathways of sexual desire J. Sex. Med. 6 2009 1506 1533
367. J.G. Pfaus, G. Damsma, D. Wenkstern, and H.C. Fibiger Sexual activity increases dopamine transmission in the nucleus accumbens and striatum of female rats Brain Res. 693 1995 21 30
368. J.G. Pfaus, and M.M. Heeb Implications of immediate-early gene induction in the brain following sexual stimulation of female and male rodents Brain Res. Bull. 44 1997 397 407
369. J.G. Pfaus, A. Jakob, S.P. Kleopoulos, R.B. Gibbs, and D.W. Pfaff Sexual stimulation induces Fos immunoreactivity within GnRH neurons of the female rat preoptic area: interaction with steroid hormones Neuroendocrinology 60 1994 283 290
370. J.G. Pfaus, T.E. Kippin, G.A. Coria-Avila, H. Gelez, V.M. Afonso, N. Ismail, and M. Parada Who, what, where, when (and maybe even why)? How the experience of sexual reward connects sexual desire, preference, and performance Arch. Sex. Behav. 41 2012 31 62
371. J.G. Pfaus, S.P. Kleopoulos, C.V. Mobbs, R.B. Gibbs, and D.W. Pfaff Sexual stimulation activates c-fos within estrogen-concentrating regions of the female rat forebrain Brain Res. 624 1993 253 267
372. J.G. Pfaus, C. Manitt, and C.B. Coopersmith Effects of pelvic, pudendal, or hypogastric nerve cuts on Fos induction in the rat brain following vaginocervical stimulation Physiol. Behav. 89 2006 627 636
373. J.G. Pfaus, C. Marcangione, W.J. Smith, C. Manitt, and H. Abillamaa Differential induction of Fos in the female rat brain following different amounts of vaginocervical stimulation: modulation by steroid hormones Brain Res. 741 1996 314 330
374. J.G. Pfaus, W.J. Smith, N. Byrne, and G. Stephens Appetitive and consummatory sexual behaviors of female rats in bilevel chambers. II. Patterns of estrus termination following vaginocervical stimulation Horm. Behav. 37 2000 96 107
375. J.G. Pfaus, W.J. Smith, and C.B. Coopersmith Appetitive and consummatory sexual behaviors of female rats in bilevel chambers. I. A correlational and factor analysis and the effects of ovarian hormones Horm. Behav. 35 1999 224 240
376. J.K. Pfeifle, M. Shivers, and D.A. Edwards Parasagittal hypothalamic knife cuts and sexual receptivity in the female rat Physiol. Behav. 24 1980 145 150
377. E.T. Pleim, and R.J. Barfield Progesterone versus estrogen facilitation of female sexual behavior by intracranial administration to female rats Horm. Behav. 22 1988 150 159
378. E.T. Pleim, J. Baumann, and R.J. Barfield A contributory role for midbrain progesterone in the facilitation of female sexual behavior in rats Horm. Behav. 25 1991 19 28
379. E.T. Pleim, T.J. Brown, N.J. MacLusky, A.M. Etgen, and R.J. Barfield Dilute estradiol implants and progestin receptor induction in the ventromedial nucleus of the hypothalamus: correlation with receptive behavior in female rats Endocrinology 124 1989 1807 1812
380. E.K. Polston, and M.S. Erskine Patterns of induction of the immediate-early genes c-fos and egr-1 in the female rat brain following differential amounts of mating stimulation Neuroendocrinology 62 1995 370 384
381. A.K. Ragnauth, N. Devidze, V. Moy, K. Finley, A. Goodwillie, L.M. Kow, L.J. Muglia, and D.W. Pfaff Female oxytocin gene-knockout mice, in a semi-natural environment, display exaggerated aggressive behavior Genes, Brain, Behav. 4 2005 229 239
382. G. Rajendren, C.A. Dudley, and R.L. Moss Role of the ventromedial nucleus of hypothalamus in the male-induced enhancement of lordosis in female rats Physiol. Behav. 50 1991 705 710
383. E. Ramos, A. Castilla, N. Navarro, N. Monasterio, F. Mena, and T. Morales Suckling-induced oxytocin increase in the spinal cord of the rat Brain Res. 1236 2008 85 92
384. C.H. Rhodes, J.I. Morrell, and D.W. Pfaff Immunohistochemical analysis of magnocellular elements in rat hypothalamus: distribution and numbers of cells containing neurophysin, oxytocin, and vasopressin J. Comp. Neurol. 198 1981 45 64
385. I.C. Robinson, and P.M. Jones Oxytocin and neurophysin in plasma and CSF during suckling in the guinea-pig Neuroendocrinology 34 1982 59 63
386. T.A. Roeling, J.G. Veening, M.R. Kruk, J.P. Peters, M.E. Vermelis, and R. Nieuwenhuys Efferent connections of the hypothalamic "aggression area" in the rat Neuroscience 59 1994 1001 1024
387. A. Romano, C.S. Potes, B. Tempesta, T. Cassano, V. Cuomo, T. Lutz, and S. Gaetani Hindbrain noradrenergic input to the hypothalamic PVN mediates the activation of oxytocinergic neurons induced by the satiety factor oleoylethanolamide Am. J. Physiol. Endocrinol. Metab. 305 2013 E1266 E1273
388. G.J. Romano, R.E. Harlan, B.D. Shivers, R.D. Howells, and D.W. Pfaff Estrogen increases proenkephalin messenger ribonucleic acid levels in the ventromedial hypothalamus of the rat Mol. Endocrinol. 2 1988 1320 1328
389. G.J. Romano, C.V. Mobbs, A. Lauber, R.D. Howells, and D.W. Pfaff Differential regulation of proenkephalin gene expression by estrogen in the ventromedial hypothalamus of male and female rats: implications for the molecular basis of a sexually differentiated behavior Brain Res. 536 1990 63 68
390. J.S. Rosenblatt, A.D. Mayer, and A.L. Giordano Hormonal basis during pregnancy for the onset of maternal behavior in the rat Psychoneuroendocrinology 13 1988 29 46
391. H.E. Ross, C.D. Cole, Y. Smith, I.D. Neumann, R. Landgraf, A.Z. Murphy, and L.J. Young Characterization of the oxytocin system regulating affiliative behavior in female prairie voles Neuroscience 162 2009 892 903
392. H.E. Ross, and L.J. Young Oxytocin and the neural mechanisms regulating social cognition and affiliative behavior Front. Neuroendocrinol. 30 2009 534 547
393. E. Rossoni, J. Feng, B. Tirozzi, D. Brown, G. Leng, and F. Moos Emergent synchronous bursting of oxytocin neuronal network PLoS Comput. Biol. 4 2008 e1000123
394. D.W. Rowe, and M.S. Erskine c-Fos proto-oncogene activity induced by mating in the preoptic area, hypothalamus and amygdala in the female rat: role of afferent input via the pelvic nerve Brain Res. 621 1993 25 34
395. B.S. Rubin, and R.J. Barfield Induction of estrous behavior in ovariectomized rats by sequential replacement of estrogen and progesterone to the ventromedial hypothalamus Neuroendocrinology 37 1983 218 224
396. H.A. Rupp, T.W. James, E.D. Ketterson, D.R. Sengelaub, B. Ditzen, and J.R. Heiman Lower sexual interest in postpartum women: relationship to amygdala activation and intranasal oxytocin Horm. Behav. 63 2013 114 121
397. J.A. Russell, A.J. Douglas, and C.D. Ingram Brain preparations for maternity - adaptive changes in behavioral and neuroendocrine systems during pregnancy and lactation. An overview Prog. Brain Res. 133 2001 1 38
398. S.I. Sa, and M.D. Madeira Estrogen modulates the sexually dimorphic synaptic connectivity of the ventromedial nucleus J. Comp. Neurol. 484 2005 68 79
399. N. Sabatier, G. Leng, and J. Menzies Oxytocin, feeding, and satiety Front. Endocrinol. 4 2013 35
400. A. Saito, and K. Nakamura Oxytocin changes primate paternal tolerance to offspring in food transfer J. Comp. Physiol. A, Neuroethol.; Sens.; Neural, Behav. Physiol. 197 2011 329 337
401. Y. Sakuma, and D. Pfaff Electrophysiologic determination of projections from ventromedial hypothalamus to midbrain central gray: differences between female and male rats Brain Res. 225 1981 184 188
402. Y. Sakuma, and D.W. Pfaff Facilitation of female reproductive behavior from mesensephalic central gray in the rat Am. J. Physiol. 237 1979 R278 R284
403. Y. Sakuma, and D.W. Pfaff LH-RH in the mesencephalic central grey can potentiate lordosis reflex of female rats Nature 283 1980 566 567
404. Y. Sakuma, and D.W. Pfaff Properties of ventromedial hypothalamic neurons with axons to midbrain central gray Exp. Brain Res. Exp. Hirnforsch. Exp. cerebr. 46 1982 292 300
405. A. Salonia, R.E. Nappi, M. Pontillo, R. Daverio, A. Smeraldi, A. Briganti, F. Fabbri, G. Zanni, P. Rigatti, and F. Montorsi Menstrual cycle-related changes in plasma oxytocin are relevant to normal sexual function in healthy women Horm. Behav. 47 2005 164 169
406. W.K. Samson, S.M. McCann, L. Chud, C.A. Dudley, and R.L. Moss Intra- and extrahypothalamic luteinizing hormone-releasing hormone (LHRH) distribution in the rat with special reference to mesencephalic sites which contain both LHRH and single neurons responsive to LHRH Neuroendocrinology 31 1980 66 72
407. G.R. Sansone, and B.R. Komisaruk Evidence that oxytocin is an endogenous stimulator of autonomic sympathetic preganglionics: the pupillary dilatation response to vaginocervical stimulation in the rat Brain Res. 898 2001 265 271
408. C.B. Saper Animal behaviour: the nexus of sex and violence Nature 470 2011 179 181
409. P.E. Sawchenko, and L.W. Swanson Immunohistochemical identification of neurons in the paraventricular nucleus of the hypothalamus that project to the medulla or to the spinal cord in the rat J. Comp. Neurol. 205 1982 260 272
410. P.E. Sawchenko, and L.W. Swanson Immunohistochemical identification of neurons in the paraventricular nucleus of the hypothalamus that project to the medulla or to the spinal cord in the rat J. Comp. Neurol. 205 1982 260 272
411. I. Schneiderman, O. Zagoory-Sharon, J.F. Leckman, and R. Feldman Oxytocin during the initial stages of romantic attachment: relations to couples interactive reciprocity Psychoneuroendocrinology 37 2012 1277 1285
412. H.G. Schulze, and B.B. Gorzalka Oxytocin effects on lordosis frequency and lordosis duration following infusion into the medial pre-optic area and ventromedial hypothalamus of female rats Neuropeptides 18 1991 99 106
413. H.G. Schulze, and B.B. Gorzalka Low concentrations of oxytocin suppress lordosis when infused into the lateral ventricle of female rats Endocr. Regul. 26 1992 23 27
414. M. Schumacher, H. Coirini, M. Frankfurt, and B.S. McEwen Localized actions of progesterone in hypothalamus involve oxytocin Proc. Natl. Acad. Sci. USA 86 1989 6798 6801
415. M. Schumacher, H. Coirini, D.W. Pfaff, and B.S. McEwen Behavioral effects of progesterone associated with rapid modulation of oxytocin receptors Science 250 1990 691 694
416. M. Schumacher, H. Coirini, D.W. Pfaff, and B.S. McEwen Light-dark differences in behavioral sensitivity to oxytocin Behav. Neurosci. 105 1991 487 492
417. M. Schwanzel-Fukuda, J.I. Morrell, and D.W. Pfaff Localization of forebrain neurons which project directly to the medulla and spinal cord of the rat by retrograde tracing with wheat germ agglutinin J. Comp. Neurol. 226 1984 1 20
418. S. Segovia, A. Garcia-Falgueras, C. Perez-Laso, H. Pinos, B. Carrillo, P. Collado, F. Claro, and A. Guillamon The effects of partial and complete masculinization on the sexual differentiation of nuclei that control lordotic behavior in the male rat Behav. Brain Res. 196 2009 261 267
419. D.N. Shelley, E. Choleris, M. Kavaliers, and D.W. Pfaff Mechanisms underlying sexual and affiliative behaviors of mice: relation to generalized CNS arousal Soc. Cogn. Affect. Neurosci. 1 2006 260 270
420. A. Siegel, T.A. Roeling, T.R. Gregg, and M.R. Kruk Neuropharmacology of brain-stimulation-evoked aggression Neurosci. Biobehav. Rev. 23 1999 359 389
421. B.A. Silva, C. Mattucci, P. Krzywkowski, E. Murana, A. Illarionova, V. Grinevich, N.S. Canteras, D. Ragozzino, and C.T. Gross Independent hypothalamic circuits for social and predator fear Nat. Neurosci. 16 2013 1731 1733
422. D.J. Sirinathsinghji Modulation of lordosis behaviour in the female rat by corticotropin releasing factor, beta-endorphin and gonadotropin releasing hormone in the mesencephalic central gray Brain Res. 336 1985 45 55
423. D.J. Sirinathsinghji Regulation of lordosis behaviour in the female rat by corticotropin-releasing factor, beta-endorphin/corticotropin and luteinizing hormone-releasing hormone neuronal systems in the medial preoptic area Brain Res. 375 1986 49 56
424. E.M. Snoeren, J.G. Veening, B. Olivier, and R.S. Oosting Serotonin 1A receptors and sexual behavior in female rats: a review Pharmacol.; Biochem.; Behav. 2013
425. E.M. Snoeren, J.G. Veening, B. Olivier, and R.S. Oosting Serotonin 1A receptors and sexual behavior in male rats: a review Pharmacol.; Biochem.; Behav. 2013
426. C.T. Snowdon, B.A. Pieper, C.Y. Boe, K.A. Cronin, A.V. Kurian, and T.E. Ziegler Variation in oxytocin is related to variation in affiliative behavior in monogamous, pairbonded tamarins Horm. Behav. 58 2010 614 618
427. L.G. Sobrinho The psychogenic effects of prolactin Acta Endocrinol. 129 Suppl 1 1993 S38 S40
428. Z. Song, F. Tai, C. Yu, R. Wu, X. Zhang, H. Broders, F. He, and R. Guo Sexual or paternal experiences alter alloparental behavior and the central expression of ERalpha and OT in male mandarin voles (Microtus mandarinus) Behav. Brain Res. 214 2010 290 300
429. D.L. Sosulski, M.L. Bloom, T. Cutforth, R. Axel, and S.R. Datta Distinct representations of olfactory information in different cortical centres Nature 472 2011 213 216
430. J.M. Stern, and J.M. Kolunie Maternal aggression of rats is impaired by cutaneous anesthesia of the ventral trunk, but not by nipple removal Physiol. Behav. 54 1993 861 868
431. M.D. Stoneham, B.J. Everitt, S. Hansen, S.L. Lightman, and K. Todd Oxytocin and sexual behaviour in the male rat and rabbit J. Endocrinol. 107 1985 97 106
432. N. Striepens, K.M. Kendrick, W. Maier, and R. Hurlemann Prosocial effects of oxytocin and clinical evidence for its therapeutic potential Front. Neuroendocrinol. 32 2011 426 450
433. A.J. Summerlee Extracellular recordings from oxytocin neurones during the expulsive phase of birth in unanaesthetized rats J. Physiol. 321 1981 1 9
434. A.J. Summerlee, and D.W. Lincoln Electrophysiological recordings from oxytocinergic neurones during suckling in the unanaesthetized lactating rat J. Endocrinol. 90 1981 255 265
435. K. Svennersten-Sjaunja, and K. Olsson Endocrinology of milk production Domest. Anim. Endocrinol. 29 2005 241 258
436. L.W. Swanson The Hypothalamus A. Bjöeklund, T Hökfelt, L.W Swanson, Integrated Systems of the CNS part 1 1987 Elsevier Amsterdam 1 124
437. L.W. Swanson, and H.G. Kuypers The paraventricular nucleus of the hypothalamus: cytoarchitectonic subdivisions and organization of projections to the pituitary, dorsal vagal complex, and spinal cord as demonstrated by retrograde fluorescence double-labeling methods J. Comp. Neurol. 194 1980 555 570
438. L.W. Swanson, and S. McKellar The distribution of oxytocin- and neurophysin-stained fibers in the spinal cord of the rat and monkey J. Comp. Neurol. 188 1979 87 106
439. L.W. Swanson, and S. McKellar The distribution of oxytocin- and neurophysin-stained fibers in the spinal cord of the rat and monkey J. Comp. Neurol. 188 1979 87 106
440. L.K. Takahashi, and R.K. Lore Intermale and maternal aggression in adult rats tested at different ages Physiol. Behav. 29 1982 1013 1018
441. S.K. Tallam, J.S. Walton, and W.H. Johnson Effects of oxytocin on follicular development and duration of the estrous cycle in heifers Theriogenology 53 2000 951 962
442. Y. Tang, O. Rampin, A. Calas, P. Facchinetti, and F. Giuliano Oxytocinergic and serotonergic innervation of identified lumbosacral nuclei controlling penile erection in the male rat Neuroscience 82 1998 241 254
443. Y. Tang, O. Rampin, F. Giuliano, and G. Ugolini Spinal and brain circuits to motoneurons of the bulbospongiosus muscle: retrograde transneuronal tracing with rabies virus J. Comp. Neurol. 414 1999 167 192
444. M.J. Tetel, D.C. Celentano, and J.D. Blaustein Intraneuronal convergence of tactile and hormonal stimuli associated with female reproduction in rats J. Neuroendocrinol. 6 1994 211 216
445. M.J. Tetel, M.J. Getzinger, and J.D. Blaustein Fos expression in the rat brain following vaginal-cervical stimulation by mating and manual probing J. Neuroendocrinol. 5 1993 397 404
446. M.J. Tetel, M.J. Getzinger, and J.D. Blaustein Estradiol and progesterone influence the response of ventromedial hypothalamic neurons to tactile stimuli associated with female reproduction Brain Res. 646 1994 267 272
447. D.T. Theodosis Oxytocin-secreting neurons: a physiological model of morphological neuronal and glial plasticity in the adult hypothalamus Front. Neuroendocrinol. 23 2002 101 135
448. S. Tsukahara, N. Ezawa, and K. Yamanouchi Neonatal estrogen decreases neural density of the septum-midbrain central gray connection underlying the lordosis-inhibiting system in female rats Neuroendocrinology 78 2003 226 233
449. S. Tsukahara, and K. Yamanouchi Neurohistological and behavioral evidence for lordosis-inhibiting tract from lateral septum to periaqueductal gray in male rats J. Comp. Neurol. 431 2001 293 310
450. S. Tsukahara, and K. Yamanouchi Sex difference in septal neurons projecting axons to midbrain central gray in rats: a combined double retrograde tracing and ER-immunohistochemical study Endocrinology 143 2002 285 294
451. Y. Tsuneoka, T. Maruyama, S. Yoshida, K. Nishimori, T. Kato, M. Numan, and K.O. Kuroda Functional, anatomical, and neurochemical differentiation of medial preoptic area subregions in relation to maternal behavior in the mouse J. Comp. Neurol. 521 2013 1633 1663
452. S. Uckert, A.J. Becker, B.O. Ness, C.G. Stief, F. Scheller, W.H. Knapp, and U. Jonas Oxytocin plasma levels in the systemic and cavernous blood of healthy males during different penile conditions World J. Urol. 20 2003 323 326
453. K. Uvnas-Moberg Role of efferent and afferent vagal nerve activity during reproduction: integrating function of oxytocin on metabolism and behaviour Psychoneuroendocrinology 19 1994 687 695
454. K. Uvnas-Moberg Oxytocin may mediate the benefits of positive social interaction and emotions Psychoneuroendocrinology 23 1998 819 835
455. C. Vaccari, S.J. Lolait, and N.L. Ostrowski Comparative distribution of vasopressin V1b and oxytocin receptor messenger ribonucleic acids in brain Endocrinology 139 1998 5015 5033
456. L.D. Van de Kar, A.D. Levy, Q. Li, and M.S. Brownfield A comparison of the oxytocin and vasopressin responses to the 5-HT1A agonist and potential anxiolytic drug alnespirone (S-20499) Pharmacol.; Biochem.; Behav. 60 1998 677 683
457. M. Van Houten, and J.R. Brawer Cytology of neurons of the hypothalamic ventromedial nucleus in the adult male rat J. Comp. Neurol. 178 1978 89 116
458. M. Van Houten, and J.R. Brawer Regional variations in glia and neuropil within the hypothalamic ventromedial nucleus J. Comp. Neurol. 179 1978 719 737
459. A.H. Veenema, and I.D. Neumann Central vasopressin and oxytocin release: regulation of complex social behaviours Prog. Brain Res. 170 2008 261 276
460. J.G. Veening Behavioural functions of the VMH in the rat: an ethological approach.; Zoology Groningen, The Netherlands 1975
461. J.G. Veening Brain and behaviour: morphological and functional aspects of the hypothalamus in the rat Eur. J. Morphol. 30 1992 53 66
462. J.G. Veening, and H.P. Barendregt The regulation of brain states by neuroactive substances distributed via the cerebrospinal fluid; a review Cereb. Fluid Res. 7 2010 1
463. J.G. Veening, and L.M. Coolen Neural activation following sexual behavior in the male and female rat brain Behav. Brain Res. 92 1998 181 193
464. J.G. Veening, and L.M. Coolen Neural mechanisms of sexual behavior in the male rat: emphasis on ejaculation-related circuits Pharmacol.; Biochem.; Behav. 2013
465. J.G. Veening, L.M. Coolen, T.R. de Jong, H.W. Joosten, S.F. de Boer, J.M. Koolhaas, and B. Olivier Do similar neural systems subserve aggressive and sexual behaviour in male rats? Insights from c-Fos and pharmacological studies Eur. J. Pharmacol. 526 2005 226 239
466. J.G. Veening, L.M. Coolen, and P.O. Gerrits Neural mechanisms of female sexual behavior in the rat; comparison with male ejaculatory control Pharmacol.; Biochem.; Behav. 2013
467. J.G. Veening, T. de Jong, and H.P. Barendregt Oxytocin-messages via the cerebrospinal fluid: behavioral effects; a review Physiol. Behav. 101 2010 193 210
468. J.G. Veening, P.O. Gerrits, and H.P. Barendregt Volume transmission of beta-endorphin via the cerebrospinal fluid; a review Fluids Barriers CNS 9 2012 16
469. J.G. Veening, and B. Olivier Intranasal administration of oxytocin: behavioral and clinical effects, a review Neurosci. Biobehav. Rev. 37 2013 1445 1465
470. J.G. Veening, L.W. Swanson, W.M. Cowan, R. Nieuwenhuys, and L.M. Geeraedts The medial forebrain bundle of the rat. II. An autoradiographic study of the topography of the major descending and ascending components J. Comp. Neurol. 206 1982 82 108
471. J. Vega Matuszczyk, A. Fernandez-Guasti, and K. Larsson Sexual orientation, proceptivity, and receptivity in the male rat as a function of neonatal hormonal manipulation Horm. Behav. 22 1988 362 378
472. F. Veronneau-Longueville, O. Rampin, M.J. Freund-Mercier, Y. Tang, A. Calas, L. Marson, K.E. McKenna, M.E. Stoeckel, G. Benoit, and F. Giuliano Oxytocinergic innervation of autonomic nuclei controlling penile erection in the rat Neuroscience 93 1999 1437 1447
473. A. Vicentic, Q. Li, G. Battaglia, and L.D. Van de Kar WAY-100635 inhibits 8-OH-DPAT-stimulated oxytocin, ACTH and corticosterone, but not prolactin secretion Eur. J. Pharmacol. 346 1998 261 266
474. F.C. Vilela, and A. Giusti-Paiva Glucocorticoids disrupt neuroendocrine and behavioral responses during lactation Endocrinology 152 2011 4838 4845
475. C.K. Wagner, and L.G. Clemens Neurophysin-containing pathway from the paraventricular nucleus of the hypothalamus to a sexually dimorphic motor nucleus in lumbar spinal cord J. Comp. Neurol. 336 1993 106 116
476. M. Waldherr, and I.D. Neumann Centrally released oxytocin mediates mating-induced anxiolysis in male rats Proc. Natl. Acad. Sci. USA 104 2007 16681 16684
477. M.D. Waldinger History of premature ejaculation E.A. Jannini, C.G. McMahon, M.D. Ealdinger, Premature Ejaculation. From Etiology to Diagnosis and Treatment 2013 Springer-Verlag, Italia Italia 5 24
478. M.D. Waldinger Premature ejaculation: different pathophysiologies and etiologies determine its treatment J. Sex Marital Ther. 34 2008 1 13
479. Waldinger, M.D.; 2014. Ejaculatio praecox, erectio praecox, and detumescentia praecox as symptoms of a hypertonic state in lifelong premature ejaculation: a new hypothesis. Pharmacol. Biochem. Behav. 121, 189-194, http://dx.doi.org/10.1016/j.pbb.2013.12.004.
480. Z.X. Wang, Y. Liu, L.J. Young, and T.R. Insel Hypothalamic vasopressin gene expression increases in both males and females postpartum in a biparental rodent J Neuroendocrinol. 12 2000 111 120
481. Y.F. Wang, and K. Hamilton Chronic vs. acute interactions between supraoptic oxytocin neurons and astrocytes during lactation: role of glial fibrillary acidic protein plasticity Sci. World J. 9 2009 1308 1320
482. Y.F. Wang, and G.I. Hatton Astrocytic plasticity and patterned oxytocin neuronal activity: dynamic interactions J. Neurosci.: Off. J. Soc. Neurosci. 29 2009 1743 1754
483. Y.F. Wang, H. Negoro, and T. Higuchi Lesions of hypothalamic mammillary body desynchronise milk-ejection bursts of rat bilateral supraoptic oxytocin neurones J. Neuroendocrinol. 25 2013 67 75
484. I.L. Ward Prenatal stress feminizes and demasculinizes the behavior of males Science 175 1972 82 84
485. I.L. Ward Exogenous androgen activates female behavior in noncopulating, prenatally stressed male rats J. Comp. Physiol. Psychol. 91 1977 465 471
486. I.L. Ward, J.E. Franck, and W.R. Crowley Central progesterone induces female sexual behavior in estrogen-primed intact males rats J. Comp. Physiol. Psychol. 91 1977 1416 1423
487. O. Weisman, O. Zagoory-Sharon, and R. Feldman Oxytocin administration to parent enhances infant physiological and behavioral readiness for social engagement Biol. Psychiatry 72 2012 982 989
488. J. Weisz, and I.L. Ward Plasma testosterone and progesterone titers of pregnant rats, their male and female fetuses, and neonatal offspring Endocrinology 106 1980 306 316
489. S.R. Wersinger, M.J. Baum, and M.S. Erskine Mating-induced FOS-like immunoreactivity in the rat forebrain: a sex comparison and a dimorphic effect of pelvic nerve transection J. Neuroendocrinol. 5 1993 557 568
490. R.E. Whalen, B.A. Gladue, and K.L. Olsen Lordotic behavior in male rats: genetic and hormonal regulation of sexual differentiation Horm. Behav. 20 1986 73 82
491. B. Whipple, and B.R. Komisaruk Brain (PET) responses to vaginal-cervical self-stimulation in women with complete spinal cord injury: preliminary findings J. Sex Marital Ther. 28 2002 79 86
492. J.B. Whitney, and L.R. Herrenkohl Effects of anterior hypothalamic lesions on the sexual behavior of prenatally-stressed male rats Physiol. Behavior. 19 1977 167 169
493. J.F. Whitney Effect of medial preoptic lesions on sexual behavior of female rats is determined by test situation Behav. Neurosci. 100 1986 230 235
494. J.R. Williams, C.S. Carter, and T. Insel Partner preference development in female prairie voles is facilitated by mating or the central infusion of oxytocin Ann. N. Y. Acad. Sci. 652 1992 487 489
495. J.R. Williams, K.C. Catania, and C.S Carter Development of partner preferences in female prairie voles (Microtus ochrogaster): the role of social and sexual experience 26 1992 339 349 Horm. Behav. 26 1992 339 349
496. L.A. Wilson, C.P. Wayman, and V.M. Jackson Neuropeptide modulation of a lumbar spinal reflex: potential implications for female sexual function J. Sex. Med. 6 2009 947 957
497. J.T. Winslow, and T.R. Insel Social status in pairs of male squirrel monkeys determines the behavioral response to central oxytocin administration J. Neurosci.: Off. J. Soc. Neurosci. 11 1991 2032 2038
498. D.M. Witt, C.S. Carter, and D.M. Walton Central and peripheral effects of oxytocin administration in prairie voles (Microtus ochrogaster) Pharmacol.; Biochem. Behav. 37 1990 63 69
499. D.M. Witt, and T.R. Insel A selective oxytocin antagonist attenuates progesterone facilitation of female sexual behavior Endocrinology 128 1991 3269 3276
500. D.M. Witt, and T.R. Insel Central oxytocin antagonism decreases female reproductive behavior Ann. N. Y. Acad. Sci. 652 1992 445 447
501. D.M. Witt, and T.R. Insel Increased Fos expression in oxytocin neurons following masculine sexual behavior J. Neuroendocrinol. 6 1994 13 18
502. M.J. Woller, M.E. Sosa, Y. Chiang, S.L. Prudom, P. Keelty, J.E. Moore, and T.E. Ziegler Differential hypothalamic secretion of neurocrines in male common marmosets: parental experience effects? J. Neuroendocrinol. 24 2012 413 421
503. B. Woodside, R. Budin, M.K. Wellman, and A. Abizaid Many mouths to feed: the control of food intake during lactation Front. Neuroendocrinol. 33 2012 301 314
504. T.J. Wu, A.Z. Segal, G.M. Miller, M.J. Gibson, and A.J. Silverman FOS expression in gonadotropin-releasing hormone neurons: enhancement by steroid treatment and mating Endocrinology 131 1992 2045 2050
505. M. Yanagimoto, K. Honda, Y. Goto, and H. Negoro Afferents originating from the dorsal penile nerve excite oxytocin cells in the hypothalamic paraventricular nucleus of the rat Brain Res. 733 1996 292 296
506. S.P. Yang, and J.L. Voogt Mating-activated nitric oxide-producing neurons in specific brain regions in the female rat Brain Res. 950 2002 79 87
507. L.J. Young, A.Z. Murphy Young, and E.A. Hammock Anatomy and neurochemistry of the pair bond J. Comp. Neurol. 493 2005 51 57
508. W.S. Young 3rd, E. Shepard, J. Amico, L. Hennighausen, K.U. Wagner, M.E. LaMarca, C. McKinney, and E.I. Ginns Deficiency in mouse oxytocin prevents milk ejection, but not fertility or parturition J. Neuroendocrinol. 8 1996 847 853
509. G.Z. Yu, H. Kaba, F. Okutani, S. Takahashi, and T. Higuchi The olfactory bulb: a critical site of action for oxytocin in the induction of maternal behaviour in the rat Neuroscience 72 1996 1083 1088
510. G.Z. Yu, H. Kaba, F. Okutani, S. Takahashi, T. Higuchi, and K. Seto The action of oxytocin originating in the hypothalamic paraventricular nucleus on mitral and granule cells in the rat main olfactory bulb Neuroscience 72 1996 1073 1082
511. O. Zagoory-Sharon, M. Schroeder, A. Levine, T.H. Moran, and A. Weller Adaptation to lactation in OLETF rats lacking CCK-1 receptors: body weight, fat tissues, leptin and oxytocin Int. J. Obes. 32 2008 1211 1221
512. M.R. Zellner, D.F. Watt, M. Solms, and J. Panksepp Affective neuroscientific and neuropsychoanalytic approaches to two intractable psychiatric problems: why depression feels so bad and what addicts really want Neurosci. Biobehav. Rev. 35 2011 2000 2008
513. X. Zhang, G. Leng, and J. Feng Coherent peptide-mediated activity in a neuronal network controlled by subcellular signaling pathway: experiments and modeling J. Biotechnol. 149 2010 215 225
514. X.H. Zhang, S. Filippi, L. Vignozzi, A. Morelli, R. Mancina, M. Luconi, S. Donati, M. Marini, G.B. Vannelli, G. Forti, and M. Maggi Identification, localization and functional in vitro and in vivo activity of oxytocin receptor in the rat penis J. Endocrinol. 184 2005 567 576
515. Y. Zhang, T.S. Gray, D.N. D'Souza, G.A. Carrasco, K.J. Damjanoska, B. Dudas, F. Garcia, G.M. Zainelli, N.R. Sullivan Hanley, G. Battaglia, N.A. Muma, and L.D. Van de Kar Desensitization of 5-HT1A receptors by 5-HT2A receptors in neuroendocrine neurons in vivo J. Pharmacol. Exp. Ther. 310 2004 59 66