History of premature ejaculation

Premature Ejaculation: From Etiology to Diagnosis and Treatment

Volumn , Issue , 2013, Pages 5-24

  Waldinger, Marcel D ^a,b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b HAGA HOSPITAL   (Netherlands)

Author keywords

5 HT; 5 HT transporter; Abraham; Acquired PE; Animal research; Citalopram; Classification; Clomipramine; Dapoxetine; Definition; DNA; Ejaculatio ante portas; Ferenczi; Fluoxetine; Genetics; Gross; Hirschfeld; IELT; Krafft Ebing; Lifelong PE; Masters Johnson; Monoamine oxydase inhibitors; Natural variable PE; Neurobiology; Neuroleptics; Paroxetine; Praejaculin; Premature ejaculation; Promonta; Psycho analysis; Psychopharmacology; Psychosomatics; Schapiro; Semans; Serotonin; Sertraline; SSRI; Stopwatch; Subjective PE; Testifortan; Variable PE; Wistar rat

Indexed keywords

EID: 84897068744     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-88-470-2646-9_2     Document Type: Chapter

References (109)

1. Ehrentheil OF (1974) A case of premature ejaculation in Greek mythology. J Sex Res 10:128-131
2. Waldinger MD (1997) Introduction: primary premature ejaculation. In: Waldinger MD (ed) When seconds count. Selective serotonin reuptake inhibitors and ejaculation, Utrecht, pp 11-27
3. Gross S (1887) Practical treatise on impotence and sterility. YJ Pentland, Edinburgh
4. Krafft-Ebing RF (1901) Psychopathia sexualis, 11th edn. Enke, Stuttgart
5. Waldinger MD (2004) Lifelong premature ejaculation: from authority-based to evidencebased medicine. Brit J Urol Int 93:201-207
6. Abraham K (1917) Über Ejaculatio Praecox. Zeitschr Aerztliche Psychoanalyse 4:171-186
7. Stekel W (1927) Impotence in the male. The psychic disorders of sexual function in the male. Boni & Liveright Publ Corp, New York, 2:22-60
8. Schapiro B (1943) Premature ejaculation: a review of 1130 cases. J Urol 50:374-379
9. Godpodinoff ML (1989) Premature ejaculation. Clinical subgroups and etiology. J Sex Marital Ther 15:130-134
10. Masters WH, Johnson VE (1970) Premature ejaculation. In: Masters WH, Johnson VE (eds) Human sexual inadequacy. Little, Brown and Co, Boston
11. Waldinger MD, Berendsen HHG, Blok BFM, Olivier B, Holstege G (1998) Premature ejaculation and serotonergic antidepressants-induced delayed ejaculation: the involvement of the serotonergic system. Behav Brain Res 92:111-118
12. Waldinger MD, Rietschel M, Nothen MM, Hengeveld MW, Olivier B (1998) Familial occurrence of primary premature ejaculation. Psychiatr Gen 8:37-40
13. Waldinger MD (2002) The neurobiological approach to premature ejaculation (review). J Urol 168:2359-2367
14. Assalian P (1994) Premature ejaculation: is it really psychogenic?. J Sex Educ Ther 20(1):1-4
15. Janssen PK, Bakker SC, Rethelyi J, Zwinderman AH, Touw DJ, Olivier B, Waldinger MD (2009) Serotonin transporter promoter region (5-HTTLPR) polymorphism is associated with the intravaginal ejaculation latency time in Dutch men with lifelong premature ejaculation. J Sex Med 6(1):276-284
16. Jern P, Santilla P, Witting K, Harlaar N, Johansson A, von der Pahlen B et al (2007) Premature and delayed ejaculation: genetic and environmental effects in a population-based sample of Finnish twins. J Sex Med 4:1739-1749
17. Santilla P, Jern P, Westberg L, Walum H, Pedersen CT, Eriksson E, Kenneth Sandnabba N (2010) The dopamine transporter gene (DAT1) polymorphism is associated with premature ejaculation. J Sex Med 7:1538-1546
18. Pryor JL, Althof SE, Steidle C, Rosen RC, Hellstrom WJ, Shabsigh R, Miloslavsky M (2006) Dapoxetine study group. Efficacy and tolerability of dapoxetine in treatment of premature ejaculation: an integrated analysis of two double-blind, randomised controlled trials. Lancet 368:929-937
19. Waldinger MD (2010) Opwindend onderzoek: de ontwikkeling van de seksuele psychofarmacologie. [oratie]. Universities utrecht, pp 1-28.
20. Dose R, Herrn R. Verloren (1933) Bibliothek und Archiv des Instituts für Sexualwissenschaft in Berlin. In: Zeitschrift für Bibliothekswesen und Bibliographie Sonderhefte. Vittorio Klostermann, Frankfurt am Main 2006. Sonderheft 88:37-51
21. Hirschfeld M, Schapiro B (1927) Testifortan. Therapie der Potenzstorungen (Prospekt). Chemische Fabrik Promonta G.m.b. H, Hamburg
22. Schapiro B (1932) Präjaculin. Kombiniertes Epiphysen-Präparat gegen Reizzustände am Genitale und Hypererotismus. Chemische Fabrik Promonta G.m.b.H, Hamburg
23. Eaton H (1973) Clomipramine in the treatment of premature ejaculation. J Int Med Res 1:432-434
24. Virag R (1982) Intracavernous injection of papaverine for erection failure. Letter to the Editor. Lancet 2:938
25. Ahlenius S, Larsson K, Svensson L (1980) Further evidence for an inhibitory role of central 5-HT in male rat sexual behavior. Psychopharmacology 68:217-220
26. Mos J, Van Logten J, Bloetjes K, Olivier B (1991) The effects of idazoxan and 8-OH-DPAT on sexual behaviour and associated ultrasonic vocalisations in the rat. Neurosci Biobehav Rev 15:505-515
27. Haensel SM, Mos J, Olivier B, Slob AK (1991) Sex behavior of male and female wistar rats affected by the serotonin agonist 8-OH-DPAT. Pharmacol Biochem Behav 40:221-228
28. Gower AJ, Berendsen HH, Broekkamp CL (1986) Antagonism of drug-induced yawning and penile erections in rats. Eur J Pharmacol 122:239-244
29. Coolen LM, Peters HJ, Veening JG (1996) Fos immunoreactivity in the rat brain following consummatory elements of sexual behavior: a sex comparison. Brain Res 738:67-82
30. Waldinger MD, Hengeveld MW, Zwinderman AH (1994) Paroxetine treatment of premature ejaculation: a double-blind, randomized, placebo-controlled study. Am J Psychiatry 151:1377-1379
31. Waldinger MD, Zwinderman AH, Schweitzer DH, Olivier B (2004) Relevance of methodological design for the interpretation of efficacy of drug treatment of premature ejaculation: a systematic review and meta-Analysis. Int J Impotence Research 16:369-381
32. Goldstein I, Lue TF, Padma-Nathan H, Rosen RC, Steers WD, Wicker PA (1998) Oral sildenafil in the treatment of erectile dysfunction. Sildenafil study group. N Engl J Med 338:1397-1404
33. Chapter Ferenczi S, (1955) Chapter XXIII. The effect on women of premature ejaculation in men. In: Balint M (ed) Final contributions to the problems and methods of psychoanalysis. The Hogarth Press, London, pp 291-294
34. Embiricos A (1950) Un cas de nevrose obsessionnelle avec ejaculations precosec. Revue Francaise de Psychoanalyse 14:331-366
35. Waldinger MD (2006) The need for a revival of psychoanalytic investigations into premature ejaculation. J Mens Health Gend 3:390-396
36. Semans JH (1956) Premature ejaculation: new approach. South Med J 49:353
37. Rowland DL, Haensel SM, Blom JHM, Slob AK (1993) Penile sensitivity in men with premature ejaculation and erectile dysfunction. J Sex Marital Ther 19:189
38. Xin ZC, Chung WS, Choi YD, Seong DH, Choi YJ, Choi HK (1996) Penile sensitivity in patients with primary premature ejaculation. J Urol 156:979
39. Paick JS, Jeong H, Park MS (1998) Penile sensitivity in men with premature ejaculation. Int J Impot Res 10:247
40. Ince L (1973) Behavior modification of sexual disorders. Am J Psychother 17:446
41. Wish P (1975) The use of imagery-based techniques in the treatment of sexual dysfunction. Couns Psychol 5:52
42. Mosher DL (1979) Awareness in Gestalt sex therapy. J Sex Marital Ther 5:41
43. Waltzlawick P, Weakland JH, Fisch R (1974) Change: principles of problem formation and problem resolution. Norton Publishing, New York
44. Zeiss RA, Christensen A, Levine AG (1978)Treatment for premature ejaculation through male-only groups. J Sex Marital Ther 4:139
45. Kaplan HS, Kohl RN, Pomeroy WB, Offit AK, Hogan B (1974) Group treatment of premature ejaculation. Arch Sex Behav 3:443
46. Lowe CJ, Mikulas WL (1975) Use of written material in learning self control of premature ejaculation. Psychol Rep 3(7):295
47. De Amicis LA, Goldberg DC, LoPiccolo J, Friedman J, Davies L (1985) Clinical follow-up of couples treated for sexual dysfunction. Arch Sex Behav 1(4):467
48. Hawton K, Catalan J (1986) Prognostic factors in sex therapy. Behav Res Ther 2(4):377
49. Kaplan HS (1974) The new sex therapy: active treatment of sexual dysfunctions. Brunner, New York
50. Cooper AJ, Magnus RV (1984) A clinical trial of the beta blocker propranolol in premature ejaculation. J Psychosom Res 2(8):331
51. Spiess WF, Geer JH, O'Donohue WT (1984) Premature ejaculation: investigation of factors in ejaculatory latency. J Abnorm Psychol 9(3):242
52. Strassberg DS, Mahoney JM, Schaugaard M, Hale VE (1990) The role of anxiety in premature ejaculation: a psychophysiological model. Arch Sex Behav 1(9):251
53. Obler M (1973) Systematic desensitisation in sexual disorders. J Behav Ther Exp Psychiatr 4:93-101
54. Strassberg DS, Kelly MP, Carroll C, Kircher JC (1987) The psychophysiological nature of premature ejaculation. Arch Sex Behav 1(6):327
55. LoPiccolo J (1978) Direct treatment of sexual dysfunction in the couple, In: Money J, Musaph H (eds) Handbook of sexology: selected syndromes and therapy, vol 5. Elsevier, New York, pp 1227-1244
56. Kilmann PR, Auerbach R (1979) Treatments of premature ejaculation and psychogenic impotence a critical review of the literature. Arch Sex Behav 8:81
57. Trudel G, Proulx S (1987) Treatment of premature ejaculation by bibliotherapy: an experimental study. Sex Marital Ther 2:163
58. Zeiss RA, Christensen A, Levine AG (1978) Treatment for premature ejaculation through male-only groups. J Sex Marital Ther 4:139
59. Schover LR, Friedman JM, Weiler SJ, Heiman JR, LoPiccolo J (1982) Multiaxial problemoriented system for sexual dysfunctions: an alternative to DSM-III. Arch Gen Psychiatr 3(9):614
60. Fanciullaci F, Colpi GM, Beretta G, Zanollo A (1988) Cortical evoked potentials in subjects with true premature ejaculation. Andrologia 2:326
61. Colpi GM, Fanciullaci F, Beretta G, Negri L, Zanollo A (1986) Evoked sacral potentials in subjects with true premature ejaculation. Andrologia 1(8):583
62. Segraves RT, Saran A, Segraves K, Maguire E (1993) Clomipramine versus placebo in the treatment of premature ejaculation: a pilot study. J Sex Marital Ther 19:198-200
63. Aycock L (1949) The medical management of premature ejaculation. J Urol 6(2):361
64. Damrau F (1963) Premature ejaculation: use of ethyl aminobenzoate to prolong coitus. J Urol 8(9):936
65. Shilon M, Paz GF, Hommonai ZT (1984) The use of phenoxybenzamine treatment in premature ejaculation. Fertil Steril 4(2):659
66. Hommonai ZT, Shilon M, Paz GF (1984) Phenoxybenzamine: an effective male contraceptive pill. Contraception 2(9):479
67. Beretta G, Chelo E, Fanciullacci F, Zanolla A (1986) Effect of an alpha-blocking agent (phenoxybenzamine) in the management of premature ejaculation. Acta Eur Fertil 1(7):43
68. Cavallini G (1995) Alpha-1 blockade pharmacotherapy in primitive psychogenic premature ejaculation resistant to psychotherapy. Eur Urol 2(8):126
69. Singh H (1961) A case of inhibition of ejaculation as a side effect of Mellaril. Am J Psychiatry 11(7):1041
70. Freyhan FA (1961) Loss of ejaculation during mellaril treatment. Am J Psychiatry 11(8):171
71. Ditman KS (1964) Inhibition of ejaculation by chlorprothixene. Am J Psychiatry 12:1004
72. Bennett D (1961) Treatment of ejaculatio praecox with monoamine oxidase inhibitors (letter to the editor). Lancet 2:1309
73. Rapp MS (1979) Two cases of ejaculatory impairment related to phenelzine. Am J Psychiatry 13(6):1200
74. Goodman RE (1980) An assessment of clomipramine (anafranil) in the treatment of premature ejaculation. J Int Med Res 8(suppl):53
75. Porto R (1981) Essai en double aveugle de la clomipramine dans l'ejaculation prematuree. Med Hyg 3(9):1249
76. Girgis SM, El-Haggen S, El-Hermouzy S (1982) A double-blind trial of clomipramine in premature ejaculation. Andrologia 1(4):364
77. Assalian P (1988) Clomipramine in the treatment of premature ejaculation. J Sex Res 2(4):213
78. Althof SE (1995) Pharmacologic treatment of rapid ejaculation. Psychiatr Clin N Am 1(8):85
79. Althof SE, Levine SB, Corty EW, Risen CB, Stern EB, Kurit DM (1995) A double-blind crossover trial of clomipramine for rapid ejaculation in 15 couples. J Clin Psychiatry 5(6):402
80. Haensel SM, Rowland DL, Kallan KTHK, Slob AK (1996) Clomipramine and sexual function in men with premature ejaculation and controls. J Urol 15(6):1310
81. Zegerius L, Waldinger MD (1995) DSM-IV: de ondergang van het begrip ''organisch''. Tijdschrift voor Psychiatrie 37:553-567
82. Waldinger MD, Hengeveld MW, Zwinderman AH (1997) Ejaculation-retarding properties of paroxetine in patients with primary premature ejaculation: a double-blind, randomized, dose-response study. Br J Urol 7(9):592
83. Ludovico GM, Corvace A, Pagliarulo G, Cirillo-Marucco E, Marano A, Pagliarulo A (1996) Paroxetine in the treatment of premature ejaculation. Br J Urol 7(7):881
84. McMahon CG, Touma K (1999) Treatment of premature ejaculation with paroxetine hydrochloride as needed: 2 single-blind placebo controlled crossover studies. J Urol 16(1):1826
85. Mendels J, Camera A, Sikes C (1995) Sertraline treatment for premature ejaculation. J Clin Psychopharmacol 1(5):341
86. McMahon CG (1998) Treatment of premature ejaculation with sertraline hydrochloride: a single-blind placebo controlled crossover study. J Urol 15(9):1935
87. Kim SW, Paick JS (1999) Short-Term analysis of the effects of as needed use of sertraline at 5 PM for the treatment of premature ejaculation. Urology 5(4):544
88. Kara H, Aydin S, Agargün MY, Odabuas O;, Yilmiz Y (1996) The efficacy of fluoxetine in the treatment of premature ejaculation: a double-blind, placebo controlled study. J Urol 15(6):1631
89. Lee HS, Song DH, Kim CH, Choi HK (1996) An open clinical trial of fluoxetine in the treatment of premature ejaculation. J Clin Psychopharmacol 16(5):379-382
90. Haensel SM, Klem TM, Hop WC, Slob AK (1998) Fluoxetine and premature ejaculation: a double-blind, crossover, placebo-controlled study. J Clin Psychopharmacol 18:72
91. Tanner BA (1973) Two case reports on the modification of the ejaculatory response with the squeeze technique. Psychother Theory Res Pract 10:297
92. Waldinger MD, van de Plas Pattij T, Oorschot RV, Coolen LM, Veening JG, van De Plas Pattij T, Oorschot RV, Coolen LM, Veening JG et al (2002) The selective serotonin re-Take inhibitors fluvoxamine and paroxetine differ in sexual inhibitory effects after chronic treatment. Psychopharmacology 160:283
93. Mos J, Mollet I, Tolboom JTBM, Waldinger MD, Olivier B (1999) A comparison of the effects of different serotonin reuptake blockers on sexual behaviour of the male rat. Eur Neuropsychopharmacol 9:123-135
94. de Jong TR, Veening JG, Olivier B, Waldinger MD (2007) Oxytocin involvement in SSRIinduced delayed ejaculation: a review of animal studies. J Sex Med 4:14-28
95. Cantor JM, Binik YM, Pfaus JG (1999) Chronic fluoxetine inhibits sexual behavior in the male rat: reversal with oxytocin. Psychopharmacology 144:355
96. Li Q, Levy AD, Cabrera TM, Brownfield MS, Battaglia G, van de Kar LD (1993) Longterm fluoxetine, but not desipramine, inhibits the ACTH and oxytocin responses to the 5-HT1A agonist, 8-OH-DPAT, in male rats. Brain Res 630:148
97. Pattij T, de Jong T, Uitterdijk A, Waldinger MD, Veening JG, van der Graaf PH, Olivier B (2005) Individual differences in male rat ejaculatory behavior: searching for models to study ejaculation disorders. Eur J Neurosci 22:724-734
98. Pattij T, Olivier B, Waldinger MD (2005) Animal models of ejaculatory behaviour. Curr Pharm Des 11:4069-4077
99. Waldinger MD, Quinn P, Dilleen M, Mundayat R, Schweitzer DH, Boolell M (2005) A Multi-national population survey of intravaginal ejaculation latency time. J Sex Med 2:492-497
100. Waldinger MD, McIntosh J, Schweitzer DH (2009) A five-nation survey to assess the distribution of the intravaginal ejaculatory latency time among the general male population. J Sex Med 6:2888-2895
101. Waldinger MD, Hengeveld MW, Zwinderman AH, Olivier B (1998) An empirical operationalization study of DSM-IV diagnostic criteria for premature ejaculation. Int J Psychiatry Clin Prac 2:287-293
102. Waldinger MD, Schweitzer DH (2006) Changing paradigms from an historical DSM-III and DSM-IV view towards an evidence based definition of premature ejaculation. Part I: Validity of DSM-IV-TR. J Sex Med 3:682-692
103. McMahon CG, Althof S, Waldinger MD, Porst H, Dean J, Sharlip I, Adaikan PG, Becher E, Broderick GA, Buvat J, Dabees K, Giraldi A, Giuliano F, Hellstrom WJ, Incrocci L, Laan E, Meuleman E, Perelman MA, Rosen R, Rowland D, Segraves R (2008) An evidence-based definition of lifelong premature ejaculation: report of the international society for sexual medicine (ISSM) ad hoc committee for the definition of premature ejaculation. J Sex Med 5:1590-1606
104. Althof SE, Abdo CHN, Dean J, Hackett G, McCabe M, McMahon CG, Rosen RC, Sadovsky R, Waldinger MD, Becher E, Broderick GA, Buvat J, Goldstein I, El-Meliegy AI, Giuliano F, Hellstrom WJG, Incrocci L, D M, Jannini E, Park K, Parish S, Porst H, Rowland D, Segraves R, Sharlip I, Simonelli C, Tan HM (2010) International society for sexual medicine's guidelines for the diagnosis and treatment of premature ejaculation. J Sex Med 7:2947-2969
105. Waldinger MD, Schweitzer DH (2008) The use of old and recent DSM definitions of premature ejaculation in observational studies: a contribution to the present debate for a new classification of PE in the DSM-V. J Sex Med 5:1079-1087
106. Serefoglu EC, Cimen HI, Atmaca AF, Balbay MD (2010) The distribution of patients who seek treatment for the complaint of ejaculating prematurely according to the four premature ejaculation syndromes. J Sex Med 7:810-815
107. Serefoglu EC, Yaman O, Cayan S, Asci R, Orhan I, Usta MF, Ekmekcioglu O, Kendirci M, Semerci B, Kadioglu A (2011) The comparison of premature ejaculation assessment questionnaires and their sensitivity for the four premature ejaculation syndromes: results from the Turkish society of andrology sexual health survey. J Sex Med 8:1177-1185
108. Jern P, Santilla P, Johansson A, Varjonen M, Witting K, Algars M et al (2008) Indicators of premature ejaculation and their associations with sexual distress in a population-based sample of young twins and their siblings. J Sex Med 5:2191-2201
109. Buvat J, Tesfaye F, Rothman M, Rivas D, Giuliano F (2009) Dapoxetine for the treatment of premature ejaculation: results from a randomized, double-blind, placebo-controlled phase III trial in 22 countries. Eur Urol 55:957-967