Inhibition of ejaculation by the non-peptide oxytocin receptor antagonist GSK557296: A multi-level site of action

British Journal of Pharmacology

Volumn 169, Issue 7, 2013, Pages 1477-1485

  Clément, Pierre ^a,b   Bernabé, Jacques ^a,b   Compagnie, Sandrine ^a,b   Alexandre, Laurent ^a   McCallum, Stewart ^c   Giuliano, François ^a,b,d  

^a Pelvipharm Laboratories   (France)

^b LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^c GLAXOSMITHKLINE   (United States)

^d RAYMOND POINCARÉ HOSPITAL   (France)

Author keywords

7 OH DPAT; bulbospongiosus muscle; intracerebroventricular; intrathecal; premature ejaculation; seminal vesicle

Indexed keywords

2 DIPROPYLAMINO 7 HYDROXYTETRALIN; EPELSIBAN; OXYTOCIN RECEPTOR; PLACEBO;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BULBOSPONGIOSUS MUSCLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG RECEPTOR BINDING; DRUG SAFETY; DRUG STRUCTURE; DRUG TOLERABILITY; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; MALE; MUSCLE; NONHUMAN; PREMATURE EJACULATION; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SEMINAL VESICLE;

7-OH-DPAT; BULBOSPONGIOSUS MUSCLE; INTRACEREBROVENTRICULAR; INTRATHECAL; PREMATURE EJACULATION; SEMINAL VESICLE;

ANIMALS; BRAIN; DIKETOPIPERAZINES; DOSE-RESPONSE RELATIONSHIP, DRUG; EJACULATION; MALE; MORPHOLINES; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; RATS; RATS, WISTAR; RECEPTORS, OXYTOCIN; TETRAHYDRONAPHTHALENES;

EID: 84880276230     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12198     Document Type: Article

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