Ventral premammillary nucleus as a critical sensory relay to the maternal aggression network

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 35, 2013, Pages 14438-14443

  Motta, Simone C ^a   Guimarães, Cibele Carla ^a   Furigo, Isadora Clivatti ^a   Sukikara, Marcia Harumi ^b   Baldo, Marcus V C ^c   Lonstein, Joseph S ^d   Canteras, Newton S ^a  

^a Departamento de Anatomia   (Brazil)

^b MASTERS AND DOCTORAL PROGRAMS IN PHYSICAL THERAPY   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRESSION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; IMMUNOHISTOCHEMISTRY; LATERAL HYPOTHALAMUS; MALE; NONHUMAN; POSTERIOR HYPOTHALAMUS; PREOPTIC NUCLEUS; PRIORITY JOURNAL; RAT; THALAMUS VENTRAL NUCLEUS;

AGGRESSION; ANIMALS; BEHAVIOR, ANIMAL; FEMALE; MALE; RATS; RATS, LONG-EVANS; VENTROMEDIAL HYPOTHALAMIC NUCLEUS;

EID: 84883344452     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1305581110     Document Type: Article

References (42)

1. Lonstein JS, Gammie SC (2002) Sensory, hormonal, and neural control of maternal aggression in laboratory rodents. Neurosci Biobehav Rev 26(8):869-888.
2. Ferreira A, Hansen S (1986) Sensory control of maternal aggression in Rattus norvegicus. J Comp Psychol 100(2):173-177.
3. Mayer AD, et al. (1987) Mammary stimulation and maternal aggression in rodents: Thelectomy fails to reduce pre- or postpartum aggression in rats. Horm Behav 21(4): 501-510.
4. Mayer AD, Rosenblatt JS (1987) Hormonal factors influence the onset of maternal aggression in laboratory rats. Horm Behav 21(2):253-267.
5. Mayer AD, Rosenblatt JS (1993) Peripheral olfactory deafferentation of the primary olfactory system in rats using ZnSO4 nasal spray with special reference to maternal behavior. Physiol Behav 53(3):587-592.
6. Kolunie JM, Stern JM (1995) Maternal aggression in rats: effects of olfactory bulbectomy, ZnSO4-induced anosmia, and vomeronasal organ removal. Horm Behav 29(4):492-518.
7. Gammie SC, Lonstein JS (2006) Maternal aggression. Biology of Aggression, ed Nelson RJ (Oxford Univ Press, New York), pp 250-274.
8. Stern JM, Kolunie JM (1991) Trigeminal lesions and maternal behavior in Norway rats: I. Effects of cutaneous rostral snout denervation on maintenance of nurturance and maternal aggression. Behav Neurosci 105(6):984-997.
9. Hansen S (1989) Medial hypothalamic involvement in maternal aggression of rats. Behav Neurosci 103(5):1035-1046.
10. Roeling TA, et al. (1994) Efferent connections of the hypothalamic "aggression area" in the rat. Neuroscience 59(4):1001-1024.
11. Dong HW, Swanson LW (2006) Projections from bed nuclei of the stria terminalis, dorsomedial nucleus: Implications for cerebral hemisphere integration of neuroendocrine, autonomic, and drinking responses. J Comp Neurol 494(1):75-107.
12. Dong HW, Swanson LW (2006) Projections from bed nuclei of the stria terminalis, magnocellular nucleus: Implications for cerebral hemisphere regulation of micturition, defecation, and penile erection. J Comp Neurol 494(1):108-141.
13. Dong HW, Swanson LW (2006) Projections from bed nuclei of the stria terminalis, anteromedial area: Cerebral hemisphere integration of neuroendocrine, autonomic, and behavioral aspects of energy balance. J Comp Neurol 494(1):142-178.
14. Kovács KJ (2008) Measurement of immediate-early gene activation-c-fos and beyond. J Neuroendocrinol 20(6):665-672.
15. Hasen NS, Gammie SC (2006) Maternal aggression: New insights from Egr-1. Brain Res 1108(1):147-156.
16. Hasen NS, Gammie SC (2009) Trpc2 gene impacts on maternal aggression, accessory olfactory bulb anatomy and brain activity. Genes Brain Behav 8(7):639-649.
17. Scalia F, Winans SS (1975) The differential projections of the olfactory bulb and accessory olfactory bulb in mammals. J Comp Neurol 161(1):31-55.
18. Canteras NS, Simerly RB, Swanson LW (1995) Organization of projections from the medial nucleus of the amygdala: A PHAL study in the rat. J Comp Neurol 360(2): 213-245.
19. Luiten PG, Koolhaas JM, de Boer S, Koopmans SJ (1985) The cortico-medial amygdala in the central nervous system organization of agonistic behavior. Brain Res 332(2): 283-297.
20. Spiteri T, et al. (2010) The role of the estrogen receptor alpha in the medial amygdala and ventromedial nucleus of the hypothalamus in social recognition, anxiety and aggression. Behav Brain Res 210(2):211-220.
21. Canteras NS, Simerly RB, Swanson LW (1992) Connections of the posterior nucleus of the amygdala. J Comp Neurol 324(2):143-179.
22. Haller J, Millar S, Kruk MR (1998) Mineralocorticoid receptor blockade inhibits aggressive behaviour in male rats. Stress 2(3):201-207.
23. Hasen NS, Gammie SC (2005) Differential fos activation in virgin and lactating mice in response to an intruder. Physiol Behav 84(5):681-695.
24. Canteras NS, Simerly RB, Swanson LW (1994) Organization of projections from the ventromedial nucleus of the hypothalamus: a Phaseolus vulgaris-leucoagglutinin study in the rat. J Comp Neurol 348(1):41-79.
25. Woulfe JM, Hrycyshyn AW, Flumerfelt BA (1988) Collateral axonal projections from the A1 noradrenergic cell group to the paraventricular nucleus and bed nucleus of the stria terminalis in the rat. Exp Neurol 102(1):121-124.
26. Morilak DA, et al. (2005) Role of brain norepinephrine in the behavioral response to stress. Prog Neuropsychopharmacol Biol Psychiatry 29(8):1214-1224.
27. Cavalcante JC, Bittencourt JC, Elias CF (2006) Female odors stimulate CART neurons in the ventral premammillary nucleus of male rats. Physiol Behav 88(1-2):160-166.
28. Leshan RL, et al. (2009) Direct innervation of GnRH neurons by metabolic- and sexual odorant-sensing leptin receptor neurons in the hypothalamic ventral premammillary nucleus. J Neurosci 29(10):3138-3147.
29. Vincent SR, Kimura H (1992) Histochemical mapping of nitric oxide synthase in the rat brain. Neuroscience 46(4):755-784.
30. Garthwaite J (2008) Concepts of neural nitric oxide-mediated transmission. Eur J Neurosci 27(11):2783-2802.
31. Gammie SC, Nelson RJ (1999) Maternal aggression is reduced in neuronal nitric oxide synthase-deficient mice. J Neurosci 19(18):8027-8035.
32. Canteras NS, Simerly RB, Swanson LW (1992) Projections of the ventral premammillary nucleus. J Comp Neurol 324(2):195-212.
33. Numan M (2006) Hypothalamic neural circuits regulating maternal responsiveness toward infants. Behav Cogn Neurosci Rev 5(4):163-190.
34. Simerly RB, Swanson LW (1986) The organization of neural inputs to the medial preoptic nucleus of the rat. J Comp Neurol 246(3):312-342.
35. Simerly RB, Swanson LW (1988) Projections of the medial preoptic nucleus: A Phaseolus vulgaris leucoagglutinin anterograde tract-tracing study in the rat. J Comp Neurol 270(2):209-242.
36. Lin D, et al. (2011) Functional identification of an aggression locus in the mouse hypothalamus. Nature 470(7333):221-226.
37. Roberts WW, Nagel J (1996) First-order projections activated by stimulation of hypothalamic sites eliciting attack and flight in rats. Behav Neurosci 110(3):509-527.
38. Factor EM, Mayer AD, Rosenblatt JS (1993) Peripeduncular nucleus lesions in the rat: I. Effects on maternal aggression, lactation, and maternal behavior during pre- and postpartum periods. Behav Neurosci 107(1):166-185.
39. Motta SC, et al. (2009) Dissecting the brain's fear system reveals the hypothalamus is critical for responding in subordinate conspecific intruders. Proc Natl Acad Sci USA 106(12):4870-4875.
40. Hill JW, Elmquist JK, Elias CF (2008) Hypothalamic pathways linking energy balance and reproduction. Am J Physiol Endocrinol Metab 294(5):E827-E832.
41. Slamberová R, Bar N, Vathy I (2003) Long-term effects of prenatal morphine exposure on maternal behaviors differ from the effects of direct chronic morphine treatment. Dev Psychobiol 43(4):281-289.
42. Swanson LW (2004) Brain Maps: Structure of the Rat Brain. An Atlas with Printed and Electronic Templates for Data, Models, and Schematics (Elsevier, Amsterdam).