Role of oxytocin in energy metabolism

Peptides

Volumn 45, Issue , 2013, Pages 9-14

  Chaves, Valéria Ernestânia ^a   Tilelli, Cristiane Queixa ^a   Brito, Nilton Almeida ^b   Brito, Márcia Nascimento ^b  

^a FEDERAL UNIVERSITY OF SÃO JOÃO DEL REI   (Brazil)

^b STATE UNIVERSITY OF MARINGÁ   (Brazil)

Author keywords

Adipose tissue; Appetite control; Energy metabolism; Obesity; Oxytocin; Thermoregulation

Indexed keywords

OXYTOCIN; OXYTOCIN RECEPTOR; LEPTIN; PHOSPHOLIPASE C BETA;

APPETITE; BODY WEIGHT; ENERGY EXPENDITURE; ENERGY METABOLISM; FOOD INTAKE; HOMEOSTASIS; HUMAN; MYOEPITHELIUM CELL; MYOMETRIUM; OBESITY; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; THERMOREGULATION; ADIPOSE TISSUE; CYTOLOGY; DRUG EFFECTS; EATING; GENETICS; METABOLISM; NERVE CELL; PHYSIOLOGY;

RODENTIA;

ADIPOSE TISSUE; APPETITE REGULATION; BODY TEMPERATURE REGULATION; BODY WEIGHT; EATING; ENERGY METABOLISM; HOMEOSTASIS; HUMANS; LEPTIN; NEURONS; OBESITY; OXYTOCIN; PHOSPHOLIPASE C BETA; RECEPTORS, OXYTOCIN;

EID: 84877805959     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2013.04.010     Document Type: Review

References (76)

1. S. Alberi, J.J. Dreifuss, and M. Raggenbass The oxytocin-induced inward current in vagal neurons of the rat is mediated by G protein activation but not by an increase in the intracellular calcium concentration Eur J Neurosci 9 1997 2605 2612 (Pubitemid 28082950)
2. J.A. Amico, R.R. Vollmer, H.M. Cai, J.A. Miedlar, and L. Rinaman Enhanced initial and sustained intake of sucrose solution in mice with an oxytocin gene deletion Am J Physiol Regul Integr Comp Physiol 289 2005 R1798 R1806
3. R. Arletti, A. Benelli, and A. Bertolini Influence of oxytocin on feeding behavior in the rat Peptides 10 1989 89 93 (Pubitemid 19108042)
4. R. Arletti, A. Benelli, and A. Bertolini Oxytocin inhibits food and fluid intake in rats Physiol Behav 48 1990 825 830
5. D. Atasoy, J.N. Betley, H.H. Su, and S.M. Sternson Deconstruction of a neural circuit for hunger Nature 488 2012 172 177
6. N. Balthasar, L.T. Dalgaard, C.E. Lee, J. Yu, H. Funahashi, and T. Williams Divergence of melanocortin pathways in the control of food intake and energy expenditure Cell 123 2005 493 505 (Pubitemid 41546678)
7. D.G. Baskin, F. Kim, R.W. Gelling, B.J. Russell, M.W. Schwartz, and G.J. Morton A new oxytocin-saporin cytotoxin for lesioning oxytocin-receptive neurons in the rat hindbrain Endocrinology 151 2010 4207 4213
8. E. Björkstrand, M. Eriksson, and K. Uvnäs-Moberg Evidence of a peripheral and a central effect of oxytocin on pancreatic hormone release in rats Neuroendocrinology 63 1996 377 383 (Pubitemid 26117204)
9. J.E. Blevins, T.J. Eakin, J.A. Murphy, M.W. Schwartz, and D.G. Baskin Oxytocin innervation of caudal brainstem nuclei activated by cholecystokinin Brain Res 993 2003 30 41 (Pubitemid 37464580)
10. J.E. Blevins, M.W. Schwartz, and D.G. Baskin Evidence that paraventricular nucleus oxytocin neurons link hypothalamic leptin action to caudal brain stem nuclei controlling meal size Am J Physiol Regul Integr Comp Physiol 287 2004 R87 R96
11. C. Camerino Low sympathetic tone and obese phenotype in oxytocin-deficient mice Obesity 7 2009 980 984
12. B. Cannon, and J. Nedergaard Brown adipose tissue: function and physiological significance Physiol Rev 84 2004 277 359 (Pubitemid 38054374)
13. V.E. Chaves, D. Frasson, and N.H. Kawashita Several agents and pathways regulate lipolysis in adipocytes Biochimie 93 2011 1631 1640
14. V.E. Chaves, D. Frasson, M.E. Martins-Santos, R.P. Boschini, M.A. Garófalo, and W.T. Festuccia Glyceroneogenesis is reduced and glucose uptake is increased in adipose tissue from cafeteria diet-fed rats independently of tissue sympathetic innervation J Nutr 136 2006 2475 2480 (Pubitemid 44521599)
15. H.H. Dale On some physiological actions of ergot J Physiol (Lond) 34 1906 163 206
16. B.A. Danalache, J. Gutkowska, M.J. Slusarz, I. Berezowska, and M. Jankowski Oxytocin-Gly-Lys-Arg: a novel cardiomyogenic peptide PLoS ONE 5 2010 e13643
17. B. De Luca, M. Monda, S. Amaro, M.P. Pellicano, and L.A. Cioffi Lack of diet induced thermogenesis following lesions of paraventricular nucleus in rats Physiol Behav 46 1989 685 691 (Pubitemid 19268841)
18. N. Deblon, C. Veyrat-Durebex, L. Bourgoin, A. Caillon, A.L. Bussier, and S. Petrosino Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats PLoS ONE 6 9 2011 e25565
19. S. Denda, K. Takei, J. Kumamoto, M. Goto, M. Tsutsumi, and M. Denda Oxytocin is expressed in epidermal keratinocytes and released upon stimulation with adenosine 5′-[(-thio]triphosphate in vitro Exp Dermatol 21 2012 535 537
20. V. Du Vigneaud, C. Ressler, and S. Trippett The sequence of amino acids in oxytocin, with a proposal for the structure of oxytocin J Biol Chem 205 1953 949 957
21. M. Eckertova, M. Ondrejcakova, K. Krskova, S. Zorad, and D. Jezova Subchronic treatment of rats with oxytocin results in improved adipocyte differentiation and increased gene expression of factors involved in adipogenesis Br J Pharmacol 162 2011 452 463
22. J.J. Egan, J. Saltis, S.A. Wek, I.A. Simpson, and C. Londos Insulin, oxytocin and vasopressin stimulate protein kinase C activity in adipocyte plasma membranes Proc Natl Acad Sci USA 87 1990 1052 1056
23. M. Egawa, H. Yoshimatsu, and G.A. Bray Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats Am J Physiol 260 1991 R328 R334
24. H. Eriksson, P. Björgell, M. Akerlund, A. Hauksson, and P. Melin Effects of a tocolytic oxytocin analogue on lipid and carbohydrate metabolism Gynecol Obstet Invest 29 1990 97 100 (Pubitemid 20113473)
25. J.N. Fain, Y. Gokmen-Polar, and S.W. Bahouth Wortmannin converts insulin but not oxytocin from an antilipolytic to a lipolytic agent in the presence of forskolin Metabolism 46 1997 62 66 (Pubitemid 27052026)
26. R. Feldman, A. Weller, O. Zagoory-Sharon, and A. Levine Evidence for a neuroendocrinological foundation of human affiliation: plasma oxytocin levels across pregnancy and the post partum period predict mother-infant bonding Psychol Sci 18 2007 965 970
27. Z.Y. Gao, G. Drews, and J.C. Henquin Mechanism of the stimulation of insulin release by oxytocin in normal mouse islets Biochem J 276 1991 169 174
28. M. Ghamari-Langroudi, D. Srisai, and R.D. Cone Multinodal regulation of the arcuate/paraventricular nucleus circuit by leptin Proc Natl Acad Sci 108 2011 355 360
29. G. Gimpl, and F. Fahrenholz The oxytocin receptor system: structure, function and regulation Physiol Rev 81 2001 629 683 (Pubitemid 32267075)
30. B.R. Gould, and H.H. Zingg Mapping oxytocin receptor gene expression in the mouse brain and mammary gland using an oxytocin receptor-LacZ reporter mouse Neuroscience 122 2003 155 167
31. M. Gravati, M. Busnelli, E. Bulgheroni, A. Reversi, P. Spaiardi, and M. Parenti Dual modulation of inward rectifier potassium currents in olfactory neuronal cells by promiscuous G protein coupling of the oxytocin receptor J Neurochem 114 2010 1424 1435
32. A.J. Guastella, P.B. Mitchell, and M.R. Dadds Oxytocin increases gaze to the eye region of human faces Biol Psychiatry 63 2008 3 5 (Pubitemid 350234895)
33. K. Hanif, H.J. Goren, M.D. Hollenberg, and K. Lederis Oxytocin action: mechanisms for insulin like activity in isolated rat adipocytes Mol Pharmacol 22 1982 381 388 (Pubitemid 12028836)
34. K. Hanif, K. Lederis, M.D. Hollenberg, and H.J. Goren Inability of oxytocin to activate pyruvate dehydrogenase in the Brattleboro rat Science 216 1982 1010 1012 (Pubitemid 12025046)
35. T.R. Insel, L. Young, and Z. Wang Central oxytocin and reproductive behaviours Rev Reprod 2 1997 28 37 (Pubitemid 27165964)
36. M. Jankowski, D. Wang, F. Hajjar, S. Mukaddam-Daher, S.M. McCann, and J. Gutkowska Oxytocin and its receptors are synthesized in the rat vasculature Proc Natl Acad Sci USA 97 2000 207 211
37. A.V. Kalueff, and P. Tuohimaa The grooming analysis algorithm discriminates between different levels of anxiety in rats: potential utility for neurobehavioural stress research J Neurosci Methods 143 2005 169 177 (Pubitemid 40462262)
38. B.M. King, J.T. Cook, K.N. Rossiter, and B.L. Rollins Obesity-inducing amygdale lesions: examination of anterograde degeneration and retrograde transport Am J Physiol Regul Integr Comp Physiol 284 2003 R965 R982
39. A. Kiss, and J.D. Mikkelsen Oxytocin - anatomy and functional assignments: a minireview Endocr Regul 39 2005 97 105 (Pubitemid 44788388)
40. M. Kosfeld, M. Heinrichs, P.J. Zak, U. Fischbacher, and E. Fehr Oxytocin increases trust in humans Nature 435 2005 673 676 (Pubitemid 40825511)
41. R. Landgraf, T.J. Malkinson, W.L. Veale, K. Lederis, and Q.J. Pittman Vasopressin and oxytocin in rat brain in response to prostaglandin fever Am J Physiol Regulatory Integrative Comp Physiol 259 1990 R1056 R1062
42. E.A. Lawson, L.M. Holsen, M. Santin, E. Meenaghan, K.T. Eddy, and A.E. Becker Oxytocin secretion is associated with severity of disordered eating psychopathology and insular cortex hypoactivation in anorexia nervosa J Clin Endocrinol Metab 97 2012 E1898 E1908
43. J.M. Lipton, and J.R. Glyn Central administration of peptides alters thermoregulation in the rabbit Peptides 1 1980 15 18 (Pubitemid 11228973)
44. Y. Maejima, Y. Iwasaki, Y. Yamahara, M. Kodaira, U. Sedbazar, and T. Yada Peripheral oxytocin treatment ameliorates obesity by reducing food intake and visceral fat mass Aging (Albany, NY) 3 2011 1169 1177
45. S.S. Marroni, F.N. Nakano, C.D.C. Gati, J.A.C. Oliveira, J. Antunes-Rodriges, and N. Garcia-Cairasco Neuroanatomical and cellular substrates of hypergrooming induced by microinjection of oxytocin in central nucleus of amygdale, an experimental model of compulsive behavior Mol Psychiatry 12 2007 1103 1117 (Pubitemid 350191360)
46. G.A. Mason, J.D. Caldwell, D.A. Stanley, O.L. Hatley, A.J. Prange, and C.A. Pedersen Interactive effects of intracisternal oxytocin and other centrally active substances on colonic temperatures of mice Regul Pept 14 1986 253 260 (Pubitemid 16079709)
47. W.B. Mens, A. Witter, and T.B. Van Wismersma Graidanus Penetration of neurophyseal hormones from plasma into cerebrospinal fluid (CSF): half-times of disappearance of these neuropeptides from CSF Brain Res 262 1983 143 149 (Pubitemid 13188658)
48. J.L. Michaud, T. Rosenquist, N.R. May, and C.M. Fan Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1 Genes Dev 12 1998 3264 3275 (Pubitemid 28496270)
49. J.A. Miedlar, L. Rinaman, R.R. Vollmer, and J.A. Amico Oxytocin gene deletion mice overconsume palatable sucrose solution but not palatable lipid emulsions Am J Physiol Regul Integr Comp Physiol 293 3 2007 R1063 R1068
50. G.J. Morton, B.S. Thatcher, R.D. Reidelberger, K. Ogimoto, T. Wolden-Hanson, and D.G. Baskin Peripheral oxytocin suppresses food intake and causes weight loss in diet-induced obese rats Am J Physiol Endocrinol Metab 302 2012 E134 E144
51. K. Nagashima, S. Nakai, M. Tanaka, and K. Kanosue Neuronal circuitries involved in thermoregulation Auton Neurosci 85 2000 18 25
52. A.M. Naylor, W.D. Ruwe, and W.L. Veale Antipyretic action of centrally administered arginine vasopressin but not oxytocin in the cat Brain res 385 1986 156 160 (Pubitemid 16002160)
53. B.J. Oldfield, M.E. Giles, A. Watson, C. Anderson, L.M. Colvill, and M.J. McKinley The neurochemical characterisation of hypothalamic pathways projecting polysynaptically to brown adipose tissue in the rat Neuroscience 110 2002 515 526 (Pubitemid 34242779)
54. P.K. Olszewski, A. Klockars, A.M. Olszewska, R. Fredriksson, H.B. Schiöth, and A.S. Levine Molecular, immunohistochemical, and pharmacological evidence of oxytocin's role as inhibitor of carbohydrate but not fat intake Endocrinology 151 2010 4736 4744
55. J. Ott, and J.C. Scott The galactogogue action of the thymus and corpus luteum Proc Soc Exp Biol 8 1910 49
56. D.A. Poulain, and J.B. Wakerley Electrophysiology of hypothalamic magnocellular neurones secreting oxytocin and vasopressin Neuroscience 7 1982 773 808 (Pubitemid 12122237)
57. Rezai-Zadeh K, Münzberg H. Integration of sensorial information via central thermoregulatory leptin targets. Physiol Behav, http://dx.doi.org/10. 1016/j.physbeh.2013.02.014, in press.
58. L. Rinaman Oxytocinergic inputs to the nucleus of the solitary tract and dorsal motor nucleus of the vagus in neonatal rats J Comp Neurol 399 1998 101 109 (Pubitemid 28391557)
59. B.L. Rollins, and B.M. King Amygdala-lesion obesity: what is the role of the various amygdaloid nuclei? Am J Physiol Regul Integr Comp Physiol 279 2000 R1348 R1356
60. A.A. Romanovsky Thermoregulation: some concepts have changed. Functional architecture of the thermoregulatory system Am J Physiol Regul Integr Comp Physiol 292 2007 R37 R46
61. C.B. Rosa, J.F. Goularte, N.A. Trindade, A.P. De Oliveira, and A.A. Rasia-Filho Glutamate microinjected in the posterodorsal medial amygdala induces subtle increase in the consumption of a three-choice macronutrient self-selection diet in male rats Anat Rec (Hoboken) 294 2011 1226 1232
62. H.E. Ross, and L.J. Young Oxytocin and the neural mechanisms regulating social cognition and affiliative behavior Front Neuroendocrinol 30 2009 534 547
63. P.E. Sawchenko Evidence for differential regulation of corticotropin releasing factor and vasopressin immunoreactivities in parvocellular neurosecretory and autonomic-related projections of the paraventricular nucleus Brain Res 437 1987 253 263 (Pubitemid 18016213)
64. P.E. Sawchenko, and L.W. Swanson Immunohistochemical identification of neurons in the paraventricular nucleus of the hypothalamus that project to the medulla or to the spinal cord in the rat J Comp Neurol 205 1982 260 272 (Pubitemid 12135370)
65. A. Sclafani, L. Rinaman, R.R. Vollmer, and J.A. Amico Oxytocin knockout mice demonstrate enhanced intake of sweet and nonsweet carbohydrate solutions Am J Physiol Regul Integr Comp Physiol 292 2007 R1828 R1833
66. H. Shi, and T.J. Bartness Catecholaminergic enzymes, vasopressin and oxytocin distribution in Siberian hamster brain Brain Res Bull 53 2000 833 843 (Pubitemid 32120291)
67. S. Stanley, S. Pinto, J. Segal, C.A. Pérez, A. Viale, and J. DeFalco Identification of neuronal subpopulations that project from hypothalamus to both liver and adipose tissue polysynaptically Proc Natl Acad Sci U S A 107 2010 7024 7029
68. R. Stoop Neuromodulation by oxytocin and vasopressin Neuron 76 2012 142 159
69. D.F. Swaab, J.S. Purba, and M.A. Hofman Alterations in the hypothalamic paraventricular nucleus and its oxytocin neurons (putative satiety cells) in Prader-Willi syndrome: a study of five cases J Clin Endocrinol Metab 80 1995 573 579
70. A. Szeto, D.A. Nation, A.J. Mendez, J. Dominguez-Bendala, L.G. Brooks, and N. Schneiderman Oxytocin attenuates NADPH-dependent superoxide activity and IL-6 secretion in macrophages and vascular cells Am J Physiol Endocrinol Metab 295 2008 E1495 E1501
71. Y. Takayanagy, Y. Kasahara, T. Onaka, N. Takahashi, T. Kawada, and K. Nishimori Oxytocin receptor-deficient mice developed late-onset obesity Neuroreport 19 2008 951 955
72. J.G. Verbalis, M.J. McCann, C.M. McHale, and E.M. Stricker Oxytocin secretion in response to cholecystokinin and food: differentiation of nausea from satiety Science 232 1986 1417 1419 (Pubitemid 16059395)
73. V. Wiegand, and G. Gimpl Specification of the cholesterol interaction with the oxytocin receptor using a chimeric receptor approach Eur J Pharmacol 676 2012 12 19
74. D. Xi, N. Gandhi, M. Lai, and B.M. Kublaoui Ablation of Sim1 neurons causes obesity through hyperphagia and reduced energy expenditure PLoS ONE 7 2012 e36453
75. G. Zhang, H. Bai, H. Zhang, C. Dean, Q. Wu, and J. Li Neuropeptide exocytosis involving synaptotagmin-4 and oxytocin in hypothalamic programming of body weight and energy balance Neuron 69 2011 523 525
76. G. Zhang, and D. Cai Circadian intervention of obesity development via resting-stage feeding manipulation or oxytocin treatment Am J Physiol Endocrinol Metab 301 2011 E1004 E1012