Oxytocin during the initial stages of romantic attachment: Relations to couples' interactive reciprocity

Psychoneuroendocrinology

Volumn 37, Issue 8, 2012, Pages 1277-1285

  Schneiderman, Inna ^a   Zagoory Sharon, Orna ^a   Leckman, James F ^b   Feldman, Ruth ^a,b  

^a BAR ILAN UNIVERSITY   (Israel)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Oxytocin; Pair bonding; Reciprocity; Romantic attachment

Indexed keywords

OXYTOCIN;

ADULT; AFFECT; ANXIETY; ARTICLE; BEHAVIOR; CHILD PARENT RELATION; CONTROLLED STUDY; DISTRESS SYNDROME; EMOTIONAL STRESS; FEMALE; GENDER; HEALTH STATUS; HUMAN; HUMAN RELATION; INTERACTIVE RECIPROCITY; INTERVIEW; INTIMACY; LOVERS; MALE; MISCELLANEOUS NAMED GROUPS; OXYTOCIN BLOOD LEVEL; PHYSICAL DISTRESS; PRIORITY JOURNAL; REGRESSION ANALYSIS; ROMANTIC ATTACHMENT; SINGLE MAN; SINGLE WOMAN; STRESS; THINKING; TOUCH; WELLBEING;

ADOLESCENT; ADULT; BEHAVIOR; COURTSHIP; EMOTIONS; FAMILY CHARACTERISTICS; FEMALE; HUMANS; INTERPERSONAL RELATIONS; LOVE; MALE; OBJECT ATTACHMENT; OXYTOCIN; YOUNG ADULT;

EID: 84858701871     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2011.12.021     Document Type: Article

References (68)

1. Acevedo B.P., Aron A., Fisher H.E., Brown L.L. Neural correlates of long-term intense romantic love. Soc. Cogn. Affect Neurosci. 2011.
2. Aron A., Fisher H., Mashek D.J., Strong G., Li H., Brown L.L. Reward, motivation, and emotion systems associated with early-stage intense romantic love. J. Neurophysiol. 2005, 94:327-337.
3. Atzil S., Hendler T., Feldman R. Specifying the neurobiological basis of human attachment: brain, hormones, and behavior in synchronous and intrusive mothers. Neuropsychopharmacology 2011, 36:2603-2615.
4. Bartels A., Zeki S. The neural basis of romantic love. Neuroreport 2000, 11:3829-3834.
5. Bartels A., Zeki S. The neural correlates of maternal and romantic love. Neuroimage 2004, 21:1155-1166.
6. Bloom B.L., Asher S.J., White S.W. Marital disruption as a stressor: a review and analysis. Psychol. Bull. 1978, 85:867-894.
7. Brennan K.A., Clark C.L., Shaver P.R. Self-report measurement of adult attachment: An integrative overview. Attachment theory and close relationships 1998, 46-76. Guilford Press, New York. J.A. Simpson, W.S. Rholes (Eds.).
8. Burman B., Margolin G. Analysis of the association between marital relationships and health problems: an interactional perspective. Psychol. Bull. 1992, 112:39-63.
9. Burri A., Heinrichs M., Schedlowski M., Kruger T.H. The acute effects of intranasal oxytocin administration on endocrine and sexual function in males. Psychoneuroendocrinology 2008, 33:591-600.
10. Canetto S.S., Lester D. Love and achievement motives in women's and men's suicide notes. J. Psychol. 2002, 136:573-576.
11. Carmichael M.S., Humbert R., Dixen J., Palmisano G., Greenleaf W., Davidson J.M. Plasma oxytocin increases in the human sexual response. J. Clin. Endocrinol. Metab. 1987, 64:27-31.
12. Carmichael M.S., Warburton V.L., Dixen J., Davidson J.M. Relationships among cardiovascular, muscular, and oxytocin responses during human sexual activity. Arch. Sex. Behav. 1994, 23:59-79.
13. Carter C.S. Neuroendocrine perspectives on social attachment and love. Psychoneuroendocrinology 1998, 23:779-818.
14. Carter C.S., Pournajafi-Nazarloo H., Kramer K.M., Ziegler T.E., White-Traut R., Bello D., Schwertz D. Oxytocin: behavioral associations and potential as a salivary biomarker. Ann. N.Y. Acad. Sci. 2007, 1098:312-322.
15. Champagne F., Diorio J., Sharma S., Meaney M.J. Naturally occurring variations in maternal behavior in the rat are associated with differences in estrogen-inducible central oxytocin receptors. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:12736-12741.
16. Cho M.M., DeVries A.C., Williams J.R., Carter C.S. The effects of oxytocin and vasopressin on partner preferences in male and female prairie voles (Microtus ochrogaster). Behav. Neurosci. 1999, 113:1071-1079.
17. Ditzen B., Schaer M., Gabriel B., Bodenmann G., Ehlert U., Heinrichs M. Intranasal oxytocin increases positive communication and reduces cortisol levels during couple conflict. Biol. Psychiatry 2009, 65:728-731.
18. Donaldson Z.R., Spiegel L., Young L.J. Central vasopressin V1a receptor activation is independently necessary for both partner preference formation and expression in socially monogamous male prairie voles. Behav. Neurosci. 2010, 124:159-163.
19. Emanuele E. Of love and death: the emerging role of romantic disruption in suicidal behavior. Suicide Life Threat. Behav. 2009, 39:240.
20. Emanuele E., Bertona M., Minoretti P., Geroldi D. An open-label trial of l-5-hydroxytryptophan in subjects with romantic stress. Neuro Endocrinol. Lett. 2010, 31:663-666.
21. Emanuele E., Politi P., Bianchi M., Minoretti P., Bertona M., Geroldi D. Raised plasma nerve growth factor levels associated with early-stage romantic love. Psychoneuroendocrinology 2006, 31:288-294.
22. Feldman, R., 1998. Coding interactive behavior manual. Unpublished manual.
23. Feldman R. The relational basis of adolescent adjustment: trajectories of mother-child interactive behaviors from infancy to adolescence shape adolescents' adaptation. Attach. Hum. Dev. 2010, 12:173-192.
24. Feldman, R. Parent-infant synchrony: a bio-behavioral model of mutual influences in the formation of affiliative bonds. Monogr. Soc. Res. Child Dev., in press.
25. Feldman R., Eidelman A.I. Maternal postpartum behavior and the emergence of infant-mother and infant-father synchrony in preterm and full-term infants: the role of neonatal vagal tone. Dev. Psychobiol. 2007, 49:290-302.
26. Feldman R., Eidelman A.I. Triplets across the first 5 years: the discordant infant at birth remains at developmental risk. Pediatrics 2009, 124:316-323.
27. Feldman R., Gordon I., Schneiderman I., Weisman O., Zagoory-Sharon O. Natural variations in maternal and paternal care are associated with systematic changes in oxytocin following parent-infant contact. Psychoneuroendocrinology 2010, 35:1133-1141.
28. Feldman R., Gordon I., Zagoory-Sharon O. Maternal and paternal plasma, salivary, and urinary oxytocin and parent-infant synchrony: considering stress and affiliation components of human bonding. Dev. Sci. 2011, 14:752-761.
29. Feldman R., Klein P.S. Toddlers' self-regulated compliance to mothers, caregivers, and fathers: implications for theories of socialization. Dev. Psychol. 2003, 39:680-692.
30. Feldman R., Masalha S. Parent-child and triadic antecedents of children's social competence: cultural specificity, shared process. Dev. Psychol. 2010, 46:455-467.
31. Feldman R., Masalha S., Nadam R. Cultural perspective on work and family: dual-earner Israeli-Jewish and Arab families at the transition to parenthood. J. Fam. Psychol. 2001, 15:492-509.
32. Feldman, R., Schneiderman, 2006. Romantic Couples Interview. Unpublished Manual. Bar-Ilan University, Ramat-Gan, Israe.
33. Feldman R., Weller A., Leckman J.F., Kuint J., Eidelman A.I. The nature of the mother's tie to her infant: maternal bonding under conditions of proximity, separation, and potential loss. J. Child Psychol. Psychiatry 1999, 40:929-939.
34. Feldman R., Weller A., Sirota L., Eidelman A.I. Testing a family intervention hypothesis: the contribution of mother-infant skin-to-skin contact (kangaroo care) to family interaction, proximity, and touch. J. Fam. Psychol. 2003, 17:94-107.
35. Feldman R., Weller A., Zagoory-Sharon O., Levine A. Evidence for a neuroendocrinological foundation of human affiliation: plasma oxytocin levels across pregnancy and the postpartum period predict mother-infant bonding. Psychol. Sci. 2007, 18:965-970.
36. Feldman, R., Zagoory-Sharon, O., Maoz, R., Weisman, O., Gordon, I., Schneiderman, I., Shalev, I., Ebstein, R.P. Sensitive parenting is associated with plasma oxytocin and polymorphisms in the oxytocin receptor (OXTR) and CD38 genes. Biol. Psychiatry, in press, doi:10.1016/j.biopsych.2011.12.025.
37. Forsling M.L., Montgomery H., Halpin D., Windle R.J., Treacher D.F. Daily patterns of secretion of neurohypophysial hormones in man: effect of age. Exp. Physiol. 1998, 83:409-418.
38. Gonzaga G.C., Turner R.A., Keltner D., Campos B., Altemus M. Romantic love and sexual desire in close relationships. Emotion 2006, 6:163-179.
39. Gordon I., Martin C., Feldman R., Leckman J.F. Oxytocin and social motivation. Dev. Cogn. Neurosci. 2011, 1:471-493.
40. Gordon I., Zagoory-Sharon O., Leckman J.F., Feldman R. Oxytocin and the development of parenting in humans. Biol. Psychiatry 2010, 68:377-382.
41. Gordon I., Zagoory-Sharon O., Leckman J.F., Feldman R. Oxytocin, cortisol, and triadic family interactions. Physiol. Behav. 2010, 101:679-684.
42. Gordon I., Zagoory-Sharon O., Schneiderman I., Leckman J.F., Weller A., Feldman R. Oxytocin and cortisol in romantically unattached young adults: associations with bonding and psychological distress. Psychophysiology 2008, 45:349-352.
43. Grewen K.M., Girdler S.S., Amico J., Light K.C. Effects of partner support on resting oxytocin, cortisol, norepinephrine, and blood pressure before and after warm partner contact. Psychosom. Med. 2005, 67:531-538.
44. Guastella A.J., Mitchell P.B., Dadds M.R. Oxytocin increases gaze to the eye region of human faces. Biol. Psychiatry 2008, 63:3-5.
45. Holt-Lunstad J., Birmingham W.A., Light K.C. Influence of a "warm touch" support enhancement intervention among married couples on ambulatory blood pressure, oxytocin, alpha amylase, and cortisol. Psychosom. Med. 2008, 70:976-985.
46. Hurlemann R., Patin A., Onur O.A., Cohen M.X., Baumgartner T., Metzler S., Dziobek I., Gallinat J., Wagner M., Maier W., Kendrick K.M. Oxytocin enhances amygdala-dependent, socially reinforced learning and emotional empathy in humans. J. Neurosci. 2010, 30:4999-5007.
47. Insel T.R., Hulihan T.J. A gender-specific mechanism for pair bonding: oxytocin and partner preference formation in monogamous voles. Behav. Neurosci. 1995, 109:782-789.
48. Insel T.R., Young L., Wang Z. Molecular aspects of monogamy. Ann. N.Y. Acad. Sci. 1997, 807:302-316.
49. Jin D., Liu H.X., Hirai H., Torashima T., Nagai T., Lopatina O., Shnayder N.A., Yamada K., Noda M., Seike T., Fujita K., Takasawa S., Yokoyama S., Koizumi K., Shiraishi Y., Tanaka S., Hashii M., Yoshihara T., Higashida K., Islam M.S., Yamada N., Hayashi K., Noguchi N., Kato I., Okamoto H., Matsushima A., Salmina A., Munesue T., Shimizu N., Mochida S., Asano M., Higashida H. CD38 is critical for social behaviour by regulating oxytocin secretion. Nature 2007, 446:41-45.
50. Kim W., Kim S., Jeong J., Lee K.U., Ahn K.J., Chung Y.A., Hong K.Y., Chae J.H. Temporal changes in functional magnetic resonance imaging activation of heterosexual couples for visual stimuli of loved partners. Psychiatry Invest. 2009, 6:19-25.
51. Kirsch P., Esslinger C., Chen Q., Mier D., Lis S., Siddhanti S., Gruppe H., Mattay V.S., Gallhofer B., Meyer-Lindenberg A. Oxytocin modulates neural circuitry for social cognition and fear in humans. J. Neurosci. 2005, 25:11489-11493.
52. Kosfeld M., Heinrichs M., Zak P.J., Fischbacher U., Fehr E. Oxytocin increases trust in humans. Nature 2005, 435:673-676.
53. Leckman J.F., Mayes L.C., Feldman R., Evans D.W., King R.A., Cohen D.J. Early parental preoccupations and behaviors and their possible relationship to the symptoms of obsessive-compulsive disorder. Acta Psychiatr. Scand. Suppl. 1999, 396:1-26.
54. Levine A., Zagoory-Sharon O., Feldman R., Weller A. Oxytocin during pregnancy and early postpartum: individual patterns and maternal-fetal attachment. Peptides 2007, 28:1162-1169.
55. Marazziti D., Akiskal H.S., Rossi A., Cassano G.B. Alteration of the platelet serotonin transporter in romantic love. Psychol. Med. 1999, 29:741-745.
56. Marazziti D., Canale D. Hormonal changes when falling in love. Psychoneuroendocrinology 2004, 29:931-936.
57. Marazziti D., Dell'Osso B., Baroni S., Mungai F., Catena M., Rucci P., Albanese F., Giannaccini G., Betti L., Fabbrini L., Italiani P., Del Debbio A., Lucacchini A., Dell'Osso L. A relationship between oxytocin and anxiety of romantic attachment. Clin. Pract. Epidemiol. Ment. Health 2006, 2:28.
58. Marazziti D., Roncaglia I., Del Debbio A., Bianchi C., Massimetti G., Origlia N., Domenici L., Piccinni A., Dell'Osso L. Brain-derived neurotrophic factor in romantic attachment. Psychol. Med. 2009, 39:1927-1930.
59. Matsunaga M., Sato S., Isowa T., Tsuboi H., Konagaya T., Kaneko H., Ohira H. Profiling of serum proteins influenced by warm partner contact in healthy couples. Neuro Endocrinol. Lett. 2009, 30:227-236.
60. Ross H.E., Young L.J. Oxytocin and the neural mechanisms regulating social cognition and affiliative behavior. Front. Neuroendocrinol. 2009, 30:534-547.
61. Simon R.W., Marcussen K. Marital transitions, marital beliefs, and mental health. J. Health Soc. Behav. 1999, 40:111-125.
62. Tabak B.A., McCullough M.E., Szeto A., Mendez A.J., McCabe P.M. Oxytocin indexes relational distress following interpersonal harms in women. Psychoneuroendocrinology 2010, 36:115-122.
63. Taylor S.E., Saphire-Bernstein S., Seeman T.E. Are plasma oxytocin in women and plasma vasopressin in men biomarkers of distressed pair-bond relationships?. Psychol. Sci. 2010, 21:3-7.
64. van Anders S.M., Goldey K.L., Kuo P.X. The steroid/peptide theory of social bonds: integrating testosterone and peptide responses for classifying social behavioral contexts. Psychoneuroendocrinology 2011, 36:1265-1275.
65. Weisman O., Feldman R., Goldstein A. Parental and romantic attachment shape brain processing of infant cues. Biol. Psychol. 2011.
66. White-Traut R., Watanabe K., Pournajafi-Nazarloo H., Schwertz D., Bell A., Carter C.S. Detection of salivary oxytocin levels in lactating women. Dev. Psychobiol. 2009, 51:367-373.
67. Williams J.R., Insel T.R., Harbaugh C.R., Carter C.S. Oxytocin administered centrally facilitates formation of a partner preference in female prairie voles (Microtus ochrogaster). J. Neuroendocrinol. 1994, 6:247-250.
68. Wotjak C.T., Ganster J., Kohl G., Holsboer F., Landgraf R., Engelmann M. Dissociated central and peripheral release of vasopressin, but not oxytocin, in response to repeated swim stress: new insights into the secretory capacities of peptidergic neurons. Neuroscience 1998, 85:1209-1222.