-
1
-
-
56049107038
-
PGC-1 coactivators and skeletal muscle adaptations in health and disease
-
Arany Z. PGC-1 coactivators and skeletal muscle adaptations in health and disease. Curr. Opin. Genet. Dev. 2008, 18:426-434.
-
(2008)
Curr. Opin. Genet. Dev.
, vol.18
, pp. 426-434
-
-
Arany, Z.1
-
2
-
-
33745627066
-
Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha
-
Arany Z., Novikov M., Chin S., Ma Y., Rosenzweig A., Spiegelman B.M. Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha. Proc. Natl. Acad. Sci. USA 2006, 103:10086-10091.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 10086-10091
-
-
Arany, Z.1
Novikov, M.2
Chin, S.3
Ma, Y.4
Rosenzweig, A.5
Spiegelman, B.M.6
-
3
-
-
0842264056
-
Evidence of a novel quantitative-trait locus for obesity on chromosome 4p in Mexican Americans
-
Arya R., Duggirala R., Jenkinson C.P., Almasy L., Blangero J., O'Connell P., Stern M.P. Evidence of a novel quantitative-trait locus for obesity on chromosome 4p in Mexican Americans. Am. J. Hum. Genet. 2004, 74:272-282.
-
(2004)
Am. J. Hum. Genet.
, vol.74
, pp. 272-282
-
-
Arya, R.1
Duggirala, R.2
Jenkinson, C.P.3
Almasy, L.4
Blangero, J.5
O'Connell, P.6
Stern, M.P.7
-
4
-
-
0036903174
-
Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1
-
Baar K., Wende A.R., Jones T.E., Marison M., Nolte L.A., Chen M., Kelly D.P., Holloszy J.O. Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. FASEB J. 2002, 16:1879-1886.
-
(2002)
FASEB J.
, vol.16
, pp. 1879-1886
-
-
Baar, K.1
Wende, A.R.2
Jones, T.E.3
Marison, M.4
Nolte, L.A.5
Chen, M.6
Kelly, D.P.7
Holloszy, J.O.8
-
5
-
-
34548847172
-
Diabetic larvae and obese flies-emerging studies of metabolism in Drosophila
-
Baker K.D., Thummel C.S. Diabetic larvae and obese flies-emerging studies of metabolism in Drosophila. Cell Metab. 2007, 6:257-266.
-
(2007)
Cell Metab.
, vol.6
, pp. 257-266
-
-
Baker, K.D.1
Thummel, C.S.2
-
6
-
-
7644239149
-
Drosophila, an emerging model for cardiac disease
-
Bier E., Bodmer R. Drosophila, an emerging model for cardiac disease. Gene 2004, 342:1-11.
-
(2004)
Gene
, vol.342
, pp. 1-11
-
-
Bier, E.1
Bodmer, R.2
-
7
-
-
78049425280
-
High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila
-
Birse R.T., Choi J., Reardon K., Rodriguez J., Graham S., Diop S., Ocorr K., Bodmer R., Oldham S. High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila. Cell Metab. 2010, 12:533-544.
-
(2010)
Cell Metab.
, vol.12
, pp. 533-544
-
-
Birse, R.T.1
Choi, J.2
Reardon, K.3
Rodriguez, J.4
Graham, S.5
Diop, S.6
Ocorr, K.7
Bodmer, R.8
Oldham, S.9
-
10
-
-
20044393471
-
Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands
-
Broughton S.J., Piper M.D., Ikeya T., Bass T.M., Jacobson J., Driege Y., Martinez P., Hafen E., Withers D.J., Leevers S.J., Partridge L. Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands. Proc. Natl. Acad. Sci. USA 2005, 102:3105-3110.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 3105-3110
-
-
Broughton, S.J.1
Piper, M.D.2
Ikeya, T.3
Bass, T.M.4
Jacobson, J.5
Driege, Y.6
Martinez, P.7
Hafen, E.8
Withers, D.J.9
Leevers, S.J.10
Partridge, L.11
-
11
-
-
0042315364
-
Cardiac lipid accumulation associated with diastolic dysfunction in obese mice
-
Christoffersen C., Bollano E., Lindegaard M.L., Bartels E.D., Goetze J.P., Andersen C.B., Nielsen L.B. Cardiac lipid accumulation associated with diastolic dysfunction in obese mice. Endocrinology 2003, 144:3483-3490.
-
(2003)
Endocrinology
, vol.144
, pp. 3483-3490
-
-
Christoffersen, C.1
Bollano, E.2
Lindegaard, M.L.3
Bartels, E.D.4
Goetze, J.P.5
Andersen, C.B.6
Nielsen, L.B.7
-
12
-
-
84860350761
-
Drosophila as a model to study the genetic mechanisms of obesity-associated heart dysfunction
-
Diop S.B., Bodmer R. Drosophila as a model to study the genetic mechanisms of obesity-associated heart dysfunction. J.Cell. Mol. Med. 2012, 16:966-971.
-
(2012)
J.Cell. Mol. Med.
, vol.16
, pp. 966-971
-
-
Diop, S.B.1
Bodmer, R.2
-
13
-
-
0037012907
-
Regulation of SREBP processing and membrane lipid production by phospholipids in Drosophila
-
Dobrosotskaya I.Y., Seegmiller A.C., Brown M.S., Goldstein J.L., Rawson R.B. Regulation of SREBP processing and membrane lipid production by phospholipids in Drosophila. Science 2002, 296:879-883.
-
(2002)
Science
, vol.296
, pp. 879-883
-
-
Dobrosotskaya, I.Y.1
Seegmiller, A.C.2
Brown, M.S.3
Goldstein, J.L.4
Rawson, R.B.5
-
14
-
-
33644660537
-
PGC-1 coactivators: inducible regulators of energy metabolism in health and disease
-
Finck B.N., Kelly D.P. PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J.Clin. Invest. 2006, 116:615-622.
-
(2006)
J.Clin. Invest.
, vol.116
, pp. 615-622
-
-
Finck, B.N.1
Kelly, D.P.2
-
15
-
-
34248589911
-
Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) regulatory cascade in cardiac physiology and disease
-
Finck B.N., Kelly D.P. Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) regulatory cascade in cardiac physiology and disease. Circulation 2007, 115:2540-2548.
-
(2007)
Circulation
, vol.115
, pp. 2540-2548
-
-
Finck, B.N.1
Kelly, D.P.2
-
16
-
-
64949151149
-
A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts
-
Fink M., Callol-Massot C., Chu A., Ruiz-Lozano P., Izpisua Belmonte J.C., Giles W., Bodmer R., Ocorr K. A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts. Biotechniques 2009, 46:101-113.
-
(2009)
Biotechniques
, vol.46
, pp. 101-113
-
-
Fink, M.1
Callol-Massot, C.2
Chu, A.3
Ruiz-Lozano, P.4
Izpisua Belmonte, J.C.5
Giles, W.6
Bodmer, R.7
Ocorr, K.8
-
17
-
-
81155123695
-
PGC-1-related coactivator (PRC), a sensor of metabolic stress, orchestrates a redox-sensitive program of inflammatory gene expression
-
Gleyzer N., Scarpulla R.C. PGC-1-related coactivator (PRC), a sensor of metabolic stress, orchestrates a redox-sensitive program of inflammatory gene expression. J.Biol. Chem. 2011, 286:39715-39725.
-
(2011)
J.Biol. Chem.
, vol.286
, pp. 39715-39725
-
-
Gleyzer, N.1
Scarpulla, R.C.2
-
18
-
-
0034596268
-
CDNA Cloning and mRNA analysis of PGC-1 in epitrochlearis muscle in swimming-exercised rats
-
Goto M., Terada S., Kato M., Katoh M., Yokozeki T., Tabata I., Shimokawa T. cDNA Cloning and mRNA analysis of PGC-1 in epitrochlearis muscle in swimming-exercised rats. Biochem. Biophys. Res. Commun. 2000, 274:350-354.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.274
, pp. 350-354
-
-
Goto, M.1
Terada, S.2
Kato, M.3
Katoh, M.4
Yokozeki, T.5
Tabata, I.6
Shimokawa, T.7
-
19
-
-
26944489689
-
Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila
-
Grönke S., Mildner A., Fellert S., Tennagels N., Petry S., Müller G., Jäckle H., Kühnlein R.P. Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila. Cell Metab. 2005, 1:323-330.
-
(2005)
Cell Metab.
, vol.1
, pp. 323-330
-
-
Grönke, S.1
Mildner, A.2
Fellert, S.3
Tennagels, N.4
Petry, S.5
Müller, G.6
Jäckle, H.7
Kühnlein, R.P.8
-
20
-
-
84860340270
-
A cardiac microRNA governs systemic energy homeostasis by regulation of MED13
-
Grueter C.E., van Rooij E., Johnson B.A., DeLeon S.M., Sutherland L.B., Qi X., Gautron L., Elmquist J.K., Bassel-Duby R., Olson E.N. A cardiac microRNA governs systemic energy homeostasis by regulation of MED13. Cell 2012, 149:671-683.
-
(2012)
Cell
, vol.149
, pp. 671-683
-
-
Grueter, C.E.1
van Rooij, E.2
Johnson, B.A.3
DeLeon, S.M.4
Sutherland, L.B.5
Qi, X.6
Gautron, L.7
Elmquist, J.K.8
Bassel-Duby, R.9
Olson, E.N.10
-
21
-
-
80052454265
-
ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1
-
Haemmerle G., Moustafa T., Woelkart G., Büttner S., Schmidt A., van de Weijer T., Hesselink M., Jaeger D., Kienesberger P.C., Zierler K., et al. ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1. Nat. Med. 2011, 17:1076-1085.
-
(2011)
Nat. Med.
, vol.17
, pp. 1076-1085
-
-
Haemmerle, G.1
Moustafa, T.2
Woelkart, G.3
Büttner, S.4
Schmidt, A.5
van de Weijer, T.6
Hesselink, M.7
Jaeger, D.8
Kienesberger, P.C.9
Zierler, K.10
-
22
-
-
84860454425
-
Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c
-
Hagiwara A., Cornu M., Cybulski N., Polak P., Betz C., Trapani F., Terracciano L., Heim M.H., Rüegg M.A., Hall M.N. Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c. Cell Metab. 2012, 15:725-738.
-
(2012)
Cell Metab.
, vol.15
, pp. 725-738
-
-
Hagiwara, A.1
Cornu, M.2
Cybulski, N.3
Polak, P.4
Betz, C.5
Trapani, F.6
Terracciano, L.7
Heim, M.H.8
Rüegg, M.A.9
Hall, M.N.10
-
23
-
-
14644425217
-
Mitochondrial energy metabolism in heart failure: a question of balance
-
Huss J.M., Kelly D.P. Mitochondrial energy metabolism in heart failure: a question of balance. J.Clin. Invest. 2005, 115:547-555.
-
(2005)
J.Clin. Invest.
, vol.115
, pp. 547-555
-
-
Huss, J.M.1
Kelly, D.P.2
-
24
-
-
79952216996
-
Biology of obesity: lessons from animal models of obesity
-
Kanasaki K., Koya D. Biology of obesity: lessons from animal models of obesity. J.Biomed. Biotechnol. 2011, 2011:197636.
-
(2011)
J.Biomed. Biotechnol.
, vol.2011
, pp. 197636
-
-
Kanasaki, K.1
Koya, D.2
-
25
-
-
84863808286
-
Thematic review series: Lipid droplet synthesis and metabolism: from yeast to man. Lipid droplet-based storage fat metabolism in Drosophila
-
Kühnlein R.P. Thematic review series: Lipid droplet synthesis and metabolism: from yeast to man. Lipid droplet-based storage fat metabolism in Drosophila. J.Lipid Res. 2012, 53:1430-1436.
-
(2012)
J.Lipid Res.
, vol.53
, pp. 1430-1436
-
-
Kühnlein, R.P.1
-
26
-
-
33744544947
-
Fatty acid auxotrophy in Drosophila larvae lacking SREBP
-
Kunte A.S., Matthews K.A., Rawson R.B. Fatty acid auxotrophy in Drosophila larvae lacking SREBP. Cell Metab. 2006, 3:439-448.
-
(2006)
Cell Metab.
, vol.3
, pp. 439-448
-
-
Kunte, A.S.1
Matthews, K.A.2
Rawson, R.B.3
-
27
-
-
47549114849
-
Transcriptional coactivators PGC-1alpha and PGC-1beta control overlapping programs required for perinatal maturation of the heart
-
Lai L., Leone T.C., Zechner C., Schaeffer P.J., Kelly S.M., Flanagan D.P., Medeiros D.M., Kovacs A., Kelly D.P. Transcriptional coactivators PGC-1alpha and PGC-1beta control overlapping programs required for perinatal maturation of the heart. Genes Dev. 2008, 22:1948-1961.
-
(2008)
Genes Dev.
, vol.22
, pp. 1948-1961
-
-
Lai, L.1
Leone, T.C.2
Zechner, C.3
Schaeffer, P.J.4
Kelly, S.M.5
Flanagan, D.P.6
Medeiros, D.M.7
Kovacs, A.8
Kelly, D.P.9
-
28
-
-
77955734995
-
Sestrins at the crossroad between stress and aging
-
Lee J.H., Bodmer R., Bier E., Karin M. Sestrins at the crossroad between stress and aging. Aging (Albany, N.Y. Online) 2010, 2:369-374.
-
(2010)
Aging (Albany, N.Y. Online)
, vol.2
, pp. 369-374
-
-
Lee, J.H.1
Bodmer, R.2
Bier, E.3
Karin, M.4
-
29
-
-
0036118922
-
Transcriptional activation of energy metabolic switches in the developing and hypertrophied heart
-
Lehman J.J., Kelly D.P. Transcriptional activation of energy metabolic switches in the developing and hypertrophied heart. Clin. Exp. Pharmacol. Physiol. 2002, 29:339-345.
-
(2002)
Clin. Exp. Pharmacol. Physiol.
, vol.29
, pp. 339-345
-
-
Lehman, J.J.1
Kelly, D.P.2
-
30
-
-
46849094545
-
Role of the PGC-1 family in the metabolic adaptation of goldfish to diet and temperature
-
LeMoine C.M., Genge C.E., Moyes C.D. Role of the PGC-1 family in the metabolic adaptation of goldfish to diet and temperature. J.Exp. Biol. 2008, 211:1448-1455.
-
(2008)
J.Exp. Biol.
, vol.211
, pp. 1448-1455
-
-
LeMoine, C.M.1
Genge, C.E.2
Moyes, C.D.3
-
31
-
-
78651490662
-
Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila
-
Lim H.Y., Wang W., Wessells R.J., Ocorr K., Bodmer R. Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila. Genes Dev. 2011, 25:189-200.
-
(2011)
Genes Dev.
, vol.25
, pp. 189-200
-
-
Lim, H.Y.1
Wang, W.2
Wessells, R.J.3
Ocorr, K.4
Bodmer, R.5
-
32
-
-
0037127204
-
Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor
-
Lin J., Puigserver P., Donovan J., Tarr P., Spiegelman B.M. Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor. J.Biol. Chem. 2002, 277:1645-1648.
-
(2002)
J.Biol. Chem.
, vol.277
, pp. 1645-1648
-
-
Lin, J.1
Puigserver, P.2
Donovan, J.3
Tarr, P.4
Spiegelman, B.M.5
-
33
-
-
84870686652
-
DJun and Vri/dNFIL3 are major regulators of cardiac aging in Drosophila
-
Monnier V., Iché-Torres M., Rera M., Contremoulins V., Guichard C., Lalevée N., Tricoire H., Perrin L. dJun and Vri/dNFIL3 are major regulators of cardiac aging in Drosophila. PLoS Genet. 2012, 8:e1003081.
-
(2012)
PLoS Genet.
, vol.8
, pp. e1003081
-
-
Monnier, V.1
Iché-Torres, M.2
Rera, M.3
Contremoulins, V.4
Guichard, C.5
Lalevée, N.6
Tricoire, H.7
Perrin, L.8
-
34
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha V.K., Lindgren C.M., Eriksson K.F., Subramanian A., Sihag S., Lehar J., Puigserver P., Carlsson E., Ridderstråle M., Laurila E., et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat. Genet. 2003, 34:267-273.
-
(2003)
Nat. Genet.
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
Subramanian, A.4
Sihag, S.5
Lehar, J.6
Puigserver, P.7
Carlsson, E.8
Ridderstråle, M.9
Laurila, E.10
-
35
-
-
84884970596
-
Spargel/dPGC-1 is a new downstream effector in the insulin-TOR signaling pathway in Drosophila
-
Mukherjee S., Duttaroy A. Spargel/dPGC-1 is a new downstream effector in the insulin-TOR signaling pathway in Drosophila. Genetics 2013, 195:433-441.
-
(2013)
Genetics
, vol.195
, pp. 433-441
-
-
Mukherjee, S.1
Duttaroy, A.2
-
36
-
-
0037340930
-
A Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians
-
Muller Y.L., Bogardus C., Pedersen O., Baier L. A Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians. Diabetes 2003, 52:895-898.
-
(2003)
Diabetes
, vol.52
, pp. 895-898
-
-
Muller, Y.L.1
Bogardus, C.2
Pedersen, O.3
Baier, L.4
-
37
-
-
84873486964
-
A Drosophila model of high sugar diet-induced cardiomyopathy
-
Na J., Musselman L.P., Pendse J., Baranski T.J., Bodmer R., Ocorr K., Cagan R. A Drosophila model of high sugar diet-induced cardiomyopathy. PLoS Genet. 2013, 9:e1003175.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003175
-
-
Na, J.1
Musselman, L.P.2
Pendse, J.3
Baranski, T.J.4
Bodmer, R.5
Ocorr, K.6
Cagan, R.7
-
38
-
-
0028906170
-
Identification and expression of the Drosophila adipokinetic hormone gene
-
Noyes B.E., Katz F.N., Schaffer M.H. Identification and expression of the Drosophila adipokinetic hormone gene. Mol. Cell. Endocrinol. 1995, 109:133-141.
-
(1995)
Mol. Cell. Endocrinol.
, vol.109
, pp. 133-141
-
-
Noyes, B.E.1
Katz, F.N.2
Schaffer, M.H.3
-
39
-
-
34247257761
-
KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging
-
Ocorr K., Reeves N.L., Wessells R.J., Fink M., Chen H.S., Akasaka T., Yasuda S., Metzger J.M., Giles W., Posakony J.W., Bodmer R. KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging. Proc. Natl. Acad. Sci. USA 2007, 104:3943-3948.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 3943-3948
-
-
Ocorr, K.1
Reeves, N.L.2
Wessells, R.J.3
Fink, M.4
Chen, H.S.5
Akasaka, T.6
Yasuda, S.7
Metzger, J.M.8
Giles, W.9
Posakony, J.W.10
Bodmer, R.11
-
40
-
-
80055117330
-
Semi-automated optical heartbeat analysis of small hearts
-
Ocorr K., Fink M., Cammarato A., Bernstein S., Bodmer R. Semi-automated optical heartbeat analysis of small hearts. J.Vis. Exp. 2009, 31:1435.
-
(2009)
J.Vis. Exp.
, vol.31
, pp. 1435
-
-
Ocorr, K.1
Fink, M.2
Cammarato, A.3
Bernstein, S.4
Bodmer, R.5
-
41
-
-
84901823728
-
Methods to assess Drosophila heart development, function and aging
-
Ocorr K., Vogler G., Bodmer R. Methods to assess Drosophila heart development, function and aging. Methods 2014, 68:265-272.
-
(2014)
Methods
, vol.68
, pp. 265-272
-
-
Ocorr, K.1
Vogler, G.2
Bodmer, R.3
-
42
-
-
72749086098
-
Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been
-
Osborne T.F., Espenshade P.J. Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been. Genes Dev. 2009, 23:2578-2591.
-
(2009)
Genes Dev.
, vol.23
, pp. 2578-2591
-
-
Osborne, T.F.1
Espenshade, P.J.2
-
43
-
-
0035940416
-
A conditional tissue-specific transgene expression system using inducible GAL4
-
Osterwalder T., Yoon K.S., White B.H., Keshishian H. A conditional tissue-specific transgene expression system using inducible GAL4. Proc. Natl. Acad. Sci. USA 2001, 98:12596-12601.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12596-12601
-
-
Osterwalder, T.1
Yoon, K.S.2
White, B.H.3
Keshishian, H.4
-
44
-
-
84856470679
-
PGC-1 coactivators in the cardiovascular system
-
Patten I.S., Arany Z. PGC-1 coactivators in the cardiovascular system. Trends Endocrinol. Metab. 2012, 23:90-97.
-
(2012)
Trends Endocrinol. Metab.
, vol.23
, pp. 90-97
-
-
Patten, I.S.1
Arany, Z.2
-
45
-
-
0037477855
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
-
Patti M.E., Butte A.J., Crunkhorn S., Cusi K., Berria R., Kashyap S., Miyazaki Y., Kohane I., Costello M., Saccone R., et al. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1. Proc. Natl. Acad. Sci. USA 2003, 100:8466-8471.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8466-8471
-
-
Patti, M.E.1
Butte, A.J.2
Crunkhorn, S.3
Cusi, K.4
Berria, R.5
Kashyap, S.6
Miyazaki, Y.7
Kohane, I.8
Costello, M.9
Saccone, R.10
-
46
-
-
50049116472
-
SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth
-
Porstmann T., Santos C.R., Griffiths B., Cully M., Wu M., Leevers S., Griffiths J.R., Chung Y.L., Schulze A. SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth. Cell Metab. 2008, 8:224-236.
-
(2008)
Cell Metab.
, vol.8
, pp. 224-236
-
-
Porstmann, T.1
Santos, C.R.2
Griffiths, B.3
Cully, M.4
Wu, M.5
Leevers, S.6
Griffiths, J.R.7
Chung, Y.L.8
Schulze, A.9
-
47
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver P., Wu Z., Park C.W., Graves R., Wright M., Spiegelman B.M. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 1998, 92:829-839.
-
(1998)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
48
-
-
33750682655
-
The human gene map for performance and health-related fitness phenotypes: the 2005 update
-
Rankinen T., Bray M.S., Hagberg J.M., Pérusse L., Roth S.M., Wolfarth B., Bouchard C. The human gene map for performance and health-related fitness phenotypes: the 2005 update. Med. Sci. Sports Exerc. 2006, 38:1863-1888.
-
(2006)
Med. Sci. Sports Exerc.
, vol.38
, pp. 1863-1888
-
-
Rankinen, T.1
Bray, M.S.2
Hagberg, J.M.3
Pérusse, L.4
Roth, S.M.5
Wolfarth, B.6
Bouchard, C.7
-
49
-
-
80455143200
-
Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog
-
Rera M., Bahadorani S., Cho J., Koehler C.L., Ulgherait M., Hur J.H., Ansari W.S., Lo T., Jones D.L., Walker D.W. Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog. Cell Metab. 2011, 14:623-634.
-
(2011)
Cell Metab.
, vol.14
, pp. 623-634
-
-
Rera, M.1
Bahadorani, S.2
Cho, J.3
Koehler, C.L.4
Ulgherait, M.5
Hur, J.H.6
Ansari, W.S.7
Lo, T.8
Jones, D.L.9
Walker, D.W.10
-
50
-
-
0035940413
-
P[Switch], a system for spatial and temporal control of gene expression in Drosophila melanogaster
-
Roman G., Endo K., Zong L., Davis R.L. P[Switch], a system for spatial and temporal control of gene expression in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 2001, 98:12602-12607.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12602-12607
-
-
Roman, G.1
Endo, K.2
Zong, L.3
Davis, R.L.4
-
51
-
-
77958021516
-
PGC-1 coactivators in cardiac development and disease
-
Rowe G.C., Jiang A., Arany Z. PGC-1 coactivators in cardiac development and disease. Circ. Res. 2010, 107:825-838.
-
(2010)
Circ. Res.
, vol.107
, pp. 825-838
-
-
Rowe, G.C.1
Jiang, A.2
Arany, Z.3
-
52
-
-
12144286554
-
Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner
-
Russell L.K., Mansfield C.M., Lehman J.J., Kovacs A., Courtois M., Saffitz J.E., Medeiros D.M., Valencik M.L., McDonald J.A., Kelly D.P. Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner. Circ. Res. 2004, 94:525-533.
-
(2004)
Circ. Res.
, vol.94
, pp. 525-533
-
-
Russell, L.K.1
Mansfield, C.M.2
Lehman, J.J.3
Kovacs, A.4
Courtois, M.5
Saffitz, J.E.6
Medeiros, D.M.7
Valencik, M.L.8
McDonald, J.A.9
Kelly, D.P.10
-
53
-
-
79957960940
-
Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network
-
Scarpulla R.C. Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network. Biochim. Biophys. Acta 2011, 1813:1269-1278.
-
(2011)
Biochim. Biophys. Acta
, vol.1813
, pp. 1269-1278
-
-
Scarpulla, R.C.1
-
54
-
-
80052812434
-
The PGC-1 cascade as a therapeutic target for heart failure
-
Schilling J., Kelly D.P. The PGC-1 cascade as a therapeutic target for heart failure. J.Mol. Cell. Cardiol. 2011, 51:578-583.
-
(2011)
J.Mol. Cell. Cardiol.
, vol.51
, pp. 578-583
-
-
Schilling, J.1
Kelly, D.P.2
-
55
-
-
0036480346
-
The SREBP pathway in Drosophila: regulation by palmitate, not sterols
-
Seegmiller A.C., Dobrosotskaya I., Goldstein J.L., Ho Y.K., Brown M.S., Rawson R.B. The SREBP pathway in Drosophila: regulation by palmitate, not sterols. Dev. Cell 2002, 2:229-238.
-
(2002)
Dev. Cell
, vol.2
, pp. 229-238
-
-
Seegmiller, A.C.1
Dobrosotskaya, I.2
Goldstein, J.L.3
Ho, Y.K.4
Brown, M.S.5
Rawson, R.B.6
-
56
-
-
75649131899
-
The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signalling
-
Tiefenböck S.K., Baltzer C., Egli N.A., Frei C. The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signalling. EMBO J. 2010, 29:171-183.
-
(2010)
EMBO J.
, vol.29
, pp. 171-183
-
-
Tiefenböck, S.K.1
Baltzer, C.2
Egli, N.A.3
Frei, C.4
-
57
-
-
84856879434
-
The Drosophila PGC-1α homolog spargel modulates the physiological effects of endurance exercise
-
Tinkerhess M.J., Healy L., Morgan M., Sujkowski A., Matthys E., Zheng L., Wessells R.J. The Drosophila PGC-1α homolog spargel modulates the physiological effects of endurance exercise. PLoS ONE 2012, 7:e31633.
-
(2012)
PLoS ONE
, vol.7
, pp. e31633
-
-
Tinkerhess, M.J.1
Healy, L.2
Morgan, M.3
Sujkowski, A.4
Matthys, E.5
Zheng, L.6
Wessells, R.J.7
-
58
-
-
0033977890
-
The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes
-
Vega R.B., Huss J.M., Kelly D.P. The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes. Mol. Cell. Biol. 2000, 20:1868-1876.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1868-1876
-
-
Vega, R.B.1
Huss, J.M.2
Kelly, D.P.3
-
59
-
-
80055115988
-
Visualizing the beating heart in Drosophila
-
Vogler G., Ocorr K. Visualizing the beating heart in Drosophila. J.Vis. Exp. 2009, 31:1425.
-
(2009)
J.Vis. Exp.
, vol.31
, pp. 1425
-
-
Vogler, G.1
Ocorr, K.2
-
60
-
-
9644278037
-
Insulin regulation of heart function in aging fruit flies
-
Wessells R.J., Fitzgerald E., Cypser J.R., Tatar M., Bodmer R. Insulin regulation of heart function in aging fruit flies. Nat. Genet. 2004, 36:1275-1281.
-
(2004)
Nat. Genet.
, vol.36
, pp. 1275-1281
-
-
Wessells, R.J.1
Fitzgerald, E.2
Cypser, J.R.3
Tatar, M.4
Bodmer, R.5
-
61
-
-
31944438501
-
Drosophila as a model for the identification of genes causing adult human heart disease
-
Wolf M.J., Amrein H., Izatt J.A., Choma M.A., Reedy M.C., Rockman H.A. Drosophila as a model for the identification of genes causing adult human heart disease. Proc. Natl. Acad. Sci. USA 2006, 103:1394-1399.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 1394-1399
-
-
Wolf, M.J.1
Amrein, H.2
Izatt, J.A.3
Choma, M.A.4
Reedy, M.C.5
Rockman, H.A.6
-
62
-
-
34547670846
-
Genetic epidemiology of obesity
-
Yang W., Kelly T., He J. Genetic epidemiology of obesity. Epidemiol. Rev. 2007, 29:49-61.
-
(2007)
Epidemiol. Rev.
, vol.29
, pp. 49-61
-
-
Yang, W.1
Kelly, T.2
He, J.3
-
63
-
-
0033763206
-
How obesity develops: insights from the new biology
-
York D., Bouchard C. How obesity develops: insights from the new biology. Endocrine 2000, 13:143-154.
-
(2000)
Endocrine
, vol.13
, pp. 143-154
-
-
York, D.1
Bouchard, C.2
-
64
-
-
78649508058
-
Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity
-
Zechner C., Lai L., Zechner J.F., Geng T., Yan Z., Rumsey J.W., Collia D., Chen Z., Wozniak D.F., Leone T.C., Kelly D.P. Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity. Cell Metab. 2010, 12:633-642.
-
(2010)
Cell Metab.
, vol.12
, pp. 633-642
-
-
Zechner, C.1
Lai, L.2
Zechner, J.F.3
Geng, T.4
Yan, Z.5
Rumsey, J.W.6
Collia, D.7
Chen, Z.8
Wozniak, D.F.9
Leone, T.C.10
Kelly, D.P.11
-
65
-
-
79551495757
-
Role of cardiac steatosis and lipotoxicity in obesity cardiomyopathy
-
Zhang Y., Ren J. Role of cardiac steatosis and lipotoxicity in obesity cardiomyopathy. Hypertension 2011, 57:148-150.
-
(2011)
Hypertension
, vol.57
, pp. 148-150
-
-
Zhang, Y.1
Ren, J.2
-
66
-
-
0034652225
-
Lipotoxic heart disease in obese rats: implications for human obesity
-
Zhou Y.T., Grayburn P., Karim A., Shimabukuro M., Higa M., Baetens D., Orci L., Unger R.H. Lipotoxic heart disease in obese rats: implications for human obesity. Proc. Natl. Acad. Sci. USA 2000, 97:1784-1789.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 1784-1789
-
-
Zhou, Y.T.1
Grayburn, P.2
Karim, A.3
Shimabukuro, M.4
Higa, M.5
Baetens, D.6
Orci, L.7
Unger, R.H.8
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