-
1
-
-
2342496712
-
FoxOs at the crossroads of cellular metabolism, differentiation, and transformation
-
Accili, D., and K. C. Arden, 2004 FoxOs at the crossroads of cellular metabolism, differentiation, and transformation. Cell 117: 421-426.
-
(2004)
Cell
, vol.117
, pp. 421-426
-
-
Accili, D.1
Arden, K.C.2
-
2
-
-
0036741749
-
Altering Drosophila S6 kinase activity is consistent with a role for S6 kinase in growth
-
Barcelo, H., and M. J. Stewart, 2002 Altering Drosophila S6 kinase activity is consistent with a role for S6 kinase in growth. Genesis 34: 83-85.
-
(2002)
Genesis
, vol.34
, pp. 83-85
-
-
Barcelo, H.1
Stewart, M.J.2
-
3
-
-
80155126156
-
PGC1alpha promotes tumor growth by inducing gene expression programs supporting lipogenesis
-
Bhalla, K., B. J. Hwang, R. E. Dewi, L. Ou, W. Twaddel et al., 2011 PGC1alpha promotes tumor growth by inducing gene expression programs supporting lipogenesis. Cancer Res. 71: 6888-6898.
-
(2011)
Cancer Res.
, vol.71
, pp. 6888-6898
-
-
Bhalla, K.1
Hwang, B.J.2
Dewi, R.E.3
Ou, L.4
Twaddel, W.5
-
4
-
-
3242877807
-
ESLpred: SVM-based method for subcellular localization of eukaryotic proteins using dipeptide composition and PSI-BLAST
-
Bhasin, M., and G. P. Raghava, 2004 ESLpred: SVM-based method for subcellular localization of eukaryotic proteins using dipeptide composition and PSI-BLAST. Nucleic Acids Res. 32: W414-W419.
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Bhasin, M.1
Raghava, G.P.2
-
5
-
-
10644276290
-
Drosophila, the golden bug, emerges as a tool for human genetics
-
Bier, E., 2005 Drosophila, the golden bug, emerges as a tool for human genetics. Nat. Rev. Genet. 6: 9-23.
-
(2005)
Nat. Rev. Genet.
, vol.6
, pp. 9-23
-
-
Bier, E.1
-
6
-
-
34249846686
-
NucPred-predicting nuclear localization of proteins
-
Brameier, M., A. Krings, and R. M. Maccallum, 2007 NucPred-predicting nuclear localization of proteins. Bioinformatics 23: 1159-1160.
-
(2007)
Bioinformatics
, vol.23
, pp. 1159-1160
-
-
Brameier, M.1
Krings, A.2
McCallum, R.M.3
-
7
-
-
70450200706
-
Clueless, a conserved Drosophila gene required for mitochondrial subcellular localization, interacts genetically with parkin
-
Cox, R. T., and A. C. Spradling, 2009 Clueless, a conserved Drosophila gene required for mitochondrial subcellular localization, interacts genetically with parkin. Dis. Model. Mech. 2: 490-499.
-
(2009)
Dis. Model. Mech.
, vol.2
, pp. 490-499
-
-
Cox, R.T.1
Spradling, A.C.2
-
8
-
-
36749081539
-
mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex
-
Cunningham, J. T., J. T. Rodgers, D. H. Arlow, F. Vazquez, V. K. Mootha et al., 2007 mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex. Nature 450: 736-740.
-
(2007)
Nature
, vol.450
, pp. 736-740
-
-
Cunningham, J.T.1
Rodgers, J.T.2
Arlow, D.H.3
Vazquez, F.4
Mootha, V.K.5
-
9
-
-
84856450023
-
Is the history of a surgical discectomy related to the source of chronic low back pain?
-
DePalma, M. J., J. M. Ketchum, T. R. Saullo, and B. L. Laplante, 2012 Is the history of a surgical discectomy related to the source of chronic low back pain? Pain Physician 15: E53-E58.
-
(2012)
Pain Physician
, vol.15
-
-
DePalma, M.J.1
Ketchum, J.M.2
Saullo, T.R.3
Laplante, B.L.4
-
10
-
-
0026599345
-
The 35-kDa mammalian splicing factor SC35 mediates specific interactions between U1 and U2 small nuclear ribonucleoprotein particles at the 39 splice site
-
Fu, X. D., and T. Maniatis, 1992 The 35-kDa mammalian splicing factor SC35 mediates specific interactions between U1 and U2 small nuclear ribonucleoprotein particles at the 39 splice site. Proc. Natl. Acad. Sci. USA 89: 1725-1729.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 1725-1729
-
-
Fu, X.D.1
Maniatis, T.2
-
11
-
-
84871984916
-
Homozygous mutation of the Insulin-like Growth Factor-I Receptor gene (IGF1R) in a patient with severe pre-and postnatal growth failure, and congenital malformations
-
Gannage-Yared, M. H., J. Klammt, E. Chouery, S. Corbani, H. Megarbane et al., 2012 Homozygous mutation of the Insulin-like Growth Factor-I Receptor gene (IGF1R) in a patient with severe pre-and postnatal growth failure, and congenital malformations. Eur. J. Endocrinol 168: K1-K7.
-
(2012)
Eur. J. Endocrinol
, vol.168
-
-
Gannage-Yared, M.H.1
Klammt, J.2
Chouery, E.3
Corbani, S.4
Megarbane, H.5
-
12
-
-
34248207609
-
High-resolution dynamics of the transcriptional response to nutrition in Drosophila: A key role for dFOXO
-
Gershman, B., O. Puig, L. Hang, R. M. Peitzsch, M. Tatar et al., 2007 High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO. Physiol. Genomics 29: 24-34.
-
(2007)
Physiol. Genomics
, vol.29
, pp. 24-34
-
-
Gershman, B.1
Puig, O.2
Hang, L.3
Peitzsch, R.M.4
Tatar, M.5
-
13
-
-
27844497945
-
FOXO transcription factors at the interface between longevity and tumor suppression
-
Greer, E. L., and A. Brunet, 2005 FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 24: 7410-7425.
-
(2005)
Oncogene
, vol.24
, pp. 7410-7425
-
-
Greer, E.L.1
Brunet, A.2
-
14
-
-
59649094753
-
Insulin/TOR signaling in growth and homeostasis: A view from the fly world
-
Grewal, S. S., 2009 Insulin/TOR signaling in growth and homeostasis: a view from the fly world. Int. J. Biochem. Cell Biol. 41: 1006-1010.
-
(2009)
Int. J. Biochem. Cell Biol.
, vol.41
, pp. 1006-1010
-
-
Grewal, S.S.1
-
15
-
-
0036742659
-
Inhibition of cellular growth and proliferation by dTOR overexpression in Drosophila
-
Hennig, K. M., and T. P. Neufeld, 2002 Inhibition of cellular growth and proliferation by dTOR overexpression in Drosophila. Genesis 34: 107-110.
-
(2002)
Genesis
, vol.34
, pp. 107-110
-
-
Hennig, K.M.1
Neufeld, T.P.2
-
16
-
-
33745235142
-
TOR coordinates bulk and targeted endocytosis in the Drosophila melanogaster fat body to regulate cell growth
-
Hennig, K. M., J. Colombani, and T. P. Neufeld, 2006 TOR coordinates bulk and targeted endocytosis in the Drosophila melanogaster fat body to regulate cell growth. J. Cell Biol. 173: 963-974.
-
(2006)
J. Cell Biol.
, vol.173
, pp. 963-974
-
-
Hennig, K.M.1
Colombani, J.2
Neufeld, T.P.3
-
17
-
-
73349138892
-
Regulation of tissue growth through nutrient sensing
-
Hietakangas, V., and S. M. Cohen, 2009 Regulation of tissue growth through nutrient sensing. Annu. Rev. Genet. 43: 389-410.
-
(2009)
Annu. Rev. Genet.
, vol.43
, pp. 389-410
-
-
Hietakangas, V.1
Cohen, S.M.2
-
18
-
-
0242539698
-
The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling
-
Junger, M. A., F. Rintelen, H. Stocker, J. D. Wasserman, M. Vegh et al., 2003 The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. J. Biol. 2: 20.
-
(2003)
J. Biol.
, vol.2
, pp. 20
-
-
Junger, M.A.1
Rintelen, F.2
Stocker, H.3
Wasserman, J.D.4
Vegh, M.5
-
19
-
-
58649104919
-
Six classes of nuclear localization signals specific to different binding grooves of importin alpha
-
Kosugi, S., M. Hasebe, N. Matsumura, H. Takashima, E. Miyamoto-Sato et al., 2009 Six classes of nuclear localization signals specific to different binding grooves of importin alpha. J. Biol. Chem. 284: 478-485.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 478-485
-
-
Kosugi, S.1
Hasebe, M.2
Matsumura, N.3
Takashima, H.4
Miyamoto-Sato, E.5
-
20
-
-
84859778293
-
mTOR signaling in growth control and disease
-
Laplante, M., and D. M. Sabatini, 2012 mTOR signaling in growth control and disease. Cell 149: 274-293.
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
21
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
Lin, J., C. Handschin, and B. M. Spiegelman, 2005 Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab. 1: 361-370.
-
(2005)
Cell Metab.
, vol.1
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
22
-
-
79959635928
-
Separation of the gluconeogenic and mitochondrial functions of PGC-1{alpha} through S6 kinase
-
Lustig, Y., J. L. Ruas, J. L. Estall, J. C. Lo, S. Devarakonda et al., 2011 Separation of the gluconeogenic and mitochondrial functions of PGC-1{alpha} through S6 kinase. Genes Dev. 25: 1232-1244.
-
(2011)
Genes Dev.
, vol.25
, pp. 1232-1244
-
-
Lustig, Y.1
Ruas, J.L.2
Estall, J.L.3
Lo, J.C.4
Devarakonda, S.5
-
23
-
-
0344629443
-
Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster
-
Miron, M., P. Lasko, and N. Sonenberg, 2003 Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster. Mol. Cell. Biol. 23: 9117-9126.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 9117-9126
-
-
Miron, M.1
Lasko, P.2
Sonenberg, N.3
-
24
-
-
0033638283
-
Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1
-
Monsalve, M., Z. Wu, G. Adelmant, P. Puigserver, M. Fan et al., 2000 Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Mol. Cell 6: 307-316.
-
(2000)
Mol. Cell
, vol.6
, pp. 307-316
-
-
Monsalve, M.1
Wu, Z.2
Adelmant, G.3
Puigserver, P.4
Fan, M.5
-
25
-
-
0032843917
-
Drosophila S6 kinase: A regulator of cell size
-
Montagne, J., M. J. Stewart, H. Stocker, E. Hafen, S. C. Kozma et al., 1999 Drosophila S6 kinase: a regulator of cell size. Science 285: 2126-2129.
-
(1999)
Science
, vol.285
, pp. 2126-2129
-
-
Montagne, J.1
Stewart, M.J.2
Stocker, H.3
Hafen, E.4
Kozma, S.C.5
-
26
-
-
3242721268
-
mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells
-
Murakami, M., T. Ichisaka, M. Maeda, N. Oshiro, K. Hara et al., 2004 mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells. Mol. Cell. Biol. 24: 6710-6718.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 6710-6718
-
-
Murakami, M.1
Ichisaka, T.2
Maeda, M.3
Oshiro, N.4
Hara, K.5
-
27
-
-
0035805162
-
Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size
-
Potter, C. J., H. Huang, and T. Xu, 2001 Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size. Cell 105: 357-368.
-
(2001)
Cell
, vol.105
, pp. 357-368
-
-
Potter, C.J.1
Huang, H.2
Xu, T.3
-
28
-
-
0042161896
-
Control of cell number by Drosophila FOXO: Downstream and feedback regulation of the insulin receptor pathway
-
Puig, O., M. T. Marr, M. L. Ruhf, and R. Tjian, 2003 Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway. Genes Dev. 17: 2006-2020.
-
(2003)
Genes Dev.
, vol.17
, pp. 2006-2020
-
-
Puig, O.1
Marr, M.T.2
Ruhf, M.L.3
Tjian, R.4
-
29
-
-
80455143200
-
Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog
-
Rera, M., S. Bahadorani, J. Cho, C. L. Koehler, M. Ulgherait et al., 2011 Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog. Cell Metab. 14: 623-634.
-
(2011)
Cell Metab.
, vol.14
, pp. 623-634
-
-
Rera, M.1
Bahadorani, S.2
Cho, J.3
Koehler, C.L.4
Ulgherait, M.5
-
30
-
-
0041620432
-
The PredictProtein server
-
Rost, B., and J. Liu, 2003 The PredictProtein server. Nucleic Acids Res. 31: 3300-3304.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3300-3304
-
-
Rost, B.1
Liu, J.2
-
31
-
-
33745150462
-
Ribosomal protein S6 phosphorylation: From protein synthesis to cell size
-
Ruvinsky, I., and O. Meyuhas, 2006 Ribosomal protein S6 phosphorylation: from protein synthesis to cell size. Trends Biochem. Sci. 31: 342-348.
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 342-348
-
-
Ruvinsky, I.1
Meyuhas, O.2
-
32
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel, A. R., and C. R. Kahn, 2001 Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414: 799-806.
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
33
-
-
33748752151
-
The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity
-
Schieke, S. M., D. Phillips, J. P. Mccoy, Jr., A. M. Aponte, R. F. Shen et al., 2006 The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity. J. Biol. Chem. 281: 27643-27652.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 27643-27652
-
-
Schieke, S.M.1
Phillips, D.2
McCoy Jr., J.P.3
Aponte, A.M.4
Shen, R.F.5
-
34
-
-
0038001567
-
Impaired oxidative phosphorylation in skeletal muscle of intrauterine growth-retarded rats
-
Selak, M. A., B. T. Storey, I. Peterside, and R. A. Simmons, 2003 Impaired oxidative phosphorylation in skeletal muscle of intrauterine growth-retarded rats. Am. J. Physiol. Endocrinol. Metab. 285: E130-E137.
-
(2003)
Am. J. Physiol. Endocrinol. Metab.
, vol.285
-
-
Selak, M.A.1
Storey, B.T.2
Peterside, I.3
Simmons, R.A.4
-
35
-
-
75649131899
-
The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signalling
-
Tiefenbock, S. K., C. Baltzer, N. A. Egli, and C. Frei, 2010 The Drosophila PGC-1 homologue Spargel coordinates mitochondrial activity to insulin signalling. EMBO J. 29: 171-183.
-
(2010)
EMBO J.
, vol.29
, pp. 171-183
-
-
Tiefenbock, S.K.1
Baltzer, C.2
Egli, N.A.3
Frei, C.4
-
36
-
-
84856879434
-
The Drosophila PGC-1alpha homolog spargel modulates the physiological effects of endurance exercise
-
Tinkerhess, M. J., L. Healy, M. Morgan, A. Sujkowski, E. Matthys et al., 2012 The Drosophila PGC-1alpha homolog spargel modulates the physiological effects of endurance exercise. PLoS ONE 7: e31633.
-
(2012)
PLoS ONE
, vol.7
-
-
Tinkerhess, M.J.1
Healy, L.2
Morgan, M.3
Sujkowski, A.4
Matthys, E.5
-
37
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger, S., R. Loewith, and M. N. Hall, 2006 TOR signaling in growth and metabolism. Cell 124: 471-484.
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
38
-
-
0034312315
-
Regulation of cellular growth by the Drosophila target of rapamycin dTOR
-
Zhang, H., J. P. Stallock, J. C. Ng, C. Reinhard, and T. P. Neufeld, 2000 Regulation of cellular growth by the Drosophila target of rapamycin dTOR. Genes Dev. 14: 2712-2724.
-
(2000)
Genes Dev.
, vol.14
, pp. 2712-2724
-
-
Zhang, H.1
Stallock, J.P.2
Ng, J.C.3
Reinhard, C.4
Neufeld, T.P.5
-
39
-
-
33644781670
-
Drosophila target of rapamycin kinase functions as a multimer
-
Zhang, Y., C. J. Billington, Jr., D. Pan, and T. P. Neufeld, 2006 Drosophila target of rapamycin kinase functions as a multimer. Genetics 172: 355-362.
-
(2006)
Genetics
, vol.172
, pp. 355-362
-
-
Zhang, Y.1
Billington Jr., C.J.2
Pan, D.3
Neufeld, T.P.4
|