메뉴 건너뛰기




Volumn 9, Issue 7, 2014, Pages

Uncoupling between inflammatory and fibrotic responses to silica: Evidence from MyD88 knockout mice

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; CRYOPYRIN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 18 RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 33; INTERLEUKIN 33 RECEPTOR; MYELOID DIFFERENTIATION FACTOR 88; PLATELET DERIVED GROWTH FACTOR B; PROTEIN ASC; SILICON DIOXIDE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 84904635167     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0099383     Document Type: Article
Times cited : (43)

References (70)
  • 3
    • 84867288891 scopus 로고    scopus 로고
    • Work-related lung diseases
    • Weston A (2011) Work-related lung diseases. IARC Sci Publ: 387-405.
    • (2011) IARC Sci Publ , pp. 387-405
    • Weston, A.1
  • 5
    • 33947123566 scopus 로고    scopus 로고
    • New developments in the understanding of immunology in silicosis
    • Huaux F (2007) New developments in the understanding of immunology in silicosis. Curr Opin Allergy Clin Immunol 7: 168-173.
    • (2007) Curr Opin Allergy Clin Immunol , vol.7 , pp. 168-173
    • Huaux, F.1
  • 6
    • 80053901859 scopus 로고    scopus 로고
    • Contrasting macrophage activation by fine and ultrafine titanium dioxide particles is associated with different uptake mechanisms
    • Scherbart AM, Langer J, Bushmelev A, van Berlo D, Haberzettl P, et al. (2011) Contrasting macrophage activation by fine and ultrafine titanium dioxide particles is associated with different uptake mechanisms. Part Fibre Toxicol 8: 31.
    • (2011) Part Fibre Toxicol , vol.8 , pp. 31
    • Scherbart, A.M.1    Langer, J.2    Bushmelev, A.3    Van Berlo, D.4    Haberzettl, P.5
  • 7
    • 64349101066 scopus 로고    scopus 로고
    • Critical role of MARCO in crystalline silica-induced pulmonary inflammation
    • Thakur SA, Beamer CA, Migliaccio CT, Holian A (2009) Critical role of MARCO in crystalline silica-induced pulmonary inflammation. Toxicol Sci 108: 462-471.
    • (2009) Toxicol Sci , vol.108 , pp. 462-471
    • Thakur, S.A.1    Beamer, C.A.2    Migliaccio, C.T.3    Holian, A.4
  • 9
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • DOI 10.1126/science.1156995
    • Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, et al. (2008) Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320: 674-677. (Pubitemid 351928351)
    • (2008) Science , vol.320 , Issue.5876 , pp. 674-677
    • Dostert, C.1    Petrilli, V.2    Van Bruggen, R.3    Steele, C.4    Mossman, B.T.5    Tschopp, J.6
  • 11
    • 47849097202 scopus 로고    scopus 로고
    • Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
    • Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, et al. (2008) Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 9: 847-856.
    • (2008) Nat Immunol , vol.9 , pp. 847-856
    • Hornung, V.1    Bauernfeind, F.2    Halle, A.3    Samstad, E.O.4    Kono, H.5
  • 12
    • 77957165679 scopus 로고    scopus 로고
    • Innate immune processes are sufficient for driving silicosis in mice
    • Beamer CA, Migliaccio CT, Jessop F, Trapkus M, Yuan D, et al. (2010) Innate immune processes are sufficient for driving silicosis in mice. J Leukoc Biol 88: 547-557.
    • (2010) J Leukoc Biol , vol.88 , pp. 547-557
    • Beamer, C.A.1    Migliaccio, C.T.2    Jessop, F.3    Trapkus, M.4    Yuan, D.5
  • 13
    • 0034967219 scopus 로고    scopus 로고
    • Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis
    • Kolb M, Margetts PJ, Anthony DC, Pitossi F, Gauldie J (2001) Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis. J Clin Invest 107: 1529-1536. (Pubitemid 32574639)
    • (2001) Journal of Clinical Investigation , vol.107 , Issue.12 , pp. 1529-1536
    • Kolb, M.1    Margetts, P.J.2    Anthony, D.C.3    Pitossi, F.4    Gauldie, J.5
  • 14
    • 0025211892 scopus 로고
    • Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis
    • Piguet PF, Collart MA, Grau GE, Sappino AP, Vassalli P (1990) Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis. Nature 344: 245-247.
    • (1990) Nature , vol.344 , pp. 245-247
    • Piguet, P.F.1    Collart, M.A.2    Grau, G.E.3    Sappino, A.P.4    Vassalli, P.5
  • 17
    • 84864013020 scopus 로고    scopus 로고
    • Innate immune activation by inhaled lipopolysaccharide, independent of oxidative stress, exacerbates silica-induced pulmonary fibrosis in mice
    • Brass DM, Spencer JC, Li Z, Potts-Kant E, Reilly SM, et al. (2012) Innate immune activation by inhaled lipopolysaccharide, independent of oxidative stress, exacerbates silica-induced pulmonary fibrosis in mice. PLoS One 7: e40789.
    • (2012) PLoS One , vol.7
    • Brass, D.M.1    Spencer, J.C.2    Li, Z.3    Potts-Kant, E.4    Reilly, S.M.5
  • 19
    • 84862809213 scopus 로고    scopus 로고
    • Association between proinflammatory responses of respirable silica dust and adverse health effects among dust-exposed workers
    • Zhou T, Rong Y, Liu Y, Zhou Y, Guo J, et al. (2012) Association between proinflammatory responses of respirable silica dust and adverse health effects among dust-exposed workers. J Occup Environ Med 54: 459-465.
    • (2012) J Occup Environ Med , vol.54 , pp. 459-465
    • Zhou, T.1    Rong, Y.2    Liu, Y.3    Zhou, Y.4    Guo, J.5
  • 20
    • 31944451558 scopus 로고    scopus 로고
    • Silica and the immune system
    • Pernis B (2005) Silica and the immune system. Acta Biomed 76 Suppl 2: 38-44.
    • (2005) Acta Biomed , vol.76 , Issue.SUPPL. 2 , pp. 38-44
    • Pernis, B.1
  • 21
    • 0036709969 scopus 로고    scopus 로고
    • A universal role for MyD88 in TLR/IL-1R-mediated signaling
    • DOI 10.1016/S0968-0004(02)02145-X, PII S096800040202145X
    • Janssens S, Beyaert R (2002) A universal role for MyD88 in TLR/IL-1R-mediated signaling. Trends Biochem Sci 27: 474-482. (Pubitemid 35246257)
    • (2002) Trends in Biochemical Sciences , vol.27 , Issue.9 , pp. 474-482
    • Janssens, S.1    Beyaert, R.2
  • 22
    • 0033166472 scopus 로고    scopus 로고
    • Unresponsiveness of MyD88-deficient mice to endotoxin
    • DOI 10.1016/S1074-7613(00)80086-2
    • Kawai T, Adachi O, Ogawa T, Takeda K, Akira S (1999) Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11: 115-122. (Pubitemid 29359962)
    • (1999) Immunity , vol.11 , Issue.1 , pp. 115-122
    • Kawai, T.1    Adachi, O.2    Ogawa, T.3    Takeda, K.4    Akira, S.5
  • 24
    • 0032482168 scopus 로고    scopus 로고
    • Production of mice deficient in genes for interleukin (IL)-1alpha, IL-1beta, IL-1alpha/beta, and IL-1 receptor antagonist shows that IL-1beta is crucial in turpentine-induced fever development and glucocorticoid secretion
    • DOI 10.1084/jem.187.9.1463
    • Horai R, Asano M, Sudo K, Kanuka H, Suzuki M, et al. (1998) Production of mice deficient in genes for interleukin (IL)-1alpha, IL-1beta, IL-1alpha/beta, and IL-1 receptor antagonist shows that IL-1beta is crucial in turpentine-induced fever development and glucocorticoid secretion. J Exp Med 187: 1463-1475. (Pubitemid 28215405)
    • (1998) Journal of Experimental Medicine , vol.187 , Issue.9 , pp. 1463-1475
    • Horai, R.1    Asano, M.2    Sudo, K.3    Kanuka, H.4    Suzuki, M.5    Nishihara, M.6    Takahashi, M.7    Iwakura, Y.8
  • 25
    • 11144273976 scopus 로고    scopus 로고
    • Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis
    • DOI 10.1038/nm1140
    • Wang T, Town T, Alexopoulou L, Anderson JF, Fikrig E, et al. (2004) Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nat Med 10: 1366-1373. (Pubitemid 40022719)
    • (2004) Nature Medicine , vol.10 , Issue.12 , pp. 1366-1373
    • Wang, T.1    Town, T.2    Alexopoulou, L.3    Anderson, J.F.4    Fikrig, E.5    Flavell, R.A.6
  • 29
    • 0000526378 scopus 로고
    • A Simple Method for the Silver Impregnation of Reticulum
    • Gordon H, Sweets HH (1936) A Simple Method for the Silver Impregnation of Reticulum. Am J Pathol 12: 545-552 541.
    • (1936) Am J Pathol , vol.12
    • Gordon, H.1    Sweets, H.H.2
  • 30
    • 84862068459 scopus 로고    scopus 로고
    • Genetic variation in Toll-like receptors and disease susceptibility
    • Netea MG, Wijmenga C, O'Neill LA (2012) Genetic variation in Toll-like receptors and disease susceptibility. Nat Immunol 13: 535-542.
    • (2012) Nat Immunol , vol.13 , pp. 535-542
    • Netea, M.G.1    Wijmenga, C.2    O'Neill, L.A.3
  • 31
    • 77953471537 scopus 로고    scopus 로고
    • IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis
    • Lo Re S, Dumoutier L, Couillin I, Van Vyve C, Yakoub Y, et al. (2010) IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis. J Immunol 184: 6367-6377.
    • (2010) J Immunol , vol.184 , pp. 6367-6377
    • Lo Re, S.1    Dumoutier, L.2    Couillin, I.3    Van Vyve, C.4    Yakoub, Y.5
  • 32
    • 84875664377 scopus 로고    scopus 로고
    • CD4+ T lymphocytes in lung fibrosis: Diverse subsets, diverse functions
    • Lo Re S, Lison D, Huaux F (2013) CD4+ T lymphocytes in lung fibrosis: diverse subsets, diverse functions. J Leukoc Biol 93: 499-510.
    • (2013) J Leukoc Biol , vol.93 , pp. 499-510
    • Lo Re, S.1    Lison, D.2    Huaux, F.3
  • 33
    • 82555197056 scopus 로고    scopus 로고
    • Platelet-derived growth factor-producing CD4+ Foxp3+ regulatory T lymphocytes promote lung fibrosis
    • Lo Re S, Lecocq M, Uwambayinema F, Yakoub Y, Delos M, et al. (2011) Platelet-derived growth factor-producing CD4+ Foxp3+ regulatory T lymphocytes promote lung fibrosis. Am J Respir Crit Care Med 184: 1270-1281.
    • (2011) Am J Respir Crit Care Med , vol.184 , pp. 1270-1281
    • Lo Re, S.1    Lecocq, M.2    Uwambayinema, F.3    Yakoub, Y.4    Delos, M.5
  • 36
    • 80053070208 scopus 로고    scopus 로고
    • Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-beta1-dependent and -independent mechanisms
    • Mi S, Li Z, Yang HZ, Liu H, Wang JP, et al. (2011) Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-beta1-dependent and -independent mechanisms. J Immunol 187: 3003-3014.
    • (2011) J Immunol , vol.187 , pp. 3003-3014
    • Mi, S.1    Li, Z.2    Yang, H.Z.3    Liu, H.4    Wang, J.P.5
  • 37
    • 84885949158 scopus 로고    scopus 로고
    • Neutralization of interleukin-1 beta attenuates silica-induced lung inflammation and fibrosis in C57BL/6 mice
    • Guo J, Gu N, Chen J, Shi T, Zhou Y, et al. (2013) Neutralization of interleukin-1 beta attenuates silica-induced lung inflammation and fibrosis in C57BL/6 mice. Arch Toxicol 87: 1963-1973.
    • (2013) Arch Toxicol , vol.87 , pp. 1963-1973
    • Guo, J.1    Gu, N.2    Chen, J.3    Shi, T.4    Zhou, Y.5
  • 38
    • 40449118020 scopus 로고    scopus 로고
    • Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent
    • Doz E, Noulin N, Boichot E, Guenon I, Fick L, et al. (2008) Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent. J Immunol 180: 1169-1178.
    • (2008) J Immunol , vol.180 , pp. 1169-1178
    • Doz, E.1    Noulin, N.2    Boichot, E.3    Guenon, I.4    Fick, L.5
  • 40
    • 84881012470 scopus 로고    scopus 로고
    • Myeloid differentiation factor 88-dependent signaling is critical for acute organic dust-induced airway inflammation in mice
    • Bauer C, Kielian T, Wyatt TA, Romberger DJ, West WW, et al. (2013) Myeloid differentiation factor 88-dependent signaling is critical for acute organic dust-induced airway inflammation in mice. Am J Respir Cell Mol Biol 48: 781-789.
    • (2013) Am J Respir Cell Mol Biol , vol.48 , pp. 781-789
    • Bauer, C.1    Kielian, T.2    Wyatt, T.A.3    Romberger, D.J.4    West, W.W.5
  • 41
    • 76249115506 scopus 로고    scopus 로고
    • IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema
    • Couillin I, Vasseur V, Charron S, Gasse P, Tavernier M, et al. (2009) IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema. J Immunol 183: 8195-8202.
    • (2009) J Immunol , vol.183 , pp. 8195-8202
    • Couillin, I.1    Vasseur, V.2    Charron, S.3    Gasse, P.4    Tavernier, M.5
  • 42
    • 77955076653 scopus 로고    scopus 로고
    • Type I interferon signaling contributes to chronic inflammation in a murine model of silicosis
    • Giordano G, van den Brule S, Lo Re S, Triqueneaux P, Uwambayinema F, et al. (2010) Type I interferon signaling contributes to chronic inflammation in a murine model of silicosis. Toxicol Sci 116: 682-692.
    • (2010) Toxicol Sci , vol.116 , pp. 682-692
    • Giordano, G.1    Van Den Brule, S.2    Lo Re, S.3    Triqueneaux, P.4    Uwambayinema, F.5
  • 45
    • 84862561821 scopus 로고    scopus 로고
    • Resistin-like molecule alpha1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis
    • Madala SK, Edukulla R, Davis KR, Schmidt S, Davidson C, et al. (2012) Resistin-like molecule alpha1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis. Respir Res 13: 51.
    • (2012) Respir Res , vol.13 , pp. 51
    • Madala, S.K.1    Edukulla, R.2    Davis, K.R.3    Schmidt, S.4    Davidson, C.5
  • 46
    • 80051721588 scopus 로고    scopus 로고
    • Fibrogenic and redox-related but not proinflammatory genes are upregulated in Lewis rat model of chronic silicosis
    • Langley RJ, Mishra NC, Pena-Philippides JC, Rice BJ, Seagrave JC, et al. (2011) Fibrogenic and redox-related but not proinflammatory genes are upregulated in Lewis rat model of chronic silicosis. J Toxicol Environ Health A 74: 1261-1279.
    • (2011) J Toxicol Environ Health A , vol.74 , pp. 1261-1279
    • Langley, R.J.1    Mishra, N.C.2    Pena-Philippides, J.C.3    Rice, B.J.4    Seagrave, J.C.5
  • 47
    • 27644554218 scopus 로고    scopus 로고
    • The role of pro- and anti-inflammatory responses in silica-induced lung fibrosis
    • Barbarin V, Nihoul A, Misson P, Arras M, Delos M, et al. (2005) The role of pro- and anti-inflammatory responses in silica-induced lung fibrosis. Respir Res 6: 112.
    • (2005) Respir Res , vol.6 , pp. 112
    • Barbarin, V.1    Nihoul, A.2    Misson, P.3    Arras, M.4    Delos, M.5
  • 49
    • 83455230751 scopus 로고    scopus 로고
    • TLR4 activity is required in the resolution of pulmonary inflammation and fibrosis after acute and chronic lung injury
    • Yang HZ, Wang JP, Mi S, Liu HZ, Cui B, et al. (2012) TLR4 activity is required in the resolution of pulmonary inflammation and fibrosis after acute and chronic lung injury. Am J Pathol 180: 275-292.
    • (2012) Am J Pathol , vol.180 , pp. 275-292
    • Yang, H.Z.1    Wang, J.P.2    Mi, S.3    Liu, H.Z.4    Cui, B.5
  • 50
    • 84859083851 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor (AhR) regulates silica-induced inflammation but not fibrosis
    • Beamer CA, Seaver BP, Shepherd DM (2012) Aryl hydrocarbon receptor (AhR) regulates silica-induced inflammation but not fibrosis. Toxicol Sci 126: 554-568.
    • (2012) Toxicol Sci , vol.126 , pp. 554-568
    • Beamer, C.A.1    Seaver, B.P.2    Shepherd, D.M.3
  • 51
    • 79955467443 scopus 로고    scopus 로고
    • Lung fibrosis induced by crystalline silica particles is uncoupled from lung inflammation in NMRI mice
    • Rabolli V, Lo Re S, Uwambayinema F, Yakoub Y, Lison D, et al. (2011) Lung fibrosis induced by crystalline silica particles is uncoupled from lung inflammation in NMRI mice. Toxicol Lett 203: 127-134.
    • (2011) Toxicol Lett , vol.203 , pp. 127-134
    • Rabolli, V.1    Lo Re, S.2    Uwambayinema, F.3    Yakoub, Y.4    Lison, D.5
  • 52
    • 84857495469 scopus 로고    scopus 로고
    • Pranlukast, a cysteinyl leukotriene type 1 receptor antagonist, attenuates the progression but not the onset of silica-induced pulmonary fibrosis in mice
    • Shimbori C, Shiota N, Okunishi H (2012) Pranlukast, a cysteinyl leukotriene type 1 receptor antagonist, attenuates the progression but not the onset of silica-induced pulmonary fibrosis in mice. Int Arch Allergy Immunol 158: 241-251.
    • (2012) Int Arch Allergy Immunol , vol.158 , pp. 241-251
    • Shimbori, C.1    Shiota, N.2    Okunishi, H.3
  • 53
    • 35449007633 scopus 로고    scopus 로고
    • Silicosis: A Review
    • DOI 10.1016/j.disamonth.2007.09.020, PII S0011502907001101, Silicosis: A Review
    • Greenberg MI, Waksman J, Curtis J (2007) Silicosis: a review. Dis Mon 53: 394-416. (Pubitemid 47633553)
    • (2007) Disease-a-Month , vol.53 , Issue.8 , pp. 394-416
    • Greenberg, M.I.1    Waksman, J.2    Curtis, J.3
  • 54
    • 0030800795 scopus 로고    scopus 로고
    • Adenovector-mediated gene transfer of active transforming growth factor- beta1 induces prolonged severe fibrosis in rat lung
    • Sime PJ, Xing Z, Graham FL, Csaky KG, Gauldie J (1997) Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung. J Clin Invest 100: 768-776. (Pubitemid 27371693)
    • (1997) Journal of Clinical Investigation , vol.100 , Issue.4 , pp. 768-776
    • Sime, P.J.1    Xing, Z.2    Graham, F.L.3    Csaky, K.G.4    Gauldie, J.5
  • 55
    • 38449101147 scopus 로고    scopus 로고
    • TGF-beta1 induces progressive pleural scarring and subpleural fibrosis
    • Decologne N, Kolb M, Margetts PJ, Menetrier F, Artur Y, et al. (2007) TGF-beta1 induces progressive pleural scarring and subpleural fibrosis. J Immunol 179: 6043-6051.
    • (2007) J Immunol , vol.179 , pp. 6043-6051
    • Decologne, N.1    Kolb, M.2    Margetts, P.J.3    Menetrier, F.4    Artur, Y.5
  • 56
    • 77957840310 scopus 로고    scopus 로고
    • Overexpression of transforming growth factor-beta1 in fetal monkey lung results in prenatal pulmonary fibrosis
    • Tarantal AF, Chen H, Shi TT, Lu CH, Fang AB, et al. (2010) Overexpression of transforming growth factor-beta1 in fetal monkey lung results in prenatal pulmonary fibrosis. Eur Respir J 36: 907-914.
    • (2010) Eur Respir J , vol.36 , pp. 907-914
    • Tarantal, A.F.1    Chen, H.2    Shi, T.T.3    Lu, C.H.4    Fang, A.B.5
  • 57
    • 0037144530 scopus 로고    scopus 로고
    • Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways
    • Lee CG, Homer RJ, Cohn L, Link H, Jung S, et al. (2002) Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways. J Biol Chem 277: 35466-35474.
    • (2002) J Biol Chem , vol.277 , pp. 35466-35474
    • Lee, C.G.1    Homer, R.J.2    Cohn, L.3    Link, H.4    Jung, S.5
  • 58
    • 79955005448 scopus 로고    scopus 로고
    • New concepts of IL-10-induced lung fibrosis: Fibrocyte recruitment and M2 activation in a CCL2/CCR2 axis
    • Sun L, Louie MC, Vannella KM, Wilke CA, LeVine AM, et al. (2011) New concepts of IL-10-induced lung fibrosis: fibrocyte recruitment and M2 activation in a CCL2/CCR2 axis. Am J Physiol Lung Cell Mol Physiol 300: L341-353.
    • (2011) Am J Physiol Lung Cell Mol Physiol , vol.300
    • Sun, L.1    Louie, M.C.2    Vannella, K.M.3    Wilke, C.A.4    LeVine, A.M.5
  • 62
    • 78149483354 scopus 로고    scopus 로고
    • CD4+CD25+Foxp3+ regulatory T cells depletion may attenuate the development of silica-induced lung fibrosis in mice
    • Liu F, Liu J, Weng D, Chen Y, Song L, et al. (2010) CD4+CD25+Foxp3+ regulatory T cells depletion may attenuate the development of silica-induced lung fibrosis in mice. PLoS One 5: e15404.
    • (2010) PLoS One , vol.5
    • Liu, F.1    Liu, J.2    Weng, D.3    Chen, Y.4    Song, L.5
  • 66
    • 84862150233 scopus 로고    scopus 로고
    • IL-17 neutralization significantly ameliorates hepatic granulomatous inflammation and liver damage in Schistosoma japonicum infected mice
    • Zhang Y, Chen L, Gao W, Hou X, Gu Y, et al. (2012) IL-17 neutralization significantly ameliorates hepatic granulomatous inflammation and liver damage in Schistosoma japonicum infected mice. Eur J Immunol 42: 1523-1535.
    • (2012) Eur J Immunol , vol.42 , pp. 1523-1535
    • Zhang, Y.1    Chen, L.2    Gao, W.3    Hou, X.4    Gu, Y.5
  • 67
    • 84894035265 scopus 로고    scopus 로고
    • Neutralization of interleukin-17A delays progression of silica-induced lung inflammation and fibrosis in C57BL/6 mice
    • Chen Y, Li C, Weng D, Song L, Tang W, et al. (2014) Neutralization of interleukin-17A delays progression of silica-induced lung inflammation and fibrosis in C57BL/6 mice. Toxicol Appl Pharmacol 275: 62-72.
    • (2014) Toxicol Appl Pharmacol , vol.275 , pp. 62-72
    • Chen, Y.1    Li, C.2    Weng, D.3    Song, L.4    Tang, W.5
  • 69
    • 0029881638 scopus 로고    scopus 로고
    • IL-1 receptor antagonist (IL-1ra) expression, function, and cytokine-mediated regulation during mycobacterial and schistosomal antigen-elicited granuloma formation
    • Ruth JH, Bienkowski M, Warmington KS, Lincoln PM, Kunkel SL, et al. (1996) IL-1 receptor antagonist (IL-1ra) expression, function, and cytokine-mediated regulation during mycobacterial and schistosomal antigen-elicited granuloma formation. J Immunol 156: 2503-2509.
    • (1996) J Immunol , vol.156 , pp. 2503-2509
    • Ruth, J.H.1    Bienkowski, M.2    Warmington, K.S.3    Lincoln, P.M.4    Kunkel, S.L.5
  • 70
    • 68649088121 scopus 로고    scopus 로고
    • Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity
    • Sutton CE, Lalor SJ, Sweeney CM, Brereton CF, Lavelle EC, et al. (2009) Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity 31: 331-341.
    • (2009) Immunity , vol.31 , pp. 331-341
    • Sutton, C.E.1    Lalor, S.J.2    Sweeney, C.M.3    Brereton, C.F.4    Lavelle, E.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.