Ozone exposure of macrophages induces an alveolar epithelial chemokine response through IL-1α

American Journal of Respiratory Cell and Molecular Biology

Volumn 38, Issue 3, 2008, Pages 318-323

  Manzer, Rizwan ^a   Dinarello, Charles A ^b   McConville, Glen ^a   Mason, Robert J ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Alveolar epithelial cells; Cell cell interactions; Cytokine induced neutrophil chemoattractant; IL 1 ; Monocyte chemoattractant protein 1

Indexed keywords

BIOLOGICAL MARKER; CHEMOKINE; CXCL1 CHEMOKINE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; RECOMBINANT INTERLEUKIN 1ALPHA; OZONE; RECOMBINANT PROTEIN;

AIR POLLUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CELL INTERACTION; CELL LINE; CELL TYPE; LUNG ALVEOLUS EPITHELIUM; MACROPHAGE; MALE; NONHUMAN; OZONE DEPLETION; PROTEIN SECRETION; RAT; ANIMAL; BIOLOGICAL MODEL; CULTURE MEDIUM; CULTURE TECHNIQUE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; EPITHELIUM CELL; GENETICS; GERMFREE ANIMAL; LUNG ALVEOLUS; LUNG ALVEOLUS MACROPHAGE; METABOLISM; SECRETION; SPRAGUE DAWLEY RAT; STATISTICS; TIME;

RATTUS;

ANIMALS; CELL CULTURE TECHNIQUES; CELL LINE; CHEMOKINE CCL2; CHEMOKINE CXCL1; CHEMOKINES; CULTURE MEDIA, CONDITIONED; CULTURE MEDIA, SERUM-FREE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; INTERLEUKIN-1ALPHA; MACROPHAGES, ALVEOLAR; MALE; MODELS, BIOLOGICAL; OZONE; PULMONARY ALVEOLI; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SPECIFIC PATHOGEN-FREE ORGANISMS; STATISTICS AS TOPIC; TIME FACTORS;

EID: 40649124756     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2007-0250OC     Document Type: Article

References (31)

1. Uysal N, Schapira RM. Effects of ozone on lung function and lung diseases. Curr Opin Pulm Med 2003;9:144-150.
2. Harkema JR, Wagner JG. Epithelial and inflammatory responses in the airways of laboratory rats coexposed to ozone and biogenic substances: enhancement of toxicant-induced airway injury. Exp Toxicol Pathol 2005;57:129-141.
3. Pino MV, Levin JR, Stovall MY, Hyde DM. Pulmonary inflammation and epithelial injury in response to acute ozone exposure in the rat. Toxicol Appl Pharmacol 1992;112:64-72.
4. Takahashi N, Yu XY, Schofield BH, Kleeberger SR, Scott AL, Hasegawa S, Spannhake EW. Expression of ICAM-1 in airway epithelium after acute ozone exposure in the mouse. J Appl Physiol 1995;79:1753-1761.
5. Haddad EB, Salmon M, Koto H, Barnes PJ, Adcock I, Chung KF. Ozone induction of cytokine-induced neutrophil chemoattractant (CINC) and nuclear factor-kappa b in rat lung: inhibition by corticosteroids. FEBS Lett 1996;379:265-268.
6. Koto H, Salmon M, Haddad EB, Huang TJ, Zagorski J, Chung KF. Role of cytokine-induced neutrophil chemoattractant (CINC) in ozone-induced airway inflammation and hyperresponsiveness. Am J Respir Crit Care Med 1997;156:234-239.
7. Pryor WA. How far does ozone penetrate into the pulmonary air/tissue boundary before it reacts? Free Radic Biol Med 1992;12:83-88.
8. Wang J, Wang S, Manzer R, McConville G, Mason RJ. Ozone induces oxidative stress in rat alveolar type II and type I-like cells. Free Radic Biol Med 2006;40:1914-1928.
9. Zhao Q, Simpson LG, Driscoll KE, Leikauf GD. Chemokine regulation of ozone-induced neutrophil and monocyte inflammation. Am J Physiol 1998;274:L39-L46.
10. Manzer R, Wang J, Nishina K, McConville G, Mason RJ. Alveolar epithelial cells secrete chemokines in response to IL-1beta and lipopolysaccharide but not to ozone. Am J Respir Cell Mol Biol 2006;34:158-166.
11. Janic B, Umstead TM, Phelps DS, Floros J. Modulatory effects of ozone on THP-1 cells in response to SP-A stimulation. Am J Physiol Lung Cell Mol Physiol 2005;288:L317-L325.
12. Devlin RB, McKinnon KP, Noah T, Becker S, Koren HS. Ozone-induced release of cytokines and fibronectin by alveolar macrophages and airway epithelial cells. Am J Physiol 1994;266:L612-L619.
13. Jaspers I, Chen LC, Flescher E. Induction of interleukin-8 by ozone is mediated by tyrosine kinase and protein kinase A, but not by protein kinase C. J Cell Physiol 1998;177:313-323.
14. Nichols BG, Woods JS, Luchtel DL, Corral J, Koenig JQ. Effects of ozone exposure on nuclear factor-kappaB activation and tumor necrosis factor-alpha expression in human nasal epithelial cells. Toxicol Sci 2001;60:356-362.
15. Rusznak C, Devalia JL, Sapsford RJ, Davies RJ. Ozone-induced mediator release from human bronchial epithelial cells in vitro and the influence of nedocromil sodium. Eur Respir J 1996;9:2298-2305.
16. Pearson AC, Bhalla DK. Effects of ozone on macrophage adhesion in vitro and epithelial and inflammatory responses in vivo: the role of cytokines. J Toxicol Environ Health 1997;50:143-157.
17. Dobbs LG, Mason RJ. Pulmonary alveolar type II cells isolated from rats. Release of phosphatidylcholine in response to beta-adrenergic stimulation. J Clin Invest 1979;63:378-387.
18. Allen CB. An automated system for exposure of cultured cells and other materials to ozone. Inhal Toxicol 2003;15:1039-1052.
19. Portnoy J, Pan T, Dinarello CA, Shannon JM, Westcott JY, Zhang L, Mason RJ. Alveolar type II cells inhibit fibroblast proliferation: role of IL-1alpha. Am J Physiol Lung Cell Mol Physiol 2006;290:L307-L316.
20. Chang MM, Wu R, Plopper CG, Hyde DM. IL-8 is one of the major chemokines produced by monkey airway epithelium after ozone-induced injury. Am J Physiol 1998;275:L524-L532.
21. Michalec L, Choudhury BK, Postlethwait E, Wild JS, Alam R, Lett-Brown M, Sur S. CCL7 and CXCL10 orchestrate oxidative stress-induced neutrophilic lung inflammation. J Immunol 2002;168:846-852.
22. Park JW, Taube C, Swasey C, Kodama T, Joetham A, Balhorn A, Takeda K, Miyahara N, Allen CB, Dakhama A, et al. Interleukin-1 receptor antagonist attenuates airway hyperresponsiveness following exposure to ozone. Am J Respir Cell Mol Biol 2004;30:830-836.
23. Johnston CJ, Stripp BR, Reynolds SD, Avissar NE, Reed CK, Finkelstein JN. Inflammatory and antioxidant gene expression in C57BL/6J mice after lethal and sublethal ozone exposures. Exp Lung Res 1999;25:81-97.
24. Ishii Y, Yang H, Sakamoto T, Nomura A, Hasegawa S, Hirata F, Bassett DJ. Rat alveolar macrophage cytokine production and regulation of neutrophil recruitment following acute ozone exposure. Toxicol Appl Pharmacol 1997;147:214-223.
25. Mosley B, Urdal DL, Prickett KS, Larsen A, Cosman D, Conlon PJ, Gillis S, Dower SK. The interleukin-1 receptor binds the human interleukin-1 alpha precursor but not the interleukin-1 beta precursor. J Biol Chem 1987;262:2941-2944.
26. Dinarello CA. Biologic basis for interleukin-1 in disease. Blood 1996;87:2095-2147.
27. Hogquist KA, Nett MA, Unanue ER, Chaplin DD. Interleukin 1 is processed and released during apoptosis. Proc Natl Acad Sci USA 1991;88:8485-8489.
28. Niki Y, Yamada H, Kikuchi T, Toyama Y, Matsumoto H, Fujikawa K, Tada N. Membrane-associated IL-1 contributes to chronic synovitis and cartilage destruction in human IL-1 alpha transgenic mice. J Immunol 2004;172:577-584.
29. Nakane T, Szentendrei T, Stern L, Virmani M, Seely J, Kunos G. Effects of IL-1 and cortisol on beta-adrenergic receptors, cell proliferation, and differentiation in cultured human A549 lung tumor cells. J Immunol 1990;145:260-266.
30. Matta SG, Linner KM, Sharp BM. Interleukin-1 alpha and interleukin-1 beta stimulate adrenocorticotropin secretion in the rat through a similar hypothalamic receptor(s): effects of interleukin-1 receptor antagonist protein. Neuroendocrinology 1993;57:14-22.
31. Chen CJ, Kono H, Golenbock D, Reed G, Akira S, Rock KL. Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat Med 2007;13:851-856.