IL-1a released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts

Mucosal Immunology

Volumn 7, Issue 3, 2014, Pages 684-693

  Suwara, M I ^a   Green, N J ^a   Borthwick, L A ^a   Mann, J ^a   Mayer Barber, K D ^b   Barron, L ^b   Corris, P A ^a   Farrow, S N ^c   Wynn, T A ^b   Fisher, A J ^a   Mann, D A ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; DOUBLE STRANDED RNA; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 ANTIBODY; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL LIKE RECEPTOR 3; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; AUTACOID; CULTURE MEDIUM; CYTOKINE; INTERLEUKIN 1 RECEPTOR TYPE I;

ANIMAL CELL; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CULTURE MEDIUM; DISEASE EXACERBATION; ENDOPLASMIC RETICULUM STRESS; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOREGULATION; INFLAMMATION; INNATE IMMUNITY; LUNG DISEASE; LUNG FIBROBLAST; LUNG LAVAGE; MOUSE; NEUTROPHILIA; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CELL LINE; DISEASE MODEL; DRUG EFFECTS; FIBROBLAST; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHARMACOLOGY; PNEUMONIA; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; CYTOKINES; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM STRESS; EPITHELIAL CELLS; FIBROBLASTS; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-1ALPHA; MICE; MICE, KNOCKOUT; NF-KAPPA B; OXIDATIVE STRESS; PHENOTYPE; PNEUMONIA; RECEPTORS, INTERLEUKIN-1 TYPE I; SIGNAL TRANSDUCTION;

EID: 84899507007     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2013.87     Document Type: Article

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