Neutralization of interleukin-1 beta attenuates silica-induced lung inflammation and fibrosis in C57BL/6 mice

Archives of Toxicology

Volumn 87, Issue 11, 2013, Pages 1963-1973

  Guo, Jiali ^a   Gu, Nali ^a   Chen, Jie ^b   Shi, Tingming ^c   Zhou, Yun ^a   Rong, Yi ^a   Zhou, Ting ^a   Yang, Wenxiang ^c   Cui, Xiuqing ^a   Chen, Weihong ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b CHINA MEDICAL UNIVERSITY   (China)

^c Hubei Center for Animal Disease Control and Prevention   (China)

Author keywords

IL 1 ; Lung fibrosis; Lung inflammation; Silica

Indexed keywords

COLLAGEN TYPE 1; FIBRONECTIN; INTERLEUKIN 1BETA; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1; SILICON DIOXIDE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CELLULAR IMMUNITY; CONTROLLED STUDY; EXPOSURE; GENE EXPRESSION; HISTOPATHOLOGY; LUNG FIBROSIS; LUNG LAVAGE; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PNEUMONIA; PRIORITY JOURNAL; PROTEIN DEPLETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SILICOSIS; TH1 TH2 BALANCE;

MUS;

ANIMALS; ANTIBODIES, BLOCKING; ANTIBODIES, MONOCLONAL; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; COLLAGEN TYPE I; FIBRONECTINS; INTERLEUKIN-1BETA; LUNG; MALE; MICE; MICE, INBRED C57BL; PULMONARY ALVEOLI; PULMONARY FIBROSIS; SILICON DIOXIDE; SILICOSIS; TH1-TH2 BALANCE; TRANSFORMING GROWTH FACTOR BETA;

EID: 84885949158     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-013-1063-z     Document Type: Article

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