Development of an in vitro corrosion/irritation prediction assay using the EpiDerm™ skin model

Toxicology in Vitro

Volumn 21, Issue 7, 2007, Pages 1292-1297

  Kidd, D A ^a,b   Johnson, M ^a   Clements, J ^a  

^a UK   (United Kingdom)

^b UNIVERSITY OF YORK   (United Kingdom)

Author keywords

Corrosion; EpiDerm ; IL 1 ; Irritation; MTT

Indexed keywords

ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; CORROSION; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; SENSITIVITY ANALYSIS; SKIN SENSITIVITY; SKIN TEST;

CAUSTICS; CELL SURVIVAL; EPIDERMIS; FORECASTING; HUMANS; INTERLEUKIN-1; IRRITANTS; REPRODUCIBILITY OF RESULTS; SKIN IRRITANCY TESTS; TIME FACTORS;

EID: 35648993007     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.08.018     Document Type: Article

References (23)

1. Basketter D.A., York M., McFadden J.P., and Robinson M.K. Determination of skin irritation potential in the human 4 h patch test. Contact Dermatitis 51 (2004) 1-4
2. Botham P.A., Earl L.K., Fentem J.H., Roguet R., and van de Sandt J.J.M. Alternative methods for skin irritation testing: the current status ECVAM skin irritation task force report 1. Alternatives to Laboratory Animals 26 (1998) 195-211
3. Cannon C.L., Neal P.J., Southee J.A., Kubilus J., and Klausner M. New epidermal model for dermal irritancy testing. Toxicology in Vitro 8 (1994) 889-891
4. Coquette A., Berna N., Vandenbosch A., Rosdy M., De Wever B., and Poumay Y. Analysis of interleukin-1α (IL-1α) and interleukin-8 (IL-8) expression and release in in vitro reconstructed human epidermis for the prediction of in vivo skin irritation and/or sensitization. Toxicology in Vitro 17 (2003) 311-321
5. Cotovio J., Grandidier M.H., Portes P., Roguet R., and Rubinstenn G. The in vitro skin irritation of chemicals: optimisation of the EPISKIN prediction model within the framework of the ECVAM validation process. Alternatives to Laboratory Animals 33 (2005) 329-349
6. Draize J.H., Woodard G., and Calvery H.O. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. Journal of Pharmacology and Experimental Therapeutics 82 (1944) 377-390
7. Faller C., Bracher M., Dami N., and Roguet R. Predictive ability of reconstructed human epidermis equivalents for the assessment of skin irritation of cosmetics. Toxicology in Vitro 16 (2002) 557-572
8. Fentem J.H., and Botham P.A. ECVAM's activities in validating alternative tests for skin corrosion and irritation. Alternatives to Laboratory Animals 30 Suppl. 2 (2002) 61-67
9. Fentem J.H., Archer G.E.B., Balls M., Botham P.A., Curren R.D., Earl L.K., Esdaile D.J., Holzhütter H.-G., and Liebsch M. The ECVAM international validation study on in vitro tests for skin corrosivity. 2. Results and evaluation by the management team. Toxicology in Vitro 12 (1998) 483-524
10. Fentem J.H., Briggs D., Chesné C., Elliott G.R., Harbell J.W., Heylings J.R., Portes P., Roguet R., van de Sandt J.J.M., and Botham P.A. A prevalidation study on in vitro tests for acute skin irritation: results and evaluation by the management team. Toxicology in Vitro 15 (2001) 57-93
11. Heylings J.R., Diot S., Esdaile D.J., Fasano W.J., Manning L.A., and Owen H.M. A prevalidation study on the in vitro skin irritation function test (SIFT) for prediction of acute skin irritation in vivo: results and evaluation of ECVAM phase III. Toxicology in Vitro 17 (2003) 123-138
12. Kandárová H., Liebsch M., Genschow E., Gerner I., Traue D., Slawik B., and Spielmann H. Optimisation of the EpiDerm test protocol for the upcoming ECVAM validation study on in vitro skin irritation tests. ALTEX 21 (2004) 107-114
13. Kandárová H., Liebsch M., Gerner I., Schmidt E., Genschow E., Traue D., and Spielmann H. The EpiDerm test protocol for the upcoming ECVAM validation study on in vitro skin irritation tests - an assessment of the performance of the optimised test. Alternatives to Laboratory Animals 33 (2005) 351-367
14. Kandárová H., Liebsch M., Schmidt E., Genschow E., Traue D., Spielmann H., Meyer K., Steinhoff C., Tornier C., De Wever B., and Rosdy M. Assessment of the skin irritation potential of chemicals by using the skinethic reconstructed human epidermal model and the common skin irritation potential evaluated in the ECVAM skin irritation validation study. Alternatives to Laboratory Animals 34 (2006) 393-406
15. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunological Methods 65 (1983) 6-24
16. OECD, 1992. OECD Guideline for Testing of Chemicals, No. 404: Acute Dermal Irritation/Corrosion. Organisation for Economic Cooperation and Development, Paris.
17. OECD, 2002. OECD Draft Guideline for the Testing of Chemicals, 431. In Vitro Skin Corrosion: Human Skin Model Test. Organisation for Economic Cooperation and Development, Paris.
18. OECD, 2004. OECD Guideline for the Testing of Chemicals, 431. In Vitro Skin Corrosion: Human Skin Model Test. Organisation for Economic Cooperation and Development, Paris.
19. Ponec M., Boelsma E., Weerheim A., Mulder A., Bouwstra J., and Mommaas M. Lipid and ultrastructural characterization of reconstructed skin models. International Journal of Pharmaceutics 203 (2000) 211-225
20. ® protocol for the assessment of acute skin irritation of chemicals: follow-up to the ECVAM prevalidation study. Toxicology in Vitro 16 (2002) 765-770
21. Robinson M.K., Osbourne R., and Perkins M.A. Strategies for the assessment of acute skin irritation potential. Journal of Pharmacological and Toxicological Methods 42 (1999) 1-9
22. Tornier C., Rosdy M., and Maibach H.I. In vitro skin irritation testing on reconstituted human epidermis: reproducibility for 50 chemicals tested with two protocols. Toxicology in Vitro 20 (2006) 401-416
23. Zuang V., Balls M., Botham P.A., Coquette A., Corsini E., Curren R.D., Elliot G.R., Fentem J.H., Heylings J.R., Liebsch M., Medina J., Roguet R., van de Sandt J.J.M., Wiemann C., and Worth A.P. Follow-up to the ECVAM prevalidation study on in vitro tests for acute skin irritation. Alternatives to Laboratory Animals 30 (2002) 109-129