IKKα negatively regulates ASC-dependent inflammasome activation

Nature Communications

Volumn 5, Issue , 2014, Pages

  Martin, Bradley N ^a,b   Wang, Chenhui ^a   Willette Brown, Jami ^c   Herjan, Tomasz ^a   Gulen, Muhammet F ^a   Zhou, Hao ^a   Bulek, Katarzyna ^a   Franchi, Luigi ^d   Sato, Takashi ^c   Alnemri, Emad S ^e   Narla, Goutham ^b   Zhong, Xiao Ping ^f   Thomas, James ^g   Klinman, Dennis ^c   Fitzgerald, Katherine A ^h   Karin, Michael ⁱ   Nuñez, Gabriel ^d   Dubyak, George ^b   Hu, Yinling ^c   Li, Xiaoxia ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e THOMAS JEFFERSON UNIVERSITY   (United States)

^f DUKE UNIVERSITY MEDICAL CENTER   (United States)

^g BAYLOR COLLEGE OF MEDICINE   (United States)

^h UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; I KAPPA B KINASE ALPHA; INFLAMMASOME; APOPTOSIS REGULATORY PROTEIN; CARRIER PROTEIN; CHUK PROTEIN, MOUSE; CIAS1 PROTEIN, MOUSE; I KAPPA B KINASE; IKBKE PROTEIN, MOUSE; PYCARD PROTEIN, MOUSE;

APOPTOSIS; ENZYME ACTIVITY; GENE EXPRESSION; IMMUNE RESPONSE; PROTEIN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; FEMALE; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANIMAL; DOWN REGULATION; GENETICS; KNOCKOUT MOUSE; MALE; METABOLISM; PROTEIN TRANSPORT;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CARRIER PROTEINS; DOWN-REGULATION; FEMALE; I-KAPPA B KINASE; INFLAMMASOMES; MACROPHAGES; MALE; MICE; MICE, KNOCKOUT; PROTEIN TRANSPORT;

EID: 84923335884     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5977     Document Type: Article

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