Abnormal Morphogenesis but Intact IKK Activation in Mice Lacking the IKKα Subunit of IκB Kinase

Science

Volumn 284, Issue 5412, 1999, Pages 316-320

  Hu, Yinling ^a   Baud, Véronique ^a   Delhase, Mireille ^a   Zhang, Peilin ^b   Deerinck, Thomas ^c   Ellisman, Mark ^c   Karin, Michael ^a   Johnson, Randall ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHUK PROTEIN, MOUSE; DNA BINDING PROTEIN; I KAPPA B; I KAPPA B KINASE; IKBKB PROTEIN, MOUSE; IKBKE PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE;

ANIMAL; APOPTOSIS; ARTICLE; BONE; CELL CULTURE; CELL DIFFERENTIATION; CELL NUCLEUS; CHEMISTRY; CONGENITAL MALFORMATION; CONGENITAL SKIN DISEASE; CYTOLOGY; DIMERIZATION; ENZYME ACTIVATION; ENZYMOLOGY; EPIDERMIS; FEMALE; GENE TARGETING; GENETICS; KERATINOCYTE; LIMB MALFORMATION; MALE; METABOLISM; MORPHOGENESIS; MOUSE; MULTIPLE MALFORMATION SYNDROME; MUTATION; PHOSPHORYLATION; PRENATAL DEVELOPMENT; SKIN;

ABNORMALITIES, MULTIPLE; ANIMALS; APOPTOSIS; BODY PATTERNING; BONE AND BONES; CELL DIFFERENTIATION; CELL NUCLEUS; CELLS, CULTURED; DIMERIZATION; DNA-BINDING PROTEINS; EMBRYONIC AND FETAL DEVELOPMENT; ENZYME ACTIVATION; EPIDERMIS; FEMALE; GENE TARGETING; I-KAPPA B KINASE; I-KAPPA B PROTEINS; KERATINOCYTES; LIMB DEFORMITIES, CONGENITAL; MALE; MICE; MORPHOGENESIS; MUTATION; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SKIN; SKIN ABNORMALITIES;

EID: 0033537767     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.284.5412.316     Document Type: Article

References (3)

1. P. A. Baeuerle, and D. Baltimore, Cell 87, 13 (1996);
2. I. M. Verma, J. K. Stevenson, E. M. Schwarz, D. Van Antwerp, S. Miyamoto, Genes Dev. 9, 2723 (1995);
3. A. A. Beg and A. S. Baldwin Jr., ibid. 7, 2064 (1993).