The therapeutic effects of 4-phenylbutyric acid in maintaining proteostasis

International Journal of Biochemistry and Cell Biology

Volumn 61, Issue , 2015, Pages 45-52

  Kolb, P S ^a   Ayaub, E A ^a,b   Zhou, W ^a   Yum, V ^a,c   Dickhout, J G ^a,c   Ask, K ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c Hamilton Centre for Kidney Research   (Canada)

Author keywords

4 PBA; 4 Phenylbutyric acid; ER stress; UPR

Indexed keywords

4 PHENYLBUTYRIC ACID; 4-PHENYLBUTYRIC ACID; ARYLBUTYRIC ACID DERIVATIVE;

CELL DEATH; CONNECTIVE TISSUE DISEASE; DRUG EFFECT; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; FIBROSIS; GENETIC DISORDER; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY DISEASE; MEDICAL RESEARCH; METABOLIC SYNDROME X; NEOPLASM; NEUROLOGIC DISEASE; NONHUMAN; PROTEIN HOMEOSTASIS; REVIEW; ANIMAL; DRUG EFFECTS; ENDOPLASMIC RETICULUM; HOMEOSTASIS; METABOLISM; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; UREA CYCLE DISORDERS, INBORN;

ANIMALS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HOMEOSTASIS; HUMANS; PHENYLBUTYRATES; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; UREA CYCLE DISORDERS, INBORN;

EID: 84922748910     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2015.01.015     Document Type: Review

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