No amelioration of uromodulin maturation and trafficking defect by sodium 4-phenylbutyrate in vivo: Studies in mouse models of uromodulin-associated kidney disease

Journal of Biological Chemistry

Volumn 289, Issue 15, 2014, Pages 10715-10726

  Kemter, Elisabeth ^a   Sklenak, Stefanie ^a   Rathkolb, Birgit ^a,b   De Angelis, Martin Hrabě ^b   Wolf, Eckhard ^a   Aigner, Bernhard ^a   Wanke, Ruediger ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; DEFECTS; IODINE; SODIUM;

CHEMICAL CHAPERONE; CURRENT TREATMENTS; DISEASE PROGRESSION; EPITHELIAL CELLS; EXPRESSION LEVELS; HSP70 EXPRESSION; KIDNEY FUNCTION; THERAPEUTIC INTERVENTION;

MAMMALS;

4-PBA; ENDOPLASMIC RETICULUM STRESS; GENETIC DISEASES; HISTONE DEACETYLASE INHIBITORS; KIDNEY; MOLECULAR CHAPERONE; NF-ΚB (NF-KB); RELB; UAKD; UROMODULIN (UMOD);

ANIMALS; CYTOPLASM; DISEASE MODELS, ANIMAL; GOUT; HOMOZYGOTE; HSP70 HEAT-SHOCK PROTEINS; HYPERURICEMIA; KIDNEY; KIDNEY DISEASES; KIDNEY TUBULES; MALE; MICE; MOLECULAR CHAPERONES; MUTAGENESIS; MUTATION; NF-KAPPA B; PHENOTYPE; PHENYLBUTYRATES; PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELB; UROMODULIN;

EID: 84898632703     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.537035     Document Type: Article

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