Mutations of rat surfactant protein A have distinct effects on its glycosylation, secretion, aggregation and degradation

Life Sciences

Volumn 117, Issue 2, 2014, Pages 47-55

  Yang, Wenbing ^a   Shen, Haitao ^a   Fang, Guodong ^a   Li, Hui ^a   Li, Lan ^a   Deng, Fang ^a   Gu, Wei ^a   Li, Kangsheng ^a   Ma, Lian ^b   Gu, Jiang ^a   Wang, Yongyu ^a  

^a SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

^b THE SECOND AFFILIATED HOSPITAL OF SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

Author keywords

Aggregation; Degradation; Familial pulmonary fibrosis; Glycosylation; Protein secretion; Surfactant protein A

Indexed keywords

SURFACTANT PROTEIN A; PRIMER DNA; PROTEIN AGGREGATE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CHO CELL LINE; GENE MUTATION; GENETIC TRANSFECTION; NONHUMAN; PLASMID; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN GLYCOSYLATION; PROTEIN SECRETION; PROTEIN STABILITY; RAT; SITE DIRECTED MUTAGENESIS; ANIMAL; CRICETULUS; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; GLYCOSYLATION; HAMSTER; IMMUNOBLOTTING; METABOLISM; MISSENSE MUTATION; PHENOTYPE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN CONFORMATION; SECRETION (PROCESS); WESTERN BLOTTING;

RATTUS;

ANIMALS; BLOTTING, WESTERN; CHO CELLS; CRICETINAE; CRICETULUS; DNA PRIMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLUORESCENT ANTIBODY TECHNIQUE; GLYCOSYLATION; IMMUNOBLOTTING; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; PHENOTYPE; PROTEIN AGGREGATES; PROTEIN CONFORMATION; PROTEOLYSIS; PULMONARY SURFACTANT-ASSOCIATED PROTEIN A; RATS;

EID: 84908450568     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2014.09.006     Document Type: Article

References (47)

1. R. Apweiler, H. Hermjakob, and N. Sharon On the frequency of protein glycosylation, as deduced from analysis of the SWISS-PROT database Biochim Biophys Acta 1473 1999 4 8
2. G. Ashwell, and J. Harford Carbohydrate-specific receptors of the liver Annu Rev Biochem 51 1982 531 554
3. M.F. Beers, M. Zhao, Y. Tomer, S.J. Russo, P. Zhang, and L.W. Gonzales Disruption of N-linked glycosylation promotes proteasomal degradation of the human ATP-binding cassette transporter ABCA3 Am J Physiol Lung Cell Mol Physiol 305 2013 L970 L980
4. P. Burda, and M. Aebi The dolichol pathway of N-linked glycosylation Biochim Biophys Acta 1426 1999 239 257
5. C.M. Cabral, Y. Liu, and R.N. Sifers Dissecting glycoprotein quality control in the secretory pathway Trends Biochem Sci 26 2001 619 624
6. S.A. Carr, M.E. Hemling, G. Folena-Wasserman, R.W. Sweet, K. Anumula, and J.R. Barr Protein and carbohydrate structural analysis of a recombinant soluble CD4 receptor by mass spectrometry J Biol Chem 264 1989 21286 21295
7. E. Crouch, K. Hartshorn, and I. Ofek Collectins and pulmonary innate immunity Immunol Rev 173 2000 52 65
8. C.M. Dobson Protein folding and misfolding Nature 426 2003 884 890
9. C.M. Dobson Principles of protein folding, misfolding and aggregation Semin Cell Dev Biol 15 2004 3 16
10. E. Gao, Y. Wang, S.M. McCormick, J. Li, S.R. Seidner, and C.R. Mendelson Characterization of two baboon surfactant protein A genes Am J Physiol 271 1996 L617 L630
11. I. Garcia-Verdugo, F. Sanchez-Barbero, F.U. Bosch, W. Steinhilber, and C. Casals Effect of hydroxylation and N187-linked glycosylation on molecular and functional properties of recombinant human surfactant protein A Biochemistry 42 2003 9532 9542
12. G. Gardian, S.E. Browne, D.K. Choi, P. Klivenyi, J. Gregorio, and J.K. Kubilus Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease J Biol Chem 280 2005 556 563
13. Q. Hang, Y. Zhou, S. Hou, D. Zhang, X. Yang, and J. Chen Asparagine-linked glycosylation of bone morphogenetic protein-2 is required for secretion and osteoblast differentiation Glycobiology 24 2014 292 304
14. B. Hansske, C. Thiel, T. Lubke, M. Hasilik, S. Honing, and V. Peters Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId J Clin Invest 109 2002 725 733
15. S.R. Haseley, P. Talaga, J.P. Kamerling, and J.F.G. Vliegenthart Characterization of the carbohydrate binding specificity and kinetic parameters of lectins by using surface plasmon resonance Anal Biochem 274 1999 203 210
16. Y. Ishida, A. Yamamoto, A. Kitamura, S.R. Lamande, T. Yoshimori, and J.F. Bateman Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection Mol Biol Cell 20 2009 2744 2754
17. R. Knauer, and L. Lehle The oligosaccharyltransferase complex from yeast Biochim Biophys Acta 1426 1999 259 273
18. J.G. Leroy Congenital disorders of N-glycosylation including diseases associated with O- as well as N-glycosylation defects Pediatr Res 60 2006 643 656
19. E. Martin-Rendon, and D.J. Blake Protein glycosylation in disease: new insights into the congenital muscular dystrophies Trends Pharmacol Sci 24 2003 178 183
20. F.X. McCormack, H.M. Calvert, P.A. Watson, D.L. Smith, R.J. Mason, and D.R. Voelker The structure and function of surfactant protein A. Hydroxyproline- and carbohydrate-deficient mutant proteins J Biol Chem 269 1994 5833 5841
21. S. Mimori, H. Ohtaka, Y. Koshikawa, K. Kawada, M. Kaneko, and Y. Okuma 4-Phenylbutyric acid protects against neuronal cell death by primarily acting as a chemical chaperone rather than histone deacetylase inhibitor Bioorg Med Chem Lett 23 2013 6015 6018
22. H. Nakagawa, K. Wakabayashi-Nakao, A. Tamura, Y. Toyoda, S. Koshiba, and T. Ishikawa Disruption of N-linked glycosylation enhances ubiquitin-mediated proteasomal degradation of the human ATP-binding cassette transporter ABCG2 FEBS J 276 2009 7237 7252
23. K. Osanai, C. Tsuchihara, R. Hatta, T. Oikawa, K. Tsuchihara, and M. Iguchi Pulmonary surfactant transport in alveolar type II cells Respirology 11 Suppl. 2006 S70 S73
24. N. Palaniyar, M. Ikegami, T. Korfhagen, J. Whitsett, and F.X. McCormack Domains of surfactant protein A that affect protein oligomerization, lipid structure and surface tension Comp Biochem Physiol A Mol Integr Physiol 129 2001 109 127
25. J.C. Paulson Glycoproteins: what are the sugar chains for? Trends Biochem Sci 14 1989 272 276
26. J. Peter-Katalinic Methods in enzymology: O-glycosylation of proteins Methods Enzymol 405 2005 139 171
27. R. Qiu, and F.E. Regnier Comparative glycoproteomics of N-linked complex-type glycoforms containing sialic acid in human serum Anal Chem 77 2005 7225 7231
28. K. Ray, P. Clapp, P.K. Goldsmith, and A.M. Spiegel Identification of the sites of N-linked glycosylation on the human calcium receptor and assessment of their role in cell surface expression and signal transduction J Biol Chem 273 1998 34558 34567
29. J. Roth, C. Zuber, S. Park, I. Jang, Y. Lee, and K.G. Kysela Protein N-glycosylation, protein folding, and protein quality control Mol Cells 30 2010 497 506
30. R.C. Rubenstein, M.E. Egan, and P.L. Zeitlin In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing delta F508-CFTR J Clin Invest 100 1997 2457 2465
31. D.C. Rubinsztein The roles of intracellular protein-degradation pathways in neurodegeneration Nature 443 2006 780 786
32. H. Ryu, K. Smith, S.I. Camelo, I. Carreras, J. Lee, and A.H. Iglesias Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice J Neurochem 93 2005 1087 1098
33. E.K. Schrader, K.G. Harstad, and A. Matouschek Targeting proteins for degradation Nat Chem Biol 5 2009 815 822
34. R.J. Sola, J.A. Rodriguez-Martinez, and K. Griebenow Modulation of protein biophysical properties by chemical glycosylation: biochemical insights and biomedical implications Cell Mol Life Sci 64 2007 2133 2152
35. Y. Song, G. Fang, H. Shen, H. Li, W. Yang, and B. Pan Human surfactant protein A2 gene mutations impair dimmer/trimer assembly leading to deficiency in protein sialylation and secretion PLoS One 7 2012 e46559
36. L. Suaud, K. Miller, A.E. Panichelli, R.L. Randell, C.M. Marando, and R.C. Rubenstein 4-Phenylbutyrate stimulates Hsp70 expression through the Elp2 component of elongator and STAT-3 in cystic fibrosis epithelial cells J Biol Chem 286 2011 45083 45092
37. E.S. Trombetta, K.G. Fleming, and A. Helenius Quaternary and domain structure of glycoprotein processing glucosidase II Biochemistry 40 2001 10717 10722
38. F.M. Tuccillo, A. de Laurentiis, C. Palmieri, G. Fiume, P. Bonelli, and A. Borrelli Aberrant glycosylation as biomarker for cancer: focus on CD43 BioMed Res Int 2014 2014 742831
39. J. Tyedmers, A. Mogk, and B. Bukau Cellular strategies for controlling protein aggregation Nat Rev Mol Cell Biol 11 2010 777 788
40. A. Varki Sialic acids in human health and disease Trends Mol Med 14 2008 351 360
41. S.S. Vembar, and J.L. Brodsky One step at a time: endoplasmic reticulum-associated degradation Nat Rev Mol Cell Biol 9 2008 944 957
42. Y. Wang, P.J. Kuan, C. Xing, J.T. Cronkhite, F. Torres, and R.L. Rosenblatt Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer Am J Hum Genet 84 2009 52 59
43. P.H. Weigel, and J.H. Yik Glycans as endocytosis signals: the cases of the asialoglycoprotein and hyaluronan/chondroitin sulfate receptors Biochim. Biophys Acta 1572 2002 341 363
44. R.T. White, D. Damm, J. Miller, K. Spratt, J. Schilling, and S. Hawgood Isolation and characterization of the human pulmonary surfactant apoprotein gene Nature 317 1985 361 363
45. J.R. Wright Immunoregulatory functions of surfactant proteins Nat Rev Immunol 5 2005 58 68
46. P. Wujek, E. Kida, M. Walus, K.E. Wisniewski, and A.A. Golabek N-glycosylation is crucial for folding, trafficking, and stability of human tripeptidyl-peptidase I J Biol Chem 279 2004 12827 12839
47. P.L. Zeitlin Pharmacologic restoration of delta F508 CFTR-mediated chloride current Kidney Int 57 2000 832 837