Sodium 4-phenylbutyrate ameliorates the effects of cataractcausing mutant gammaD-crystallin in cultured cells

Molecular Vision

Volumn 16, Issue , 2010, Pages 997-1003

  Gong, Bo ^a   Zhang, Li Yun ^a,b   Lam, Dennis Shun Chiu ^a   Pang, Chi Pui ^a   Yam, Gary Hin Fai ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 PHENYLBUTYRIC ACID; CHAPERONE; DIMETHYL SULFOXIDE; GAMMA CRYSTALLIN; GAMMAD CRYSTALLIN; GLYCEROL; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; MUTANT PROTEIN; TRIMETHYLAMINE OXIDE; TRITON X 100; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CATARACT; CELL NUCLEUS MEMBRANE; CELL STRAIN COS7; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; GENE EXPRESSION; GENE MUTATION; IMMUNOFLUORESCENCE TEST; MOLECULAR SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOLUBILITY; UPREGULATION; WESTERN BLOTTING; WILD TYPE;

ANIMALS; APOPTOSIS; CATARACT; CERCOPITHECUS AETHIOPS; COS CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; GAMMA-CRYSTALLINS; HSP70 HEAT-SHOCK PROTEINS; MUTATION; NUCLEAR ENVELOPE; PHENOTYPE; PHENYLBUTYRATES; SOLUBILITY; TISSUE DISTRIBUTION; TRANSFECTION; UP-REGULATION;

EID: 77955595596     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

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