Defective trafficking of cone photoreceptor CNG channels induces the unfolded protein response and ER-stress-associated cell death

Biochemical Journal

Volumn 441, Issue 2, 2012, Pages 685-696

  Duricka, Deborah L ^a   Brown, R Lane ^a   Varnum, Michael D ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Chaperone; Ion channel subunit; Membrane localization; Misfolding; Retinal disease; Unfolded protein response (UPR)

Indexed keywords

4 PHENYLBUTYRIC ACID; 8(4 CHLOROPHENYLTHIO) CGMP; CYCLIC GMP; CYCLIC NUCLEOTIDE GATED CHANNEL; CYCLIC NUCLEOTIDE GATED CHANNEL A3; TAUROURSODEOXYCHOLATE SODIUM SALT; TAUROURSODEOXYCHOLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL MEMBRANE; CELL MIGRATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; GENE MUTATION; IMMUNOBLOTTING; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; RETINA CONE; UNFOLDED PROTEIN RESPONSE;

ANIMALS; CELL DEATH; CELL LINE; CELL MEMBRANE; CYCLIC GMP; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; ENDOPLASMIC RETICULUM; HEAT-SHOCK PROTEINS; HUMANS; MICE; MOLECULAR CHAPERONES; PROTEIN TRANSPORT; RETINAL CONE PHOTORECEPTOR CELLS; TRANSCRIPTION FACTOR CHOP; UNFOLDED PROTEIN RESPONSE;

EID: 84555189151     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111004     Document Type: Article

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