Integrative proteomics and targeted transcriptomics analyses in cardiac endothelial cells unravel mechanisms of long-term radiation-induced vascular dysfunction

Journal of Proteome Research

Volumn 14, Issue 2, 2015, Pages 1203-1219

  Azimzadeh, Omid ^a   Sievert, Wolfgang ^a,b   Sarioglu, Hakan ^a   Merl Pham, Juliane ^a   Yentrapalli, Ramesh ^a   Bakshi, Mayur V ^a   Janik, Dirk ^a   Ueffing, Marius ^a,c   Atkinson, Michael J ^a,d   Multhoff, Gabriele ^a,b   Tapio, Soile ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

cardiovascular disease; endothelial cell; endothelial cell dysfunction; heart; ICPL; insulin; Ionizing radiation; PI3K; PPAR alpha; proteomics

Indexed keywords

CD31 ANTIGEN; CELL SURFACE MARKER; INSULIN; ISOTOPE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEOME; SOMATOMEDIN; STREPTAVIDIN; TRANSCRIPTOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOINFORMATICS; CAPILLARY ENDOTHELIAL CELL; CELL ISOLATION; CELL JUNCTION; CELL LYSATE; CELL METABOLISM; COMPUTER PROGRAM; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENERGY METABOLISM; HEART MUSCLE CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IRRADIATION; LIQUID CHROMATOGRAPHY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; RADIATION INJURY; SENESCENCE; SERUM; SHAM PROCEDURE; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; TRANSCRIPTOMICS; VASCULAR DISEASE; X RAY; ANIMAL; BLOOD VESSEL; C57BL MOUSE; CYTOLOGY; GENE EXPRESSION PROFILING; PATHOPHYSIOLOGY; RADIATION RESPONSE;

MUS;

ANIMALS; BLOOD VESSELS; CHROMATOGRAPHY, LIQUID; GENE EXPRESSION PROFILING; MICE; MICE, INBRED C57BL; PROTEOMICS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; TRANSCRIPTOME;

EID: 84922636248     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr501141b     Document Type: Article

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