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Volumn 12, Issue 6, 2013, Pages 2700-2714

PPAR alpha: A novel radiation target in locally exposed mus musculus heart revealed by quantitative proteomics

Author keywords

cardiovascular disease; endothelial cell; heart; ICPL; ionizing radiation; PPAR alpha; proteomics

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEOME;

EID: 84879354970     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr400071g     Document Type: Article
Times cited : (54)

References (81)
  • 1
    • 80052015096 scopus 로고    scopus 로고
    • Radiation as a risk factor for cardiovascular disease
    • Baker, J. E.; Moulder, J. E.; Hopewell, J. W. Radiation as a risk factor for cardiovascular disease Antioxid. Redox Signaling 2011, 15 (7) 1945-56
    • (2011) Antioxid. Redox Signaling , vol.15 , Issue.7 , pp. 1945-1956
    • Baker, J.E.1    Moulder, J.E.2    Hopewell, J.W.3
  • 6
    • 0037310039 scopus 로고    scopus 로고
    • Mortality from cardiovascular disease more than 10 years after radiotherapy for breast cancer: Nationwide cohort study of 90 000 Swedish women
    • Darby, S.; McGale, P.; Peto, R.; Granath, F.; Hall, P.; Ekbom, A. Mortality from cardiovascular disease more than 10 years after radiotherapy for breast cancer: nationwide cohort study of 90 000 Swedish women Br. Med. J. 2003, 326 (7383) 256-7
    • (2003) Br. Med. J. , vol.326 , Issue.7383 , pp. 256-257
    • Darby, S.1    McGale, P.2    Peto, R.3    Granath, F.4    Hall, P.5    Ekbom, A.6
  • 7
    • 22944477780 scopus 로고    scopus 로고
    • Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer: Prospective cohort study of about 300,000 women in US SEER cancer registries
    • Darby, S. C.; McGale, P.; Taylor, C. W.; Peto, R. Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer: prospective cohort study of about 300,000 women in US SEER cancer registries Lancet Oncol. 2005, 6 (8) 557-65
    • (2005) Lancet Oncol. , vol.6 , Issue.8 , pp. 557-565
    • Darby, S.C.1    McGale, P.2    Taylor, C.W.3    Peto, R.4
  • 8
    • 0033001044 scopus 로고    scopus 로고
    • Mortality from myocardial infarction following postlumpectomy radiotherapy for breast cancer: A population-based study in Ontario, Canada
    • Paszat, L. F.; Mackillop, W. J.; Groome, P. A.; Schulze, K.; Holowaty, E. Mortality from myocardial infarction following postlumpectomy radiotherapy for breast cancer: a population-based study in Ontario, Canada Int. J. Radiat. Oncol. Biol. Phys. 1999, 43 (4) 755-62
    • (1999) Int. J. Radiat. Oncol. Biol. Phys. , vol.43 , Issue.4 , pp. 755-762
    • Paszat, L.F.1    MacKillop, W.J.2    Groome, P.A.3    Schulze, K.4    Holowaty, E.5
  • 10
    • 61349090453 scopus 로고    scopus 로고
    • Radiation-induced cardiac toxicity after therapy for breast cancer: Interaction between treatment era and follow-up duration
    • Demirci, S.; Nam, J.; Hubbs, J. L.; Nguyen, T.; Marks, L. B. Radiation-induced cardiac toxicity after therapy for breast cancer: interaction between treatment era and follow-up duration Int. J. Radiat. Oncol. Biol. Phys. 2009, 73 (4) 980-7
    • (2009) Int. J. Radiat. Oncol. Biol. Phys. , vol.73 , Issue.4 , pp. 980-987
    • Demirci, S.1    Nam, J.2    Hubbs, J.L.3    Nguyen, T.4    Marks, L.B.5
  • 17
    • 35248852831 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and inflammation: Take it to heart
    • Smeets, P. J.; Planavila, A.; van der Vusse, G. J.; van Bilsen, M. Peroxisome proliferator-activated receptors and inflammation: take it to heart Acta Physiol. 2007, 191 (3) 171-88
    • (2007) Acta Physiol. , vol.191 , Issue.3 , pp. 171-188
    • Smeets, P.J.1    Planavila, A.2    Van Der Vusse, G.J.3    Van Bilsen, M.4
  • 18
    • 67449108376 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-alpha (PPARalpha): At the crossroads of obesity, diabetes and cardiovascular disease
    • Fruchart, J. C. Peroxisome proliferator-activated receptor-alpha (PPARalpha): at the crossroads of obesity, diabetes and cardiovascular disease Atherosclerosis 2009, 205 (1) 1-8
    • (2009) Atherosclerosis , vol.205 , Issue.1 , pp. 1-8
    • Fruchart, J.C.1
  • 19
    • 33845577985 scopus 로고    scopus 로고
    • The PPAR regulatory system in cardiac physiology and disease
    • Finck, B. N. The PPAR regulatory system in cardiac physiology and disease Cardiovasc. Res. 2007, 73 (2) 269-77
    • (2007) Cardiovasc. Res. , vol.73 , Issue.2 , pp. 269-277
    • Finck, B.N.1
  • 21
    • 1042286369 scopus 로고    scopus 로고
    • PPAR alpha activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats
    • Diep, Q. N.; Benkirane, K.; Amiri, F.; Cohn, J. S.; Endemann, D.; Schiffrin, E. L. PPAR alpha activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats J. Mol. Cell. Cardiol. 2004, 36 (2) 295-304
    • (2004) J. Mol. Cell. Cardiol. , vol.36 , Issue.2 , pp. 295-304
    • Diep, Q.N.1    Benkirane, K.2    Amiri, F.3    Cohn, J.S.4    Endemann, D.5    Schiffrin, E.L.6
  • 22
    • 33646252021 scopus 로고    scopus 로고
    • Quantitative analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced proteome alterations in 5L rat hepatoma cells using isotope-coded protein labels
    • Sarioglu, H.; Brandner, S.; Jacobsen, C.; Meindl, T.; Schmidt, A.; Kellermann, J.; Lottspeich, F.; Andrae, U. Quantitative analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced proteome alterations in 5L rat hepatoma cells using isotope-coded protein labels Proteomics 2006, 6 (8) 2407-21
    • (2006) Proteomics , vol.6 , Issue.8 , pp. 2407-2421
    • Sarioglu, H.1    Brandner, S.2    Jacobsen, C.3    Meindl, T.4    Schmidt, A.5    Kellermann, J.6    Lottspeich, F.7    Andrae, U.8
  • 23
    • 0037337310 scopus 로고    scopus 로고
    • A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling
    • Blagoev, B.; Kratchmarova, I.; Ong, S. E.; Nielsen, M.; Foster, L. J.; Mann, M. A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling Nat. Biotechnol. 2003, 21 (3) 315-8
    • (2003) Nat. Biotechnol. , vol.21 , Issue.3 , pp. 315-318
    • Blagoev, B.1    Kratchmarova, I.2    Ong, S.E.3    Nielsen, M.4    Foster, L.J.5    Mann, M.6
  • 25
    • 33747865461 scopus 로고    scopus 로고
    • Applications for protein sequence-function evolution data: MRNA/protein expression analysis and coding SNP scoring tools
    • Thomas, P. D.; Kejariwal, A.; Guo, N.; Mi, H.; Campbell, M. J.; Muruganujan, A.; Lazareva-Ulitsky, B. Applications for protein sequence-function evolution data: mRNA/protein expression analysis and coding SNP scoring tools Nucleic Acids Res. 2006, 34 (Web Server issue) W645-50
    • (2006) Nucleic Acids Res. , vol.34 , Issue.WEB SERVER ISSUE , pp. 645-650
    • Thomas, P.D.1    Kejariwal, A.2    Guo, N.3    Mi, H.4    Campbell, M.J.5    Muruganujan, A.6    Lazareva-Ulitsky, B.7
  • 26
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da, W.; Sherman, B. T.; Lempicki, R. A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources Nat. Protoc. 2009, 4 (1) 44-57
    • (2009) Nat. Protoc. , vol.4 , Issue.1 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 27
    • 36049047977 scopus 로고    scopus 로고
    • Comparative proteomic characterization of articular cartilage tissue from normal donors and patients with osteoarthritis
    • Wu, J.; Liu, W.; Bemis, A.; Wang, E.; Qiu, Y.; Morris, E. A.; Flannery, C. R.; Yang, Z. Comparative proteomic characterization of articular cartilage tissue from normal donors and patients with osteoarthritis Arthritis Rheum. 2007, 56 (11) 3675-84
    • (2007) Arthritis Rheum. , vol.56 , Issue.11 , pp. 3675-3684
    • Wu, J.1    Liu, W.2    Bemis, A.3    Wang, E.4    Qiu, Y.5    Morris, E.A.6    Flannery, C.R.7    Yang, Z.8
  • 28
    • 79851505266 scopus 로고    scopus 로고
    • Reactome knowledgebase of human biological pathways and processes
    • D'Eustachio, P. Reactome knowledgebase of human biological pathways and processes Methods Mol. Biol. 2011, 694, 49-61
    • (2011) Methods Mol. Biol. , vol.694 , pp. 49-61
    • D'Eustachio, P.1
  • 29
    • 0026083903 scopus 로고
    • Tumor angiogenesis and metastasis - Correlation in invasive breast carcinoma
    • Weidner, N.; Semple, J. P.; Welch, W. R.; Folkman, J. Tumor angiogenesis and metastasis - correlation in invasive breast carcinoma N. Engl. J. Med. 1991, 324 (1) 1-8
    • (1991) N. Engl. J. Med. , vol.324 , Issue.1 , pp. 1-8
    • Weidner, N.1    Semple, J.P.2    Welch, W.R.3    Folkman, J.4
  • 30
    • 0033785134 scopus 로고    scopus 로고
    • Immunohistochemical expression of E-selectin in sepsis-induced lung injury
    • Tsokos, M.; Fehlauer, F.; Puschel, K. Immunohistochemical expression of E-selectin in sepsis-induced lung injury Int. J. Legal Med. 2000, 113 (6) 338-42
    • (2000) Int. J. Legal Med. , vol.113 , Issue.6 , pp. 338-342
    • Tsokos, M.1    Fehlauer, F.2    Puschel, K.3
  • 32
    • 84864293013 scopus 로고    scopus 로고
    • Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number
    • Campbell, C. T.; Kolesar, J. E.; Kaufman, B. A. Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number Biochim. Biophys. Acta 2012, 1819 (9-10) 921-9
    • (2012) Biochim. Biophys. Acta , vol.1819 , Issue.910 , pp. 921-929
    • Campbell, C.T.1    Kolesar, J.E.2    Kaufman, B.A.3
  • 33
    • 33644666564 scopus 로고    scopus 로고
    • Plasma free fatty acids and peroxisome proliferator-activated receptor alpha in the control of myocardial uncoupling protein levels
    • Murray, A. J.; Panagia, M.; Hauton, D.; Gibbons, G. F.; Clarke, K. Plasma free fatty acids and peroxisome proliferator-activated receptor alpha in the control of myocardial uncoupling protein levels Diabetes 2005, 54 (12) 3496-502
    • (2005) Diabetes , vol.54 , Issue.12 , pp. 3496-3502
    • Murray, A.J.1    Panagia, M.2    Hauton, D.3    Gibbons, G.F.4    Clarke, K.5
  • 35
    • 33750616552 scopus 로고    scopus 로고
    • Mitochondrial dysfunction, persistently elevated levels of reactive oxygen species and radiation-induced genomic instability: A review
    • Kim, G. J.; Chandrasekaran, K.; Morgan, W. F. Mitochondrial dysfunction, persistently elevated levels of reactive oxygen species and radiation-induced genomic instability: a review Mutagenesis 2006, 21 (6) 361-7
    • (2006) Mutagenesis , vol.21 , Issue.6 , pp. 361-367
    • Kim, G.J.1    Chandrasekaran, K.2    Morgan, W.F.3
  • 36
    • 33750633422 scopus 로고    scopus 로고
    • A role for mitochondrial dysfunction in perpetuating radiation-induced genomic instability
    • Kim, G. J.; Fiskum, G. M.; Morgan, W. F. A role for mitochondrial dysfunction in perpetuating radiation-induced genomic instability Cancer Res. 2006, 66 (21) 10377-83
    • (2006) Cancer Res. , vol.66 , Issue.21 , pp. 10377-10383
    • Kim, G.J.1    Fiskum, G.M.2    Morgan, W.F.3
  • 37
    • 77954987061 scopus 로고    scopus 로고
    • PPARalpha: Energy combustion, hypolipidemia, inflammation and cancer
    • Pyper, S. R.; Viswakarma, N.; Yu, S.; Reddy, J. K. PPARalpha: energy combustion, hypolipidemia, inflammation and cancer Nucl. Recept. Signaling 2010, 8, e002
    • (2010) Nucl. Recept. Signaling , vol.8 , pp. 002
    • Pyper, S.R.1    Viswakarma, N.2    Yu, S.3    Reddy, J.K.4
  • 38
    • 0037417725 scopus 로고    scopus 로고
    • A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content
    • Finck, B. N.; Han, X.; Courtois, M.; Aimond, F.; Nerbonne, J. M.; Kovacs, A.; Gross, R. W.; Kelly, D. P. A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content Proc. Natl. Acad. Sci. U.S.A. 2003, 100 (3) 1226-31
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , Issue.3 , pp. 1226-1231
    • Finck, B.N.1    Han, X.2    Courtois, M.3    Aimond, F.4    Nerbonne, J.M.5    Kovacs, A.6    Gross, R.W.7    Kelly, D.P.8
  • 39
    • 0033933236 scopus 로고    scopus 로고
    • Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth
    • Barger, P. M.; Brandt, J. M.; Leone, T. C.; Weinheimer, C. J.; Kelly, D. P. Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth J. Clin. Invest. 2000, 105 (12) 1723-30
    • (2000) J. Clin. Invest. , vol.105 , Issue.12 , pp. 1723-1730
    • Barger, P.M.1    Brandt, J.M.2    Leone, T.C.3    Weinheimer, C.J.4    Kelly, D.P.5
  • 40
    • 0035920140 scopus 로고    scopus 로고
    • Hypoxia inhibits the peroxisome proliferator-activated receptor alpha/retinoid X receptor gene regulatory pathway in cardiac myocytes: A mechanism for O2-dependent modulation of mitochondrial fatty acid oxidation
    • Huss, J. M.; Levy, F. H.; Kelly, D. P. Hypoxia inhibits the peroxisome proliferator-activated receptor alpha/retinoid X receptor gene regulatory pathway in cardiac myocytes: a mechanism for O2-dependent modulation of mitochondrial fatty acid oxidation J. Biol. Chem. 2001, 276 (29) 27605-12
    • (2001) J. Biol. Chem. , vol.276 , Issue.29 , pp. 27605-27612
    • Huss, J.M.1    Levy, F.H.2    Kelly, D.P.3
  • 41
    • 22544438179 scopus 로고    scopus 로고
    • Downregulation of peroxisome proliferator-activated receptor-alpha gene expression in a mouse model of ischemic cardiomyopathy is dependent on reactive oxygen species and prevents lipotoxicity
    • Dewald, O.; Sharma, S.; Adrogue, J.; Salazar, R.; Duerr, G. D.; Crapo, J. D.; Entman, M. L.; Taegtmeyer, H. Downregulation of peroxisome proliferator-activated receptor-alpha gene expression in a mouse model of ischemic cardiomyopathy is dependent on reactive oxygen species and prevents lipotoxicity Circulation 2005, 112 (3) 407-15
    • (2005) Circulation , vol.112 , Issue.3 , pp. 407-415
    • Dewald, O.1    Sharma, S.2    Adrogue, J.3    Salazar, R.4    Duerr, G.D.5    Crapo, J.D.6    Entman, M.L.7    Taegtmeyer, H.8
  • 42
    • 0035976932 scopus 로고    scopus 로고
    • Reactivation of peroxisome proliferator-activated receptor alpha is associated with contractile dysfunction in hypertrophied rat heart
    • Young, M. E.; Laws, F. A.; Goodwin, G. W.; Taegtmeyer, H. Reactivation of peroxisome proliferator-activated receptor alpha is associated with contractile dysfunction in hypertrophied rat heart J. Biol. Chem. 2001, 276 (48) 44390-5
    • (2001) J. Biol. Chem. , vol.276 , Issue.48 , pp. 44390-44395
    • Young, M.E.1    Laws, F.A.2    Goodwin, G.W.3    Taegtmeyer, H.4
  • 44
    • 0035977050 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase activates peroxisome proliferator-activated receptor alpha: A potential role in the cardiac metabolic stress response
    • Barger, P. M.; Browning, A. C.; Garner, A. N.; Kelly, D. P. p38 mitogen-activated protein kinase activates peroxisome proliferator-activated receptor alpha: a potential role in the cardiac metabolic stress response J. Biol. Chem. 2001, 276 (48) 44495-501
    • (2001) J. Biol. Chem. , vol.276 , Issue.48 , pp. 44495-44501
    • Barger, P.M.1    Browning, A.C.2    Garner, A.N.3    Kelly, D.P.4
  • 45
    • 0037324942 scopus 로고    scopus 로고
    • Myocardial dysfunction and male mortality in peroxisome proliferator-activated receptor alpha knockout mice overexpressing lipoprotein lipase in muscle
    • Nohammer, C.; Brunner, F.; Wolkart, G.; Staber, P. B.; Steyrer, E.; Gonzalez, F. J.; Zechner, R.; Hoefler, G. Myocardial dysfunction and male mortality in peroxisome proliferator-activated receptor alpha knockout mice overexpressing lipoprotein lipase in muscle Lab. Invest. 2003, 83 (2) 259-69
    • (2003) Lab. Invest. , vol.83 , Issue.2 , pp. 259-269
    • Nohammer, C.1    Brunner, F.2    Wolkart, G.3    Staber, P.B.4    Steyrer, E.5    Gonzalez, F.J.6    Zechner, R.7    Hoefler, G.8
  • 46
    • 0030766476 scopus 로고    scopus 로고
    • Alterations in lipoprotein metabolism in peroxisome proliferator- activated receptor alpha-deficient mice
    • Peters, J. M.; Hennuyer, N.; Staels, B.; Fruchart, J. C.; Fievet, C.; Gonzalez, F. J.; Auwerx, J. Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice J. Biol. Chem. 1997, 272 (43) 27307-12
    • (1997) J. Biol. Chem. , vol.272 , Issue.43 , pp. 27307-27312
    • Peters, J.M.1    Hennuyer, N.2    Staels, B.3    Fruchart, J.C.4    Fievet, C.5    Gonzalez, F.J.6    Auwerx, J.7
  • 47
    • 0034747306 scopus 로고    scopus 로고
    • PPARalpha deficiency increases secretion and serum levels of apolipoprotein B-containing lipoproteins
    • Linden, D.; Alsterholm, M.; Wennbo, H.; Oscarsson, J. PPARalpha deficiency increases secretion and serum levels of apolipoprotein B-containing lipoproteins J. Lipid Res. 2001, 42 (11) 1831-40
    • (2001) J. Lipid Res. , vol.42 , Issue.11 , pp. 1831-1840
    • Linden, D.1    Alsterholm, M.2    Wennbo, H.3    Oscarsson, J.4
  • 50
    • 36949006516 scopus 로고    scopus 로고
    • The PPARalpha-PGC-1alpha Axis Controls Cardiac Energy Metabolism in Healthy and Diseased Myocardium
    • Duncan, J. G.; Finck, B. N. The PPARalpha-PGC-1alpha Axis Controls Cardiac Energy Metabolism in Healthy and Diseased Myocardium PPAR Res. 2008, 2008, 253817
    • (2008) PPAR Res. , vol.2008 , pp. 253817
    • Duncan, J.G.1    Finck, B.N.2
  • 51
    • 33745627066 scopus 로고    scopus 로고
    • Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha
    • Arany, Z.; Novikov, M.; Chin, S.; Ma, Y.; Rosenzweig, A.; Spiegelman, B. M. Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha Proc. Natl. Acad. Sci. U.S.A. 2006, 103 (26) 10086-91
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , Issue.26 , pp. 10086-10091
    • Arany, Z.1    Novikov, M.2    Chin, S.3    Ma, Y.4    Rosenzweig, A.5    Spiegelman, B.M.6
  • 52
    • 78349298325 scopus 로고    scopus 로고
    • Gene Expression Profiling in Wild-Type and PPARalpha-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPARalpha-Independent Effects
    • Rosen, M. B.; Schmid, J. R.; Corton, J. C.; Zehr, R. D.; Das, K. P.; Abbott, B. D.; Lau, C. Gene Expression Profiling in Wild-Type and PPARalpha-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPARalpha-Independent Effects PPAR Res. 2010, 2010
    • (2010) PPAR Res. , pp. 2010
    • Rosen, M.B.1    Schmid, J.R.2    Corton, J.C.3    Zehr, R.D.4    Das, K.P.5    Abbott, B.D.6    Lau, C.7
  • 53
    • 33847656213 scopus 로고    scopus 로고
    • Mitochondrial transcription factor A (TFAM): Roles in maintenance of mtDNA and cellular functions
    • Kang, D.; Kim, S. H.; Hamasaki, N. Mitochondrial transcription factor A (TFAM): roles in maintenance of mtDNA and cellular functions Mitochondrion 2007, 7 (1-2) 39-44
    • (2007) Mitochondrion , vol.7 , Issue.12 , pp. 39-44
    • Kang, D.1    Kim, S.H.2    Hamasaki, N.3
  • 57
    • 59449104627 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress and dysfunction in myocardial remodelling
    • Tsutsui, H.; Kinugawa, S.; Matsushima, S. Mitochondrial oxidative stress and dysfunction in myocardial remodelling Cardiovasc. Res. 2009, 81 (3) 449-56
    • (2009) Cardiovasc. Res. , vol.81 , Issue.3 , pp. 449-456
    • Tsutsui, H.1    Kinugawa, S.2    Matsushima, S.3
  • 58
    • 52949153528 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial DNA damage in heart failure
    • Tsutsui, H.; Kinugawa, S.; Matsushima, S. Oxidative stress and mitochondrial DNA damage in heart failure Circ. J. 2008, 72 (Suppl A) A31-7
    • (2008) Circ. J. , vol.72 , Issue.SUPPL. A , pp. 31-37
    • Tsutsui, H.1    Kinugawa, S.2    Matsushima, S.3
  • 59
    • 34248589911 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) regulatory cascade in cardiac physiology and disease
    • Finck, B. N.; Kelly, D. P. Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) regulatory cascade in cardiac physiology and disease Circulation 2007, 115 (19) 2540-8
    • (2007) Circulation , vol.115 , Issue.19 , pp. 2540-2548
    • Finck, B.N.1    Kelly, D.P.2
  • 60
    • 30844433781 scopus 로고    scopus 로고
    • Mitochondrial function, energy expenditure, aging and insulin resistance
    • Ritz, P.; Berrut, G. Mitochondrial function, energy expenditure, aging and insulin resistance Diabetes Metab. 2005, 31 (Spec No 2) 5S67-5S73
    • (2005) Diabetes Metab. , vol.31 , Issue.2
    • Ritz, P.1    Berrut, G.2
  • 61
    • 0034693152 scopus 로고    scopus 로고
    • A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins
    • Koc, E. C.; Burkhart, W.; Blackburn, K.; Moseley, A.; Koc, H.; Spremulli, L. L. A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins J. Biol. Chem. 2000, 275 (42) 32585-91
    • (2000) J. Biol. Chem. , vol.275 , Issue.42 , pp. 32585-32591
    • Koc, E.C.1    Burkhart, W.2    Blackburn, K.3    Moseley, A.4    Koc, H.5    Spremulli, L.L.6
  • 62
    • 62349118232 scopus 로고    scopus 로고
    • Inflammation and chronic oxidative stress in radiation-induced late normal tissue injury: Therapeutic implications
    • Zhao, W.; Robbins, M. E. Inflammation and chronic oxidative stress in radiation-induced late normal tissue injury: therapeutic implications Curr. Med. Chem. 2009, 16 (2) 130-43
    • (2009) Curr. Med. Chem. , vol.16 , Issue.2 , pp. 130-143
    • Zhao, W.1    Robbins, M.E.2
  • 63
    • 10744227975 scopus 로고    scopus 로고
    • Oxidative stress induces nucleo-cytoplasmic translocation of pancreatic transcription factor PDX-1 through activation of c-Jun NH(2)-terminal kinase
    • Kawamori, D.; Kajimoto, Y.; Kaneto, H.; Umayahara, Y.; Fujitani, Y.; Miyatsuka, T.; Watada, H.; Leibiger, I. B.; Yamasaki, Y.; Hori, M. Oxidative stress induces nucleo-cytoplasmic translocation of pancreatic transcription factor PDX-1 through activation of c-Jun NH(2)-terminal kinase Diabetes 2003, 52 (12) 2896-904
    • (2003) Diabetes , vol.52 , Issue.12 , pp. 2896-2904
    • Kawamori, D.1    Kajimoto, Y.2    Kaneto, H.3    Umayahara, Y.4    Fujitani, Y.5    Miyatsuka, T.6    Watada, H.7    Leibiger, I.B.8    Yamasaki, Y.9    Hori, M.10
  • 64
    • 79551575483 scopus 로고    scopus 로고
    • Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo
    • Tan, Y.; Ichikawa, T.; Li, J.; Si, Q.; Yang, H.; Chen, X.; Goldblatt, C. S.; Meyer, C. J.; Li, X.; Cai, L.; Cui, T. Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo Diabetes 2011, 60 (2) 625-33
    • (2011) Diabetes , vol.60 , Issue.2 , pp. 625-633
    • Tan, Y.1    Ichikawa, T.2    Li, J.3    Si, Q.4    Yang, H.5    Chen, X.6    Goldblatt, C.S.7    Meyer, C.J.8    Li, X.9    Cai, L.10    Cui, T.11
  • 66
    • 0037023635 scopus 로고    scopus 로고
    • PPAR activators as antiinflammatory mediators in human T lymphocytes: Implications for atherosclerosis and transplantation-associated arteriosclerosis
    • Marx, N.; Kehrle, B.; Kohlhammer, K.; Grub, M.; Koenig, W.; Hombach, V.; Libby, P.; Plutzky, J. PPAR activators as antiinflammatory mediators in human T lymphocytes: implications for atherosclerosis and transplantation-associated arteriosclerosis Circ. Res. 2002, 90 (6) 703-10
    • (2002) Circ. Res. , vol.90 , Issue.6 , pp. 703-710
    • Marx, N.1    Kehrle, B.2    Kohlhammer, K.3    Grub, M.4    Koenig, W.5    Hombach, V.6    Libby, P.7    Plutzky, J.8
  • 68
    • 84868309553 scopus 로고    scopus 로고
    • Role of PPARs in Radiation-Induced Brain Injury
    • Ramanan, S.; Zhao, W.; Riddle, D. R.; Robbins, M. E. Role of PPARs in Radiation-Induced Brain Injury PPAR Res. 2010, 2010, 234975
    • (2010) PPAR Res. , vol.2010 , pp. 234975
    • Ramanan, S.1    Zhao, W.2    Riddle, D.R.3    Robbins, M.E.4
  • 70
    • 70349925422 scopus 로고    scopus 로고
    • Protective effect of lecithinized SOD on reactive oxygen species-induced xerostomia
    • Tai, Y.; Inoue, H.; Sakurai, T.; Yamada, H.; Morito, M.; Ide, F.; Mishima, K.; Saito, I. Protective effect of lecithinized SOD on reactive oxygen species-induced xerostomia Radiat. Res. 2009, 172 (3) 331-8
    • (2009) Radiat. Res. , vol.172 , Issue.3 , pp. 331-338
    • Tai, Y.1    Inoue, H.2    Sakurai, T.3    Yamada, H.4    Morito, M.5    Ide, F.6    Mishima, K.7    Saito, I.8
  • 71
    • 77956565655 scopus 로고    scopus 로고
    • Mitochondrial aldehyde dehydrogenase and cardiac diseases
    • Chen, C. H.; Sun, L.; Mochly-Rosen, D. Mitochondrial aldehyde dehydrogenase and cardiac diseases Cardiovasc. Res. 2010, 88 (1) 51-7
    • (2010) Cardiovasc. Res. , vol.88 , Issue.1 , pp. 51-57
    • Chen, C.H.1    Sun, L.2    Mochly-Rosen, D.3
  • 73
    • 77955912195 scopus 로고    scopus 로고
    • Altered degradation of extracellular matrix in myocardial remodelling: The growing role of cathepsins and cystatins
    • Diez, J. Altered degradation of extracellular matrix in myocardial remodelling: the growing role of cathepsins and cystatins Cardiovasc. Res. 2010, 87 (4) 591-2
    • (2010) Cardiovasc. Res. , vol.87 , Issue.4 , pp. 591-592
    • Diez, J.1
  • 76
    • 0034813586 scopus 로고    scopus 로고
    • Regulation of beta-amyloid stimulated proinflammatory responses by peroxisome proliferator-activated receptor alpha
    • Combs, C. K.; Bates, P.; Karlo, J. C.; Landreth, G. E. Regulation of beta-amyloid stimulated proinflammatory responses by peroxisome proliferator-activated receptor alpha Neurochem. Int. 2001, 39 (5-6) 449-57
    • (2001) Neurochem. Int. , vol.39 , Issue.56 , pp. 449-457
    • Combs, C.K.1    Bates, P.2    Karlo, J.C.3    Landreth, G.E.4
  • 77
    • 0032706735 scopus 로고    scopus 로고
    • Cellular cofactors for amyloid beta-peptide-induced cell stress. Moving from cell culture to in vivo
    • Yan, S. D.; Roher, A.; Schmidt, A. M.; Stern, D. M. Cellular cofactors for amyloid beta-peptide-induced cell stress. Moving from cell culture to in vivo Am. J. Pathol. 1999, 155 (5) 1403-11
    • (1999) Am. J. Pathol. , vol.155 , Issue.5 , pp. 1403-1411
    • Yan, S.D.1    Roher, A.2    Schmidt, A.M.3    Stern, D.M.4
  • 78
    • 0035854582 scopus 로고    scopus 로고
    • Deposition of Alzheimer's vascular amyloid-beta is associated with decreased expression of brain L-3-hydroxyacyl-coenzyme A dehydrogenase (ERAB)
    • Frackowiak, J.; Mazur-Kolecka, B.; Kaczmarski, W.; Dickson, D. Deposition of Alzheimer's vascular amyloid-beta is associated with decreased expression of brain L-3-hydroxyacyl-coenzyme A dehydrogenase (ERAB) Brain Res. 2001, 907 (1-2) 44-53
    • (2001) Brain Res. , vol.907 , Issue.12 , pp. 44-53
    • Frackowiak, J.1    Mazur-Kolecka, B.2    Kaczmarski, W.3    Dickson, D.4
  • 80
    • 0033934431 scopus 로고    scopus 로고
    • Expression of decorin, biglycan, and collagen type i in human renal fibrosing disease
    • Stokes, M. B.; Holler, S.; Cui, Y.; Hudkins, K. L.; Eitner, F.; Fogo, A.; Alpers, C. E. Expression of decorin, biglycan, and collagen type I in human renal fibrosing disease Kidney Int. 2000, 57 (2) 487-98
    • (2000) Kidney Int. , vol.57 , Issue.2 , pp. 487-498
    • Stokes, M.B.1    Holler, S.2    Cui, Y.3    Hudkins, K.L.4    Eitner, F.5    Fogo, A.6    Alpers, C.E.7
  • 81
    • 81255201265 scopus 로고    scopus 로고
    • Proteomic typing of amyloid deposits in systemic amyloidoses
    • Lavatelli, F.; Vrana, J. A. Proteomic typing of amyloid deposits in systemic amyloidoses Amyloid: Int. J. Exp. Clin. Invest. 2011, 18 (4) 177-82
    • (2011) Amyloid: Int. J. Exp. Clin. Invest. , vol.18 , Issue.4 , pp. 177-182
    • Lavatelli, F.1    Vrana, J.A.2


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