Insulin receptor substrate-1 and phosphoinositide-dependent kinase-1 are required for insulin-stimulated production of nitric oxide in endothelial cells

Molecular Endocrinology

Volumn 16, Issue 8, 2002, Pages 1931-1942

  Montagnani, Monica ^a   Ravichandran, Lingamanaidu V ^a   Chen, Hui ^a   Esposito, Diana L ^b   Quon, Michael J ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b UNIVERSITY OF CHIETI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; 3 PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE; 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1 PROTEIN; INSULIN RECEPTOR SUBSTRATE-1 PROTEIN; NOS3 PROTEIN, HUMAN; NOS3 PROTEIN, MOUSE; NOS3 PROTEIN, RAT; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENE MUTATION; GENE OVEREXPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VASODILATATION; ANIMAL; BIOSYNTHESIS; CATTLE; CELL CULTURE; CYTOLOGY; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MUTATION; PHYSIOLOGY; RAT; VASCULAR ENDOTHELIUM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3 CELLS; ANIMAL; CATTLE; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; HUMAN; INSULIN; MICE; MUTATION; NITRIC OXIDE; NITRIC-OXIDE SYNTHASE; PHOSPHOPROTEINS; PROTEIN-SERINE-THREONINE KINASES; RATS; RECEPTOR, INSULIN; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; TRANSFECTION; VASODILATION; ANIMALS; HUMANS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III;

ANIMALIA;

EID: 0036020513     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2002-0074     Document Type: Article

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