메뉴 건너뛰기




Volumn 89, Issue 3, 2011, Pages 516-524

Insulin says NO to cardiovascular disease

Author keywords

Cardioprotection; Insulin; Insulin resistance; Myocardial ischaemia; Nitric oxide

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CARDIOVASCULAR AGENT; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; GLUCOSE INSULIN POTASSIUM; INSULIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PEROXYNITRITE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; UNCLASSIFIED DRUG;

EID: 79551492488     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvq349     Document Type: Article
Times cited : (135)

References (85)
  • 1
    • 50549176442 scopus 로고
    • Effects of an intravenous infusion of a potassium-glucose-insulin solution on the elec-trocardiographic signs of myocardial infarction. A preliminary clinical report
    • Sodi-Pallares D, Testelli MR, Fishleder BL, Bisteni A, Medrano GA, Friedland C et al. Effects of an intravenous infusion of a potassium-glucose- insulin solution on the elec-trocardiographic signs of myocardial infarction. A preliminary clinical report. Am J Cardiol 1962;9:166-181.
    • (1962) Am J Cardiol , vol.9 , pp. 166-181
    • Sodi-Pallares, D.1    Testelli, M.R.2    Fishleder, B.L.3    Bisteni, A.4    Medrano, G.A.5    Friedland, C.6
  • 2
    • 0001398438 scopus 로고
    • The glucose hypothesis: Relation to acute myocardial ischaemia
    • Opie LH. The glucose hypothesis: relation to acute myocardial ischaemia. J Mol Cell Cardiol 1970;1:107-114.
    • (1970) J Mol Cell Cardiol , vol.1 , pp. 107-114
    • Opie, L.H.1
  • 3
    • 25144473311 scopus 로고    scopus 로고
    • Glucose-insulin-potassium preserves systolic and diastolic function in ischemia and reperfusion in pigs
    • Zhu P, Lu L, Xu Y, Greyson C, Schwartz GG. Glucose-insulin-potassium preserves systolic and diastolic function in ischemia and reperfusion in pigs. Am J Physiol Heart Circ Physiol 2000;278:H595-H603.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278
    • Zhu, P.1    Lu, L.2    Xu, Y.3    Greyson, C.4    Schwartz, G.G.5
  • 4
    • 0035824907 scopus 로고    scopus 로고
    • Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling
    • Jonassen AK, Sack MN, Mjos OD, Yellon DM. Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling. Circ Res 2001;89:1191-1198.
    • (2001) Circ Res , vol.89 , pp. 1191-1198
    • Jonassen, A.K.1    Sack, M.N.2    Mjos, O.D.3    Yellon, D.M.4
  • 5
    • 0037177142 scopus 로고    scopus 로고
    • Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: The roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation
    • Gao F, Gao E, Yue TL, Ohlstein EH, Lopez BL, Christopher TA et al. Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: the roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation. Circulation 2002;105:1497-1502.
    • (2002) Circulation , vol.105 , pp. 1497-1502
    • Gao, F.1    Gao, E.2    Yue, T.L.3    Ohlstein, E.H.4    Lopez, B.L.5    Christopher, T.A.6
  • 6
    • 10044254289 scopus 로고    scopus 로고
    • Insulin signaling in heart muscle: Lessons from genetically engineered mouse models
    • Abel ED. Insulin signaling in heart muscle: lessons from genetically engineered mouse models. Curr Hypertens Rep 2004;6:416-423.
    • (2004) Curr Hypertens Rep , vol.6 , pp. 416-423
    • Abel, E.D.1
  • 8
    • 0141450649 scopus 로고    scopus 로고
    • Insulin: An endogenous cardioprotector
    • Das UN. Insulin: an endogenous cardioprotector. Curr Opin Crit Care 2003;9:375-383.
    • (2003) Curr Opin Crit Care , vol.9 , pp. 375-383
    • Das, U.N.1
  • 9
    • 33644990353 scopus 로고    scopus 로고
    • Forty years of glucose-insulin-potassium (GIK) in cardiac surgery: A review of randomized, controlled trials
    • Schipke JD, Friebe R, Gams E. Forty years of glucose-insulin-potassium (GIK) in cardiac surgery: a review of randomized, controlled trials. Eur J Cardiothorac Surg 2006;29:479-485.
    • (2006) Eur J Cardiothorac Surg , vol.29 , pp. 479-485
    • Schipke, J.D.1    Friebe, R.2    Gams, E.3
  • 10
    • 85047691476 scopus 로고    scopus 로고
    • How does blood glucose control with insulin save lives in intensive care?
    • DOI 10.1172/JCI200423506
    • Van den Berghe G. How does blood glucose control with insulin save lives in intensive care? J Clin Invest 2004;114:1187-1195. (Pubitemid 40385286)
    • (2004) Journal of Clinical Investigation , vol.114 , Issue.9 , pp. 1187-1195
    • Van Den Berghe, G.1
  • 12
    • 0033566864 scopus 로고    scopus 로고
    • Signal transduction of eNOS activation
    • Fleming I, Busse R. Signal transduction of eNOS activation. Cardiovasc Res 1999;43: 532-541.
    • (1999) Cardiovasc Res , vol.43 , pp. 532-541
    • Fleming, I.1    Busse, R.2
  • 13
    • 0036020513 scopus 로고    scopus 로고
    • Insulin receptor substrate-1 and phosphoinositide-dependent kinase-1 are required for insulin-stimulated production of nitric oxide in endothelial cells
    • Montagnani M, Ravichandran LV, Chen H, Esposito DL, Quon MJ. Insulin receptor substrate-1 and phosphoinositide-dependent kinase-1 are required for insulin-stimulated production of nitric oxide in endothelial cells. Mol Endocrinol 2002;16: 1931-1942.
    • (2002) Mol Endocrinol , vol.16 , pp. 1931-1942
    • Montagnani, M.1    Ravichandran, L.V.2    Chen, H.3    Esposito, D.L.4    Quon, M.J.5
  • 14
    • 0034603858 scopus 로고    scopus 로고
    • Roles for insulin receptor, PI3-kinase, and Akt in signaling pathways related to production of nitric oxide in human vascular endothelial cells
    • Zeng G, Nystrom FH, Ravichandran LV, Cong LN, Kirby M, Mostowski H et al. Roles for insulin receptor, PI3-kinase, and Akt in signaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation 2000;98:1539-1545.
    • (2000) Circulation , vol.98 , pp. 1539-1545
    • Zeng, G.1    Nystrom, F.H.2    Ravichandran, L.V.3    Cong, L.N.4    Kirby, M.5    Mostowski, H.6
  • 15
    • 0029789432 scopus 로고    scopus 로고
    • Insulin-stimulated production of nitric oxide is inhibited by wort-mannin. Direct measurement in vascular endothelial cells
    • Zeng G, Quon MJ. Insulin-stimulated production of nitric oxide is inhibited by wort-mannin. Direct measurement in vascular endothelial cells. J Clin Invest 1996;98: 894-898.
    • (1996) J Clin Invest , vol.98 , pp. 894-898
    • Zeng, G.1    Quon, M.J.2
  • 16
    • 34548407280 scopus 로고    scopus 로고
    • Acute hyperglycemia exacerbates myocardial ischemia/reperfusion injury and blunts cardioprotective effect of GIK
    • Su H, Sun X, Ma H, Zhang HF, Yu QJ, Huang C et al. Acute hyperglycemia exacerbates myocardial ischemia/reperfusion injury and blunts cardioprotective effect of GIK. Am J Physiol Endocrinol Metab 2007;293:E629-E635.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • Su, H.1    Sun, X.2    Ma, H.3    Zhang, H.F.4    Yu, Q.J.5    Huang, C.6
  • 17
    • 0033028484 scopus 로고    scopus 로고
    • Myo-cardial ischemia-reperfusion injury is exacerbated in absence of endothelial cell nitric oxide synthase
    • Jones SP, Girod WG, Palazzo AJ, Granger DN, Grisham MB, Jourd'Heuil D et al. Myo-cardial ischemia-reperfusion injury is exacerbated in absence of endothelial cell nitric oxide synthase. Am J Physiol 1999;276:H1567-H1573.
    • (1999) Am J Physiol , vol.276
    • Jones, S.P.1    Girod, W.G.2    Palazzo, A.J.3    Granger, D.N.4    Grisham, M.B.5    Jourd'Heuil, D.6
  • 18
    • 12244266501 scopus 로고    scopus 로고
    • Attenuation of myo-cardial ischemia/reperfusion injury in mice with myocyte-specific overexpression of endothelial nitric oxide synthase
    • Brunner F, Maier R, Andrew P, Wolkart G, Zechner R, Mayer B. Attenuation of myo-cardial ischemia/reperfusion injury in mice with myocyte-specific overexpression of endothelial nitric oxide synthase. Cardiovasc Res 2003;57:55-62.
    • (2003) Cardiovasc Res , vol.57 , pp. 55-62
    • Brunner, F.1    Maier, R.2    Andrew, P.3    Wolkart, G.4    Zechner, R.5    Mayer, B.6
  • 20
    • 0026665948 scopus 로고
    • Beneficial effects of SPM-5185, a cysteine-containing NO donor in myocardial ischemia-reperfusion
    • Siegfried MR, Carey C, Ma XL, Lefer AM. Beneficial effects of SPM-5185, a cysteine-containing NO donor in myocardial ischemia-reperfusion. Am J Physiol 1992;263: H771-H777.
    • (1992) Am J Physiol , vol.263
    • Siegfried, M.R.1    Carey, C.2    Ma, X.L.3    Lefer, A.M.4
  • 21
    • 0035312352 scopus 로고    scopus 로고
    • Treatment of no-reflow and impaired flow with the nitric oxide donor nitroprusside following percutaneous coronary interventions: Initial human clinical experience
    • Hillegass WB, Dean NA, Liao L, Rhinehart RG, Myers PR. Treatment of no-reflow and impaired flow with the nitric oxide donor nitroprusside following percutaneous coronary interventions: initial human clinical experience. J Am Coll Cardiol 2001;37: 1335-1343.
    • (2001) J Am Coll Cardiol , vol.37 , pp. 1335-1343
    • Hillegass, W.B.1    Dean, N.A.2    Liao, L.3    Rhinehart, R.G.4    Myers, P.R.5
  • 22
    • 34547841668 scopus 로고    scopus 로고
    • Nitric oxide inhalation improves microvascular flow and decreases infarction size after myocardial ischemia and reperfusion
    • Liu X, Huang Y, Pokreisz P, Marsboom G, Swinnen M, Verbeken E et al. Nitric oxide inhalation improves microvascular flow and decreases infarction size after myocardial ischemia and reperfusion. J Am Coll Cardiol 2007;50:808-817.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 808-817
    • Liu, X.1    Huang, Y.2    Pokreisz, P.3    Marsboom, G.4    Swinnen, M.5    Verbeken, E.6
  • 23
    • 0034698063 scopus 로고    scopus 로고
    • Endogenous nitric oxide and myo-cardial adaptation to ischemia
    • Heusch G, Post H, Michel MC, Kelm M, Schulz R. Endogenous nitric oxide and myo-cardial adaptation to ischemia. Circ Res 2000;87:146-152.
    • (2000) Circ Res , vol.87 , pp. 146-152
    • Heusch, G.1    Post, H.2    Michel, M.C.3    Kelm, M.4    Schulz, R.5
  • 24
    • 69249232079 scopus 로고    scopus 로고
    • Insulin inhibits leukocyte-endothelium adherence via an Akt-NO-dependent mechanism in myocardial ischemia/reperfusion
    • Li J, Wu F, Zhang H, Fu F, Ji L, Dong L et al. Insulin inhibits leukocyte-endothelium adherence via an Akt-NO-dependent mechanism in myocardial ischemia/reperfusion. J Mol Cell Cardiol 2009;47:512-519.
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 512-519
    • Li, J.1    Wu, F.2    Zhang, H.3    Fu, F.4    Ji, L.5    Dong, L.6
  • 25
    • 1142285456 scopus 로고    scopus 로고
    • Nitric oxide in myocardial ischemia/reperfusion injury
    • Schulz R, Kelm M, Heusch G. Nitric oxide in myocardial ischemia/reperfusion injury. Cardiovasc Res 2004;61:402-413.
    • (2004) Cardiovasc Res , vol.61 , pp. 402-413
    • Schulz, R.1    Kelm, M.2    Heusch, G.3
  • 26
    • 18144387916 scopus 로고    scopus 로고
    • Modulation of apoptosis by nitric oxide: Implications in myocardial ischemia and heart failure
    • Razavi HM, Hamilton JA, Feng Q. Modulation of apoptosis by nitric oxide: implications in myocardial ischemia and heart failure. Pharmacol Ther 2005;106:147-162.
    • (2005) Pharmacol Ther , vol.106 , pp. 147-162
    • Razavi, H.M.1    Hamilton, J.A.2    Feng, Q.3
  • 27
    • 0032971430 scopus 로고    scopus 로고
    • Nitric oxide as a bifunctional regulator of apoptosis
    • Kim YM, Bombeck CA, Billiar TR. Nitric oxide as a bifunctional regulator of apoptosis. Circ Res 1999;84:253-256.
    • (1999) Circ Res , vol.84 , pp. 253-256
    • Kim, Y.M.1    Bombeck, C.A.2    Billiar, T.R.3
  • 28
    • 0032553447 scopus 로고    scopus 로고
    • Nitric oxide suppression of apop-tosis occurs in association with an inhibition of Bcl-2 cleavage and cytochrome c release
    • Kim YM, Kim TH, Seol DW, Talanian RV, Billiar TR. Nitric oxide suppression of apop-tosis occurs in association with an inhibition of Bcl-2 cleavage and cytochrome c release. J Biol Chem 1998;273:31437-31441.
    • (1998) J Biol Chem , vol.273 , pp. 31437-31441
    • Kim, Y.M.1    Kim, T.H.2    Seol, D.W.3    Talanian, R.V.4    Billiar, T.R.5
  • 29
    • 0034682832 scopus 로고    scopus 로고
    • Nitric oxide down-regulates MKP-3 mRNA levels: Involvement in endothelial cell protection from apoptosis
    • Rossig L, Haendeler J, Hermann C, Malchow P, Urbich C, Zeiher AM et al. Nitric oxide down-regulates MKP-3 mRNA levels: involvement in endothelial cell protection from apoptosis. J Biol Chem 2000;275:25502-25507.
    • (2000) J Biol Chem , vol.275 , pp. 25502-25507
    • Rossig, L.1    Haendeler, J.2    Hermann, C.3    Malchow, P.4    Urbich, C.5    Zeiher, A.M.6
  • 30
    • 0035902545 scopus 로고    scopus 로고
    • Apoptosis of endothelial cells precedes myocyte cell apoptosis in ischemia/reperfusion injury
    • Scarabelli T, Stephanou A, Rayment N, Pasini E, Comini L, Curello S et al. Apoptosis of endothelial cells precedes myocyte cell apoptosis in ischemia/reperfusion injury. Circulation 2001;104:253-256.
    • (2001) Circulation , vol.104 , pp. 253-256
    • Scarabelli, T.1    Stephanou, A.2    Rayment, N.3    Pasini, E.4    Comini, L.5    Curello, S.6
  • 31
    • 29144477288 scopus 로고    scopus 로고
    • Vasculoprotective effect of insulin in the ischemic/reperfused canine heart: Role of Akt-stimulated NO production
    • Ma H, Zhang HF, Yu L, Zang QJ, Li J, Huo JH et al. Vasculoprotective effect of insulin in the ischemic/reperfused canine heart: role of Akt-stimulated NO production. Cardiovasc Res 2006;69:57-65.
    • (2006) Cardiovasc Res , vol.69 , pp. 57-65
    • Ma, H.1    Zhang, H.F.2    Yu, L.3    Zang, Q.J.4    Li, J.5    Huo, J.H.6
  • 32
    • 0037162342 scopus 로고    scopus 로고
    • Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells
    • Federici M, Menghini R, Mauriello A, Hribal ML, Ferrelli F, Lauro D et al. Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells. Circulation 2002;106:466-472.
    • (2002) Circulation , vol.106 , pp. 466-472
    • Federici, M.1    Menghini, R.2    Mauriello, A.3    Hribal, M.L.4    Ferrelli, F.5    Lauro, D.6
  • 33
    • 10744232591 scopus 로고    scopus 로고
    • Anti-inflammatory and profibrinolytic effect of insulin in acute ST-segment-elevation myocardial infarction
    • Chaudhuri A, Janicke D, Wilson MF, Tripathy D, Garg R, Bandyopadhyay A et al. Anti-inflammatory and profibrinolytic effect of insulin in acute ST-segment-elevation myocardial infarction. Circulation 2004;109:849-854.
    • (2004) Circulation , vol.109 , pp. 849-854
    • Chaudhuri, A.1    Janicke, D.2    Wilson, M.F.3    Tripathy, D.4    Garg, R.5    Bandyopadhyay, A.6
  • 34
    • 42949103597 scopus 로고    scopus 로고
    • Insulin inhibits tumor necrosis factor-α induction in myocardial ischemia/reperfusion: Role of Akt and endothelial nitric oxide synthase phosphorylation
    • Li J, Zhang H, Wu F, Nan Y, Ma H, Guo W et al. Insulin inhibits tumor necrosis factor-α induction in myocardial ischemia/reperfusion: role of Akt and endothelial nitric oxide synthase phosphorylation. Crit Care Med 2008;36:1551-1558.
    • (2008) Crit Care Med , vol.36 , pp. 1551-1558
    • Li, J.1    Zhang, H.2    Wu, F.3    Nan, Y.4    Ma, H.5    Guo, W.6
  • 35
    • 2642556244 scopus 로고    scopus 로고
    • Endothelial function: A critical determinant in atherosclerosis?
    • Landmesser U, Hornig B, Drexler H. Endothelial function: a critical determinant in atherosclerosis? Circulation 2004;109 (21 Suppl 1):II27-II33.
    • (2004) Circulation , vol.109 , Issue.21 SUPPL. 1
    • Landmesser, U.1    Hornig, B.2    Drexler, H.3
  • 36
    • 0035017056 scopus 로고    scopus 로고
    • Is insulin an antiinflammatory molecule?
    • Das UN. Is insulin an antiinflammatory molecule? Nutrition 2001;17:409-413.
    • (2001) Nutrition , vol.17 , pp. 409-413
    • Das, U.N.1
  • 37
    • 0027396266 scopus 로고
    • Diminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to coronary endothelium
    • Ma XL, Weyrich AS, Lefer DJ, Lefer AM. Diminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to coronary endothelium. Circ Res 1993;72:403-412.
    • (1993) Circ Res , vol.72 , pp. 403-412
    • Ma, X.L.1    Weyrich, A.S.2    Lefer, D.J.3    Lefer, A.M.4
  • 38
    • 0037293568 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning
    • Ferdinandy P, Schulz R. Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning. Br J Pharmacol 2003;138:532-543.
    • (2003) Br J Pharmacol , vol.138 , pp. 532-543
    • Ferdinandy, P.1    Schulz, R.2
  • 39
    • 0031027504 scopus 로고    scopus 로고
    • Peroxynitrite inhibits leukocyte-endothelial cell interactions and protects against ischemia-reperfusion injury in rats
    • Lefer DJ, Scalia R, Campbell B, Nossuli T, Hayward R, Salamon M et al. Peroxynitrite inhibits leukocyte-endothelial cell interactions and protects against ischemia-reperfusion injury in rats. J Clin Invest 1997;99:684-691.
    • (1997) J Clin Invest , vol.99 , pp. 684-691
    • Lefer, D.J.1    Scalia, R.2    Campbell, B.3    Nossuli, T.4    Hayward, R.5    Salamon, M.6
  • 41
    • 32444444967 scopus 로고    scopus 로고
    • Inhibition of iNOS protects the aging heart against b-adrenergic receptor stimulation-induced cardiac dysfunction and myo-cardial ischemic injury
    • Li D, Qu Y, Tao L, Liu H, Hu A, Gao F et al. Inhibition of iNOS protects the aging heart against b-adrenergic receptor stimulation-induced cardiac dysfunction and myo-cardial ischemic injury. J Surg Res 2006;131:64-72.
    • (2006) J Surg Res , vol.131 , pp. 64-72
    • Li, D.1    Qu, Y.2    Tao, L.3    Liu, H.4    Hu, A.5    Gao, F.6
  • 43
    • 0034456622 scopus 로고    scopus 로고
    • Insulin inhibits the expression of intercellular adhesion molecule-1 by human aortic endothelial cells through stimulation of nitric oxide
    • Aljada A, Saadeh R, Assian E, Ghanim H, Dandona P. Insulin inhibits the expression of intercellular adhesion molecule-1 by human aortic endothelial cells through stimulation of nitric oxide. J Clin Endocrinol Metab 2000;85:2572-2575.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2572-2575
    • Aljada, A.1    Saadeh, R.2    Assian, E.3    Ghanim, H.4    Dandona, P.5
  • 44
    • 0034915177 scopus 로고    scopus 로고
    • Insulin inhibits intranuclear nuclear factor kB and stimulates IkB in mononuclear cells in obese subjects: Evidence for an anti-inflammatory effect?
    • Dandona P, Aljada A, Mohanty P, Ghanim H, Hamouda W, Assian E et al. Insulin inhibits intranuclear nuclear factor kB and stimulates IkB in mononuclear cells in obese subjects: evidence for an anti-inflammatory effect? J Clin Endocrinol Metab 2001;86: 3257-3265.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3257-3265
    • Dandona, P.1    Aljada, A.2    Mohanty, P.3    Ghanim, H.4    Hamouda, W.5    Assian, E.6
  • 45
    • 77949783907 scopus 로고    scopus 로고
    • Insulin attenuates myocardial ischemia/ reperfusion injury via reducing oxidative/nitrative stress
    • Ji L, Fu F, Zhang L, Liu W, Cai X, Zhang L et al. Insulin attenuates myocardial ischemia/ reperfusion injury via reducing oxidative/nitrative stress. Am J Physiol Endocrinol Metab 2010;298:E871-E880.
    • (2010) Am J Physiol Endocrinol Metab , vol.298
    • Ji, L.1    Fu, F.2    Zhang, L.3    Liu, W.4    Cai, X.5    Zhang, L.6
  • 47
    • 0033118649 scopus 로고    scopus 로고
    • Contributions of mitochondria to animal physiology: From homeostatic sensor to calcium signalling and cell death
    • Duchen MR. Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death. J Physiol 1999;516:1-17.
    • (1999) J Physiol , vol.516 , pp. 1-17
    • Duchen, M.R.1
  • 48
    • 29244467695 scopus 로고    scopus 로고
    • Signalling via the reperfusion injury signalling kinase (RISK) pathway links closure of the mitochondrial permeability transition pore to cardioprotection
    • Davidson SM, Hausenloy D, Duchen MR, Yellon DM. Signalling via the reperfusion injury signalling kinase (RISK) pathway links closure of the mitochondrial permeability transition pore to cardioprotection. Int J Biochem Cell Biol 2006;38:414-419.
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 414-419
    • Davidson, S.M.1    Hausenloy, D.2    Duchen, M.R.3    Yellon, D.M.4
  • 49
    • 0347579845 scopus 로고    scopus 로고
    • Mitochondrial biogenesis in mammals: The role of endogenous nitric oxide
    • Nisoli E, Clementi E, Paolucci C, Cozzi V, Tonello C, Sciorati C et al. Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide. Science 2003;299: 896-899.
    • (2003) Science , vol.299 , pp. 896-899
    • Nisoli, E.1    Clementi, E.2    Paolucci, C.3    Cozzi, V.4    Tonello, C.5    Sciorati, C.6
  • 50
    • 0032848295 scopus 로고    scopus 로고
    • Biochemical characterization of S-nitrosohemoglobin. Mechanisms underlying synthesis, NO release, and biological activity
    • Wolzt M, MacAllister RJ, Davis D, Feelisch M, Moncada S, Vallance P et al. Biochemical characterization of S-nitrosohemoglobin. Mechanisms underlying synthesis, NO release, and biological activity. J Biol Chem 1999;274:28983- 28990.
    • (1999) J Biol Chem , vol.274 , pp. 28983-28990
    • Wolzt, M.1    MacAllister, R.J.2    Davis, D.3    Feelisch, M.4    Moncada, S.5    Vallance, P.6
  • 51
    • 0032560572 scopus 로고    scopus 로고
    • Persistent inhibition of cell respiration by nitric oxide: Crucial role of S-nitrosylation of mitochondrial complex i and protective action of glutathione
    • Clementi E, Brown GC, Feelisch M, Moncada S. Persistent inhibition of cell respiration by nitric oxide: Crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione. Proc Natl Acad Sci USA 1998;95:7631-7636.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7631-7636
    • Clementi, E.1    Brown, G.C.2    Feelisch, M.3    Moncada, S.4
  • 52
    • 0033573981 scopus 로고    scopus 로고
    • On the mechanism by which vascular endothelial cells regulate their oxygen consumption
    • Clementi E, Brown GC, Foxwell N, Moncada S. On the mechanism by which vascular endothelial cells regulate their oxygen consumption. Proc Natl Acad Sci USA 1999;96: 1559-1562.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 1559-1562
    • Clementi, E.1    Brown, G.C.2    Foxwell, N.3    Moncada, S.4
  • 53
    • 0035146387 scopus 로고    scopus 로고
    • Increased sensitivity of mitochondrial respiration to inhibition by nitric oxide in cardiac hypertrophy
    • Brookes PS, Zhang J, Dai L, Zhou F, Parks DA, Darley-Usmar VM et al. Increased sensitivity of mitochondrial respiration to inhibition by nitric oxide in cardiac hypertrophy. J Mol Cell Cardiol 2001;33:69-82.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 69-82
    • Brookes, P.S.1    Zhang, J.2    Dai, L.3    Zhou, F.4    Parks, D.A.5    Darley-Usmar, V.M.6
  • 54
    • 0033529656 scopus 로고    scopus 로고
    • Perspectives on oxygen sensing
    • Semenza GL. Perspectives on oxygen sensing. Cell 1999;98:281-284.
    • (1999) Cell , vol.98 , pp. 281-284
    • Semenza, G.L.1
  • 55
    • 20044375212 scopus 로고    scopus 로고
    • Myocardial insulin resistance and cardiac complications of diabetes
    • Abel ED. Myocardial insulin resistance and cardiac complications of diabetes. Curr Drug Targets Immune Endocr Metabol Disord 2005;5:219-226.
    • (2005) Curr Drug Targets Immune Endocr Metabol Disord , vol.5 , pp. 219-226
    • Abel, E.D.1
  • 57
    • 33646711638 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia
    • He Z, Opland DM, Way KJ, Ueki K, Bodyak N, Kang PM et al. Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia. Arterioscler Thromb Vasc Biol 2006;26:787-793.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 787-793
    • He, Z.1    Opland, D.M.2    Way, K.J.3    Ueki, K.4    Bodyak, N.5    Kang, P.M.6
  • 58
    • 41149178494 scopus 로고    scopus 로고
    • Hyper-glycemia and acute coronary syndrome: A scientific statement from the American Heart Association Diabetes Committee of the Council on Nutrition, Physical Activity, and Metabolism
    • Deedwania P, Kosiborod M, Barrett E, Ceriello A, Isley W, Mazzone T et al. Hyper-glycemia and acute coronary syndrome: a scientific statement from the American Heart Association Diabetes Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation 2008;117:1610-1619.
    • (2008) Circulation , vol.117 , pp. 1610-1619
    • Deedwania, P.1    Kosiborod, M.2    Barrett, E.3    Ceriello, A.4    Isley, W.5    Mazzone, T.6
  • 59
    • 0022533748 scopus 로고
    • Determinants and importance of stress hyperglycaemia in non-diabetic patients with myocardial infarction
    • Oswald GA, Smith CC, Betteridge DJ, Yudkin JS. Determinants and importance of stress hyperglycaemia in non-diabetic patients with myocardial infarction. Br Med J (Clin Res Ed) 1986;293:917-922.
    • (1986) Br Med J (Clin Res Ed) , vol.293 , pp. 917-922
    • Oswald, G.A.1    Smith, C.C.2    Betteridge, D.J.3    Yudkin, J.S.4
  • 60
    • 0025286817 scopus 로고
    • Elevated circulating levels of tumor necrosis factor in severe chronic heart failure
    • Levine B, Kalman J, Mayer L, Fillit HM, Packer M. Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Engl J Med 1990;323:236-241.
    • (1990) N Engl J Med , vol.323 , pp. 236-241
    • Levine, B.1    Kalman, J.2    Mayer, L.3    Fillit, H.M.4    Packer, M.5
  • 61
    • 33747100569 scopus 로고    scopus 로고
    • Acute insulin resistance in myocardial ischemia: Causes and consequences
    • Smit JWA, Romijn JA. Acute insulin resistance in myocardial ischemia: causes and consequences. Semin Cardiothorac Vasc Anesth 2006;10:215-219.
    • (2006) Semin Cardiothorac Vasc Anesth , vol.10 , pp. 215-219
    • Jwa, S.1    Romijn, J.A.2
  • 62
    • 0035923566 scopus 로고    scopus 로고
    • In vivo myocardial protection from ischemia/reperfusion injury by the peroxisome proliferator-activated receptor-g agonist rosiglitazone
    • Yue Tl, Chen J, Bao W, Narayanan PK, Bril A, Jiang W et al. In vivo myocardial protection from ischemia/reperfusion injury by the peroxisome proliferator-activated receptor-g agonist rosiglitazone. Circulation 2001;104:2588-2594.
    • (2001) Circulation , vol.104 , pp. 2588-2594
    • Tl, Y.1    Chen, J.2    Bao, W.3    Narayanan, P.K.4    Bril, A.5    Jiang, W.6
  • 63
    • 0036314839 scopus 로고    scopus 로고
    • Ligands of the peroxisome proliferator-activated receptors (PPAR-g and PPAR-a) reduce myocardial infarct size
    • Wayman NS, Hattori Y, McDonald MC, Mota-Filipe H, Cuzzocrea S, Pisano B et al. Ligands of the peroxisome proliferator-activated receptors (PPAR-g and PPAR-a) reduce myocardial infarct size. FASEB J 2002;16:1027-1040.
    • (2002) FASEB J , vol.16 , pp. 1027-1040
    • Wayman, N.S.1    Hattori, Y.2    McDonald, M.C.3    Mota-Filipe, H.4    Cuzzocrea, S.5    Pisano, B.6
  • 64
    • 68149137621 scopus 로고    scopus 로고
    • ENOS, metabolic syndrome and cardiovascular disease
    • Huang PL. eNOS, metabolic syndrome and cardiovascular disease. Trends Endocrinol Metab 2009;20:295-302.
    • (2009) Trends Endocrinol Metab , vol.20 , pp. 295-302
    • Huang, P.L.1
  • 66
    • 38649084713 scopus 로고    scopus 로고
    • Insulin inhibits b-adrenergic action in ischemic/reperfused heart: A novel mechanism of insulin in cardioprotection
    • Yu QJ, Si R, Zhou N, Zhang HF, Guo WY, Wang HC et al. Insulin inhibits b-adrenergic action in ischemic/reperfused heart: a novel mechanism of insulin in cardioprotection. Apoptosis 2008;13:305-317.
    • (2008) Apoptosis , vol.13 , pp. 305-317
    • Yu, Q.J.1    Si, R.2    Zhou, N.3    Zhang, H.F.4    Guo, W.Y.5    Wang, H.C.6
  • 67
    • 0033659624 scopus 로고    scopus 로고
    • Insulin resistance in chronic heart failure
    • Coats AJ, Anker S. Insulin resistance in chronic heart failure. J Cardiovasc Pharmacol 2000;35:S9-S14.
    • (2000) J Cardiovasc Pharmacol , vol.35
    • Coats, A.J.1    Anker, S.2
  • 68
    • 1442286779 scopus 로고    scopus 로고
    • Cardiovascular consequences of sleep-disordered breathing: Past, present and future: Report of a workshop from the National Center on Sleep Disorders Research and the National Heart, Lung, and Blood Institute
    • Quan SF, Gersh BJ. Cardiovascular consequences of sleep-disordered breathing: past, present and future: report of a workshop from the National Center on Sleep Disorders Research and the National Heart, Lung, and Blood Institute. Circulation 2004;109:951-957.
    • (2004) Circulation , vol.109 , pp. 951-957
    • Quan, S.F.1    Gersh, B.J.2
  • 71
    • 0842311015 scopus 로고    scopus 로고
    • Evidence for a causal role of the renin-angiotensin system in vascular dysfunction associated with insulin resistance
    • Shinozaki K, Ayajiki K, Nishio Y, Sugaya T, Kashiwagi A, Okamura T. Evidence for a causal role of the renin-angiotensin system in vascular dysfunction associated with insulin resistance. Hypertension 2004;43:255-262.
    • (2004) Hypertension , vol.43 , pp. 255-262
    • Shinozaki, K.1    Ayajiki, K.2    Nishio, Y.3    Sugaya, T.4    Kashiwagi, A.5    Okamura, T.6
  • 72
    • 39849088716 scopus 로고    scopus 로고
    • Reduced cardiotropic response to insulin in spontaneously hypertensive rats: Role of peroxisome proliferator-activated receptor-g-initiated signaling
    • Zhang H, Li J, Li R, Zhang Q, Ma H, Ji Q et al. Reduced cardiotropic response to insulin in spontaneously hypertensive rats: role of peroxisome proliferator-activated receptor-g-initiated signaling. J Hypertens 2008;26:560-569.
    • (2008) J Hypertens , vol.26 , pp. 560-569
    • Zhang, H.1    Li, J.2    Li, R.3    Zhang, Q.4    Ma, H.5    Ji, Q.6
  • 73
    • 0034889199 scopus 로고    scopus 로고
    • Oxidative inac-tivation of nitric oxide and endothelial dysfunction in stroke-prone spontaneous hypertensive rats
    • Ma XL, Gao F, Nelson AH, Lopez BL, Christopher TA, Yue TL et al. Oxidative inac-tivation of nitric oxide and endothelial dysfunction in stroke-prone spontaneous hypertensive rats. J Pharmacol Exp Ther 2001;298:879-885.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 879-885
    • Ma, X.L.1    Gao, F.2    Nelson, A.H.3    Lopez, B.L.4    Christopher, T.A.5    Yue, T.L.6
  • 74
    • 0031934256 scopus 로고    scopus 로고
    • Metabolic disturbances in diabetic cardiomyopa-thy
    • Rodrigues B, Cam MC, McNeill JH. Metabolic disturbances in diabetic cardiomyopa-thy. Mol Cell Biochem 1998;180:53-57.
    • (1998) Mol Cell Biochem , vol.180 , pp. 53-57
    • Rodrigues, B.1    Cam, M.C.2    McNeill, J.H.3
  • 75
    • 34250758172 scopus 로고    scopus 로고
    • Swim training sensitizes myocardial response to insulin: Role of Akt-dependent eNOS activation
    • Zhang QJ, Li QX, Zhang HF, Zhang KR, Guo WY, Wang HC et al. Swim training sensitizes myocardial response to insulin: role of Akt-dependent eNOS activation. Cardiovasc Res 2007;75:369-380.
    • (2007) Cardiovasc Res , vol.75 , pp. 369-380
    • Zhang, Q.J.1    Li, Q.X.2    Zhang, H.F.3    Zhang, K.R.4    Guo, W.Y.5    Wang, H.C.6
  • 76
    • 64949129597 scopus 로고    scopus 로고
    • Aging-associated insulin resistance predisposes to hypertension and its reversal by exercise: The role of vascular vasorelaxation to insulin
    • Li QX, Xiong ZY, Hu BP, Tian ZJ, Zhang HF, Guo WY et al. Aging-associated insulin resistance predisposes to hypertension and its reversal by exercise: the role of vascular vasorelaxation to insulin. Basic Res Cardiol 2009;104:269-284.
    • (2009) Basic Res Cardiol , vol.104 , pp. 269-284
    • Li, Q.X.1    Xiong, Z.Y.2    Hu, B.P.3    Tian, Z.J.4    Zhang, H.F.5    Guo, W.Y.6
  • 77
    • 0038755650 scopus 로고    scopus 로고
    • Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase
    • Hambrecht R, Adams V, Erbs S, Linke A, Kränkel N, Shu Y et al. Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase. Circulation 2003; 107:3152-3158.
    • (2003) Circulation , vol.107 , pp. 3152-3158
    • Hambrecht, R.1    Adams, V.2    Erbs, S.3    Linke, A.4    Kränkel, N.5    Shu, Y.6
  • 78
    • 67650242010 scopus 로고    scopus 로고
    • Myocardial protection by nitrite
    • Calvert JW, Lefer DJ. Myocardial protection by nitrite. Cardiovasc Res 2009;83: 195-203.
    • (2009) Cardiovasc Res , vol.83 , pp. 195-203
    • Calvert, J.W.1    Lefer, D.J.2
  • 79
    • 79551473199 scopus 로고    scopus 로고
    • Cardioprotective effects of nitrite during exercise
    • Calvert JW. Cardioprotective effects of nitrite during exercise. Cardiovasc Res 2011; 89:499-506.
    • (2011) Cardiovasc Res , vol.89 , pp. 499-506
    • Calvert, J.W.1
  • 80
    • 34547121683 scopus 로고    scopus 로고
    • Long-term aerobic exercise protects the heart against ischemia/reperfusion injury via PI3 kinase-dependent and Akt-mediated mechanism
    • Zhang KR, Liu HT, Zhang HF, Zhang QJ, Li QX, Yu QJ et al. Long-term aerobic exercise protects the heart against ischemia/reperfusion injury via PI3 kinase-dependent and Akt-mediated mechanism. Apoptosis 2007;12:1579-1588.
    • (2007) Apoptosis , vol.12 , pp. 1579-1588
    • Zhang, K.R.1    Liu, H.T.2    Zhang, H.F.3    Zhang, Q.J.4    Li, Q.X.5    Yu, Q.J.6
  • 81
    • 19644384530 scopus 로고    scopus 로고
    • Glucose-insulin-potassium infusion and mortality in the CREATE-ECLA trial
    • Apstein CS. Glucose-insulin-potassium infusion and mortality in the CREATE-ECLA trial. JAMA 2005;293:2596-2597.
    • (2005) JAMA , vol.293 , pp. 2596-2597
    • Apstein, C.S.1
  • 82
    • 17144378559 scopus 로고    scopus 로고
    • Insulin vs. strict blood glucose control to achieve a survival benefit after AMI?
    • Van den Berghe G. Insulin vs. strict blood glucose control to achieve a survival benefit after AMI? Eur Heart J 2005;26:639-641.
    • (2005) Eur Heart J , vol.26 , pp. 639-641
    • Van Den Berghe, G.1
  • 83
    • 73349129356 scopus 로고    scopus 로고
    • Differential clinical outcomes associated with hypoglycemia and hyperglycemia in acute myocardial infarction
    • Goyal A, Mehta SR, D́az R, Gerstein HC, Afzal R, Xavier D et al. Differential clinical outcomes associated with hypoglycemia and hyperglycemia in acute myocardial infarction. Circulation 2009;120:2429-2437.
    • (2009) Circulation , vol.120 , pp. 2429-2437
    • Goyal, A.1    Mehta, S.R.2    D́az, R.3    Gerstein, H.C.4    Afzal, R.5    Xavier, D.6
  • 84
    • 0036164426 scopus 로고    scopus 로고
    • P38 MAPK inhibition reduces myocardial reperfusion injury via inhibition of endothelial adhesion molecule expression and blockade of PMN accumulation
    • Gao F, Yue TL, Shi DW, Christopher TA, Lopez BL, Ohlstein EH et al. P38 MAPK inhibition reduces myocardial reperfusion injury via inhibition of endothelial adhesion molecule expression and blockade of PMN accumulation. Cardiovasc Res 2002;53: 414-422.
    • (2002) Cardiovasc Res , vol.53 , pp. 414-422
    • Gao, F.1    Yue, T.L.2    Shi, D.W.3    Christopher, T.A.4    Lopez, B.L.5    Ohlstein, E.H.6
  • 85
    • 65549171108 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase: A critical node linking insulin resistance and cardiovascular diseases in type 2 diabetes mellitus
    • Liu Z, Cao W. P38 mitogen-activated protein kinase: a critical node linking insulin resistance and cardiovascular diseases in type 2 diabetes mellitus. Endocr Metab Immune Disord Drug Targets 2009;9:38-46.
    • (2009) Endocr Metab Immune Disord Drug Targets , vol.9 , pp. 38-46
    • Liu, Z.1    Cao, W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.