Inhibition of IGF-1R Prevents Ionizing Radiation-Induced Primary Endothelial Cell Senescence

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Panganiban, Ronald Allan M ^a   Day, Regina M ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 3 BROMO 5 TERT BUTYL 4 HYDROXYBENZYLIDENEMALONONITRILE; BETA GALACTOSIDASE; CELL MARKER; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P21; PROTEIN P53; RAPAMYCIN; SENESCENCE ASSOCIATED BETA GALACTOSIDASE; SOMATOMEDIN B; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IONIZING RADIATION; PRIMARY CELL CULTURE; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN MICROARRAY; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PULMONARY ARTERY; QUANTITATIVE ANALYSIS; RADIATION DOSE; RADIATION EXPOSURE; REAL TIME POLYMERASE CHAIN REACTION; SENESCENCE; SIGNAL TRANSDUCTION; UPREGULATION; X RAY;

CELL AGING; ENDOTHELIAL CELLS; HUMANS; LUNG; PHENOTYPE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; TIME FACTORS; TOR SERINE-THREONINE KINASES; TYRPHOSTINS; X-RAYS;

EID: 84886258224     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078589     Document Type: Article

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