Local heart irradiation of ApoE-/- mice induces microvascular and endocardial damage and accelerates coronary atherosclerosis

Radiotherapy and Oncology

Volumn 105, Issue 3, 2012, Pages 358-364

  Gabriels, Karen ^a   Hoving, Saske ^b   Seemann, Ingar ^b   Visser, Nils L ^b   Gijbels, Marion J ^a,c   Pol, Jeffrey F ^a   Daemen, Mat J ^a,d   Stewart, Fiona A ^b   Heeneman, Sylvia ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c Cardiovascular Research Institute Maastricht ^*  (Netherlands)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Apolipoprotein E; Coronary lesions; Endocardial damage; Irradiation; Microvascular damage

Indexed keywords

ALKALINE PHOSPHATASE; APOLIPOPROTEIN E; VON WILLEBRAND FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; DISEASE COURSE; ECHOGRAPHY; ENDOCARDIAL DISEASE; ENDOCARDIUM; ENZYME ACTIVITY; FIBROSIS; FOAM CELL; FOLLOW UP; GATED SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; HEART FUNCTION; HEART INJURY; HEART MUSCLE; HISTOPATHOLOGY; HYPERCHOLESTEROLEMIA; INFLAMMATORY CELL; MALE; MICROANGIOPATHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION DOSE; RADIATION INJURY;

ANIMALS; APOLIPOPROTEINS E; CORONARY ARTERY DISEASE; DOSE-RESPONSE RELATIONSHIP, RADIATION; ENDOCARDIUM; HEART; MICE; MICE, KNOCKOUT; RADIATION DOSAGE; RADIATION INJURIES, EXPERIMENTAL; TIME FACTORS;

EID: 84871186267     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2012.08.002     Document Type: Article

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