Identification of small molecule inhibitors of phosphatidylinositol 3-kinase and autophagy

Journal of Biological Chemistry

Volumn 286, Issue 45, 2011, Pages 38904-38912

  Farkas, Thomas ^a   Daugaard, Mads ^a,b   Jäättelä, Marja ^a  

^a DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIA-TELANGIECTASIA MUTATED; AUTOPHAGOSOMES; AUTOPHAGY; CATABOLIC PATHWAY; CELL SURVIVAL; CELLULAR HOMEOSTASIS; CLASS I; DEGENERATIVE DISEASE; EXPERIMENTAL STUDIES; INHIBITORY EFFECT; JANUS KINASE; KINASE TARGETS; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHOINOSITIDES; POTENT INHIBITOR; PROTEIN KINASE C; SMALL MOLECULE INHIBITOR; SMALL MOLECULES;

AMINO ACIDS; CELL DEATH; DISEASES; MOLECULES;

ENZYMES;

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 MORPHOLINO 6 (1 THIANTHRENYL) 4 PYRANONE; 3 METHYLADENINE; ATM PROTEIN; JANUS KINASE 3; JANUS KINASE 3 INHIBITOR; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN KINASE C; RAPAMYCIN; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG SCREENING; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

AUTOPHAGY; CARBAZOLES; CELL LINE, TUMOR; ENZYME INHIBITORS; FEMALE; HUMANS; MORPHOLINES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PYRONES; SIGNAL TRANSDUCTION;

ATAXIA TELANGIECTASIA;

EID: 80655144753     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.269134     Document Type: Article

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