Heterozygous Ambra1 deficiency in mice: A genetic trait with autism-like behavior restricted to the female gender

Frontiers in Behavioral Neuroscience

Volumn 8, Issue MAY, 2014, Pages

  Dere, Ekrem ^a,b   Dahm, Liane ^a   Lu, Derek ^a   Hammerschmidt, Kurt ^c   Ju, Anes ^a   Tantra, Martesa ^a   Kästner, Anne ^a   Chowdhury, Kamal ^d   Ehrenreich, Hannelore ^a,b  

^a MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^b Deutsche Forschungsgemeinschaft   (Germany)

^c GERMAN PRIMATE CENTER   (Germany)

^d MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

Ambra1; Autism composite score; Autophagy; Cognitive rigidity; Heterozygous null mutant mice; Repetitive behavior; Social interaction; Ultrasound communication

Indexed keywords

AMBRA1 PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; AMBRA1 GENE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTISM; CIRCLING BEHAVIOR; COMPULSION; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENETIC TRAIT; HETEROZYGOTE; LOSS OF FUNCTION MUTATION; MALE; MAZE TEST; MOUSE; NEWBORN; NONHUMAN; PHENOTYPE; SCORING SYSTEM; SEX DIFFERENCE; SOCIAL DISABILITY; SOCIAL INTERACTION; STEREOTYPY; VOCALIZATION;

EID: 84901380438     PISSN: 16625153     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnbeh.2014.00181     Document Type: Article

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