-
1
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee R.C., Feinbaum R.L., Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993, 75:843-854.
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
2
-
-
0034708122
-
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
-
Reinhart B.J., Slack F.J., Basson M., Pasquinelli A.E., Bettinger J.C., Rougvie A.E., Horvitz H.R., Ruvkun G. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 2000, 403:901-906.
-
(2000)
Nature
, vol.403
, pp. 901-906
-
-
Reinhart, B.J.1
Slack, F.J.2
Basson, M.3
Pasquinelli, A.E.4
Bettinger, J.C.5
Rougvie, A.E.6
Horvitz, H.R.7
Ruvkun, G.8
-
3
-
-
0038343499
-
MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing
-
Ambros V. MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing. Cell 2003, 113:673-676.
-
(2003)
Cell
, vol.113
, pp. 673-676
-
-
Ambros, V.1
-
4
-
-
0344232733
-
MicroRNAs: runts of the genome assert themselves
-
Lai E.C. microRNAs: runts of the genome assert themselves. Curr. Biol. 2003, 13:R925-R936.
-
(2003)
Curr. Biol.
, vol.13
, pp. R925-R936
-
-
Lai, E.C.1
-
5
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
6
-
-
0037273432
-
Sequence requirements for micro RNA processing and function in human cells
-
Zeng Y., Cullen B.R. Sequence requirements for micro RNA processing and function in human cells. RNA 2003, 9:112-123.
-
(2003)
RNA
, vol.9
, pp. 112-123
-
-
Zeng, Y.1
Cullen, B.R.2
-
7
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y., Ahn C., Han J., Choi H., Kim J., Yim J., Lee J., Provost P., Radmark O., Kim S., Kim V.N. The nuclear RNase III Drosha initiates microRNA processing. Nature 2003, 425:415-419.
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Radmark, O.9
Kim, S.10
Kim, V.N.11
-
8
-
-
9144225636
-
The microprocessor complex mediates the genesis of microRNAs
-
Gregory R.I., Yan K.P., Amuthan G., Chendrimada T., Doratotaj B., Cooch N., Shiekhattar R. The microprocessor complex mediates the genesis of microRNAs. Nature 2004, 432:235-240.
-
(2004)
Nature
, vol.432
, pp. 235-240
-
-
Gregory, R.I.1
Yan, K.P.2
Amuthan, G.3
Chendrimada, T.4
Doratotaj, B.5
Cooch, N.6
Shiekhattar, R.7
-
9
-
-
10644234841
-
The Drosha-DGCR8 complex in primary microRNA processing
-
Han J., Lee Y., Yeom K.H., Kim Y.K., Jin H., Kim V.N. The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev. 2004, 18:3016-3027.
-
(2004)
Genes Dev.
, vol.18
, pp. 3016-3027
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
Kim, Y.K.4
Jin, H.5
Kim, V.N.6
-
10
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi R., Qin Y., Macara I.G., Cullen B.R. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 2003, 17:3011-3016.
-
(2003)
Genes Dev.
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
Macara, I.G.3
Cullen, B.R.4
-
11
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund E., Guttinger S., Calado A., Dahlberg J.E., Kutay U. Nuclear export of microRNA precursors. Science 2004, 303:95-98.
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
12
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
Hutvagner G., McLachlan J., Pasquinelli A.E., Balint E., Tuschl T., Zamore P.D. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 2001, 293:834-838.
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvagner, G.1
McLachlan, J.2
Pasquinelli, A.E.3
Balint, E.4
Tuschl, T.5
Zamore, P.D.6
-
13
-
-
3042767202
-
MicroRNAs: small RNAs with a big role in gene regulation
-
He L., Hannon G.J. MicroRNAs: small RNAs with a big role in gene regulation. Nat. Rev. Genet. 2004, 5:522-531.
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
14
-
-
33645294070
-
Oncomirs - microRNAs with a role in cancer
-
Esquela-Kerscher A., Slack F.J. Oncomirs - microRNAs with a role in cancer. Nat. Rev. Cancer 2006, 6:259-269.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 259-269
-
-
Esquela-Kerscher, A.1
Slack, F.J.2
-
16
-
-
58649107855
-
MicroRNA and cancer-focus on apoptosis
-
Wang Y., Lee C.G. MicroRNA and cancer-focus on apoptosis. J. Cell. Mol. Med. 2009, 13:12-23.
-
(2009)
J. Cell. Mol. Med.
, vol.13
, pp. 12-23
-
-
Wang, Y.1
Lee, C.G.2
-
17
-
-
80052041185
-
MicroRNA regulation by RNA-binding proteins and its implications for cancer
-
van Kouwenhove M., Kedde M., Agami R. MicroRNA regulation by RNA-binding proteins and its implications for cancer. Nat. Rev. Cancer 2011, 11:644-656.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 644-656
-
-
van Kouwenhove, M.1
Kedde, M.2
Agami, R.3
-
18
-
-
34547807676
-
MiRNAs in cancer: approaches, aetiology, diagnostics and therapy
-
Blenkiron C., Miska E.A. miRNAs in cancer: approaches, aetiology, diagnostics and therapy. Hum. Mol. Genet. 2007, 16(Spec No 1):R106-R113.
-
(2007)
Hum. Mol. Genet.
, vol.16
, Issue.1
, pp. R106-R113
-
-
Blenkiron, C.1
Miska, E.A.2
-
19
-
-
83255192141
-
Developing therapeutic microRNAs for cancer
-
Bader A.G., Brown D., Stoudemire J., Lammers P. Developing therapeutic microRNAs for cancer. Gene Ther. 2011, 18:1121-1126.
-
(2011)
Gene Ther.
, vol.18
, pp. 1121-1126
-
-
Bader, A.G.1
Brown, D.2
Stoudemire, J.3
Lammers, P.4
-
20
-
-
84885860212
-
MicroRNA and epigenetics: diagnostic and therapeutic opportunities
-
Monroig P.D., Calin G.A. MicroRNA and epigenetics: diagnostic and therapeutic opportunities. Curr. Pathobiol. Rep. 2013, 1:43-52.
-
(2013)
Curr. Pathobiol. Rep.
, vol.1
, pp. 43-52
-
-
Monroig, P.D.1
Calin, G.A.2
-
21
-
-
77952041735
-
Non-coding RNAs: identification of cancer-associated microRNAs by gene profiling
-
Ferdin J., Kunej T., Calin G.A. Non-coding RNAs: identification of cancer-associated microRNAs by gene profiling. Technol. Cancer Res. Treat. 2010, 9:123-138.
-
(2010)
Technol. Cancer Res. Treat.
, vol.9
, pp. 123-138
-
-
Ferdin, J.1
Kunej, T.2
Calin, G.A.3
-
22
-
-
79956190689
-
MicroRNA profiling in cancer
-
Munker R., Calin G.A. MicroRNA profiling in cancer. Clin. Sci. (Lond.) 2011, 121:141-158.
-
(2011)
Clin. Sci. (Lond.)
, vol.121
, pp. 141-158
-
-
Munker, R.1
Calin, G.A.2
-
23
-
-
84887160644
-
The role of microRNAs in the tumorigenesis of ovarian cancer
-
Di Leva G., Croce C.M. The role of microRNAs in the tumorigenesis of ovarian cancer. Front. Oncol. 2013, 3:153.
-
(2013)
Front. Oncol.
, vol.3
, pp. 153
-
-
Di Leva, G.1
Croce, C.M.2
-
24
-
-
78649919224
-
MicroRNA-21 promotes the cell proliferation, invasion and migration abilities in ovarian epithelial carcinomas through inhibiting the expression of PTEN protein
-
Lou Y., Yang X., Wang F., Cui Z., Huang Y. MicroRNA-21 promotes the cell proliferation, invasion and migration abilities in ovarian epithelial carcinomas through inhibiting the expression of PTEN protein. Int. J. Mol. Med. 2010, 26:819-827.
-
(2010)
Int. J. Mol. Med.
, vol.26
, pp. 819-827
-
-
Lou, Y.1
Yang, X.2
Wang, F.3
Cui, Z.4
Huang, Y.5
-
25
-
-
55549120234
-
MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis
-
Yan L.X., Huang X.F., Shao Q., Huang M.Y., Deng L., Wu Q.L., Zeng Y.X., Shao J.Y. MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis. RNA 2008, 14:2348-2360.
-
(2008)
RNA
, vol.14
, pp. 2348-2360
-
-
Yan, L.X.1
Huang, X.F.2
Shao, Q.3
Huang, M.Y.4
Deng, L.5
Wu, Q.L.6
Zeng, Y.X.7
Shao, J.Y.8
-
26
-
-
54749089002
-
Small-molecule inhibitors of microrna miR-21 function
-
Gumireddy K., Young D.D., Xiong X., Hogenesch J.B., Huang Q., Deiters A. Small-molecule inhibitors of microrna miR-21 function. Angew. Chem. Int. Ed. Engl. 2008, 47:7482-7484.
-
(2008)
Angew. Chem. Int. Ed. Engl.
, vol.47
, pp. 7482-7484
-
-
Gumireddy, K.1
Young, D.D.2
Xiong, X.3
Hogenesch, J.B.4
Huang, Q.5
Deiters, A.6
-
27
-
-
84877060316
-
Targeting miR-21 for the therapy of pancreatic cancer
-
Sicard F., Gayral M., Lulka H., Buscail L., Cordelier P. Targeting miR-21 for the therapy of pancreatic cancer. Mol. Ther. 2013, 21:986-994.
-
(2013)
Mol. Ther.
, vol.21
, pp. 986-994
-
-
Sicard, F.1
Gayral, M.2
Lulka, H.3
Buscail, L.4
Cordelier, P.5
-
28
-
-
33144490646
-
A microRNA expression signature of human solid tumors defines cancer gene targets
-
Volinia S., Calin G.A., Liu C.G., Ambs S., Cimmino A., Petrocca F., Visone R., Iorio M., Roldo C., Ferracin M., Prueitt R.L., Yanaihara N., Lanza G., Scarpa A., Vecchione A., Negrini M., Harris C.C., Croce C.M. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:2257-2261.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 2257-2261
-
-
Volinia, S.1
Calin, G.A.2
Liu, C.G.3
Ambs, S.4
Cimmino, A.5
Petrocca, F.6
Visone, R.7
Iorio, M.8
Roldo, C.9
Ferracin, M.10
Prueitt, R.L.11
Yanaihara, N.12
Lanza, G.13
Scarpa, A.14
Vecchione, A.15
Negrini, M.16
Harris, C.C.17
Croce, C.M.18
-
29
-
-
84893745579
-
MiR-155 at the heart of oncogenic pathways
-
Czyzyk-Krzeska M.F., Zhang X. MiR-155 at the heart of oncogenic pathways. Oncogene 2014, 33:677-678.
-
(2014)
Oncogene
, vol.33
, pp. 677-678
-
-
Czyzyk-Krzeska, M.F.1
Zhang, X.2
-
30
-
-
84888117735
-
MiRNA and mRNA cancer signatures determined by analysis of expression levels in large cohorts of patients
-
Zadran S., Remacle F., Levine R.D. miRNA and mRNA cancer signatures determined by analysis of expression levels in large cohorts of patients. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:19160-19165.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 19160-19165
-
-
Zadran, S.1
Remacle, F.2
Levine, R.D.3
-
31
-
-
84902254501
-
Evaluation of microRNA-10b prognostic significance in a prospective cohort of breast cancer patients
-
Parrella P., Barbano R., Pasculli B., Fontana A., Copetti M., Valori V.M., Poeta M.L., Perrone G., Righi D., Castelvetere M., Coco M., Balsamo T., Morritti M., Pellegrini F., Onetti-Muda A., Maiello E., Murgo R., Fazio V.M. Evaluation of microRNA-10b prognostic significance in a prospective cohort of breast cancer patients. Mol. Cancer 2014, 13:142.
-
(2014)
Mol. Cancer
, vol.13
, pp. 142
-
-
Parrella, P.1
Barbano, R.2
Pasculli, B.3
Fontana, A.4
Copetti, M.5
Valori, V.M.6
Poeta, M.L.7
Perrone, G.8
Righi, D.9
Castelvetere, M.10
Coco, M.11
Balsamo, T.12
Morritti, M.13
Pellegrini, F.14
Onetti-Muda, A.15
Maiello, E.16
Murgo, R.17
Fazio, V.M.18
-
32
-
-
77957361864
-
Targeting microRNAs in cancer: rationale, strategies and challenges
-
Garzon R., Marcucci G., Croce C.M. Targeting microRNAs in cancer: rationale, strategies and challenges. Nat. Rev. Drug Discov. 2010, 9:775-789.
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 775-789
-
-
Garzon, R.1
Marcucci, G.2
Croce, C.M.3
-
33
-
-
78650624101
-
RNA interference in the clinic: challenges and future directions
-
Pecot C.V., Calin G.A., Coleman R.L., Lopez-Berestein G., Sood A.K. RNA interference in the clinic: challenges and future directions. Nat. Rev. Cancer 2011, 11:59-67.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 59-67
-
-
Pecot, C.V.1
Calin, G.A.2
Coleman, R.L.3
Lopez-Berestein, G.4
Sood, A.K.5
-
34
-
-
3142781225
-
Small-molecule inhibitors of protein-protein interactions: progressing towards the dream
-
Arkin M.R., Wells J.A. Small-molecule inhibitors of protein-protein interactions: progressing towards the dream. Nat. Rev. Drug Discov. 2004, 3:301-317.
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 301-317
-
-
Arkin, M.R.1
Wells, J.A.2
-
35
-
-
57749188299
-
Targeting cancer with small molecule kinase inhibitors
-
Zhang J., Yang P.L., Gray N.S. Targeting cancer with small molecule kinase inhibitors. Nat. Rev. Cancer 2009, 9:28-39.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 28-39
-
-
Zhang, J.1
Yang, P.L.2
Gray, N.S.3
-
36
-
-
77952584924
-
Targeting microRNAs with small molecules: from dream to reality
-
Zhang S., Chen L., Jung E.J., Calin G.A. Targeting microRNAs with small molecules: from dream to reality. Clin. Pharmacol. Ther. 2010, 87:754-758.
-
(2010)
Clin. Pharmacol. Ther.
, vol.87
, pp. 754-758
-
-
Zhang, S.1
Chen, L.2
Jung, E.J.3
Calin, G.A.4
-
37
-
-
77950665077
-
Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model
-
Ma L., Reinhardt F., Pan E., Soutschek J., Bhat B., Marcusson E.G., Teruya-Feldstein J., Bell G.W., Weinberg R.A. Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model. Nat. Biotechnol. 2010, 28:341-347.
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 341-347
-
-
Ma, L.1
Reinhardt, F.2
Pan, E.3
Soutschek, J.4
Bhat, B.5
Marcusson, E.G.6
Teruya-Feldstein, J.7
Bell, G.W.8
Weinberg, R.A.9
-
38
-
-
84887140184
-
Silencing of the miR-17~92 cluster family inhibits medulloblastoma progression
-
Murphy B.L., Obad S., Bihannic L., Ayrault O., Zindy F., Kauppinen S., Roussel M.F. Silencing of the miR-17~92 cluster family inhibits medulloblastoma progression. Cancer Res. 2013, 73:7068-7078.
-
(2013)
Cancer Res.
, vol.73
, pp. 7068-7078
-
-
Murphy, B.L.1
Obad, S.2
Bihannic, L.3
Ayrault, O.4
Zindy, F.5
Kauppinen, S.6
Roussel, M.F.7
-
39
-
-
84869120708
-
Discovering the first microRNA-targeted drug
-
Lindow M., Kauppinen S. Discovering the first microRNA-targeted drug. J. Cell Biol. 2012, 199:407-412.
-
(2012)
J. Cell Biol.
, vol.199
, pp. 407-412
-
-
Lindow, M.1
Kauppinen, S.2
-
40
-
-
84877258007
-
Treatment of HCV infection by targeting microRNA
-
Janssen H.L., Reesink H.W., Lawitz E.J., Zeuzem S., Rodriguez-Torres M., Patel K., van der Meer A.J., Patick A.K., Chen A., Zhou Y., Persson R., King B.D., Kauppinen S., Levin A.A., Hodges M.R. Treatment of HCV infection by targeting microRNA. N. Engl. J. Med. 2013, 368:1685-1694.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 1685-1694
-
-
Janssen, H.L.1
Reesink, H.W.2
Lawitz, E.J.3
Zeuzem, S.4
Rodriguez-Torres, M.5
Patel, K.6
van der Meer, A.J.7
Patick, A.K.8
Chen, A.9
Zhou, Y.10
Persson, R.11
King, B.D.12
Kauppinen, S.13
Levin, A.A.14
Hodges, M.R.15
-
41
-
-
79952717616
-
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing
-
Melo S., Villanueva A., Moutinho C., Davalos V., Spizzo R., Ivan C., Rossi S., Setien F., Casanovas O., Simo-Riudalbas L., Carmona J., Carrere J., Vidal A., Aytes A., Puertas S., Ropero S., Kalluri R., Croce C.M., Calin G.A., Esteller M. Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:4394-4399.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 4394-4399
-
-
Melo, S.1
Villanueva, A.2
Moutinho, C.3
Davalos, V.4
Spizzo, R.5
Ivan, C.6
Rossi, S.7
Setien, F.8
Casanovas, O.9
Simo-Riudalbas, L.10
Carmona, J.11
Carrere, J.12
Vidal, A.13
Aytes, A.14
Puertas, S.15
Ropero, S.16
Kalluri, R.17
Croce, C.M.18
Calin, G.A.19
Esteller, M.20
more..
-
42
-
-
70350783745
-
Structural insights into RNA processing by the human RISC-loading complex
-
Wang H.W., Noland C., Siridechadilok B., Taylor D.W., Ma E., Felderer K., Doudna J.A., Nogales E. Structural insights into RNA processing by the human RISC-loading complex. Nat. Struct. Mol. Biol. 2009, 16:1148-1153.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 1148-1153
-
-
Wang, H.W.1
Noland, C.2
Siridechadilok, B.3
Taylor, D.W.4
Ma, E.5
Felderer, K.6
Doudna, J.A.7
Nogales, E.8
-
43
-
-
43149103943
-
Targeting RNA with small molecules
-
Thomas J.R., Hergenrother P.J. Targeting RNA with small molecules. Chem. Rev. 2008, 108:1171-1224.
-
(2008)
Chem. Rev.
, vol.108
, pp. 1171-1224
-
-
Thomas, J.R.1
Hergenrother, P.J.2
-
44
-
-
77449141681
-
Small molecule modifiers of the microRNA and RNA interference pathway
-
Deiters A. Small molecule modifiers of the microRNA and RNA interference pathway. AAPS J. 2010, 12:51-60.
-
(2010)
AAPS J.
, vol.12
, pp. 51-60
-
-
Deiters, A.1
-
45
-
-
33744805399
-
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
-
Saito Y., Liang G., Egger G., Friedman J.M., Chuang J.C., Coetzee G.A., Jones P.A. Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 2006, 9:435-443.
-
(2006)
Cancer Cell
, vol.9
, pp. 435-443
-
-
Saito, Y.1
Liang, G.2
Egger, G.3
Friedman, J.M.4
Chuang, J.C.5
Coetzee, G.A.6
Jones, P.A.7
-
46
-
-
84902664243
-
A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein
-
Pop M.S., Stransky N., Garvie C.W., Theurillat J.P., Hartman E.C., Lewis T.A., Zhong C., Culyba E.K., Lin F., Daniels D.S., Pagliarini R., Ronco L., Koehler A.N., Garraway L.A. A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein. Mol. Cancer Ther. 2014, 13:1492-1502.
-
(2014)
Mol. Cancer Ther.
, vol.13
, pp. 1492-1502
-
-
Pop, M.S.1
Stransky, N.2
Garvie, C.W.3
Theurillat, J.P.4
Hartman, E.C.5
Lewis, T.A.6
Zhong, C.7
Culyba, E.K.8
Lin, F.9
Daniels, D.S.10
Pagliarini, R.11
Ronco, L.12
Koehler, A.N.13
Garraway, L.A.14
-
47
-
-
0344640906
-
Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation
-
Haggarty S.J., Koeller K.M., Wong J.C., Grozinger C.M., Schreiber S.L. Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:4389-4394.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 4389-4394
-
-
Haggarty, S.J.1
Koeller, K.M.2
Wong, J.C.3
Grozinger, C.M.4
Schreiber, S.L.5
-
48
-
-
20444479428
-
C-Myc-regulated microRNAs modulate E2F1 expression
-
O'Donnell K.A., Wentzel E.A., Zeller K.I., Dang C.V., Mendell J.T. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005, 435:839-843.
-
(2005)
Nature
, vol.435
, pp. 839-843
-
-
O'Donnell, K.A.1
Wentzel, E.A.2
Zeller, K.I.3
Dang, C.V.4
Mendell, J.T.5
-
49
-
-
84857542139
-
Small molecule inhibition of RISC loading
-
Tan G.S., Chiu C.H., Garchow B.G., Metzler D., Diamond S.L., Kiriakidou M. Small molecule inhibition of RISC loading. ACS Chem. Biol. 2012, 7:403-410.
-
(2012)
ACS Chem. Biol.
, vol.7
, pp. 403-410
-
-
Tan, G.S.1
Chiu, C.H.2
Garchow, B.G.3
Metzler, D.4
Diamond, S.L.5
Kiriakidou, M.6
-
50
-
-
84883479886
-
AC1MMYR2, an inhibitor of dicer-mediated biogenesis of Oncomir miR-21, reverses epithelial-mesenchymal transition and suppresses tumor growth and progression
-
Shi Z., Zhang J., Qian X., Han L., Zhang K., Chen L., Liu J., Ren Y., Yang M., Zhang A., Pu P., Kang C. AC1MMYR2, an inhibitor of dicer-mediated biogenesis of Oncomir miR-21, reverses epithelial-mesenchymal transition and suppresses tumor growth and progression. Cancer Res. 2013, 73:5519-5531.
-
(2013)
Cancer Res.
, vol.73
, pp. 5519-5531
-
-
Shi, Z.1
Zhang, J.2
Qian, X.3
Han, L.4
Zhang, K.5
Chen, L.6
Liu, J.7
Ren, Y.8
Yang, M.9
Zhang, A.10
Pu, P.11
Kang, C.12
-
51
-
-
84859455969
-
High-throughput luciferase reporter assay for small-molecule inhibitors of microRNA function
-
Connelly C.M., Thomas M., Deiters A. High-throughput luciferase reporter assay for small-molecule inhibitors of microRNA function. J. Biomol. Screen. 2012, 17:822-828.
-
(2012)
J. Biomol. Screen.
, vol.17
, pp. 822-828
-
-
Connelly, C.M.1
Thomas, M.2
Deiters, A.3
-
52
-
-
84876540221
-
A molecular-beacon-based screen for small molecule inhibitors of miRNA maturation
-
Bose D., Jayaraj G.G., Kumar S., Maiti S. A molecular-beacon-based screen for small molecule inhibitors of miRNA maturation. ACS Chem. Biol. 2013, 8:930-938.
-
(2013)
ACS Chem. Biol.
, vol.8
, pp. 930-938
-
-
Bose, D.1
Jayaraj, G.G.2
Kumar, S.3
Maiti, S.4
-
53
-
-
38049078739
-
A fluorescence probe for assaying micro RNA maturation
-
Davies B.P., Arenz C. A fluorescence probe for assaying micro RNA maturation. Bioorg. Med. Chem. 2008, 16:49-55.
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 49-55
-
-
Davies, B.P.1
Arenz, C.2
-
54
-
-
33748652918
-
A homogenous assay for micro RNA maturation
-
Davies B.P., Arenz C. A homogenous assay for micro RNA maturation. Angew. Chem. Int. Ed. Engl. 2006, 45:5550-5552.
-
(2006)
Angew. Chem. Int. Ed. Engl.
, vol.45
, pp. 5550-5552
-
-
Davies, B.P.1
Arenz, C.2
-
55
-
-
84856013951
-
The tuberculosis drug streptomycin as a potential cancer therapeutic: inhibition of miR-21 function by directly targeting its precursor
-
Bose D., Jayaraj G., Suryawanshi H., Agarwala P., Pore S.K., Banerjee R., Maiti S. The tuberculosis drug streptomycin as a potential cancer therapeutic: inhibition of miR-21 function by directly targeting its precursor. Angew. Chem. Int. Ed. Engl. 2012, 51:1019-1023.
-
(2012)
Angew. Chem. Int. Ed. Engl.
, vol.51
, pp. 1019-1023
-
-
Bose, D.1
Jayaraj, G.2
Suryawanshi, H.3
Agarwala, P.4
Pore, S.K.5
Banerjee, R.6
Maiti, S.7
-
56
-
-
77954071784
-
Accuracy assessment of protein-based docking programs against RNA targets
-
Li Y., Shen J., Sun X., Li W., Liu G., Tang Y. Accuracy assessment of protein-based docking programs against RNA targets. J. Chem. Inf. Model. 2010, 50:1134-1146.
-
(2010)
J. Chem. Inf. Model.
, vol.50
, pp. 1134-1146
-
-
Li, Y.1
Shen, J.2
Sun, X.3
Li, W.4
Liu, G.5
Tang, Y.6
-
57
-
-
84867438754
-
Computational analysis and predictive modeling of small molecule modulators of microRNA
-
Jamal S., Periwal V., Consortium O., Scaria V. Computational analysis and predictive modeling of small molecule modulators of microRNA. J. cheminformatics 2012, 4:16.
-
(2012)
J. cheminformatics
, vol.4
, pp. 16
-
-
Jamal, S.1
Periwal, V.2
Consortium, O.3
Scaria, V.4
-
58
-
-
84899881824
-
QSAR modeling: where have you been? Where are you going to?
-
Cherkasov A., Muratov E.N., Fourches D., Varnek A., Baskin I.I., Cronin M., Dearden J., Gramatica P., Martin Y.C., Todeschini R., Consonni V., Kuz'min V.E., Cramer R., Benigni R., Yang C., Rathman J., Terfloth L., Gasteiger J., Richard A., Tropsha A. QSAR modeling: where have you been? Where are you going to?. J. Med. Chem. 2014, 57:4977-5010.
-
(2014)
J. Med. Chem.
, vol.57
, pp. 4977-5010
-
-
Cherkasov, A.1
Muratov, E.N.2
Fourches, D.3
Varnek, A.4
Baskin, I.I.5
Cronin, M.6
Dearden, J.7
Gramatica, P.8
Martin, Y.C.9
Todeschini, R.10
Consonni, V.11
Kuz'min, V.E.12
Cramer, R.13
Benigni, R.14
Yang, C.15
Rathman, J.16
Terfloth, L.17
Gasteiger, J.18
Richard, A.19
Tropsha, A.20
more..
-
60
-
-
84899798937
-
CompaRNA: a server for continuous benchmarking of automated methods for RNA secondary structure prediction
-
Puton T., Kozlowski L.P., Rother K.M., Bujnicki J.M. CompaRNA: a server for continuous benchmarking of automated methods for RNA secondary structure prediction. Nucleic Acids Res. 2014, 42:5403-5406.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 5403-5406
-
-
Puton, T.1
Kozlowski, L.P.2
Rother, K.M.3
Bujnicki, J.M.4
-
61
-
-
84876513195
-
CompaRNA: a server for continuous benchmarking of automated methods for RNA secondary structure prediction
-
Puton T., Kozlowski L.P., Rother K.M., Bujnicki J.M. CompaRNA: a server for continuous benchmarking of automated methods for RNA secondary structure prediction. Nucleic Acids Res. 2013, 41:4307-4323.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 4307-4323
-
-
Puton, T.1
Kozlowski, L.P.2
Rother, K.M.3
Bujnicki, J.M.4
-
62
-
-
67849086863
-
CENTROIDFOLD: a web server for RNA secondary structure prediction
-
Sato K., Hamada M., Asai K., Mituyama T. CENTROIDFOLD: a web server for RNA secondary structure prediction. Nucleic Acids Res. 2009, 37:W277-W280.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. W277-W280
-
-
Sato, K.1
Hamada, M.2
Asai, K.3
Mituyama, T.4
-
63
-
-
80955123897
-
Rich parameterization improves RNA structure prediction
-
Zakov S., Goldberg Y., Elhadad M., Ziv-Ukelson M. Rich parameterization improves RNA structure prediction. J. Comput. Biol. 2011, 18:1525-1542.
-
(2011)
J. Comput. Biol.
, vol.18
, pp. 1525-1542
-
-
Zakov, S.1
Goldberg, Y.2
Elhadad, M.3
Ziv-Ukelson, M.4
-
64
-
-
79959465715
-
IPknot: fast and accurate prediction of RNA secondary structures with pseudoknots using integer programming
-
Sato K., Kato Y., Hamada M., Akutsu T., Asai K. IPknot: fast and accurate prediction of RNA secondary structures with pseudoknots using integer programming. Bioinformatics 2011, 27:i85-i93.
-
(2011)
Bioinformatics
, vol.27
, pp. i85-i93
-
-
Sato, K.1
Kato, Y.2
Hamada, M.3
Akutsu, T.4
Asai, K.5
-
65
-
-
79551480068
-
Improving the accuracy of predicting secondary structure for aligned RNA sequences
-
Hamada M., Sato K., Asai K. Improving the accuracy of predicting secondary structure for aligned RNA sequences. Nucleic Acids Res. 2011, 39:393-402.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 393-402
-
-
Hamada, M.1
Sato, K.2
Asai, K.3
-
66
-
-
66349128376
-
A local multiple alignment method for detection of non-coding RNA sequences
-
Tabei Y., Asai K. A local multiple alignment method for detection of non-coding RNA sequences. Bioinformatics 2009, 25:1498-1505.
-
(2009)
Bioinformatics
, vol.25
, pp. 1498-1505
-
-
Tabei, Y.1
Asai, K.2
-
67
-
-
58249121729
-
RNAalifold: improved consensus structure prediction for RNA alignments
-
Bernhart S.H., Hofacker I.L., Will S., Gruber A.R., Stadler P.F. RNAalifold: improved consensus structure prediction for RNA alignments. BMC Bioinf. 2008, 9:474.
-
(2008)
BMC Bioinf.
, vol.9
, pp. 474
-
-
Bernhart, S.H.1
Hofacker, I.L.2
Will, S.3
Gruber, A.R.4
Stadler, P.F.5
-
68
-
-
79954576993
-
TurboFold: iterative probabilistic estimation of secondary structures for multiple RNA sequences
-
Harmanci A.O., Sharma G., Mathews D.H. TurboFold: iterative probabilistic estimation of secondary structures for multiple RNA sequences. BMC Bioinf. 2011, 12:108.
-
(2011)
BMC Bioinf.
, vol.12
, pp. 108
-
-
Harmanci, A.O.1
Sharma, G.2
Mathews, D.H.3
-
69
-
-
40449139010
-
The MC-Fold and MC-Sym pipeline infers RNA structure from sequence data
-
Parisien M., Major F. The MC-Fold and MC-Sym pipeline infers RNA structure from sequence data. Nature 2008, 452:51-55.
-
(2008)
Nature
, vol.452
, pp. 51-55
-
-
Parisien, M.1
Major, F.2
-
70
-
-
35548950310
-
Automated de novo prediction of native-like RNA tertiary structures
-
Das R., Baker D. Automated de novo prediction of native-like RNA tertiary structures. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:14664-14669.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 14664-14669
-
-
Das, R.1
Baker, D.2
-
71
-
-
84863522073
-
Towards 3D structure prediction of large RNA molecules: an integer programming framework to insert local 3D motifs in RNA secondary structure
-
Reinharz V., Major F., Waldispuhl J. Towards 3D structure prediction of large RNA molecules: an integer programming framework to insert local 3D motifs in RNA secondary structure. Bioinformatics 2012, 28:i207-i214.
-
(2012)
Bioinformatics
, vol.28
, pp. i207-i214
-
-
Reinharz, V.1
Major, F.2
Waldispuhl, J.3
-
72
-
-
50549096615
-
IFoldRNA: three-dimensional RNA structure prediction and folding
-
Sharma S., Ding F., Dokholyan N.V. iFoldRNA: three-dimensional RNA structure prediction and folding. Bioinformatics 2008, 24:1951-1952.
-
(2008)
Bioinformatics
, vol.24
, pp. 1951-1952
-
-
Sharma, S.1
Ding, F.2
Dokholyan, N.V.3
-
73
-
-
75849116392
-
Knowledge-based instantiation of full atomic detail into coarse-grain RNA 3D structural models
-
Jonikas M.A., Radmer R.J., Altman R.B. Knowledge-based instantiation of full atomic detail into coarse-grain RNA 3D structural models. Bioinformatics 2009, 25:3259-3266.
-
(2009)
Bioinformatics
, vol.25
, pp. 3259-3266
-
-
Jonikas, M.A.1
Radmer, R.J.2
Altman, R.B.3
-
74
-
-
58249111738
-
Coarse-grained modeling of large RNA molecules with knowledge-based potentials and structural filters
-
Jonikas M.A., Radmer R.J., Laederach A., Das R., Pearlman S., Herschlag D., Altman R.B. Coarse-grained modeling of large RNA molecules with knowledge-based potentials and structural filters. RNA 2009, 15:189-199.
-
(2009)
RNA
, vol.15
, pp. 189-199
-
-
Jonikas, M.A.1
Radmer, R.J.2
Laederach, A.3
Das, R.4
Pearlman, S.5
Herschlag, D.6
Altman, R.B.7
-
75
-
-
79959292152
-
ModeRNA: a tool for comparative modeling of RNA 3D structure
-
Rother M., Rother K., Puton T., Bujnicki J.M. ModeRNA: a tool for comparative modeling of RNA 3D structure. Nucleic Acids Res. 2011, 39:4007-4022.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 4007-4022
-
-
Rother, M.1
Rother, K.2
Puton, T.3
Bujnicki, J.M.4
-
76
-
-
84864953710
-
Automated 3D structure composition for large RNAs
-
Popenda M., Szachniuk M., Antczak M., Purzycka K.J., Lukasiak P., Bartol N., Blazewicz J., Adamiak R.W. Automated 3D structure composition for large RNAs. Nucleic Acids Res. 2012, 40:e112.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. e112
-
-
Popenda, M.1
Szachniuk, M.2
Antczak, M.3
Purzycka, K.J.4
Lukasiak, P.5
Bartol, N.6
Blazewicz, J.7
Adamiak, R.W.8
-
77
-
-
3843057001
-
Validation of automated docking programs for docking and database screening against RNA drug targets
-
Detering C., Varani G. Validation of automated docking programs for docking and database screening against RNA drug targets. J. Med. Chem. 2004, 47:4188-4201.
-
(2004)
J. Med. Chem.
, vol.47
, pp. 4188-4201
-
-
Detering, C.1
Varani, G.2
-
78
-
-
32344449937
-
Docking of aminoglycosides to hydrated and flexible RNA
-
Moitessier N., Westhof E., Hanessian S. Docking of aminoglycosides to hydrated and flexible RNA. J. Med. Chem. 2006, 49:1023-1033.
-
(2006)
J. Med. Chem.
, vol.49
, pp. 1023-1033
-
-
Moitessier, N.1
Westhof, E.2
Hanessian, S.3
-
79
-
-
35248883964
-
DrugScoreRNA-knowledge-based scoring function to predict RNA-ligand interactions
-
Pfeffer P., Gohlke H. DrugScoreRNA-knowledge-based scoring function to predict RNA-ligand interactions. J. Chem. Inf. Model. 2007, 47:1868-1876.
-
(2007)
J. Chem. Inf. Model.
, vol.47
, pp. 1868-1876
-
-
Pfeffer, P.1
Gohlke, H.2
-
80
-
-
4043058000
-
Validation of an empirical RNA-ligand scoring function for fast flexible docking using Ribodock
-
Morley S.D., Afshar M. Validation of an empirical RNA-ligand scoring function for fast flexible docking using Ribodock. J. Comput. Aided Mol. Des. 2004, 18:189-208.
-
(2004)
J. Comput. Aided Mol. Des.
, vol.18
, pp. 189-208
-
-
Morley, S.D.1
Afshar, M.2
-
81
-
-
84901363730
-
RDock: a fast, versatile and open source program for docking ligands to proteins and nucleic acids
-
Ruiz-Carmona S., Alvarez-Garcia D., Foloppe N., Garmendia-Doval A.B., Juhos S., Schmidtke P., Barril X., Hubbard R.E., Morley S.D. rDock: a fast, versatile and open source program for docking ligands to proteins and nucleic acids. PLoS Comput. Biol. 2014, 10:e1003571.
-
(2014)
PLoS Comput. Biol.
, vol.10
, pp. e1003571
-
-
Ruiz-Carmona, S.1
Alvarez-Garcia, D.2
Foloppe, N.3
Garmendia-Doval, A.B.4
Juhos, S.5
Schmidtke, P.6
Barril, X.7
Hubbard, R.E.8
Morley, S.D.9
-
82
-
-
84867798654
-
Novel insights of structure-based modeling for RNA-targeted drug discovery
-
Chen L., Calin G.A., Zhang S. Novel insights of structure-based modeling for RNA-targeted drug discovery. J. Chem. Inf. Model. 2012, 52:2741-2753.
-
(2012)
J. Chem. Inf. Model.
, vol.52
, pp. 2741-2753
-
-
Chen, L.1
Calin, G.A.2
Zhang, S.3
-
83
-
-
66449110287
-
DOCK 6: combining techniques to model RNA-small molecule complexes
-
Lang P.T., Brozell S.R., Mukherjee S., Pettersen E.F., Meng E.C., Thomas V., Rizzo R.C., Case D.A., James T.L., Kuntz I.D. DOCK 6: combining techniques to model RNA-small molecule complexes. RNA 2009, 15:1219-1230.
-
(2009)
RNA
, vol.15
, pp. 1219-1230
-
-
Lang, P.T.1
Brozell, S.R.2
Mukherjee, S.3
Pettersen, E.F.4
Meng, E.C.5
Thomas, V.6
Rizzo, R.C.7
Case, D.A.8
James, T.L.9
Kuntz, I.D.10
-
84
-
-
79960431412
-
Target flexibility in RNA-ligand docking modeled by elastic potential grids
-
Kruger D.M., Bergs J., Kazemi S., Gohlke H. Target flexibility in RNA-ligand docking modeled by elastic potential grids. ACS Med. Chem. Lett. 2011, 2:489-493.
-
(2011)
ACS Med. Chem. Lett.
, vol.2
, pp. 489-493
-
-
Kruger, D.M.1
Bergs, J.2
Kazemi, S.3
Gohlke, H.4
-
85
-
-
79960562804
-
Discovery of selective bioactive small molecules by targeting an RNA dynamic ensemble
-
Stelzer A.C., Frank A.T., Kratz J.D., Swanson M.D., Gonzalez-Hernandez M.J., Lee J., Andricioaei I., Markovitz D.M., Al-Hashimi H.M. Discovery of selective bioactive small molecules by targeting an RNA dynamic ensemble. Nat. Chem. Biol. 2011, 7:553-559.
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 553-559
-
-
Stelzer, A.C.1
Frank, A.T.2
Kratz, J.D.3
Swanson, M.D.4
Gonzalez-Hernandez, M.J.5
Lee, J.6
Andricioaei, I.7
Markovitz, D.M.8
Al-Hashimi, H.M.9
-
86
-
-
47349127321
-
Docking to RNA via root-mean-square-deviation-driven energy minimization with flexible ligands and flexible targets
-
Guilbert C., James T.L. Docking to RNA via root-mean-square-deviation-driven energy minimization with flexible ligands and flexible targets. J. Chem. Inf. Model. 2008, 48:1257-1268.
-
(2008)
J. Chem. Inf. Model.
, vol.48
, pp. 1257-1268
-
-
Guilbert, C.1
James, T.L.2
-
87
-
-
44849085132
-
Bcl-2-targeted antisense therapy (Oblimersen sodium): towards clinical reality
-
Moreira J.N., Santos A., Simoes S. Bcl-2-targeted antisense therapy (Oblimersen sodium): towards clinical reality. Rev. Recent Clin. Trials 2006, 1:217-235.
-
(2006)
Rev. Recent Clin. Trials
, vol.1
, pp. 217-235
-
-
Moreira, J.N.1
Santos, A.2
Simoes, S.3
-
88
-
-
79960104144
-
MicroRNAs in development and disease
-
Sayed D., Abdellatif M. MicroRNAs in development and disease. Physiol. Rev. 2011, 91:827-887.
-
(2011)
Physiol. Rev.
, vol.91
, pp. 827-887
-
-
Sayed, D.1
Abdellatif, M.2
-
89
-
-
77953312157
-
Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma
-
Young D.D., Connelly C.M., Grohmann C., Deiters A. Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma. J. Am. Chem. Soc. 2010, 132:7976-7981.
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 7976-7981
-
-
Young, D.D.1
Connelly, C.M.2
Grohmann, C.3
Deiters, A.4
-
90
-
-
77955287613
-
Identification of small molecules that suppress microRNA function and reverse tumorigenesis
-
Watashi K., Yeung M.L., Starost M.F., Hosmane R.S., Jeang K.T. Identification of small molecules that suppress microRNA function and reverse tumorigenesis. J. Biol. Chem. 2010, 285:24707-24716.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 24707-24716
-
-
Watashi, K.1
Yeung, M.L.2
Starost, M.F.3
Hosmane, R.S.4
Jeang, K.T.5
-
91
-
-
84655167637
-
Aza-flavanones as potent cross-species microRNA inhibitors that arrest cell cycle
-
Chandrasekhar S., Pushpavalli S.N., Chatla S., Mukhopadhyay D., Ganganna B., Vijeender K., Srihari P., Reddy C.R., Janaki Ramaiah M., Bhadra U. Aza-flavanones as potent cross-species microRNA inhibitors that arrest cell cycle. Bioorg. Med. Chem. Lett. 2012, 22:645-648.
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 645-648
-
-
Chandrasekhar, S.1
Pushpavalli, S.N.2
Chatla, S.3
Mukhopadhyay, D.4
Ganganna, B.5
Vijeender, K.6
Srihari, P.7
Reddy, C.R.8
Janaki Ramaiah, M.9
Bhadra, U.10
-
92
-
-
84896969123
-
Targeting the production of oncogenic microRNAs with multimodal synthetic small molecules
-
Vo D.D., Staedel C., Zehnacker L., Benhida R., Darfeuille F., Duca M. Targeting the production of oncogenic microRNAs with multimodal synthetic small molecules. ACS Chem. Biol. 2014, 9:711-721.
-
(2014)
ACS Chem. Biol.
, vol.9
, pp. 711-721
-
-
Vo, D.D.1
Staedel, C.2
Zehnacker, L.3
Benhida, R.4
Darfeuille, F.5
Duca, M.6
-
93
-
-
84897024057
-
Sequence-based design of bioactive small molecules that target precursor microRNAs
-
Velagapudi S.P., Gallo S.M., Disney M.D. Sequence-based design of bioactive small molecules that target precursor microRNAs. Nat. Chem. Biol. 2014, 10:291-297.
-
(2014)
Nat. Chem. Biol.
, vol.10
, pp. 291-297
-
-
Velagapudi, S.P.1
Gallo, S.M.2
Disney, M.D.3
-
94
-
-
84871027932
-
Xanthone derivatives as potential inhibitors of miRNA processing by human Dicer: targeting secondary structures of pre-miRNA by small molecules
-
Murata A., Fukuzumi T., Umemoto S., Nakatani K. Xanthone derivatives as potential inhibitors of miRNA processing by human Dicer: targeting secondary structures of pre-miRNA by small molecules. Bioorg. Med. Chem. Lett. 2013, 23:252-255.
-
(2013)
Bioorg. Med. Chem. Lett.
, vol.23
, pp. 252-255
-
-
Murata, A.1
Fukuzumi, T.2
Umemoto, S.3
Nakatani, K.4
-
95
-
-
49449096792
-
A small molecule enhances RNA interference and promotes microRNA processing
-
Shan G., Li Y., Zhang J., Li W., Szulwach K.E., Duan R., Faghihi M.A., Khalil A.M., Lu L., Paroo Z., Chan A.W., Shi Z., Liu Q., Wahlestedt C., He C., Jin P. A small molecule enhances RNA interference and promotes microRNA processing. Nat. Biotechnol. 2008, 26:933-940.
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 933-940
-
-
Shan, G.1
Li, Y.2
Zhang, J.3
Li, W.4
Szulwach, K.E.5
Duan, R.6
Faghihi, M.A.7
Khalil, A.M.8
Lu, L.9
Paroo, Z.10
Chan, A.W.11
Shi, Z.12
Liu, Q.13
Wahlestedt, C.14
He, C.15
Jin, P.16
-
96
-
-
84862183043
-
A universal activator of microRNAs identified from photoreaction products
-
Chen X., Huang C., Zhang W., Wu Y., Chen X., Zhang C.Y., Zhang Y. A universal activator of microRNAs identified from photoreaction products. Chem. Commun. 2012, 48:6432-6434.
-
(2012)
Chem. Commun.
, vol.48
, pp. 6432-6434
-
-
Chen, X.1
Huang, C.2
Zhang, W.3
Wu, Y.4
Chen, X.5
Zhang, C.Y.6
Zhang, Y.7
-
97
-
-
80052478946
-
MicroRNA-10b: a new marker or the marker of pancreatic ductal adenocarcinoma?
-
Setoyama T., Zhang X., Natsugoe S., Calin G.A. microRNA-10b: a new marker or the marker of pancreatic ductal adenocarcinoma?. Clin. Cancer Res. 2011, 17:5527-5529.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 5527-5529
-
-
Setoyama, T.1
Zhang, X.2
Natsugoe, S.3
Calin, G.A.4
-
98
-
-
77954230727
-
MiR-10b targets Tiam1: implications for Rac activation and carcinoma migration
-
Moriarty C.H., Pursell B., Mercurio A.M. miR-10b targets Tiam1: implications for Rac activation and carcinoma migration. J. Biol. Chem. 2010, 285:20541-20546.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 20541-20546
-
-
Moriarty, C.H.1
Pursell, B.2
Mercurio, A.M.3
-
99
-
-
84883470363
-
MicroRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2
-
Liao W.T., Li T.T., Wang Z.G., Wang S.Y., He M.R., Ye Y.P., Qi L., Cui Y.M., Wu P., Jiao H.L., Zhang C., Xie Y.J., Wang J.X., Ding Y.Q. microRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2. Clin. Cancer Res. 2013, 19:4662-4672.
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 4662-4672
-
-
Liao, W.T.1
Li, T.T.2
Wang, Z.G.3
Wang, S.Y.4
He, M.R.5
Ye, Y.P.6
Qi, L.7
Cui, Y.M.8
Wu, P.9
Jiao, H.L.10
Zhang, C.11
Xie, Y.J.12
Wang, J.X.13
Ding, Y.Q.14
-
100
-
-
84886052756
-
Up-regulation of miR-224 promotes cancer cell proliferation and invasion and predicts relapse of colorectal cancer
-
Zhang G.J., Zhou H., Xiao H.X., Li Y., Zhou T. Up-regulation of miR-224 promotes cancer cell proliferation and invasion and predicts relapse of colorectal cancer. Cancer Cell Int. 2013, 13:104.
-
(2013)
Cancer Cell Int.
, vol.13
, pp. 104
-
-
Zhang, G.J.1
Zhou, H.2
Xiao, H.X.3
Li, Y.4
Zhou, T.5
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