Docking of aminoglycosides to hydrated and flexible RNA

Journal of Medicinal Chemistry

Volumn 49, Issue 3, 2006, Pages 1023-1033

  Moitessier, Nicolas ^a   Westhof, Eric ^c   Hanessian, Stephen ^b  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; DOCKING PROTEIN; GENTAMICIN; NEOMYCIN; RNA; TOBRAMYCIN;

ARTICLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; HYDRATION; LIGAND BINDING; MACROMOLECULE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PROTEIN CONFORMATION; RNA METABOLISM; SIMULATION; X RAY CRYSTALLOGRAPHY;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; RNA; THERMODYNAMICS; WATER;

EID: 32344449937     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0508437     Document Type: Article

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