메뉴 건너뛰기




Volumn 9, Issue 3, 2014, Pages 711-721

Targeting the production of oncogenic MicroRNAs with multimodal synthetic small molecules

Author keywords

[No Author keywords available]

Indexed keywords

BOC NEOMYCIN A; BOC NEOMYCIN BIG; BOC NEOMYCIN C; BOC NEOMYCIN D3; BOC NEOMYCIN D4; BOC NEOMYCIN G; BOC NEOMYCIN HB; BOC NEOMYCIN HB AR; BOC NEOMYCIN S; BOC NEOMYCIN U; MICRORNA; MICRORNA 372; MICRORNA 373; NEAMINE; NEOMYCIN; NEOMYCIN BIG; NEOMYCIN CYTOSIN; NEOMYCIN D4; NEOMYCIN G; NEOMYCIN HB; NEOMYCIN HBBAR; NEOMYCIN S; NEOMYCIN U; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; LIGAND; MIRN372 MICRORNA, HUMAN; MIRN373 MICRORNA, HUMAN; MOLECULAR LIBRARY;

EID: 84896969123     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400668h     Document Type: Article
Times cited : (98)

References (48)
  • 1
    • 53549101290 scopus 로고    scopus 로고
    • The evolution of our thinking about microRNAs
    • Ambros, V. (2008) The evolution of our thinking about microRNAs Nat. Med. 14, 1036-1040
    • (2008) Nat. Med. , vol.14 , pp. 1036-1040
    • Ambros, V.1
  • 2
    • 36749026906 scopus 로고    scopus 로고
    • Switching from repression to activation: MicroRNAs can up-regulate translation
    • Vasudevan, S., Tong, Y., and Steitz, J. A. (2007) Switching from repression to activation: microRNAs can up-regulate translation Science 318, 1931-1934
    • (2007) Science , vol.318 , pp. 1931-1934
    • Vasudevan, S.1    Tong, Y.2    Steitz, J.A.3
  • 4
    • 84862243555 scopus 로고    scopus 로고
    • Causes and consequences of microRNA dysregulation
    • Iorio, M. V. and Croce, C. M. (2012) Causes and consequences of microRNA dysregulation Cancer J. 18, 215-222
    • (2012) Cancer J. , vol.18 , pp. 215-222
    • Iorio, M.V.1    Croce, C.M.2
  • 6
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin, G. A. and Croce, C. M. (2006) MicroRNA signatures in human cancers Nat. Rev. Cancer 6, 857-866
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 7
    • 72949098057 scopus 로고    scopus 로고
    • Therapeutic microRNA strategies in human cancer
    • Li, C., Feng, Y., Coukos, G., and Zhang, L. (2009) Therapeutic microRNA strategies in human cancer AAPS J. 11, 747-757
    • (2009) AAPS J. , vol.11 , pp. 747-757
    • Li, C.1    Feng, Y.2    Coukos, G.3    Zhang, L.4
  • 8
    • 77449141681 scopus 로고    scopus 로고
    • Small molecule modifiers of the microRNA and RNA interference pathway
    • Deiters, A. (2010) Small molecule modifiers of the microRNA and RNA interference pathway AAPS J. 12, 51-60
    • (2010) AAPS J. , vol.12 , pp. 51-60
    • Deiters, A.1
  • 9
    • 84885020670 scopus 로고    scopus 로고
    • Perspectives in targeting miRNA function
    • Schoniger, C. and Arenz, C. (2013) Perspectives in targeting miRNA function Bioorg. Med. Chem. 21, 6115-6118
    • (2013) Bioorg. Med. Chem. , vol.21 , pp. 6115-6118
    • Schoniger, C.1    Arenz, C.2
  • 12
    • 65849267719 scopus 로고    scopus 로고
    • Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells
    • Wickramasinghe, N. S., Manavalan, T. T., Dougherty, S. M., Riggs, K. A., Li, Y., and Klinge, C. M. (2009) Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells Nucleic Acids Res. 37, 2584-2595
    • (2009) Nucleic Acids Res. , vol.37 , pp. 2584-2595
    • Wickramasinghe, N.S.1    Manavalan, T.T.2    Dougherty, S.M.3    Riggs, K.A.4    Li, Y.5    Klinge, C.M.6
  • 13
    • 77953312157 scopus 로고    scopus 로고
    • Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma
    • Young, D. D., Connelly, C. M., Grohmann, C., and Deiters, A. (2010) Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma J. Am. Chem. Soc. 132, 7976-7981
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 7976-7981
    • Young, D.D.1    Connelly, C.M.2    Grohmann, C.3    Deiters, A.4
  • 15
    • 84856013951 scopus 로고    scopus 로고
    • The tuberculosis drug streptomycin as a potential cancer therapeutic: Inhibition of miR-21 function by directly targeting its precursor
    • Bose, D., Jayaraj, G., Suryawanshi, H., Agarwala, P., Pore, S. K., Banerjee, R., and Maiti, S. (2012) The tuberculosis drug streptomycin as a potential cancer therapeutic: inhibition of miR-21 function by directly targeting its precursor Angew. Chem., Int. Ed. 51, 1019-1023
    • (2012) Angew. Chem., Int. Ed. , vol.51 , pp. 1019-1023
    • Bose, D.1    Jayaraj, G.2    Suryawanshi, H.3    Agarwala, P.4    Pore, S.K.5    Banerjee, R.6    Maiti, S.7
  • 16
    • 84856650429 scopus 로고    scopus 로고
    • Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing
    • Maiti, M., Nauwelaerts, K., and Herdewijn, P. (2012) Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing Bioorg. Med. Chem. Lett. 22, 1709-1711
    • (2012) Bioorg. Med. Chem. Lett. , vol.22 , pp. 1709-1711
    • Maiti, M.1    Nauwelaerts, K.2    Herdewijn, P.3
  • 17
    • 77952584924 scopus 로고    scopus 로고
    • Targeting microRNAs with small molecules: From dream to reality
    • Zhang, S., Chen, L., Jung, E. J., and Calin, G. A. (2010) Targeting microRNAs with small molecules: from dream to reality Clin. Pharm. Ther. 87, 754-758
    • (2010) Clin. Pharm. Ther. , vol.87 , pp. 754-758
    • Zhang, S.1    Chen, L.2    Jung, E.J.3    Calin, G.A.4
  • 18
    • 76649106069 scopus 로고    scopus 로고
    • MiR-372 regulates cell cycle and apoptosis of ags human gastric cancer cell line through direct regulation of LATS2
    • Cho, W. J., Shin, J. M., Kim, J. S., Lee, M. R., Hong, K. S., Lee, J. H., Koo, K. H., Park, J. W., and Kim, K. S. (2009) miR-372 regulates cell cycle and apoptosis of ags human gastric cancer cell line through direct regulation of LATS2 Mol. Cells 28, 521-527
    • (2009) Mol. Cells , vol.28 , pp. 521-527
    • Cho, W.J.1    Shin, J.M.2    Kim, J.S.3    Lee, M.R.4    Hong, K.S.5    Lee, J.H.6    Koo, K.H.7    Park, J.W.8    Kim, K.S.9
  • 20
    • 67651045805 scopus 로고    scopus 로고
    • MicroRNA-373 (miR-373) post-transcriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in human esophageal cancer
    • Lee, K. H., Goan, Y. G., Hsiao, M., Lee, C. H., Jian, S. H., Lin, J. T., Chen, Y. L., and Lu, P. J. (2009) MicroRNA-373 (miR-373) post-transcriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in human esophageal cancer Exp. Cell. Res. 315, 2529-2538
    • (2009) Exp. Cell. Res. , vol.315 , pp. 2529-2538
    • Lee, K.H.1    Goan, Y.G.2    Hsiao, M.3    Lee, C.H.4    Jian, S.H.5    Lin, J.T.6    Chen, Y.L.7    Lu, P.J.8
  • 21
    • 77949795326 scopus 로고    scopus 로고
    • The two stem cell microRNA gene clusters C19MC and miR-371-3 are activated by specific chromosomal rearrangements in a subgroup of thyroid adenomas
    • Rippe, V., Dittberner, L., Lorenz, V. N., Drieschner, N., Nimzyk, R., Sendt, W., Junker, K., Belge, G., and Bullerdiek, J. (2010) The two stem cell microRNA gene clusters C19MC and miR-371-3 are activated by specific chromosomal rearrangements in a subgroup of thyroid adenomas PloS One 5, e9485
    • (2010) PloS One , vol.5 , pp. 9485
    • Rippe, V.1    Dittberner, L.2    Lorenz, V.N.3    Drieschner, N.4    Nimzyk, R.5    Sendt, W.6    Junker, K.7    Belge, G.8    Bullerdiek, J.9
  • 22
    • 84862167282 scopus 로고    scopus 로고
    • Helicobacter pylori interferes with an embryonic stem cell micro RNA cluster to block cell cycle progression
    • Belair, C., Baud, J., Chabas, S., Sharma, C. M., Vogel, J., Staedel, C., and Darfeuille, F. (2011) Helicobacter pylori interferes with an embryonic stem cell micro RNA cluster to block cell cycle progression Silence 2, 7
    • (2011) Silence , vol.2 , pp. 7
    • Belair, C.1    Baud, J.2    Chabas, S.3    Sharma, C.M.4    Vogel, J.5    Staedel, C.6    Darfeuille, F.7
  • 24
    • 78650733766 scopus 로고    scopus 로고
    • Targeting DNA base pair mismatch with artificial nucleobases. Advances and perspectives in triple helix strategy
    • Malnuit, V., Duca, M., and Benhida, R. (2011) Targeting DNA base pair mismatch with artificial nucleobases. Advances and perspectives in triple helix strategy Org. Biomol. Chem. 9, 326-336
    • (2011) Org. Biomol. Chem. , vol.9 , pp. 326-336
    • Malnuit, V.1    Duca, M.2    Benhida, R.3
  • 25
    • 77955839382 scopus 로고    scopus 로고
    • Design of novel RNA ligands that bind stem-bulge HIV-1 TAR RNA
    • Duca, M., Malnuit, V., Barbault, F., and Benhida, R. (2010) Design of novel RNA ligands that bind stem-bulge HIV-1 TAR RNA Chem. Commun. 46, 6162-6164
    • (2010) Chem. Commun. , vol.46 , pp. 6162-6164
    • Duca, M.1    Malnuit, V.2    Barbault, F.3    Benhida, R.4
  • 26
    • 43149103943 scopus 로고    scopus 로고
    • Targeting RNA with small molecules
    • Thomas, J. R. and Hergenrother, P. J. (2008) Targeting RNA with small molecules Chem. Rev. 108, 1171-1224
    • (2008) Chem. Rev. , vol.108 , pp. 1171-1224
    • Thomas, J.R.1    Hergenrother, P.J.2
  • 27
    • 84856134636 scopus 로고    scopus 로고
    • Recent advances in developing small molecules targeting RNA
    • Guan, L. and Disney, M. D. (2012) Recent advances in developing small molecules targeting RNA ACS Chem. Biol. 7, 73-86
    • (2012) ACS Chem. Biol. , vol.7 , pp. 73-86
    • Guan, L.1    Disney, M.D.2
  • 30
    • 0027370433 scopus 로고
    • Small molecules that selectively block RNA binding of HIV-1 Rev protein inhibit Rev function and viral production
    • Zapp, M. L., Stern, S., and Green, M. R. (1993) Small molecules that selectively block RNA binding of HIV-1 Rev protein inhibit Rev function and viral production Cell 74, 969-978
    • (1993) Cell , vol.74 , pp. 969-978
    • Zapp, M.L.1    Stern, S.2    Green, M.R.3
  • 32
    • 0142011647 scopus 로고    scopus 로고
    • Targeting RNA with small molecules
    • Tor, Y. (2003) Targeting RNA with small molecules ChemBioChem 4, 998-1007
    • (2003) ChemBioChem , vol.4 , pp. 998-1007
    • Tor, Y.1
  • 33
    • 0032513007 scopus 로고    scopus 로고
    • Aminoglycoside binding to the hammerhead ribozyme: A general model for the interaction of cationic antibiotics with RNA
    • Hermann, T. and Westhof, E. (1998) Aminoglycoside binding to the hammerhead ribozyme: a general model for the interaction of cationic antibiotics with RNA J. Mol. Biol. 276, 903-912
    • (1998) J. Mol. Biol. , vol.276 , pp. 903-912
    • Hermann, T.1    Westhof, E.2
  • 34
    • 0031894779 scopus 로고    scopus 로고
    • Modeling RNA-ligand interactions: The Rev-binding element RNA-aminoglycoside complex
    • Leclerc, F. and Cedergren, R. (1998) Modeling RNA-ligand interactions: the Rev-binding element RNA-aminoglycoside complex J. Med. Chem. 41, 175-182
    • (1998) J. Med. Chem. , vol.41 , pp. 175-182
    • Leclerc, F.1    Cedergren, R.2
  • 35
    • 33749669210 scopus 로고    scopus 로고
    • A tale of two targets: Differential RNA selectivity of nucleobase-aminoglycoside conjugates
    • Blount, K. F. and Tor, Y. (2006) A tale of two targets: differential RNA selectivity of nucleobase-aminoglycoside conjugates ChemBioChem 7, 1612-1621
    • (2006) ChemBioChem , vol.7 , pp. 1612-1621
    • Blount, K.F.1    Tor, Y.2
  • 36
    • 0035929187 scopus 로고    scopus 로고
    • Incorporation of a novel nucleobase allows stable oligonucleotide- directed triple helix formation at the target sequence containing a purine.pyrimidine interruption
    • Guianvarc'h, D., Benhida, R., Fourrey, J. L., Maurisse, R., and Sun, J. S. (2001) Incorporation of a novel nucleobase allows stable oligonucleotide- directed triple helix formation at the target sequence containing a purine.pyrimidine interruption Chem. Commun. 1814-1815
    • (2001) Chem. Commun. , pp. 1814-1815
    • Guianvarch, D.1    Benhida, R.2    Fourrey, J.L.3    Maurisse, R.4    Sun, J.S.5
  • 37
    • 0038143610 scopus 로고    scopus 로고
    • Design of artificial nucleobases for the recognition of the at inversion by triple-helix forming oligonucleotides: A structure-stability relationship study and neighbour bases effect
    • Guianvarc'h, D., Fourrey, J. L., Maurisse, R., Sun, J. S., and Benhida, R. (2003) Design of artificial nucleobases for the recognition of the AT inversion by triple-helix forming oligonucleotides: a structure-stability relationship study and neighbour bases effect Bioorg. Med. Chem. 11, 2751-2759
    • (2003) Bioorg. Med. Chem. , vol.11 , pp. 2751-2759
    • Guianvarch, D.1    Fourrey, J.L.2    Maurisse, R.3    Sun, J.S.4    Benhida, R.5
  • 38
    • 0033550309 scopus 로고    scopus 로고
    • NMR recognition studies of C·G base pairs by new easily accessible heterobicyclic systems
    • Lecubin, F., Benhida, R., Fourrey, J. L., and Sun, J. S. (1999) NMR recognition studies of C·G base pairs by new easily accessible heterobicyclic systems Tetrahedron Lett. 40, 8085-8088
    • (1999) Tetrahedron Lett. , vol.40 , pp. 8085-8088
    • Lecubin, F.1    Benhida, R.2    Fourrey, J.L.3    Sun, J.S.4
  • 39
    • 2342526554 scopus 로고    scopus 로고
    • CG base pair recognition by substituted phenylimidazole nucleosides
    • Wang, W., Purwanto, M. G., and Weisz, K. (2004) CG base pair recognition by substituted phenylimidazole nucleosides Org. Biomol. Chem. 2, 1194-1198
    • (2004) Org. Biomol. Chem. , vol.2 , pp. 1194-1198
    • Wang, W.1    Purwanto, M.G.2    Weisz, K.3
  • 40
    • 0029586169 scopus 로고
    • Design of a novel artificial nucleobase for the selective formation of a triple-complex with a cytosine-guanine base pair
    • Sasaki, S., Nakashima, S., Nagatsugi, F., Tanaka, Y., Hisatome, M., and Maeda, M. (1995) Design of a novel artificial nucleobase for the selective formation of a triple-complex with a cytosine-guanine base pair Tetrahedron Lett. 36, 9521-9524
    • (1995) Tetrahedron Lett. , vol.36 , pp. 9521-9524
    • Sasaki, S.1    Nakashima, S.2    Nagatsugi, F.3    Tanaka, Y.4    Hisatome, M.5    Maeda, M.6
  • 41
    • 0001494518 scopus 로고
    • Recognition of all four base pairs of double-helical DNA by triple-helix formation: Design of nonnatural deoxyribonucleosides for pyrimidine.cntdot. purine base pair binding
    • Griffin, L. C., Kiessling, L. L., Beal, P. A., Gillespie, P., and Dervan, P. B. (1992) Recognition of all four base pairs of double-helical DNA by triple-helix formation: design of nonnatural deoxyribonucleosides for pyrimidine.cntdot.purine base pair binding J. Am. Chem. Soc. 114, 7976-7982
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 7976-7982
    • Griffin, L.C.1    Kiessling, L.L.2    Beal, P.A.3    Gillespie, P.4    Dervan, P.B.5
  • 42
    • 33748652918 scopus 로고    scopus 로고
    • A homogenous assay for micro RNA maturation
    • Davies, B. P. and Arenz, C. (2006) A homogenous assay for micro RNA maturation Angew. Chem., Int. Ed. 45, 5550-5552
    • (2006) Angew. Chem., Int. Ed. , vol.45 , pp. 5550-5552
    • Davies, B.P.1    Arenz, C.2
  • 43
    • 38049078739 scopus 로고    scopus 로고
    • A fluorescence probe for assaying micro RNA maturation
    • Davies, B. P. and Arenz, C. (2008) A fluorescence probe for assaying micro RNA maturation Bioorg. Med. Chem. 16, 49-55
    • (2008) Bioorg. Med. Chem. , vol.16 , pp. 49-55
    • Davies, B.P.1    Arenz, C.2
  • 44
    • 84856665482 scopus 로고    scopus 로고
    • Neomycin-phenolic conjugates: Polycationic amphiphiles with broad-spectrum antibacterial activity, low hemolytic activity and weak serum protein binding
    • Findlay, B., Zhanel, G. G., and Schweizer, F. (2012) Neomycin-phenolic conjugates: polycationic amphiphiles with broad-spectrum antibacterial activity, low hemolytic activity and weak serum protein binding Bioorg. Med. Chem. Lett. 22, 1499-1503
    • (2012) Bioorg. Med. Chem. Lett. , vol.22 , pp. 1499-1503
    • Findlay, B.1    Zhanel, G.G.2    Schweizer, F.3
  • 45
    • 13744261523 scopus 로고    scopus 로고
    • RNA-selective modification by a platinum(II) complex conjugated to amino- and guanidinoglycosides
    • Boer, J., Blount, K. F., Luedtke, N. W., Elson-Schwab, L., and Tor, Y. (2005) RNA-selective modification by a platinum(II) complex conjugated to amino- and guanidinoglycosides Angew. Chem., Int. Ed. 44, 927-932
    • (2005) Angew. Chem., Int. Ed. , vol.44 , pp. 927-932
    • Boer, J.1    Blount, K.F.2    Luedtke, N.W.3    Elson-Schwab, L.4    Tor, Y.5
  • 46
    • 0141483331 scopus 로고    scopus 로고
    • RNA-ligand interactions: Affinity and specificity of aminoglycoside dimers and acridine conjugates to the HIV-1 Rev response element
    • Luedtke, N. W., Liu, Q., and Tor, Y. (2003) RNA-ligand interactions: affinity and specificity of aminoglycoside dimers and acridine conjugates to the HIV-1 Rev response element Biochemistry 42, 11391-11403
    • (2003) Biochemistry , vol.42 , pp. 11391-11403
    • Luedtke, N.W.1    Liu, Q.2    Tor, Y.3
  • 47
    • 24744443295 scopus 로고    scopus 로고
    • Size-specific ligands for RNA hairpin loops
    • Thomas, J. R., Liu, X., and Hergenrother, P. J. (2005) Size-specific ligands for RNA hairpin loops J. Am. Chem. Soc. 127, 12434-12435
    • (2005) J. Am. Chem. Soc. , vol.127 , pp. 12434-12435
    • Thomas, J.R.1    Liu, X.2    Hergenrother, P.J.3
  • 48
    • 84865062501 scopus 로고    scopus 로고
    • Molecular pathways: MicroRNAs as cancer therapeutics
    • Melo, S. A. and Kalluri, R. (2012) Molecular pathways: microRNAs as cancer therapeutics Clin. Cancer Res. 18, 4234-4239
    • (2012) Clin. Cancer Res. , vol.18 , pp. 4234-4239
    • Melo, S.A.1    Kalluri, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.