Identification of small molecules that suppress microRNA function and reverse tumorigenesis

Journal of Biological Chemistry

Volumn 285, Issue 32, 2010, Pages 24707-24716

  Watashi, Koichi ^a   Yeung, Man Lung ^a   Starost, Matthew F ^a   Hosmane, Ramachandra S ^b   Jeang, Kuan Teh ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENETIC ENGINEERING; MOLECULES; RNA;

CELL-BASED; CHEMICAL LIBRARIES; CULTURED CELL; MICRORNAS; POST-TRANSCRIPTIONAL GENE SILENCING; RNA INTERFERENCE; SMALL MOLECULES; SMALL RNA; TUMOR GROWTH; TUMORIGENESIS; VIRAL DISEASE; WIDE SPECTRUM;

CHEMICAL COMPOUNDS;

ACRIFLAVINE; ARGONAUTE 2 PROTEIN; DICER; MICRORNA; POLYLYSINE; RNA INDUCED SILENCING COMPLEX; SHORT HAIRPIN RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; FEMALE; GENE SILENCING; GROWTH INHIBITION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; 3T3 CELL LINE; ANIMAL; BIOLOGICAL MODEL; CANCER TRANSPLANTATION; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENETICS; HELA CELL LINE; METABOLISM; NEOPLASMS; NUDE MOUSE; PHENOTYPE;

3T3 CELLS; ANIMALS; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HELA CELLS; HUMANS; MICE; MICE, NUDE; MICRORNAS; MODELS, BIOLOGICAL; NEOPLASM TRANSPLANTATION; NEOPLASMS; PHENOTYPE; RNA INTERFERENCE;

EID: 77955287613     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.062976     Document Type: Article

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