The Bcl-2 family: Structures, interactions and targets for drug discovery

Apoptosis

Volumn 20, Issue 2, 2015, Pages 136-150

  Kvansakul, Marc ^a   Hinds, Mark G ^b  

^a LA TROBE UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Apoptosis; Bcl 2; Cancer; Drug discovery; Virus

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; BECLIN 1; BH3 PROTEIN; NAVITOCLAX; PROTEIN BCL 2; VENETOCLAX; VIRUS PROTEIN; ANTINEOPLASTIC AGENT;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SURVIVAL; DEATH; DRUG PROTEIN BINDING; HUMAN; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; DRUG DEVELOPMENT; NEOPLASMS; PHYSIOLOGY; PROTEIN ANALYSIS; PROTEIN DOMAIN;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; DRUG DISCOVERY; HUMANS; MODELS, MOLECULAR; NEOPLASMS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84922076832     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-014-1051-7     Document Type: Article

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