Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity

Journal of Cell Biology

Volumn 162, Issue 5, 2003, Pages 877-887

  Wilson Annan, Julie ^b   O'Reilly, Lorraine A ^b   Crawford, Simon A ^b   Hausmann, George ^b   Beaumont, Jennifer G ^b   Parma, Loes P ^b   Chen, Lin ^b   Lackmann, Martin ^b   Lithgow, Trevor ^b   Hinds, Mark G ^b   Day, Catherine L ^a   Adams, Jerry M ^b   Huang, David C S ^b  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b NONE

Author keywords

Apoptosis; Bcl 2; BH3; Mitochondria; Targeting

Indexed keywords

BH3 PROTEIN; BIM PROTEIN; MEMBRANE PROTEIN; PROTEIN; PROTEIN BCL 2; PROTEIN BCL W; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL LYSATE; CELL ORGANELLE; CELL SURVIVAL; CHIMERA; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIGAND BINDING; MEMBRANE BINDING; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL FRACTIONATION; CELL MEMBRANE; CELL SURVIVAL; HELA CELLS; HUMANS; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RECOMBINANT FUSION PROTEINS;

INSERTION SEQUENCES;

EID: 0041384326     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200302144     Document Type: Article

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