Inhibition of apoptosis and NF-κB activation by vaccinia protein N1 occur via distinct binding surfaces and make different contributions to virulence

PLoS Pathogens

Volumn 7, Issue 12, 2011, Pages

  de Motes, Carlos Maluquer ^a   Cooray, Samantha ^a,d   Ren, Hongwei ^a   Almeida, Gabriel M F ^a,e   McGourty, Kieran ^a   Bahar, Mohammad W ^b   Stuart, David I ^b,c   Grimes, Jonathan M ^b,c   Graham, Stephen C ^b,f   Smith, Geoffrey L ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c DIAMOND LIGHT SOURCE LTD   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^f UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BCL 2; UNCLASSIFIED DRUG; VACCINIA VIRUS PROTEIN N1; VIRUS PROTEIN;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CRYSTALLOGRAPHY; GENE MUTATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; INOCULATION; MOUSE; MUTAGENESIS; NONHUMAN; VACCINIA VIRUS; VIRUS INFECTION; VIRUS STRAIN; VIRUS VIRULENCE; WILD TYPE;

MUS; VACCINIA VIRUS;

EID: 84855265610     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002430     Document Type: Article

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