Mapping the IκB kinase β (IKKβ)-binding interface of the B14 protein, a vaccinia virus inhibitor of IKKβ-mediated activation of nuclear factor κB

Journal of Biological Chemistry

Volumn 286, Issue 23, 2011, Pages 20727-20735

  Benfield, Camilla T O ^a   Mansur, Daniel S ^a,e   McCoy, Laura E ^a,f   Ferguson, Brian J ^a   Bahar, Mohammad W ^b   Oldring, Asa P ^b,g   Grimes, Jonathan M ^b,c   Stuart, David I ^b,c   Graham, Stephen C ^b,d   Smith, Geoffrey L ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c DIAMOND LIGHT SOURCE LTD   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

^g Thermo Fisher Scientific   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SUBSTITUTION; BINDING INTERFACE; CRYSTALLOGRAPHIC STUDIES; DIMER INTERFACE; HOMODIMERIZATION; HOMODIMERS; IMMUNE RESPONSE; MONOMER-DIMER EQUILIBRIUM; MULTI-ANGLE LIGHT SCATTERINGS; NUCLEAR FACTORS; NUCLEAR TRANSLOCATIONS; PRO-INFLAMMATORY STIMULI; PROTEIN-PROTEIN INTERACTIONS; SELF-ASSOCIATIONS; VACCINIA VIRUS;

AMINO ACIDS; ASSOCIATION REACTIONS; DIMERIZATION; DIMERS; ENZYMES; GENES; TRANSCRIPTION; TRANSCRIPTION FACTORS;

VIRUSES;

I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN B14; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CONTROLLED STUDY; DIMERIZATION; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; VACCINIA VIRUS; ACTIVE TRANSPORT; CELL NUCLEUS; CELL STRAIN HEK293; CHEMICAL PHENOMENA; GENETICS; METABOLISM; MISSENSE MUTATION; PROTEIN MULTIMERIZATION;

VACCINIA VIRUS;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID SUBSTITUTION; CELL NUCLEUS; HEK293 CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; I-KAPPA B KINASE; MUTATION, MISSENSE; NF-KAPPA B; PROTEIN MULTIMERIZATION; VACCINIA VIRUS; VIRAL PROTEINS;

EID: 79957987060     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.231381     Document Type: Article

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