Structural biology of the Bcl-2 family of proteins

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1644, Issue 2-3, 2004, Pages 83-94

  Petros, Andrew M ^a   Olejniczak, Edward T ^a   Fesik, Stephen W ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Apoptosis; Bak; Bax; Bcl 2; Bcl w; Bcl xL; Bid

Indexed keywords

BACTERIAL TOXIN; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL W; PROTEIN BCL XL; PROTEIN BID;

ALPHA HELIX; AMINO ACID SEQUENCE; APOPTOSIS; ARTIFICIAL MEMBRANE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CYTOPLASM; DATA ANALYSIS; HUMAN; HUMAN HERPESVIRUS 8; HYDROPHOBICITY; MITOCHONDRION; MOLECULAR MIMICRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS; SURFACE PROPERTY; THREE DIMENSIONAL IMAGING;

AMINO ACID SEQUENCE; APOPTOSIS REGULATORY PROTEINS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BCL-ASSOCIATED DEATH PROTEIN; BCL-X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARRIER PROTEINS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; ONCOGENE PROTEINS; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SEQUENCE ALIGNMENT; VIRAL PROTEINS;

BACTERIA (MICROORGANISMS); HUMAN HERPESVIRUS 8;

EID: 1442310957     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2003.08.012     Document Type: Review

References (44)

1. Thompson C.B. Science. 267:1995;1456-1462.
2. Reed J.C. Am. J. Pathol. 157:2000;1415-1430.
3. Fesik S.W. Cell. 103:2000;273-282.
4. Strauss S.E., Sneller M., Lenardo M.J., Puck J.M., Strober W. Ann. Intern. Med. 130:1999;591-601.
5. Rutledge S.E., Chin J.W., Schepartz A. Curr. Opin. Chem. Biol. 6:2002;479-485.
6. Hanahan D., Weinberg R.A. Cell. 100:2000;57-70.
7. Adams J.M., Cory C.S. Science. 281:1998;1322-1325.
8. Chittenden T., Flemington C., Houghton A., Ebb R., Gallo G., Elangovan B., Chinnadurai G., Lutz R. EMBO J. 14:1995;5589-5596.
9. Letai A., Bassik M.C., Walensky L.D., Sorcinelli M.D., Weiler S., Korsmeyer S.J. Cancer Cell. 2:2002;183-192.
10. Green D.R., Reed J.C. Science. 281:1998;1309-1312.
11. Wolter K.G., Hsu Y.T., Smith C.L., Nechushtan A., Xi X.G., Youle R.J. J. Cell Biol. 139:1997;1281-1292.
12. Li H., Zhu H., Xu C.J., Yuan J. Cell. 94:1998;491-501.
13. Muchmore S.W., Sattler M., Liang H., Meadows R.P., Harlan J.E., Yoon H.S., Nettesheim D., Chang B.S., Thompson C.B., Wong S., Ng S.L., Fesik S.W. Nature. 381:1996;335-341.
14. Dramsi S., Scheid M.P., Maiti A., Hojabrpour P., Chen X., Schubert K., Goodlett D.R., Aebersold R., Duronio V. J. Biol. Chem. 277:2002;6399-6405.
15. Cheng E.H., Kirsch D.G., Clem R.J., Ravi R., Kastan M.B., Bedi A., Ueno K., Hardwick J.M. Science. 278:1997;1966-1968.
16. Sattler M., Liang H., Nettesheim D., Meadows R.P., Harlan J.E., Eberstadt M., Yoon H.S., Shuker S.B., Chang B.S., Minn A.J., Thompson C.B., Fesik S.W. Science. 275:1997;983-986.
17. Schendel S.L., Montal M., Reed J.C. Cell Death Differ. 5:1998;372-380.
18. Shimizu S., Narita M., Tsujimoto Y. Nature. 399:1999;483-487.
19. Shimizu S., Konishi A., Kodama T., Tsujimoto Y. Proc. Natl. Acad. Sci. U. S. A. 97:2000;3100-3105.
20. Losonczi J.A., Olejniczak E.T., Betz S.F., Harlan J.E., Mack J., Fesik S.W. Biochemistry. 39:2000;11024-11033.
21. Petros A.M., Medek A., Nettesheim D.G., Kim D.H., Yoon H.S., Swift K., Matayoshi E.D., Oltersdorf T., Fesik S.W. Proc. Natl. Acad. Sci. U. S. A. 98:2001;3012-3017.
22. Oltvai Z.N., Korsmeyer S.J. Cell. 79:1994;189-192.
23. Cheng E.H., Levine B., Boise L.H., Thompson C.B., Hardwick J.M. Nature. 379:1996;554-556.
24. Holinger E.P., Chittenden T., Lutz R.J. J. Biol. Chem. 274:1999;13298-13304.
25. Rudin C.M., Otterson G.A., Mauer A.M., Villalona-Calero M.A., Tomek R., Prange B., George C.M., Szeto L., Vokes E.E. J. Oncol. 13:2002;539-545.
26. Wang J.L., Liu D., Zhang Z.J., Shan S., Han X., Srinivasula S.M., Croce C.M., Alnemri E.S., Huang Z. Proc. Natl. Acad. Sci. U. S. A. 97:2000;7124-7129.
27. Enyedy I.J., Ling Y., Nacro K., Tomita Y., Wu X.H., Cao Y.Y., Guo R.B., Li B.H., Zhu X.F., Huang Y., Long Y.Q., Roller P.P., Yang D.J., Wang S.M. J. Med. Chem. 44:2001;4313-4324.
28. Degterev A., Lugovskoy A., Cardone M., Mulley B., Wagner G., Mitchison T., Yuan J. Nat. Cell Biol. 3:2001;173-182.
29. Lugovskoy A.A., Degterev A.I., Fahmy A.F., Zhou P., Gross J.D., Yuan J., Wagner G. J. Am. Chem. Soc. 124:2002;1234-1240.
30. Tzung S.P., Kim K.M., Basanez G., Giedt C.D., Simon J., Zimmerberg J., Zhang K.Y., Hockenbery D.M. Nat. Cell Biol. 3:2001;183-191.
31. Orner B.P., Ernst J.T., Hamilton A.D. J. Am. Chem. Soc. 123:2001;5382-5383.
32. Kutzki O., Park H.S., Ernst J.T., Orner B.P., Yin H., Hamilton A.D. J. Am. Chem. Soc. 124:2002;11838-11839.
33. Kelekar A., Chang B.S., Harlan J.E., Fesik S.W., Thompson C.B. Mol. Cell. Biol. 17:1997;7040-7046.
34. Ottilie S., Diaz J.L., Horne W., Chang J., Wang Y., Wilson G., Chang S., Weeks S., Fritz L.C., Oltersdorf T. J. Biol. Chem. 272:1997;30866-30872.
35. Petros A.M., Nettesheim D.G., Wang Y., Olejniczak E.T., Meadows R.P., Mack J., Swift K., Matayoshi E.D., Zhang H., Thompson C.B., Fesik S.W. Protein Sci. 9:2000;2528-2534.
36. Suzuki M., Youle R.J., Tjandra N. Cell. 103:2000;645-654.
37. Khaled A.R., Kim K., Hofmeister R., Muegge K., Durum S.K. Proc. Natl. Acad. Sci. U. S. A. 96:1999;14476-14481.
38. Denisov A.Y., Madiraju M.S.R., Chen G., Khadir A., Beauparlant P., Attardo G., Shore G.C., Gehring K. J. Biol. Chem. 278:2003;21124-21128.
39. Hinds M.G., Lackmann M., Skea G.L., Harrison P.J., Huang D.C., Day C.L. EMBO J. 22:2003;1497-1507.
40. Chou J.J., Li H., Salvesen G.S., Yuan J., Wagner G. Cell. 96:1999;615-624.
41. McDonnell J.M., Fushman D., Milliman C.L., Korsmeyer S.J., Cowburn D. Cell. 96:1999;625-634.
42. Hardwick J.M. Semin. Cell Dev. Biol. 9:1998;339-349.
43. Huang Q., Petros A.M., Virgin H.W., Fesik S.W., Olejniczak E.T. Proc. Natl. Acad. Sci. U. S. A. 99:2002;3428-3433.
44. Bellows D.S., Chau B.N., Lee P., Lazebnik Y., Burns W.H., Hardwick J.M. J. Virol. 74:2000;5024-5031.