Intracellular redox state as target for anti-influenza therapy: Are antioxidants always effective?

Current Topics in Medicinal Chemistry

Volumn 14, Issue 22, 2014, Pages 2529-2541

  Sgarbanti, Rossella ^a   Amatore, Donatella ^b,c   Celestino, Ignacio ^b,c   Marcocci, Maria Elena ^c   Fraternale, Alessandra ^d   Ciriolo, Maria Rosa ^a,e   Magnani, Mauro ^d   Saladino, Raffaele ^f   Garaci, Enrico ^a   Palamara, Anna Teresa ^a,c   Nencioni, Lucia ^c  

^a IRCCS SAN RAFFAELE PISANA   (Italy)

^b CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d UNIVERSITY OF URBINO   (Italy)

^e UNIVERSITY OF ROME TOR VERGATA   (Italy)

^f UNIVERSITY OF TUSCIA   (Italy)

Author keywords

Anti influenza therapy; Antioxidants; Antivirals; Influenza virus; Oxidative stress; Redox state

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CASPASE; CURCUMIN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUTATHIONE; HYDROXYTYROSOL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; OSELTAMIVIR; PEPTIDES AND PROTEINS; POLYPHENOL; PRODRUG; PROTEIN DISULFIDE ISOMERASE; PROTEIN SKQ1; PYRROLIDINE DITHIOCARBAMATE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RESVERATROL; RIBAVIRIN; RIMANTADINE; SUPEROXIDE DISMUTASE; THIOL; TROLOX C; UNCLASSIFIED DRUG; XANTHINE OXIDASE; ANTIVIRUS AGENT;

ANTIOXIDANT ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; AVIAN INFLUENZA; HUMAN; INFLUENZA; INFLUENZA A (H1N1); LIPID PEROXIDATION; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRION; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; VIRUS ASSEMBLY; VIRUS CELL INTERACTION; VIRUS INHIBITION; VIRUS REPLICATION; DRUG EFFECTS; INFLUENZA, HUMAN; OXIDATION REDUCTION REACTION;

ANTIOXIDANTS; ANTIVIRAL AGENTS; HUMANS; INFLUENZA, HUMAN; OXIDATION-REDUCTION;

EID: 84921857130     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/1568026614666141203125211     Document Type: Article

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