Vitamin E supplementation decreases lung virus titers in mice infected with influenza

Journal of Infectious Diseases

Volumn 176, Issue 1, 1997, Pages 273-276

  Hayek, Michael G ^b   Taylor, Scott F ^c   Bender, Bradley S ^c   Han, Sung Nim ^c   Meydani, Mohsen ^c   Smith, Donald E ^c   Eghtesada, Shahriar ^c   Meydani, Simin Nikbin ^a  

^a TUFTS UNIVERSITY   (United States)

^b IAMS COMPANY   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; VIRUS HEMAGGLUTININ;

ADOLESCENT; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DIET SUPPLEMENTATION; HEMAGGLUTINATION INHIBITION; INFLUENZA; INFLUENZA VIRUS; INOCULATION; LUNG ALVEOLUS CELL; LUNG INFECTION; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; VIRUS HEMAGGLUTINATION; VIRUS TITRATION; VITAMIN INTAKE;

EID: 0030905373     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/517265     Document Type: Article

References (17)

1. Yoshikawa TT. Impact of aging on host to infectious disease. In: Geriatric clinical pharmacology. Wood WG, Strong R, eds. Raven Press, 1987:107-13.
2. Bender BS, Small PA. Influenza: pathogenesis and host defense. Semin Respir Infect 1992;7:38-45.
3. Hennet T, Peterhans E, Stocker R. Alterations in antioxidant defenses in lung and liver of mice infected with influenza A virus. J Gen Virol 1992;73:39-46.
4. Meydani SN, Hayek M. Vitamin E and immune response. In: Chandra RK, ed. Proceedings of the International Congress on Nutrition and Immunity. St. Johns, Canada: ARTS Biomedical Publishers and Distributors, 1992:105-28.
5. Hennet T, Ziltener HT, Frei K, Peterhans E. A kinetic study of immune mediators in the lungs of mice infected with influenza A virus. J Immunol 1992;149:932-9.
6. 2 synthesis and enhances the immune response of aged mice. Mech Ageing Dev 1986;34:191-201.
7. Meydani SN, Barklund MP, Liu S, et al. Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects. Am J Clin Nutr 1990;52:557-63.
8. Meydani SN, Stocking LM, Shapiro AC, Meydani M, Blumberg JB. Fish oil- and tocophcrol-induced changes in ex vivo synthesis of spleen and lung leukotriene B4 (LTB4) in mice. Ann NY Acad Sci 1988;524:395-7.
9. Bender BS, Johnson MP, Small PA. Influenza in senescent mice: impaired cytotoxic T-lymphocyte activity is correlated with prolonged infection. Immunology 1991;72:514-9.
10. Bender BS, Small PA. Heterotypic immune mice lose protection against influenza virus infection with senescence. J Infect Dis 1993;168:873-80.
11. Stein-Streilein J, Guffee J. In vivo treatment of mice and hamsters with antibodies to asialo GM1 increases morbidity and mortality to pulmonary influenza infection. J Immunol 1986;136:1435-41.
12. Salk JE. Simplified procedure for titrating hemagglutinating capacity of influenza virus and the corresponding antibody. J Immunol 1944;49:87-98.
13. Effros RB, Walford RL, Weindruch R, Mitcheltree C. Influences of dietary restriction on immunity to influenza in aged mice. J Gerontol 1991;46:B142-7.
14. Shigenaga MK, Ames BN. Oxidants and mitochondrial decay in aging. In: Frei B, ed. Natural antioxidants in human health and disease. New York, NY: Academic Press, 1994:84-8.
15. 2 generation by xanthine oxidase of pathogenesis of influenza virus infection in mice. J Clin Invest 1990;85:739-45.
16. Pahl HL, Baeuerle PA. Expression of influenza virus hemagglutinin activates transcription factor NF-κB. J Virol 1995;69:1480-4.
17. Cannon JG, Meydani SN, Fielding RA, et al. Acute phase response in exercise. II. Associations between vitamin E, cytokines, and muscle proteolysis. Am J Physiol 1991;260:R1235-40.