메뉴 건너뛰기




Volumn 84, Issue 1, 1996, Pages 7-12

N-acetylcysteine increases the glutathione content and protects rat alveolar type II cells against paraquat-induced cytotoxicity

Author keywords

Alveolar type II cells; Cytotoxicity; Glutathione; N acetylcysteine; Paraquat

Indexed keywords

ACETYLCYSTEINE; GLUTATHIONE; PARAQUAT;

EID: 0030071905     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-4274(95)03446-3     Document Type: Article
Times cited : (70)

References (24)
  • 1
    • 0017251538 scopus 로고
    • Paraquat accumulation: Tissue and species specificity
    • Rose, M.S., Lock, E.A., Smith, L.L. and Wyatt, I. (1976) Paraquat accumulation: tissue and species specificity. Biochem. Pharmacol. 25, 419-423.
    • (1976) Biochem. Pharmacol. , vol.25 , pp. 419-423
    • Rose, M.S.1    Lock, E.A.2    Smith, L.L.3    Wyatt, I.4
  • 2
    • 0019194294 scopus 로고
    • Tissue and cellular disposition of paraquat in mice
    • Waddell, W.J. and Marlowe, C. (1980) Tissue and cellular disposition of paraquat in mice. Toxicol. Appl. Pharmacol. 56, 127-140.
    • (1980) Toxicol. Appl. Pharmacol. , vol.56 , pp. 127-140
    • Waddell, W.J.1    Marlowe, C.2
  • 3
    • 0023905539 scopus 로고
    • The accumulation and localisation of putrescine, spermidine, spermine and paraquat in the rat lung
    • Wyatt, I., Soames, A.R., Clay, M.F. and Smith, L.L. (1988) The accumulation and localisation of putrescine, spermidine, spermine and paraquat in the rat lung. Biochem. Pharmacol. 37, 1909-1918.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 1909-1918
    • Wyatt, I.1    Soames, A.R.2    Clay, M.F.3    Smith, L.L.4
  • 4
    • 0015821035 scopus 로고
    • Bipyridilium quaternary salts and related compounds; pulse radiolysis studies and the reaction of paraquat radicals with oxygen, implications for the mode of action of bipyridilium herbicides
    • Farrington, J.A., Ebert, M., Land, E.Y. and Fletcher, K. (1973) Bipyridilium quaternary salts and related compounds; pulse radiolysis studies and the reaction of paraquat radicals with oxygen, implications for the mode of action of bipyridilium herbicides. Biochem. Biophys. Acta 314, 372-381.
    • (1973) Biochem. Biophys. Acta , vol.314 , pp. 372-381
    • Farrington, J.A.1    Ebert, M.2    Land, E.Y.3    Fletcher, K.4
  • 6
    • 0021996122 scopus 로고
    • Oxidant lung injury: Intervention with sulfhydryl reagents
    • Patterson, G.E., Butler, J.A., Byrne, F.D. and Rhodes, M.I. (1985) Oxidant lung injury: Intervention with sulfhydryl reagents. Lung 163, 23-32.
    • (1985) Lung , vol.163 , pp. 23-32
    • Patterson, G.E.1    Butler, J.A.2    Byrne, F.D.3    Rhodes, M.I.4
  • 9
    • 0022527271 scopus 로고
    • An improved method for isolating type II cells in high yield and purity
    • Dobbs, L.G., Gonzalez, R. and Williams, M.G. (1986) An improved method for isolating type II cells in high yield and purity. Am. Rev. Respir. Dis. 134, 141-145.
    • (1986) Am. Rev. Respir. Dis. , vol.134 , pp. 141-145
    • Dobbs, L.G.1    Gonzalez, R.2    Williams, M.G.3
  • 10
    • 0014481378 scopus 로고
    • Enzymatic method for quantification of nanogram amounts of total and oxidized glutathione
    • Tietze, F. (1969) Enzymatic method for quantification of nanogram amounts of total and oxidized glutathione. Anal. Biochem. 27, 502-522.
    • (1969) Anal. Biochem. , vol.27 , pp. 502-522
    • Tietze, F.1
  • 11
    • 0019740345 scopus 로고
    • Assay of glutathione, glutathione disulfide and glutathione mixed disulfides in biological samples
    • Ackerboom, T.P.M. and Sies, H. (1981) Assay of glutathione, glutathione disulfide and glutathione mixed disulfides in biological samples. Methods Enzymol. 77, 373-382.
    • (1981) Methods Enzymol. , vol.77 , pp. 373-382
    • Ackerboom, T.P.M.1    Sies, H.2
  • 13
    • 0026663152 scopus 로고
    • Competition between paraquat and putrescine for uptake by suspension of rat alveolar type II cells
    • Ghen, N., Bowles, M.R. and Pond, S. (1992). Competition between paraquat and putrescine for uptake by suspension of rat alveolar type II cells. Biochem. Pharmacol. 44, 1029-1036.
    • (1992) Biochem. Pharmacol. , vol.44 , pp. 1029-1036
    • Ghen, N.1    Bowles, M.R.2    Pond, S.3
  • 14
    • 0021266268 scopus 로고
    • Paraquat-induced injury of type II alveolar cells
    • Skillrud, D.M. and Martin, W.J. (1984) Paraquat-induced injury of type II alveolar cells. Am. Rev. Respir. Dis. 129, 995-999.
    • (1984) Am. Rev. Respir. Dis. , vol.129 , pp. 995-999
    • Skillrud, D.M.1    Martin, W.J.2
  • 15
    • 0026560909 scopus 로고
    • Glutathione protection in alveolar type II cells from fetal and neonatal rabbits
    • Brown, L.A., Bai, G. and Jones, D. (1992) Glutathione protection in alveolar type II cells from fetal and neonatal rabbits. Am. J. Physiol. 262, L305-L312.
    • (1992) Am. J. Physiol. , vol.262
    • Brown, L.A.1    Bai, G.2    Jones, D.3
  • 16
    • 0028293052 scopus 로고
    • Induction of intracellular glutathione in alveolar type II pneumocytes following BCNU exposure
    • Jenkinson, S.G., Lawrence, R.A., Zamora, G.A., Deneke, S.M. (1994) Induction of intracellular glutathione in alveolar type II pneumocytes following BCNU exposure. Am. J. Physiol. 266, L125-L130.
    • (1994) Am. J. Physiol. , vol.266
    • Jenkinson, S.G.1    Lawrence, R.A.2    Zamora, G.A.3    Deneke, S.M.4
  • 17
    • 0023860819 scopus 로고
    • Promotion of cystine uptake and its utilisation for glutathione biosynthesis induced by cysteamine and N-acetylcysteine
    • Issels, R.D., Nagele, A., Eckert, K.-G. and Wilmanns, W. (1988) Promotion of cystine uptake and its utilisation for glutathione biosynthesis induced by cysteamine and N-acetylcysteine. Biochem. Pharmacol. 37, 881-888.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 881-888
    • Issels, R.D.1    Nagele, A.2    Eckert, K.-G.3    Wilmanns, W.4
  • 18
    • 0026914862 scopus 로고
    • Elevation of glutathione levels in bovine pulmonary artery endothelial cells by NAC
    • Phelps, D.T., Deneke, S.M., Daley, D.L. and Fanburg, B.L. (1992) Elevation of glutathione levels in bovine pulmonary artery endothelial cells by NAC. Am. J. Respir. Cell Mol. Biol. 7, 293-299.
    • (1992) Am. J. Respir. Cell Mol. Biol. , vol.7 , pp. 293-299
    • Phelps, D.T.1    Deneke, S.M.2    Daley, D.L.3    Fanburg, B.L.4
  • 19
    • 0022896389 scopus 로고
    • Protection against paraquat-induced injury by exogenous gsh in pulmonary alveolar type II cells
    • Hagen, T.M., Brown, L.A. and Jones, D.P. (1986) Protection against paraquat-induced injury by exogenous GSH in pulmonary alveolar type II cells. Toxicol. Appl. Pharmacol. 35, 4537-4542.
    • (1986) Toxicol. Appl. Pharmacol. , vol.35 , pp. 4537-4542
    • Hagen, T.M.1    Brown, L.A.2    Jones, D.P.3
  • 20
    • 0025844980 scopus 로고
    • Molecular features necessary for the uptake of diamines and related compounds by the polyamine receptor of rat lung slices
    • O'Sullivan, M.C., Golding, B.T., Smith, L.L. and Wyatt I. (1991) Molecular features necessary for the uptake of diamines and related compounds by the polyamine receptor of rat lung slices. Biochem. Pharmacol. 41, 1839-1848.
    • (1991) Biochem. Pharmacol. , vol.41 , pp. 1839-1848
    • O'Sullivan, M.C.1    Golding, B.T.2    Smith, L.L.3    Wyatt, I.4
  • 21
    • 0025875051 scopus 로고
    • The metabolism of N-acetylcysteine by human endothelial cells
    • Cotgreave, I., Moldeus, P. and Schuppe, I. (1991) The metabolism of N-acetylcysteine by human endothelial cells. Biochem. Pharmacol. 42, 13-16.
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 13-16
    • Cotgreave, I.1    Moldeus, P.2    Schuppe, I.3
  • 22
    • 0027420576 scopus 로고
    • Biochemical manipulation of intracellular glutathione levels influence cytotoxocity to isolated human lymphocytes by sulfur mustard
    • Gross, C.L., Innace, J.K., Hovatter, R.C., Meier, H.L. and Smith, W.J. (1993) Biochemical manipulation of intracellular glutathione levels influence cytotoxocity to isolated human lymphocytes by sulfur mustard. Cell Biol. Toxicol. 9, 259-268.
    • (1993) Cell Biol. Toxicol. , vol.9 , pp. 259-268
    • Gross, C.L.1    Innace, J.K.2    Hovatter, R.C.3    Meier, H.L.4    Smith, W.J.5
  • 24
    • 0024432603 scopus 로고
    • Regulation of cellular glutathione
    • Deneke, S.M. and Fanburg, B.L. (1989) Regulation of cellular glutathione. Am. J. Physiol. 257, L163-L173.
    • (1989) Am. J. Physiol. , vol.257
    • Deneke, S.M.1    Fanburg, B.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.