N-acetyl-L-cysteine (NAC) inhibit mucin synthesis and pro-inflammatory mediators in alveolar type II epithelial cells infected with influenza virus A and B and with respiratory syncytial virus (RSV)

Biochemical Pharmacology

Volumn 82, Issue 5, 2011, Pages 548-555

  Mata, Manuel ^a,b,c   Morcillo, Esteban ^b,c   Gimeno, Concepcion ^c,d   Cortijo, Julio ^a,b,c  

^a HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSITY OF VALENCIA   (Spain)

^d University General Hospital of Valencia   (Spain)

Author keywords

COPD; Influenza; MUC5AC; NAC; RSV

Indexed keywords

ACETYLCYSTEINE; AUTACOID; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE P38; MUCIN 5AC; THIOL; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL NUCLEUS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME PHOSPHORYLATION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLUENZA A; INFLUENZA B; INFLUENZA VIRUS A; INFLUENZA VIRUS B; LUNG ALVEOLUS CELL TYPE 2; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY SYNCYTIAL VIRUS INFECTION; VIRUS INHIBITION; VIRUS REPLICATION;

ACETYLCYSTEINE; CELL LINE; HUMANS; INFLAMMATION MEDIATORS; INFLUENZA A VIRUS; INFLUENZA B VIRUS; MUCIN 5AC; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PULMONARY ALVEOLI; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY SYNCYTIAL VIRUSES; VIRUS REPLICATION;

EID: 79960928566     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.05.014     Document Type: Article

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