N-acetyl-l-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus

Biochemical Pharmacology

Volumn 79, Issue 3, 2010, Pages 413-420

  Geiler, Janina ^a   Michaelis, Martin ^a   Naczk, Patrizia ^a   Leutz, Anke ^a   Langer, Klaus ^b   Doerr, Hans Wilhelm ^a   Cinatl Jr , Jindrich ^a  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Apoptosis; Cytokines; H5N1; NAC; ROS

Indexed keywords

3 (4 TERT BUTYLPHENYLSULFONYL) 2 PROPENENITRILE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE P38; RANTES;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; CELL MIGRATION; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPATHOGENIC EFFECT; HUMAN; HUMAN CELL; INFLAMMATION; INFLUENZA VIRUS A H5N1; LUNG ALVEOLUS EPITHELIUM; MONOCYTE; MONOTHERAPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; VIRUS INHIBITION; VIRUS REPLICATION;

ACETYLCYSTEINE; ANIMALS; ANTIVIRAL AGENTS; CELL LINE, TUMOR; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; GENE EXPRESSION REGULATION, VIRAL; HUMANS; INFLAMMATION MEDIATORS; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA, HUMAN; VERO CELLS; VIRUS REPLICATION;

EID: 70450221927     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.08.025     Document Type: Article

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