Suppressing production of reactive oxygen species (ROS) for influenza A virus therapy

Trends in Pharmacological Sciences

Volumn 33, Issue 1, 2012, Pages 3-8

  Vlahos, Ross ^a   Stambas, John ^b,c   Selemidis, Stavros ^d  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b DEAKIN UNIVERSITY   (Australia)

^c CSIRO   (Australia)

^d MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; APOCYNIN; GAMMA INTERFERON; GLUTATHIONE PEROXIDASE; GP91DSAT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1; OSELTAMIVIR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SUPEROXIDE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZANAMIVIR;

APICAL MEMBRANE; CYTOKINE PRODUCTION; DRUG PROTEIN BINDING; ENZYME INHIBITION; ENZYME REPRESSION; HOMEOSTASIS; HOST RESISTANCE; HUMAN; IMMUNOMODULATION; INFECTION CONTROL; INFLUENZA A; LUNG ALVEOLUS MACROPHAGE; NONHUMAN; PATHOGENESIS; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN STABILITY; RESPIRATORY EPITHELIUM; REVIEW; TRANSGENE; UPREGULATION; VIRUS REPLICATION;

ANIMALS; HUMANS; INFLUENZA A VIRUS; INFLUENZA, HUMAN; NADPH OXIDASE; SUPEROXIDES;

EID: 84855779811     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2011.09.001     Document Type: Review

References (44)

1. P.C. Doherty Influenza and the challenge for immunology Nat. Immunol. 7 2006 449 455
2. World Health Organization (2009) Influenza (Seasonal) Fact Sheet (http://www.who.int/mediacentre/factsheets/fs211/en/)
3. N.A. Molinari The annual impact of seasonal influenza in the US: measuring disease burden and costs Vaccine 25 2007 5086 5096
4. M.T. Osterholm Preparing for the next pandemic N. Engl. J. Med. 352 2005 1839 1842 (Pubitemid 40627807)
5. A. Moscona Neuraminidase inhibitors for influenza N. Engl. J. Med. 353 2005 1363 1373 (Pubitemid 41362704)
6. A. Moscona Medical management of influenza infection Annu. Rev. Med. 59 2008 397 413 (Pubitemid 351287945)
7. B.J. Zheng Delayed antiviral plus immunomodulator treatment still reduces mortality in mice infected by high inoculum of influenza A/H5N1 virus Proc. Natl. Acad. Sci. U.S.A. 105 2008 8091 8096
8. A. Moscona Oseltamivir resistance - disabling our influenza defenses N. Engl. J. Med. 353 2005 2633 2636 (Pubitemid 41817709)
9. N.L. La Gruta A question of self-preservation: immunopathology in influenza virus infection Immunol. Cell Biol. 85 2007 85 92 (Pubitemid 46398724)
10. L.A. Perrone H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice PLoS Pathog. 4 2008 e1000115
11. T.M. Tumpey Characterization of the reconstructed 1918 Spanish influenza pandemic virus Science 310 2005 77 80 (Pubitemid 41434537)
12. T. Akaike Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals Proc. Natl. Acad. Sci. U.S.A. 93 1996 2448 2453 (Pubitemid 26104370)
13. Y. Imai Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury Cell 133 2008 235 249 (Pubitemid 351512299)
14. T. Oda Oxygen radicals in influenza-induced pathogenesis and treatment with pyran polymer-conjugated SOD Science 244 1989 974 976 (Pubitemid 19152287)
15. H.B. Suliman Prevention of influenza-induced lung injury in mice overexpressing extracellular superoxide dismutase Am. J. Physiol. Lung Cell. Mol. Physiol. 280 2001 L69 L78
16. C. Szabo Peroxynitrite: biochemistry, pathophysiology and development of therapeutics Nat. Rev. Drug Discov. 6 2007 662 680 (Pubitemid 47207751)
17. R. Vlahos Inhibition of Nox2 oxidase activity ameliorates influenza A virus-induced lung inflammation PLoS Pathog. 7 2011 e1001271
18. A. Lazrak Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species FASEB J. 23 2009 3829 3842
19. I. Rahman Oxidant and antioxidant balance in the airways and airway diseases Eur. J. Pharmacol. 533 2006 222 239 (Pubitemid 43340015)
20. Y. Takada Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase J. Biol. Chem. 278 2003 24233 24241 (Pubitemid 36830260)
21. I. Rahman Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: potential mechanism in gene transcription in lung inflammation Mol. Cell. Biochem. 234-235 2002 239 248 (Pubitemid 34777863)
22. R. Vlahos The anti-oxidant enzyme glutathione peroxidise-1 reduces influenza A virus-induced lung inflammation Am. J. Respir. Crit. Care Med. 183 2011 PA2754
23. M.A. Beck Selenium deficiency increases the pathology of an influenza virus infection FASEB J. 15 2001 1481 1483
24. L.P. Tantcheva Effect of vitamin E and vitamin C combination on experimental influenza virus infection Methods Find Exp. Clin. Pharmacol. 25 2003 259 264 (Pubitemid 36764626)
25. D. Ungheri Protective effect of n-acetylcysteine in a model of influenza infection in mice Int. J. Immunopathol. Pharmacol. 13 2000 123 128 (Pubitemid 32001492)
26. S. De Flora Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity with long-term N-acetylcysteine treatment Eur. Respir. J. 10 1997 1535 1541 (Pubitemid 27311068)
27. A. Garozzo N-acetylcysteine synergizes with oseltamivir in protecting mice from lethal influenza infection Int. J. Immunopathol. Pharmacol. 20 2007 349 354 (Pubitemid 47104855)
28. W. Dröge Free radicals in the physiological control of cell function Physiol. Rev. 82 2002 47 95 (Pubitemid 34654215)
29. S. Selemidis NADPH oxidases in the vasculature: molecular features, roles in disease and pharmacological inhibition Pharmacol. Ther. 120 2008 254 291
30. G.R. Drummond Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets Nat. Rev. Drug Discov. 10 2011 453 471
31. B. Griffith NOX enzymes and pulmonary disease Antioxid. Redox Signal. 11 2009 2505 2516
32. S. Carnesecchi NADPH oxidase-1 plays a crucial role in hyperoxia-induced acute lung injury in mice Am. J. Respir. Crit. Care Med. 180 2009 972 981
33. J. Tickner Nox2-derived ROS in PPARgamma signaling and cell-cycle progression of lung alveolar epithelial cells Free Radic. Biol. Med. 51 2011 763 772
34. A. Soucy-Faulkner Requirement of NOX2 and reactive oxygen species for efficient RIG-I-mediated antiviral response through regulation of MAVS expression PLoS Pathog. 6 2010 e1000930
35. K. Fink Dual role of NOX2 in respiratory syncytial virus- and sendai virus-induced activation of NF-kappaB in airway epithelial cells J. Immunol. 180 2008 6911 6922
36. Y. Takemura Rac1-mediated NADPH oxidase release of O2- regulates epithelial sodium channel activity in the alveolar epithelium Am. J. Physiol. Lung Cell. Mol. Physiol. 298 2010 L509 L520
37. E.L. Mills Initiation of the respiratory burst of human neutrophils by influenza virus Infect. Immun. 32 1981 1200 1205 (Pubitemid 11109829)
38. G.D. Buffinton Oxidative stress in lungs of mice infected with influenza A virus Free Radic. Res. Commun. 16 1992 99 110
39. R.J. Snelgrove An absence of reactive oxygen species improves the resolution of lung influenza infection Eur. J. Immunol. 36 2006 1364 1373 (Pubitemid 43942127)
40. S. Heumuller Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant Hypertension 51 2008 211 217 (Pubitemid 351159930)
41. J. Stefanska Apocynin decreases hydrogen peroxide and nitrate concentrations in exhaled breath in healthy subjects Pulm. Pharmacol. Ther. 23 2010 48 54
42. F.E. Rey Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice Circ. Res. 89 2001 408 414 (Pubitemid 34132656)
43. S.M. Holland Chronic granulomatous disease Clin. Rev. Allergy Immunol. 38 2010 3 10
44. D.B. Kuhns Residual NADPH oxidase and survival in chronic granulomatous disease N. Engl. J. Med. 363 2010 2600 2610