Elucidation of the interaction loci of the human pyruvate dehydrogenase complex e2·E3BP core with pyruvate dehydrogenase kinase 1 and kinase 2 by h/d exchange mass spectrometry and nuclear magnetic resonance

Biochemistry

Volumn 54, Issue 1, 2015, Pages 69-82

  Wang, Junjie ^a   Kumaran, Sowmini ^a   Zhou, Jieyu ^a   Nemeria, Natalia S ^a   Tao, Hu ^a   Kakalis, Lazaros ^a   Park, Yun Hee ^b   Birkaya, Barbara ^b   Patel, Mulchand S ^b   Jordan, Frank ^a  

^a RUTGERS UNIVERSITY   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ENZYMES; MASS SPECTROMETRY; PROTEINS; SPECTROMETRY;

BINDING PROTEINS; BINDING SPECIFICITIES; CATALYTIC COMPONENTS; INTERACTION MAPS; NUCLEAR MAGNETIC RESONANCE(NMR); PYRUVATE DEHYDROGENASE COMPLEX; PYRUVATE DEHYDROGENASE KINASE; SERINE PHOSPHORYLATION;

NUCLEAR MAGNETIC RESONANCE;

BINDING PROTEIN; DEUTERIUM; E2 BINDING PROTEIN; E3 BINDING PROTEIN; PYRUVATE DEHYDROGENASE COMPLEX; PYRUVATE DEHYDROGENASE KINASE; PYRUVATE DEHYDROGENASE KINASE 1; PYRUVATE DEHYDROGENASE KINASE 2; UNCLASSIFIED DRUG; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE;

ARTICLE; CHEMICAL BOND; COMPLEX FORMATION; CRYSTAL STRUCTURE; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; IONIC STRENGTH; ISOTHERMAL TITRATION CALORIMETRY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SEQUENCE ALIGNMENT; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; DEUTERIUM HYDROGEN EXCHANGE; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE; PHYSIOLOGY; PROCEDURES; PROTEIN SECONDARY STRUCTURE; RAT;

AMINO ACID SEQUENCE; ANIMALS; DEUTERIUM EXCHANGE MEASUREMENT; HUMANS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN-SERINE-THREONINE KINASES; RATS;

EID: 84921270898     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi5013113     Document Type: Article

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