-
1
-
-
20344396123
-
Eph receptor signalling casts a wide net on cell behaviour
-
Pasquale EB. 2005. Eph receptor signalling casts a wide net on cell behaviour. Nat. Rev. Mol. Cell Biol. 6:462-75
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 462-475
-
-
Pasquale, E.B.1
-
2
-
-
41149084179
-
Eph-ephrin bidirectional signaling in physiology and disease
-
Pasquale EB. 2008. Eph-ephrin bidirectional signaling in physiology and disease. Cell 133:38-52
-
(2008)
Cell
, vol.133
, pp. 38-52
-
-
Pasquale, E.B.1
-
3
-
-
84863907676
-
Molecular mechanisms of cell segregation and boundary formation in development and tumorigenesis
-
Batlle E, Wilkinson DG. 2012. Molecular mechanisms of cell segregation and boundary formation in development and tumorigenesis. Cold Spring Harb. Perspect. Biol. 4:a008227
-
(2012)
Cold Spring Harb. Perspect. Biol.
, vol.4
, pp. a008227
-
-
Batlle, E.1
Wilkinson, D.G.2
-
4
-
-
77649114060
-
Eph receptors and ephrins in cancer: Bidirectional signalling and beyond
-
Pasquale EB. 2010. Eph receptors and ephrins in cancer: bidirectional signalling and beyond. Nat. Rev. Cancer 10:165-80
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 165-180
-
-
Pasquale, E.B.1
-
5
-
-
33747891298
-
Roles of Eph receptors and ephrins in the normal and damaged adult CNS
-
Goldshmit Y, McLenachan S, Turnley A. 2006. Roles of Eph receptors and ephrins in the normal and damaged adult CNS. Brain Res. Rev. 52:327-45
-
(2006)
Brain Res. Rev.
, vol.52
, pp. 327-345
-
-
Goldshmit, Y.1
McLenachan, S.2
Turnley, A.3
-
6
-
-
84863925294
-
Regulation and misregulation of Eph/ephrin expression
-
Arvanitis DN, Davy A. 2012. Regulation and misregulation of Eph/ephrin expression. Cell Adhes. Migr. 6:131-37
-
(2012)
Cell Adhes. Migr.
, vol.6
, pp. 131-137
-
-
Arvanitis, D.N.1
Davy, A.2
-
7
-
-
84877626308
-
EphA2 cleavage by MT1- MMP triggers single cancer cell invasion via homotypic cell repulsion
-
Sugiyama N, Gucciardo E, Tatti O, Varjosalo M, Hyytiainen M, et al. 2013. EphA2 cleavage by MT1- MMP triggers single cancer cell invasion via homotypic cell repulsion. J. Cell Biol. 201:467-84
-
(2013)
J. Cell Biol.
, vol.201
, pp. 467-484
-
-
Sugiyama, N.1
Gucciardo, E.2
Tatti, O.3
Varjosalo, M.4
Hyytiainen, M.5
-
9
-
-
78349252732
-
Eph/ephrinmolecules- A hub for signaling and endocytosis
-
Pitulescu ME, Adams RH. 2010. Eph/ephrinmolecules- A hub for signaling and endocytosis. Genes Dev. 24:2480-92
-
(2010)
Genes Dev.
, vol.24
, pp. 2480-2492
-
-
Pitulescu, M.E.1
Adams, R.H.2
-
10
-
-
84870853546
-
The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas
-
Binda E, Visioli A, Giani F, Lamorte G, Copetti M, et al. 2012. The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas. Cancer Cell 22:765-80
-
(2012)
Cancer Cell
, vol.22
, pp. 765-780
-
-
Binda, E.1
Visioli, A.2
Giani, F.3
Lamorte, G.4
Copetti, M.5
-
11
-
-
84874895637
-
The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1
-
Hwang YS, Lee HS, Kamata T, Mood K, Cho HJ, et al. 2013. The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1. Genes Dev. 27:491-503
-
(2013)
Genes Dev.
, vol.27
, pp. 491-503
-
-
Hwang, Y.S.1
Lee, H.S.2
Kamata, T.3
Mood, K.4
Cho, H.J.5
-
12
-
-
84873363217
-
Efficient siRNA delivery into tumor cells by p19-YSA fusion protein
-
Choi KM, Park GL, Hwang KY, Lee JW, Ahn HJ. 2013. Efficient siRNA delivery into tumor cells by p19-YSA fusion protein. Mol. Pharm. 10:763-73
-
(2013)
Mol. Pharm.
, vol.10
, pp. 763-773
-
-
Choi, K.M.1
Park, G.L.2
Hwang, K.Y.3
Lee, J.W.4
Ahn, H.J.5
-
13
-
-
84857442761
-
Non-SH2/PDZ reverse signaling by ephrins
-
Daar IO. 2012. Non-SH2/PDZ reverse signaling by ephrins. Semin. Cell Dev. Biol. 23:65-74
-
(2012)
Semin. Cell Dev. Biol.
, vol.23
, pp. 65-74
-
-
Daar, I.O.1
-
14
-
-
57749121465
-
The EphA2 receptor and ephrinA1 ligand in solid tumors: Function and therapeutic targeting
-
Wykosky J, Debinski W. 2008. The EphA2 receptor and ephrinA1 ligand in solid tumors: function and therapeutic targeting. Mol. Cancer Res. 6:1795-806
-
(2008)
Mol. Cancer Res.
, vol.6
, pp. 1795-1806
-
-
Wykosky, J.1
Debinski, W.2
-
15
-
-
84865109690
-
EphrinA1 is released in three forms from cancer cells by matrix metalloproteases
-
Beauchamp A, Lively MO, Mintz A, Gibo D, Wykosky J, Debinski W. 2012. EphrinA1 is released in three forms from cancer cells by matrix metalloproteases. Mol. Cell. Biol. 32:3253-64
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 3253-3264
-
-
Beauchamp, A.1
Lively, M.O.2
Mintz, A.3
Gibo, D.4
Wykosky, J.5
Debinski, W.6
-
16
-
-
84896715497
-
Attenuation of Eph receptor kinase activation in cancer cells by coexpressed ephrin ligands
-
Falivelli G, Lisabeth EM, Rubio de la Torre E, Perez-Tenorio G, Tosato G, et al. 2013. Attenuation of Eph receptor kinase activation in cancer cells by coexpressed ephrin ligands. PLOS ONE 8:e81445
-
(2013)
Plos One
, vol.8
, pp. e81445
-
-
Falivelli, G.1
Lisabeth, E.M.2
Rubio De La Torre, E.3
Perez-Tenorio, G.4
Tosato, G.5
-
18
-
-
79953756867
-
Dancingwith the dead: Eph receptors and their kinase-null partners
-
Truitt L, Freywald A. 2011. Dancingwith the dead: Eph receptors and their kinase-null partners. Biochem. Cell Biol. 89:115-29
-
(2011)
Biochem. Cell Biol.
, vol.89
, pp. 115-129
-
-
Truitt, L.1
Freywald, A.2
-
19
-
-
79952433556
-
A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion
-
Gopal U, Bohonowych JE, Lema-Tome C, Liu A, Garrett-Mayer E, et al. 2011. A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion. PLOS ONE 6:e17649
-
(2011)
Plos One
, vol.6
, pp. e17649
-
-
Gopal, U.1
Bohonowych, J.E.2
Lema-Tome, C.3
Liu, A.4
Garrett-Mayer, E.5
-
20
-
-
78751496279
-
Proteomic snapshot of the EGFinduced ubiquitin network
-
Argenzio E, Bange T, Oldrini B, Bianchi F, Peesari R, et al. 2011. Proteomic snapshot of the EGFinduced ubiquitin network. Mol. Syst. Biol. 7:462
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 462
-
-
Argenzio, E.1
Bange, T.2
Oldrini, B.3
Bianchi, F.4
Peesari, R.5
-
21
-
-
84876418302
-
Reelin induces EphB activation
-
Bouche E, Romero-Ortega MI, Henkemeyer M, Catchpole T, Leemhuis J, et al. 2013. Reelin induces EphB activation. Cell Res. 23:473-90
-
(2013)
Cell Res.
, vol.23
, pp. 473-490
-
-
Bouche, E.1
Romero-Ortega, M.I.2
Henkemeyer, M.3
Catchpole, T.4
Leemhuis, J.5
-
22
-
-
67649361516
-
EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt
-
Miao H, Li DQ, Mukherjee A, Guo H, Petty A, et al. 2009. EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt. Cancer Cell 16:9-20
-
(2009)
Cancer Cell
, vol.16
, pp. 9-20
-
-
Miao, H.1
Li, D.Q.2
Mukherjee, A.3
Guo, H.4
Petty, A.5
-
23
-
-
78649883292
-
Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells
-
Astin JW, Batson J, Kadir S, Charlet J, Persad RA, et al. 2010. Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells. Nat. Cell Biol. 12:1194-204
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 1194-1204
-
-
Astin, J.W.1
Batson, J.2
Kadir, S.3
Charlet, J.4
Persad, R.A.5
-
24
-
-
84901008799
-
EphrinB3 blocks EphB3 dependence receptor functions to prevent cell death following traumatic brain injury
-
Theus MH, Ricard J, Glass SJ, Travieso LG, Liebl DJ. 2014. EphrinB3 blocks EphB3 dependence receptor functions to prevent cell death following traumatic brain injury. Cell Death Dis. 5:e1207
-
(2014)
Cell Death Dis.
, vol.5
, pp. e1207
-
-
Theus, M.H.1
Ricard, J.2
Glass, S.J.3
Travieso, L.G.4
Liebl, D.J.5
-
25
-
-
77951200415
-
Ephrin-B2 regulates endothelial cell morphology and motility independently of Eph-receptor binding
-
Bochenek ML, Dickinson S, Astin JW, Adams RH, Nobes CD. 2010. Ephrin-B2 regulates endothelial cell morphology and motility independently of Eph-receptor binding. J. Cell Sci. 123:1235-46
-
(2010)
J. Cell Sci.
, vol.123
, pp. 1235-1246
-
-
Bochenek, M.L.1
Dickinson, S.2
Astin, J.W.3
Adams, R.H.4
Nobes, C.D.5
-
26
-
-
79955467998
-
Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration
-
Senturk A, Pfennig S, Weiss A, Burk K, Acker-Palmer A. 2011. Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration. Nature 472:356-60
-
(2011)
Nature
, vol.472
, pp. 356-360
-
-
Senturk, A.1
Pfennig, S.2
Weiss, A.3
Burk, K.4
Acker-Palmer, A.5
-
27
-
-
84857911170
-
Ephrin-B1 is a novel specific component of the lateral membrane of the cardiomyocyte and is essential for the stability of cardiac tissue architecture cohesion
-
Genet G, Guilbeau-Frugier C, Honton B, Dague E, Schneider MD, et al. 2012. Ephrin-B1 is a novel specific component of the lateral membrane of the cardiomyocyte and is essential for the stability of cardiac tissue architecture cohesion. Circ. Res. 110:688-700
-
(2012)
Circ. Res.
, vol.110
, pp. 688-700
-
-
Genet, G.1
Guilbeau-Frugier, C.2
Honton, B.3
Dague, E.4
Schneider, M.D.5
-
28
-
-
39449085234
-
Eph/ephrin signaling: Networks
-
Arvanitis D, Davy A. 2008. Eph/ephrin signaling: networks. Genes Dev. 22:416-29
-
(2008)
Genes Dev.
, vol.22
, pp. 416-429
-
-
Arvanitis, D.1
Davy, A.2
-
29
-
-
84859633874
-
Ephrin regulation of synapse formation, function and plasticity
-
Hruska M, Dalva MB. 2012. Ephrin regulation of synapse formation, function and plasticity. Mol. Cell Neurosci. 50:35-44
-
(2012)
Mol. Cell Neurosci.
, vol.50
, pp. 35-44
-
-
Hruska, M.1
Dalva, M.B.2
-
32
-
-
84870890723
-
Ephs and ephrins resurface in inflammation, immunity, and atherosclerosis
-
Funk SD, Orr AW. 2013. Ephs and ephrins resurface in inflammation, immunity, and atherosclerosis. Pharmacol. Res. 67:42-52
-
(2013)
Pharmacol. Res.
, vol.67
, pp. 42-52
-
-
Funk, S.D.1
Orr, A.W.2
-
33
-
-
84868106303
-
Eph/ephrin signaling in injury and inflammation
-
Coulthard MG, Morgan M, Woodruff TM, Arumugam TV, Taylor SM, et al. 2012. Eph/ephrin signaling in injury and inflammation. Am. J. Pathol. 181:1493-503
-
(2012)
Am. J. Pathol.
, vol.181
, pp. 1493-1503
-
-
Coulthard, M.G.1
Morgan, M.2
Woodruff, T.M.3
Arumugam, T.V.4
Taylor, S.M.5
-
34
-
-
84860388355
-
EphBs: An integral link between synaptic function and synaptopathies
-
Sheffler-Collins SI, Dalva MB. 2012. EphBs: an integral link between synaptic function and synaptopathies. Trends Neurosci. 35:293-304
-
(2012)
Trends Neurosci.
, vol.35
, pp. 293-304
-
-
Sheffler-Collins, S.I.1
Dalva, M.B.2
-
35
-
-
84855610801
-
Eph receptors at synapses: Implications in neurodegenerative diseases
-
Chen Y, Fu AK, Ip NY. 2012. Eph receptors at synapses: implications in neurodegenerative diseases. Cell Signal. 24:606-11
-
(2012)
Cell Signal.
, vol.24
, pp. 606-611
-
-
Chen, Y.1
Fu, A.K.2
Ip, N.Y.3
-
36
-
-
84857442694
-
Targeting Eph receptors with peptides and small molecules: Progress and challenges
-
Noberini R, Lamberto I, Pasquale EB. 2012. Targeting Eph receptors with peptides and small molecules: progress and challenges. Semin. Cell Dev. Biol. 23:51-57
-
(2012)
Semin. Cell Dev. Biol.
, vol.23
, pp. 51-57
-
-
Noberini, R.1
Lamberto, I.2
Pasquale, E.B.3
-
37
-
-
84901497370
-
Therapeutic perspectives of Eph-ephrin system modulation
-
Tognolini M, Hassan-Mohamed I, Giorgio C, Zanotti I, Lodola A. 2013. Therapeutic perspectives of Eph-ephrin system modulation. Drug Discov. Today 19:661-69
-
(2013)
Drug Discov. Today
, vol.19
, pp. 661-669
-
-
Tognolini, M.1
Hassan-Mohamed, I.2
Giorgio, C.3
Zanotti, I.4
Lodola, A.5
-
38
-
-
84894532247
-
Patents related to EPH receptors and ligands
-
Harrison C. 2014. Patents related to EPH receptors and ligands. Nat. Rev. Drug Discov. 13:13
-
(2014)
Nat. Rev. Drug Discov.
, vol.13
, pp. 13
-
-
Harrison, C.1
-
40
-
-
84888317019
-
Multivalent ligands control stem cell behaviour in vitro and in vivo
-
Conway A, Vazin T, Spelke DP, Rode NA, Healy KE, et al. 2013. Multivalent ligands control stem cell behaviour in vitro and in vivo. Nat. Nanotechnol. 8:831-38
-
(2013)
Nat. Nanotechnol.
, vol.8
, pp. 831-838
-
-
Conway, A.1
Vazin, T.2
Spelke, D.P.3
Rode, N.A.4
Healy, K.E.5
-
41
-
-
80052774673
-
EphA4 blockers promote axonal regeneration and functional recovery following spinal cord injury in mice
-
Goldshmit Y, Spanevello MD, Tajouri S, Li L, Rogers F, et al. 2011. EphA4 blockers promote axonal regeneration and functional recovery following spinal cord injury in mice. PLOS ONE 6:e24636
-
(2011)
Plos One
, vol.6
, pp. e24636
-
-
Goldshmit, Y.1
Spanevello, M.D.2
Tajouri, S.3
Li, L.4
Rogers, F.5
-
42
-
-
35949001327
-
Regeneration-enhancing effects of EphA4 blocking peptide following corticospinal tract injury in adult rat spinal cord
-
Fabes J, Anderson P, Brennan C, Bolsover S. 2007. Regeneration-enhancing effects of EphA4 blocking peptide following corticospinal tract injury in adult rat spinal cord. Eur. J. Neurosci. 26:2496-505
-
(2007)
Eur. J. Neurosci.
, vol.26
, pp. 2496-2505
-
-
Fabes, J.1
Anderson, P.2
Brennan, C.3
Bolsover, S.4
-
43
-
-
84879330761
-
Acute delivery of EphA4-Fc improves functional recovery after contusive spinal cord injury in rats
-
Spanevello MD, Tajouri SI, Mirciov C, Kurniawan N, Pearse MJ, et al. 2013. Acute delivery of EphA4-Fc improves functional recovery after contusive spinal cord injury in rats. J. Neurotrauma 30:1023-34
-
(2013)
J. Neurotrauma
, vol.30
, pp. 1023-1034
-
-
Spanevello, M.D.1
Tajouri, S.I.2
Mirciov, C.3
Kurniawan, N.4
Pearse, M.J.5
-
44
-
-
84897035369
-
Upregulation of axon guidance molecules in the adult central nervous system of Nogo-A knockout mice restricts neuronal growth and regeneration
-
Kempf A, Montani L, Petrinovic MM, Schroeter A, Weinmann O, et al. 2013. Upregulation of axon guidance molecules in the adult central nervous system of Nogo-A knockout mice restricts neuronal growth and regeneration. Eur. J. Neurosci. 38:3567-79
-
(2013)
Eur. J. Neurosci.
, vol.38
, pp. 3567-3579
-
-
Kempf, A.1
Montani, L.2
Petrinovic, M.M.3
Schroeter, A.4
Weinmann, O.5
-
45
-
-
84861321551
-
Differential gene expression in the EphA4 knockout spinal cord and analysis of the inflammatory response following spinal cord injury
-
Munro KM, Perreau VM, Turnley AM. 2012. Differential gene expression in the EphA4 knockout spinal cord and analysis of the inflammatory response following spinal cord injury. PLOS ONE 7:e37635
-
(2012)
Plos One
, vol.7
, pp. e37635
-
-
Munro, K.M.1
Perreau, V.M.2
Turnley, A.M.3
-
46
-
-
84859469352
-
Myelin-derived ephrinB3 restricts axonal regeneration and recovery after adult CNS injury
-
Duffy P, Wang X, Siegel CS, Tu N, Henkemeyer M, et al. 2012. Myelin-derived ephrinB3 restricts axonal regeneration and recovery after adult CNS injury. Proc. Natl. Acad. Sci. USA 109:5063-68
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 5063-5068
-
-
Duffy, P.1
Wang, X.2
Siegel, C.S.3
Tu, N.4
Henkemeyer, M.5
-
47
-
-
84876440831
-
Improved axonal regeneration after spinal cord injury in mice with conditional deletion of ephrin B2 under the GFAP promoter
-
Ren Z, Chen X, Yang J, Kress BT, Tong J, et al. 2013. Improved axonal regeneration after spinal cord injury in mice with conditional deletion of ephrin B2 under the GFAP promoter. Neuroscience 241:89-99
-
(2013)
Neuroscience
, vol.241
, pp. 89-99
-
-
Ren, Z.1
Chen, X.2
Yang, J.3
Kress, B.T.4
Tong, J.5
-
48
-
-
84868656581
-
EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans
-
Van Hoecke A, Schoonaert L, Lemmens R, Timmers M, Staats KA, et al. 2012. EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans. Nat. Med. 18:1418-22
-
(2012)
Nat. Med.
, vol.18
, pp. 1418-1422
-
-
Van Hoecke, A.1
Schoonaert, L.2
Lemmens, R.3
Timmers, M.4
Staats, K.A.5
-
49
-
-
84865154517
-
A role for ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after stroke
-
Overman JJ, Clarkson AN, Wanner IB, Overman WT, Eckstein I, et al. 2012. A role for ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after stroke. Proc. Natl. Acad. Sci. USA 109:E2230-39
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. E2230-E2239
-
-
Overman, J.J.1
Clarkson, A.N.2
Wanner, I.B.3
Overman, W.T.4
Eckstein, I.5
-
50
-
-
84877906310
-
Modifying expression of EphA4 and its downstream targets improves functional recovery after stroke
-
Lemmens R, Jaspers T, Robberecht W, Thijs VN. 2013. Modifying expression of EphA4 and its downstream targets improves functional recovery after stroke. Hum. Mol. Genet. 22:2214-20
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 2214-2220
-
-
Lemmens, R.1
Jaspers, T.2
Robberecht, W.3
Thijs, V.N.4
-
51
-
-
78650970378
-
Reversing EphB2 depletion rescues cognitive functions in Alzheimer model
-
Cisse M, Halabisky B, Harris J, Devidze N, Dubal DB, et al. 2011. Reversing EphB2 depletion rescues cognitive functions in Alzheimer model. Nature 469:47-52
-
(2011)
Nature
, vol.469
, pp. 47-52
-
-
Cisse, M.1
Halabisky, B.2
Harris, J.3
Devidze, N.4
Dubal, D.B.5
-
52
-
-
84899124597
-
EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-beta oligomers
-
Vargas LM, Leal N, Estrada LD, Gonzalez A, Serrano F, et al. 2014. EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-beta oligomers. PLOS ONE 9:e92309
-
(2014)
Plos One
, vol.9
, pp. e92309
-
-
Vargas, L.M.1
Leal, N.2
Estrada, L.D.3
Gonzalez, A.4
Serrano, F.5
-
53
-
-
84903978323
-
Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimers disease
-
Fu AK, Hung KW, Huang H, Gu S, Shen Y, et al. 2014. Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimers disease. Proc. Natl. Acad. Sci. USA 111:9959-64
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 9959-9964
-
-
Fu, A.K.1
Hung, K.W.2
Huang, H.3
Gu, S.4
Shen, Y.5
-
54
-
-
84896549076
-
Ligand-dependent activation of EphA4 signaling regulates the proteolysis of amyloid precursor protein through a Lyn-mediated pathway
-
Lai WB, Wang BJ, Hu MK, Hsu WM, Her GM, Liao YF. 2014. Ligand-dependent activation of EphA4 signaling regulates the proteolysis of amyloid precursor protein through a Lyn-mediated pathway. Mol. Neurobiol. 49:1055-68
-
(2014)
Mol. Neurobiol.
, vol.49
, pp. 1055-1068
-
-
Lai, W.B.1
Wang, B.J.2
Hu, M.K.3
Hsu, W.M.4
Her, G.M.5
Liao, Y.F.6
-
55
-
-
84867573082
-
Involvement of the γ-secretasemediated EphA4 signaling pathway in synaptic pathogenesis of Alzheimers disease
-
Matsui C, Inoue E, Kakita A, Arita K, Deguchi-Tawarada M, et al. 2012. Involvement of the γ-secretasemediated EphA4 signaling pathway in synaptic pathogenesis of Alzheimers disease. Brain Pathol. 22:776-87
-
(2012)
Brain Pathol.
, vol.22
, pp. 776-787
-
-
Matsui, C.1
Inoue, E.2
Kakita, A.3
Arita, K.4
Deguchi-Tawarada, M.5
-
56
-
-
84869079655
-
Presenilin mediates neuroprotective functions of ephrinB and brain-derived neurotrophic factor and regulates ligand-induced internalization and metabolism of EphB2 and TrkB receptors
-
Barthet G, Dunys J, Shao Z, Xuan Z, Ren Y, et al. 2013. Presenilin mediates neuroprotective functions of ephrinB and brain-derived neurotrophic factor and regulates ligand-induced internalization and metabolism of EphB2 and TrkB receptors. Neurobiol. Aging 34:499-510
-
(2013)
Neurobiol. Aging
, vol.34
, pp. 499-510
-
-
Barthet, G.1
Dunys, J.2
Shao, Z.3
Xuan, Z.4
Ren, Y.5
-
57
-
-
84865468329
-
The genetics and neuropathology of Alzheimers disease
-
Schellenberg GD, Montine TJ. 2012. The genetics and neuropathology of Alzheimers disease. Acta Neuropathol. 124:305-23
-
(2012)
Acta Neuropathol.
, vol.124
, pp. 305-323
-
-
Schellenberg, G.D.1
Montine, T.J.2
-
58
-
-
61649111726
-
Axon guidance and synaptic maintenance: Preclinical markers for neurodegenerative disease and therapeutics
-
Lin L, Lesnick TG, Maraganore DM, Isacson O. 2009. Axon guidance and synaptic maintenance: preclinical markers for neurodegenerative disease and therapeutics. Trends Neurosci. 32:142-49
-
(2009)
Trends Neurosci.
, vol.32
, pp. 142-149
-
-
Lin, L.1
Lesnick, T.G.2
Maraganore, D.M.3
Isacson, O.4
-
59
-
-
84857396773
-
Ephrin-A1-mediated dopaminergic neurogenesis and angiogenesis in a rat model of Parkinsons disease
-
Jing X, Miwa H, Sawada T, Nakanishi I, Kondo T, et al. 2012. Ephrin-A1-mediated dopaminergic neurogenesis and angiogenesis in a rat model of Parkinsons disease. PLOS ONE 7:e32019
-
(2012)
Plos One
, vol.7
, pp. e32019
-
-
Jing, X.1
Miwa, H.2
Sawada, T.3
Nakanishi, I.4
Kondo, T.5
-
60
-
-
84872451712
-
Involvement of EphB1 receptors signalling in models of inflammatory and neuropathic pain
-
Cibert-Goton V, Yuan G, Battaglia A, Fredriksson S, Henkemeyer M, et al. 2013. Involvement of EphB1 receptors signalling in models of inflammatory and neuropathic pain. PLOS ONE 8:e53673
-
(2013)
Plos One
, vol.8
, pp. e53673
-
-
Cibert-Goton, V.1
Yuan, G.2
Battaglia, A.3
Fredriksson, S.4
Henkemeyer, M.5
-
61
-
-
84883172515
-
Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy
-
Leandro-Garcia LJ, Inglada-Perez L, Pita G, Hjerpe E, Leskela S, et al. 2013. Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy. J. Med. Genet. 50:599-605
-
(2013)
J. Med. Genet.
, vol.50
, pp. 599-605
-
-
Leandro-Garcia, L.J.1
Inglada-Perez, L.2
Pita, G.3
Hjerpe, E.4
Leskela, S.5
-
62
-
-
33750610175
-
Blocking EphA4 upregulation after spinal cord injury results in enhanced chronic pain
-
Cruz-Orengo L, Figueroa JD, Velazquez I, Torrado A, Ortz C, et al. 2006. Blocking EphA4 upregulation after spinal cord injury results in enhanced chronic pain. Exp. Neurol. 202:421-33
-
(2006)
Exp. Neurol.
, vol.202
, pp. 421-433
-
-
Cruz-Orengo, L.1
Figueroa, J.D.2
Velazquez, I.3
Torrado, A.4
Ortz, C.5
-
64
-
-
33846217879
-
A critical role for the EphA3 receptor tyrosine kinase in heart development
-
Stephen LJ, Fawkes AL, Verhoeve A, Lemke G, Brown A. 2007. A critical role for the EphA3 receptor tyrosine kinase in heart development. Dev. Biol. 302:66-79
-
(2007)
Dev. Biol.
, vol.302
, pp. 66-79
-
-
Stephen, L.J.1
Fawkes, A.L.2
Verhoeve, A.3
Lemke, G.4
Brown, A.5
-
65
-
-
78649688488
-
Regulation of heart valve morphogenesis by Eph receptor ligand, ephrin-A1
-
Frieden LA, Townsend TA, Vaught DB, Delaughter DM, Hwang Y, et al. 2010. Regulation of heart valve morphogenesis by Eph receptor ligand, ephrin-A1. Dev. Dyn. 239:3226-34
-
(2010)
Dev. Dyn.
, vol.239
, pp. 3226-3234
-
-
Frieden, L.A.1
Townsend, T.A.2
Vaught, D.B.3
Delaughter, D.M.4
Hwang, Y.5
-
66
-
-
84860807231
-
Essential roles of EphB receptors and EphrinB ligands in endothelial cell function and angiogenesis
-
Salvucci O, Tosato G. 2012. Essential roles of EphB receptors and EphrinB ligands in endothelial cell function and angiogenesis. Adv. Cancer Res. 114:21-57
-
(2012)
Adv. Cancer Res.
, vol.114
, pp. 21-57
-
-
Salvucci, O.1
Tosato, G.2
-
67
-
-
84879391391
-
Ephrin-A1/EphA4-mediated adhesion of monocytes to endothelial cells
-
Jellinghaus S, Poitz DM, Ende G, Augstein A, Weinert S, et al. 2013. Ephrin-A1/EphA4-mediated adhesion of monocytes to endothelial cells. Biochim. Biophys. Acta 1833:2201-11
-
(2013)
Biochim. Biophys. Acta
, vol.1833
, pp. 2201-2211
-
-
Jellinghaus, S.1
Poitz, D.M.2
Ende, G.3
Augstein, A.4
Weinert, S.5
-
68
-
-
84857439435
-
EphA receptor signaling-complexity and emerging themes
-
Miao H, Wang B. 2012. EphA receptor signaling-complexity and emerging themes. Semin. Cell Dev. Biol. 23:16-25
-
(2012)
Semin. Cell Dev. Biol.
, vol.23
, pp. 16-25
-
-
Miao, H.1
Wang, B.2
-
69
-
-
84860848502
-
Possible role of Efnb1 protein, a ligand of Eph receptor tyrosine kinases, in modulating blood pressure
-
Wu Z, Luo H, Thorin E, Tremblay J, Peng J, et al. 2012. Possible role of Efnb1 protein, a ligand of Eph receptor tyrosine kinases, in modulating blood pressure. J. Biol. Chem. 287:15557-69
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 15557-15569
-
-
Wu, Z.1
Luo, H.2
Thorin, E.3
Tremblay, J.4
Peng, J.5
-
70
-
-
4344679183
-
Eph receptor tyrosine kinases in angiogenesis: From development to disease
-
Brantley-Sieders DM, Chen J. 2004. Eph receptor tyrosine kinases in angiogenesis: from development to disease. Angiogenesis 7:17-28
-
(2004)
Angiogenesis
, vol.7
, pp. 17-28
-
-
Brantley-Sieders, D.M.1
Chen, J.2
-
71
-
-
81155126187
-
EphA2-dependent molecular targeting therapy for malignant tumors
-
Biao-Xue R, Xi-Guang C, Shuan-Ying Y, Wei L, Zong-Juan M. 2011. EphA2-dependent molecular targeting therapy for malignant tumors. Curr. Cancer Drug Targets 11:1082-97
-
(2011)
Curr. Cancer Drug Targets
, vol.11
, pp. 1082-1097
-
-
Biao-Xue, R.1
Xi-Guang, C.2
Shuan-Ying, Y.3
Wei, L.4
Zong-Juan, M.5
-
72
-
-
84874622432
-
Spatial regulation of VEGF receptor endocytosis in angiogenesis
-
Nakayama M, Nakayama A, van Lessen M, Yamamoto H, Hoffmann S, et al. 2013. Spatial regulation of VEGF receptor endocytosis in angiogenesis. Nat. Cell Biol. 15:249-60
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 249-260
-
-
Nakayama, M.1
Nakayama, A.2
Van Lessen, M.3
Yamamoto, H.4
Hoffmann, S.5
-
73
-
-
77950577414
-
Novel EphB4 monoclonal antibodies modulate angiogenesis and inhibit tumor growth
-
Krasnoperov V, Kumar SR, Ley E, Li X, Scehnet J, et al. 2010. Novel EphB4 monoclonal antibodies modulate angiogenesis and inhibit tumor growth. Am. J. Pathol. 176:2029-38
-
(2010)
Am. J. Pathol.
, vol.176
, pp. 2029-2038
-
-
Krasnoperov, V.1
Kumar, S.R.2
Ley, E.3
Li, X.4
Scehnet, J.5
-
74
-
-
80052803473
-
DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo
-
Li JL, Sainson RC, Oon CE, Turley H, Leek R, et al. 2011. DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo. Cancer Res. 71:6073-83
-
(2011)
Cancer Res.
, vol.71
, pp. 6073-6083
-
-
Li, J.L.1
Sainson, R.C.2
Oon, C.E.3
Turley, H.4
Leek, R.5
-
75
-
-
79955593546
-
The ephrin A1-EphA2 system promotes cardiac stem cell migration after infarction
-
Goichberg P, Bai Y, DAmario D, Ferreira-Martins J, Fiorini C, et al. 2011. The ephrin A1-EphA2 system promotes cardiac stem cell migration after infarction. Circ. Res. 108:1071-83
-
(2011)
Circ. Res.
, vol.108
, pp. 1071-1083
-
-
Goichberg, P.1
Bai, Y.2
Damario, D.3
Ferreira-Martins, J.4
Fiorini, C.5
-
76
-
-
84887625615
-
Age-associated defects in EphA2 signaling impair the migration of human cardiac progenitor cells
-
Goichberg P, Kannappan R, Cimini M, Bai Y, Sanada F, et al. 2013. Age-associated defects in EphA2 signaling impair the migration of human cardiac progenitor cells. Circulation 128:2211-23
-
(2013)
Circulation
, vol.128
, pp. 2211-2223
-
-
Goichberg, P.1
Kannappan, R.2
Cimini, M.3
Bai, Y.4
Sanada, F.5
-
77
-
-
79953154439
-
Intramyocardial administration of chimeric ephrinA1-Fc promotes tissue salvage following myocardial infarction in mice
-
Dries JL, Kent SD, Virag JA. 2011. Intramyocardial administration of chimeric ephrinA1-Fc promotes tissue salvage following myocardial infarction in mice. J. Physiol. 589:1725-40
-
(2011)
J. Physiol.
, vol.589
, pp. 1725-1740
-
-
Dries, J.L.1
Kent, S.D.2
Virag, J.A.3
-
78
-
-
47249109311
-
Modulation of ephrinB2 leads to increased angiogenesis in ischemic myocardium and endothelial cell proliferation
-
Mansson-Broberg A, Siddiqui AJ, Genander M, Grinnemo KH, Hao X, et al. 2008. Modulation of ephrinB2 leads to increased angiogenesis in ischemic myocardium and endothelial cell proliferation. Biochem. Biophys. Res. Commun. 373:355-59
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.373
, pp. 355-359
-
-
Mansson-Broberg, A.1
Siddiqui, A.J.2
Genander, M.3
Grinnemo, K.H.4
Hao, X.5
-
79
-
-
84856703233
-
EphB signaling inhibits gap junctional intercellular communication and synchronized contraction in cultured cardiomyocytes
-
Ishii M, Mueller I, Nakajima T, Pasquale EB, Ogawa K. 2011. EphB signaling inhibits gap junctional intercellular communication and synchronized contraction in cultured cardiomyocytes. Basic Res. Cardiol. 106:1057-68
-
(2011)
Basic Res. Cardiol.
, vol.106
, pp. 1057-1068
-
-
Ishii, M.1
Mueller, I.2
Nakajima, T.3
Pasquale, E.B.4
Ogawa, K.5
-
80
-
-
84887467125
-
Therapeutic synergy between microRNA and siRNA in ovarian cancer treatment
-
Nishimura M, Jung EJ, Shah MY, Lu C, Spizzo R, et al. 2013. Therapeutic synergy between microRNA and siRNA in ovarian cancer treatment. Cancer Discov. 3:1302-15
-
(2013)
Cancer Discov.
, vol.3
, pp. 1302-1315
-
-
Nishimura, M.1
Jung, E.J.2
Shah, M.Y.3
Lu, C.4
Spizzo, R.5
-
81
-
-
84857384965
-
Cancer somatic mutations disrupt functions of the EphA3 receptor tyrosine kinase through multiple mechanisms
-
Lisabeth EM, Fernandez C, Pasquale EB. 2012. Cancer somatic mutations disrupt functions of the EphA3 receptor tyrosine kinase through multiple mechanisms. Biochemistry 51:1464-75
-
(2012)
Biochemistry
, vol.51
, pp. 1464-1475
-
-
Lisabeth, E.M.1
Fernandez, C.2
Pasquale, E.B.3
-
82
-
-
84864951407
-
Effects of cancer-associated EPHA3 mutations on lung cancer
-
Zhuang G, Song W, Amato K, Hwang Y, Lee K, et al. 2012. Effects of cancer-associated EPHA3 mutations on lung cancer. J. Natl. Cancer Inst. 104:1182-97
-
(2012)
J. Natl. Cancer Inst.
, vol.104
, pp. 1182-1197
-
-
Zhuang, G.1
Song, W.2
Amato, K.3
Hwang, Y.4
Lee, K.5
-
83
-
-
83555166269
-
EphA2 is a critical oncogene in melanoma
-
Udayakumar D, Zhang G, Ji Z, Njauw CN, Mroz P, Tsao H. 2011. EphA2 is a critical oncogene in melanoma. Oncogene 30:4921-29
-
(2011)
Oncogene
, vol.30
, pp. 4921-4929
-
-
Udayakumar, D.1
Zhang, G.2
Ji, Z.3
Njauw, C.N.4
Mroz, P.5
Tsao, H.6
-
84
-
-
0038068866
-
EphA2 overexpression decreases estrogen dependence and tamoxifen sensitivity
-
Lu M, Miller KD, Gokmen-Polar Y, Jeng M-H, Kinch MS. 2003. EphA2 overexpression decreases estrogen dependence and tamoxifen sensitivity. Cancer Res. 63:3425-29
-
(2003)
Cancer Res.
, vol.63
, pp. 3425-3429
-
-
Lu, M.1
Miller, K.D.2
Gokmen-Polar, Y.3
Jeng, M.-H.4
Kinch, M.S.5
-
85
-
-
79958240217
-
Dual targeting of EphA2 and ER restores tamoxifen sensitivity in ER/EphA2-positive breast cancer
-
Gokmen-Polar Y, Toroni RA, Hocevar BA, Badve S, Zhao Q, et al. 2011. Dual targeting of EphA2 and ER restores tamoxifen sensitivity in ER/EphA2-positive breast cancer. Breast Cancer Res. Treat. 127:375-84
-
(2011)
Breast Cancer Res. Treat.
, vol.127
, pp. 375-384
-
-
Gokmen-Polar, Y.1
Toroni, R.A.2
Hocevar, B.A.3
Badve, S.4
Zhao, Q.5
-
86
-
-
75149129568
-
Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy
-
Zhuang G, Brantley-Sieders DM, Vaught D, Yu J, Xie L, et al. 2010. Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy. Cancer Res. 70:299-308
-
(2010)
Cancer Res.
, vol.70
, pp. 299-308
-
-
Zhuang, G.1
Brantley-Sieders, D.M.2
Vaught, D.3
Yu, J.4
Xie, L.5
-
87
-
-
84872176286
-
Inhibition of Ephrin B3-mediated survival signaling contributes to increased cell death response of non-small cell lung carcinoma cells after combined treatment with ionizing radiation and PKC 412
-
Stahl S, Kaminskyy VO, Efazat G, Hyrslova Vaculova A, Rodriguez-Nieto S, et al. 2013. Inhibition of Ephrin B3-mediated survival signaling contributes to increased cell death response of non-small cell lung carcinoma cells after combined treatment with ionizing radiation and PKC 412. Cell Death Dis. 4:e454
-
(2013)
Cell Death Dis.
, vol.4
, pp. e454
-
-
Stahl, S.1
Kaminskyy, V.O.2
Efazat, G.3
Hyrslova Vaculova, A.4
Rodriguez-Nieto, S.5
-
88
-
-
80755142709
-
Role of Eph/ephrin tyrosine kinase in malignant glioma
-
Nakada M, Hayashi Y, Hamada J. 2011. Role of Eph/ephrin tyrosine kinase in malignant glioma. Neuro Oncol. 13:1163-70
-
(2011)
Neuro Oncol.
, vol.13
, pp. 1163-1170
-
-
Nakada, M.1
Hayashi, Y.2
Hamada, J.3
-
89
-
-
84873592755
-
EphA3 maintains tumorigenicity and is a therapeutic target in glioblastoma multiforme
-
Day BW, Stringer BW, Al-Ejeh F, Ting MJ, Wilson J, et al. 2013. EphA3 maintains tumorigenicity and is a therapeutic target in glioblastoma multiforme. Cancer Cell 23:238-48
-
(2013)
Cancer Cell
, vol.23
, pp. 238-248
-
-
Day, B.W.1
Stringer, B.W.2
Al-Ejeh, F.3
Ting, M.J.4
Wilson, J.5
-
90
-
-
85028252412
-
EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties
-
In press. doi: 10.1038/onc.2013.590
-
Miao H, Gale NW, Guo H, Qian J, Petty A, et al. 2014. EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties. Oncogene. In press. doi: 10. 1038/onc. 2013. 590
-
(2014)
Oncogene
-
-
Miao, H.1
Gale, N.W.2
Guo, H.3
Qian, J.4
Petty, A.5
-
91
-
-
77957783252
-
Crosstalk of the EphA2 receptor with a serine/threonine phosphatase suppresses the Akt-mTORC1 pathway in cancer cells
-
Yang NY, Fernandez C, Richter M, Xiao Z, Valencia F, et al. 2011. Crosstalk of the EphA2 receptor with a serine/threonine phosphatase suppresses the Akt-mTORC1 pathway in cancer cells. Cell Signal. 23:201-12
-
(2011)
Cell Signal.
, vol.23
, pp. 201-212
-
-
Yang, N.Y.1
Fernandez, C.2
Richter, M.3
Xiao, Z.4
Valencia, F.5
-
92
-
-
84871191999
-
EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase
-
Wang SD, Rath P, Lal B, Richard JP, Li Y, et al. 2012. EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase. Oncogene 31:5132-43
-
(2012)
Oncogene
, vol.31
, pp. 5132-5143
-
-
Wang, S.D.1
Rath, P.2
Lal, B.3
Richard, J.P.4
Li, Y.5
-
93
-
-
84872580192
-
Loss of miR-204 expression enhances glioma migration and stem cell-like phenotype
-
Ying Z, Li Y, Wu J, Zhu X, Yang Y, et al. 2013. Loss of miR-204 expression enhances glioma migration and stem cell-like phenotype. Cancer Res. 73:990-99
-
(2013)
Cancer Res.
, vol.73
, pp. 990-999
-
-
Ying, Z.1
Li, Y.2
Wu, J.3
Zhu, X.4
Yang, Y.5
-
94
-
-
77955175049
-
Cross-species genomics matches driver mutations and cell compartments to model ependymoma
-
Johnson RA, Wright KD, Poppleton H, Mohankumar KM, Finkelstein D, et al. 2010. Cross-species genomics matches driver mutations and cell compartments to model ependymoma. Nature 466:632-36
-
(2010)
Nature
, vol.466
, pp. 632-636
-
-
Johnson, R.A.1
Wright, K.D.2
Poppleton, H.3
Mohankumar, K.M.4
Finkelstein, D.5
-
95
-
-
84870737113
-
The roles and therapeutic potentials of Ephs and ephrins in lung cancer
-
Li JJ, Xie D. 2013. The roles and therapeutic potentials of Ephs and ephrins in lung cancer. Exp. Cell Res. 319:152-59
-
(2013)
Exp. Cell Res.
, vol.319
, pp. 152-159
-
-
Li, J.J.1
Xie, D.2
-
96
-
-
84866118854
-
Global evaluation of Eph receptors and ephrins in lung adenocarcinomas identifies EphA4 as an inhibitor of cell migration and invasion
-
Saintigny P, Peng S, Zhang L, Sen B, Wistuba II, et al. 2012. Global evaluation of Eph receptors and ephrins in lung adenocarcinomas identifies EphA4 as an inhibitor of cell migration and invasion. Mol. Cancer Ther. 11:2021-32
-
(2012)
Mol. Cancer Ther.
, vol.11
, pp. 2021-2032
-
-
Saintigny, P.1
Peng, S.2
Zhang, L.3
Sen, B.4
Wistuba, I.I.5
-
97
-
-
84900007107
-
JNK signaling mediates EPHA2-dependent tumor cell proliferation, motility, and cancer stem cell-like properties in non-small cell lung cancer
-
Song W, Ma Y, Wang J, Brantley-Sieders D, Chen J. 2014. JNK signaling mediates EPHA2-dependent tumor cell proliferation, motility, and cancer stem cell-like properties in non-small cell lung cancer. Cancer Res. 74:2444-54
-
(2014)
Cancer Res.
, vol.74
, pp. 2444-2454
-
-
Song, W.1
Ma, Y.2
Wang, J.3
Brantley-Sieders, D.4
Chen, J.5
-
98
-
-
84899739937
-
Genetic and pharmacologic inhibition of EPHA2 promotes apoptosis in NSCLC
-
Amato KR, Wang S, Hastings AK, Youngblood VM, Santapuram PR, et al. 2014. Genetic and pharmacologic inhibition of EPHA2 promotes apoptosis in NSCLC. J. Clin. Investig. 124:2037-49
-
(2014)
J. Clin. Investig.
, vol.124
, pp. 2037-2049
-
-
Amato, K.R.1
Wang, S.2
Hastings, A.K.3
Youngblood, V.M.4
Santapuram, P.R.5
-
99
-
-
54549094903
-
Somatic mutations affect key pathways in lung adenocarcinoma
-
Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, et al. 2008. Somatic mutations affect key pathways in lung adenocarcinoma. Nature 455:1069-75
-
(2008)
Nature
, vol.455
, pp. 1069-1075
-
-
Ding, L.1
Getz, G.2
Wheeler, D.A.3
Mardis, E.R.4
McLellan, M.D.5
-
100
-
-
79551542878
-
EphB3 is overexpressed in non-small-cell lung cancer and promotes tumor metastasis by enhancing cell survival and migration
-
Ji XD, Li G, Feng YX, Zhao JS, Li JJ, et al. 2011. EphB3 is overexpressed in non-small-cell lung cancer and promotes tumor metastasis by enhancing cell survival and migration. Cancer Res. 71:1156-66
-
(2011)
Cancer Res.
, vol.71
, pp. 1156-1166
-
-
Ji, X.D.1
Li, G.2
Feng, Y.X.3
Zhao, J.S.4
Li, J.J.5
-
101
-
-
84863262889
-
EphB3 suppresses non-small-cell lung cancermetastasis via a PP2A/RACK1/Akt signalling complex
-
Li G, Ji XD, Gao H, Zhao JS, Xu JF, et al. 2012. EphB3 suppresses non-small-cell lung cancermetastasis via a PP2A/RACK1/Akt signalling complex. Nat. Commun. 3:667
-
(2012)
Nat. Commun.
, vol.3
, pp. 667
-
-
Li, G.1
Ji, X.D.2
Gao, H.3
Zhao, J.S.4
Xu, J.F.5
-
102
-
-
84879766932
-
The EphB4 receptor tyrosine kinase promotes lung cancer growth: A potential novel therapeutic target
-
Ferguson BD, Liu R, Rolle CE, Tan YH, Krasnoperov V, et al. 2013. The EphB4 receptor tyrosine kinase promotes lung cancer growth: A potential novel therapeutic target. PLOS ONE 8:e67668
-
(2013)
Plos One
, vol.8
, pp. e67668
-
-
Ferguson, B.D.1
Liu, R.2
Rolle, C.E.3
Tan, Y.H.4
Krasnoperov, V.5
-
103
-
-
84870755448
-
Mutations of the EPHB6 receptor tyrosine kinase induce a pro-metastatic phenotype in non-small cell lung cancer
-
Bulk E, Yu J, Hascher A, Koschmieder S, Wiewrodt R, et al. 2012. Mutations of the EPHB6 receptor tyrosine kinase induce a pro-metastatic phenotype in non-small cell lung cancer. PLOS ONE 7:e44591
-
(2012)
Plos One
, vol.7
, pp. e44591
-
-
Bulk, E.1
Yu, J.2
Hascher, A.3
Koschmieder, S.4
Wiewrodt, R.5
-
104
-
-
84862528348
-
Moving beyond VEGF for anti-angiogenesis strategies in gynecologic cancer
-
Thanapprapasr D, Hu W, Sood AK, Coleman RL. 2012. Moving beyond VEGF for anti-angiogenesis strategies in gynecologic cancer. Curr. Pharm. Des. 18:2713-19
-
(2012)
Curr. Pharm. Des.
, vol.18
, pp. 2713-2719
-
-
Thanapprapasr, D.1
Hu, W.2
Sood, A.K.3
Coleman, R.L.4
-
105
-
-
78649651321
-
EphB4 promotes site-specificmetastatic tumor cell dissemination by interacting with endothelial cell-expressed ephrinB2
-
Heroult M, Schaffner F, Pfaff D, Prahst C, Kirmse R, et al. 2010. EphB4 promotes site-specificmetastatic tumor cell dissemination by interacting with endothelial cell-expressed ephrinB2. Mol. Cancer Res. 8:1297-309
-
(2010)
Mol. Cancer Res.
, vol.8
, pp. 1297-1309
-
-
Heroult, M.1
Schaffner, F.2
Pfaff, D.3
Prahst, C.4
Kirmse, R.5
-
106
-
-
84857443530
-
Ephrin-B2 and ephrin-B3 as functional henipavirus receptors
-
Xu K, Broder CC, Nikolov DB. 2012. Ephrin-B2 and ephrin-B3 as functional henipavirus receptors. Semin. Cell Dev. Biol. 23:116-23
-
(2012)
Semin. Cell Dev. Biol.
, vol.23
, pp. 116-123
-
-
Xu, K.1
Broder, C.C.2
Nikolov, D.B.3
-
107
-
-
80055067852
-
The mouse IAPE endogenous retrovirus can infect cells through any of the five GPI-anchored Ephrin A proteins
-
Dewannieux M, Vernochet C, Ribet D, Bartosch B, Cosset FL, Heidmann T. 2011. The mouse IAPE endogenous retrovirus can infect cells through any of the five GPI-anchored Ephrin A proteins. PLOS Pathog. 7:e1002309
-
(2011)
PLOS Pathog.
, vol.7
, pp. e1002309
-
-
Dewannieux, M.1
Vernochet, C.2
Ribet, D.3
Bartosch, B.4
Cosset, F.L.5
Heidmann, T.6
-
108
-
-
84860832684
-
Kaposis sarcoma-associated herpesvirus interacts with EphrinA2 receptor to amplify signaling essential for productive infection
-
Chakraborty S, Veettil MV, Bottero V, Chandran B. 2012. Kaposis sarcoma-associated herpesvirus interacts with EphrinA2 receptor to amplify signaling essential for productive infection. Proc. Natl. Acad. Sci. USA 109:E1163-72
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. E1163-E1172
-
-
Chakraborty, S.1
Veettil, M.V.2
Bottero, V.3
Chandran, B.4
-
109
-
-
84862016090
-
The ephrin receptor tyrosine kinase A2 is a cellular receptor forKaposis sarcoma-associated herpesvirus
-
Hahn AS, Kaufmann JK, Wies E, Naschberger E, Panteleev-Ivlev J, et al. 2012. The ephrin receptor tyrosine kinase A2 is a cellular receptor forKaposis sarcoma-associated herpesvirus. Nat. Med. 18:961-66
-
(2012)
Nat. Med.
, vol.18
, pp. 961-966
-
-
Hahn, A.S.1
Kaufmann, J.K.2
Wies, E.3
Naschberger, E.4
Panteleev-Ivlev, J.5
-
110
-
-
79955692689
-
EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy
-
Lupberger J, Zeisel MB, Xiao F, Thumann C, Fofana I, et al. 2011. EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy. Nat. Med. 17:589-95
-
(2011)
Nat. Med.
, vol.17
, pp. 589-595
-
-
Lupberger, J.1
Zeisel, M.B.2
Xiao, F.3
Thumann, C.4
Fofana, I.5
-
111
-
-
84870792928
-
Hsp90 inhibitors are efficacious against Kaposi sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins
-
Chen W, Sin SH, Wen KW, Damania B, Dittmer DP. 2012. Hsp90 inhibitors are efficacious against Kaposi sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins. PLOS Pathog. 8:e1003048
-
(2012)
PLOS Pathog.
, vol.8
, pp. e1003048
-
-
Chen, W.1
Sin, S.H.2
Wen, K.W.3
Damania, B.4
Dittmer, D.P.5
-
112
-
-
76749090540
-
Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication
-
Karlas A, Machuy N, Shin Y, Pleissner KP, Artarini A, et al. 2010. Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication. Nature 463:818-22
-
(2010)
Nature
, vol.463
, pp. 818-822
-
-
Karlas, A.1
Machuy, N.2
Shin, Y.3
Pleissner, K.P.4
Artarini, A.5
-
113
-
-
77957244402
-
Ephrins and Eph receptors in stem cells and cancer
-
Genander M, Frisen J. 2010. Ephrins and Eph receptors in stem cells and cancer. Curr. Opin. Cell Biol. 22:611-16
-
(2010)
Curr. Opin. Cell Biol.
, vol.22
, pp. 611-616
-
-
Genander, M.1
Frisen, J.2
-
114
-
-
84863893647
-
Bone cell interactions through Eph/ephrin: Bone modeling, remodeling and associated diseases
-
Matsuo K, Otaki N. 2012. Bone cell interactions through Eph/ephrin: bone modeling, remodeling and associated diseases. Cell Adhes. Migr. 6:148-56
-
(2012)
Cell Adhes. Migr.
, vol.6
, pp. 148-156
-
-
Matsuo, K.1
Otaki, N.2
-
115
-
-
84857444836
-
Eph/ephrin signaling in epidermal differentiation and disease
-
Lin S, Wang B, Getsios S. 2012. Eph/ephrin signaling in epidermal differentiation and disease. Semin. Cell Dev. Biol. 23:92-101
-
(2012)
Semin. Cell Dev. Biol.
, vol.23
, pp. 92-101
-
-
Lin, S.1
Wang, B.2
Getsios, S.3
-
116
-
-
84873737067
-
Alteration of the EphA2/ephrin-A signaling axis in psoriatic epidermis
-
Gordon K, Kochkodan JJ, Blatt H, Lin SY, Kaplan N, et al. 2013. Alteration of the EphA2/ephrin-A signaling axis in psoriatic epidermis. J. Investig. Dermatol. 133:712-22
-
(2013)
J. Investig. Dermatol.
, vol.133
, pp. 712-722
-
-
Gordon, K.1
Kochkodan, J.J.2
Blatt, H.3
Lin, S.Y.4
Kaplan, N.5
-
117
-
-
77954823673
-
Ephrins negatively regulate cell proliferation in the epidermis and hair follicle
-
Genander M, Holmberg J, Frisen J. 2010. Ephrins negatively regulate cell proliferation in the epidermis and hair follicle. Stem Cells 28:1196-205
-
(2010)
Stem Cells
, vol.28
, pp. 1196-1205
-
-
Genander, M.1
Holmberg, J.2
Frisen, J.3
-
118
-
-
84875480255
-
EphA5-EphrinA5 interactions within the ventromedial hypothalamus influence counterregulatory hormone release and local glutamine/glutamate balance during hypoglycemia
-
Szepietowska B, Zhu W, Czyzyk J, Eid T, Sherwin RS. 2013. EphA5-EphrinA5 interactions within the ventromedial hypothalamus influence counterregulatory hormone release and local glutamine/glutamate balance during hypoglycemia. Diabetes 62:1282-88
-
(2013)
Diabetes
, vol.62
, pp. 1282-1288
-
-
Szepietowska, B.1
Zhu, W.2
Czyzyk, J.3
Eid, T.4
Sherwin, R.S.5
-
119
-
-
84877781324
-
Pharmacological inhibition of Eph receptors enhances glucose-stimulated insulin secretion from mouse and human pancreatic islets
-
Jain R, Jain D, Liu Q, Bartosinska B, Wang J, et al. 2013. Pharmacological inhibition of Eph receptors enhances glucose-stimulated insulin secretion from mouse and human pancreatic islets. Diabetologia 56:1350-55
-
(2013)
Diabetologia
, vol.56
, pp. 1350-1355
-
-
Jain, R.1
Jain, D.2
Liu, Q.3
Bartosinska, B.4
Wang, J.5
-
120
-
-
77958163776
-
Is the EFNB2 locus associated with schizophrenia? Single nucleotide polymorphisms and haplotypes analysis
-
Zhang R, Zhong NN, Liu XG, Yan H, Qiu C, et al. 2010. Is the EFNB2 locus associated with schizophrenia? Single nucleotide polymorphisms and haplotypes analysis. Psychiatry Res. 180:5-9
-
(2010)
Psychiatry Res.
, vol.180
, pp. 5-9
-
-
Zhang, R.1
Zhong, N.N.2
Liu, X.G.3
Yan, H.4
Qiu, C.5
-
121
-
-
84862829848
-
Biophysical characterization and stabilization of the recombinant albumin fusion protein sEphB4-HSA
-
Shi S, Liu J, Joshi SB, Krasnoperov V, Gill P, et al. 2012. Biophysical characterization and stabilization of the recombinant albumin fusion protein sEphB4-HSA. J. Pharm. Sci. 101:1969-84
-
(2012)
J. Pharm. Sci.
, vol.101
, pp. 1969-1984
-
-
Shi, S.1
Liu, J.2
Joshi, S.B.3
Krasnoperov, V.4
Gill, P.5
-
122
-
-
78549253191
-
Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis
-
Djokovic D, Trindade A, Gigante J, Badenes M, Silva L, et al. 2010. Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis. BMC Cancer 10:641
-
(2010)
BMC Cancer
, vol.10
, pp. 641
-
-
Djokovic, D.1
Trindade, A.2
Gigante, J.3
Badenes, M.4
Silva, L.5
-
123
-
-
78649869202
-
Ocular safety profile and intraocular pharmacokinetics of an antagonist of EphB4/EphrinB2 signalling
-
Brar M, Cheng L, Yuson R, Mojana F, Freeman WR, Gill PS. 2010. Ocular safety profile and intraocular pharmacokinetics of an antagonist of EphB4/EphrinB2 signalling. Br. J. Ophthalmol. 94:1668-73
-
(2010)
Br. J. Ophthalmol.
, vol.94
, pp. 1668-1673
-
-
Brar, M.1
Cheng, L.2
Yuson, R.3
Mojana, F.4
Freeman, W.R.5
Gill, P.S.6
-
124
-
-
59449103839
-
The role of Ephs, Ephrins, and growth factors in Kaposi sarcoma and implications of EphrinB2 blockade
-
Scehnet JS, Ley EJ, Krasnoperov V, Liu R, Manchanda PK, et al. 2009. The role of Ephs, Ephrins, and growth factors in Kaposi sarcoma and implications of EphrinB2 blockade. Blood 113:254-63
-
(2009)
Blood
, vol.113
, pp. 254-263
-
-
Scehnet, J.S.1
Ley, E.J.2
Krasnoperov, V.3
Liu, R.4
Manchanda, P.K.5
-
125
-
-
80155148301
-
The eph-receptor a7 is a soluble tumor suppressor for follicular lymphoma
-
Oricchio E, Nanjangud G, Wolfe AL, Schatz JH, Mavrakis KJ, et al. 2011. The eph-receptor a7 is a soluble tumor suppressor for follicular lymphoma. Cell 147:554-64
-
(2011)
Cell
, vol.147
, pp. 554-564
-
-
Oricchio, E.1
Nanjangud, G.2
Wolfe, A.L.3
Schatz, J.H.4
Mavrakis, K.J.5
-
126
-
-
1242317764
-
Engineered fibrin matrices for functional display of cell membrane-bound growth factor-like activities: Study of angiogenic signaling by ephrin-B2
-
Zisch AH, Zeisberger SM, Ehrbar M, Djonov V, Weber CC, et al. 2004. Engineered fibrin matrices for functional display of cell membrane-bound growth factor-like activities: study of angiogenic signaling by ephrin-B2. Biomaterials 25:3245-57
-
(2004)
Biomaterials
, vol.25
, pp. 3245-3257
-
-
Zisch, A.H.1
Zeisberger, S.M.2
Ehrbar, M.3
Djonov, V.4
Weber, C.C.5
-
127
-
-
79960212030
-
Biomimetic hydrogels with immobilized ephrinA1 for therapeutic angiogenesis
-
Saik JE, Gould DJ, Keswani AH, Dickinson ME, West JL. 2011. Biomimetic hydrogels with immobilized ephrinA1 for therapeutic angiogenesis. Biomacromolecules 12:2715-22
-
(2011)
Biomacromolecules
, vol.12
, pp. 2715-2722
-
-
Saik, J.E.1
Gould, D.J.2
Keswani, A.H.3
Dickinson, M.E.4
West, J.L.5
-
128
-
-
80054089846
-
Targeted lung cancer therapy using ephrinA1-loaded albumin microspheres
-
Lee HY, Mohammed KA, Peruvemba S, Goldberg EP, Nasreen N. 2011. Targeted lung cancer therapy using ephrinA1-loaded albumin microspheres. J. Pharm. Pharmacol. 63:1401-10
-
(2011)
J. Pharm. Pharmacol.
, vol.63
, pp. 1401-1410
-
-
Lee, H.Y.1
Mohammed, K.A.2
Peruvemba, S.3
Goldberg, E.P.4
Nasreen, N.5
-
129
-
-
80755189391
-
-
Nano Lett.
-
Lohmuller T, Triffo S, ODonoghue GP, Xu Q, Coyle MP, Groves JT. 2011. Supported membranes embedded with fixed arrays of gold nanoparticles. Nano Lett. 11:4912-18
-
(2011)
Supported Membranes Embedded with Fixed Arrays of Gold Nanoparticles
, vol.11
, pp. 4912-4918
-
-
Lohmuller, T.1
Triffo, S.2
Odonoghue, G.P.3
Xu, Q.4
Coyle, M.P.5
Groves, J.T.6
-
130
-
-
84905283658
-
Spatial control of membrane receptor function using ligand nanocalipers
-
Shaw A, Lundin V, Petrova E, F ord . os F, Benson E, et al. 2014. Spatial control of membrane receptor function using ligand nanocalipers. Nat. Methods 11:841-46
-
(2014)
Nat. Methods
, vol.11
, pp. 841-846
-
-
Shaw, A.1
Lundin, V.2
Petrova, E.3
Fordos, F.4
Benson, E.5
-
131
-
-
33646434790
-
Anti-EphA2 antibodies decrease EphA2 protein levels in murine CT26 colorectal and human MDA-231 breast tumors but do not inhibit tumor growth
-
Kiewlich D, Zhang J, Gross C, Xia W, Larsen B, et al. 2006. Anti-EphA2 antibodies decrease EphA2 protein levels in murine CT26 colorectal and human MDA-231 breast tumors but do not inhibit tumor growth. Neoplasia 8:18-30
-
(2006)
Neoplasia
, vol.8
, pp. 18-30
-
-
Kiewlich, D.1
Zhang, J.2
Gross, C.3
Xia, W.4
Larsen, B.5
-
132
-
-
10744228315
-
Differential EphA2 epitope display on normal versus malignant cells
-
Coffman KT, Hu M, Carles-Kinch K, Tice D, Donacki N, et al. 2003. Differential EphA2 epitope display on normal versus malignant cells. Cancer Res. 63:7907-12
-
(2003)
Cancer Res.
, vol.63
, pp. 7907-7912
-
-
Coffman, K.T.1
Hu, M.2
Carles-Kinch, K.3
Tice, D.4
Donacki, N.5
-
133
-
-
78650409745
-
Clinical and biological impact of EphA2 overexpression and angiogenesis in endometrial cancer
-
Merritt WM, Kamat AA, Hwang JY, Bottsford-Miller J, Lu C, et al. 2010. Clinical and biological impact of EphA2 overexpression and angiogenesis in endometrial cancer. Cancer Biol. Ther. 10:1306-14
-
(2010)
Cancer Biol. Ther.
, vol.10
, pp. 1306-1314
-
-
Merritt, W.M.1
Kamat, A.A.2
Hwang, J.Y.3
Bottsford-Miller, J.4
Lu, C.5
-
134
-
-
66449098768
-
Antibodydependent cell-mediated cytotoxicity effector-enhanced EphA2 agonist monoclonal antibody demonstrates potent activity against human tumors
-
Bruckheimer EM, Fazenbaker CA, Gallagher S, Mulgrew K, Fuhrmann S, et al. 2009. Antibodydependent cell-mediated cytotoxicity effector-enhanced EphA2 agonist monoclonal antibody demonstrates potent activity against human tumors. Neoplasia 11:509-17
-
(2009)
Neoplasia
, vol.11
, pp. 509-517
-
-
Bruckheimer, E.M.1
Fazenbaker, C.A.2
Gallagher, S.3
Mulgrew, K.4
Fuhrmann, S.5
-
135
-
-
77951757063
-
EphA2 targeted chemotherapy using an antibody drug conjugate in endometrial carcinoma
-
Lee JW, Stone RL, Lee SJ, Nam EJ, Roh JW, et al. 2010. EphA2 targeted chemotherapy using an antibody drug conjugate in endometrial carcinoma. Clin. Cancer Res. 16:2562-70
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 2562-2570
-
-
Lee, J.W.1
Stone, R.L.2
Lee, S.J.3
Nam, E.J.4
Roh, J.W.5
-
136
-
-
84861083859
-
Blocking ephrinB2 with highly specific antibodies inhibits angiogenesis, lymphangiogenesis, and tumor growth
-
Abengozar MA, de Frutos S, Ferreiro S, Soriano J, Perez-Martinez M, et al. 2012. Blocking ephrinB2 with highly specific antibodies inhibits angiogenesis, lymphangiogenesis, and tumor growth. Blood 119:4565-76
-
(2012)
Blood
, vol.119
, pp. 4565-4576
-
-
Abengozar, M.A.1
De Frutos, S.2
Ferreiro, S.3
Soriano, J.4
Perez-Martinez, M.5
-
137
-
-
77955484001
-
Converging evidence for efficacy from parallel EphB4-targeted approaches in ovarian carcinoma
-
Spannuth WA, Mangala LS, Stone RL, Carroll AR, Nishimura M, et al. 2010. Converging evidence for efficacy from parallel EphB4-targeted approaches in ovarian carcinoma. Mol. Cancer Ther. 9:2377-88
-
(2010)
Mol. Cancer Ther.
, vol.9
, pp. 2377-2388
-
-
Spannuth, W.A.1
Mangala, L.S.2
Stone, R.L.3
Carroll, A.R.4
Nishimura, M.5
-
138
-
-
84862486945
-
Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor
-
Lamberto I, Qin H, Noberini R, Premkumar L, Bourgin C, et al. 2012. Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor. Biochem. J. 445:47-56
-
(2012)
Biochem. J.
, vol.445
, pp. 47-56
-
-
Lamberto, I.1
Qin, H.2
Noberini, R.3
Premkumar, L.4
Bourgin, C.5
-
139
-
-
20344376236
-
EphB receptor-binding peptides identified by phage display enable design of an antagonist with ephrin-like affinity
-
Koolpe M, Burgess R, Dail M, Pasquale EB. 2005. EphB receptor-binding peptides identified by phage display enable design of an antagonist with ephrin-like affinity. J. Biol. Chem. 280:17301-11
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17301-17311
-
-
Koolpe, M.1
Burgess, R.2
Dail, M.3
Pasquale, E.B.4
-
140
-
-
84875147480
-
Design and synthesis of potent bivalent peptide agonists targeting the EphA2 receptor
-
Duggineni S, Mitra S, Lamberto I, Han X, Xu Y, et al. 2013. Design and synthesis of potent bivalent peptide agonists targeting the EphA2 receptor. ACS Med. Chem. Lett. 4:344-48
-
(2013)
ACS Med. Chem. Lett.
, vol.4
, pp. 344-348
-
-
Duggineni, S.1
Mitra, S.2
Lamberto, I.3
Han, X.4
Xu, Y.5
-
141
-
-
83355173217
-
PEGylation potentiates the effectiveness of an antagonistic peptide that targets the EphB4 receptor with nanomolar affinity
-
Noberini R, Mitra S, Salvucci O, Valencia F, Duggineni S, et al. 2011. PEGylation potentiates the effectiveness of an antagonistic peptide that targets the EphB4 receptor with nanomolar affinity. PLOS ONE 6:e28611
-
(2011)
Plos One
, vol.6
, pp. e28611
-
-
Noberini, R.1
Mitra, S.2
Salvucci, O.3
Valencia, F.4
Duggineni, S.5
-
142
-
-
79957918283
-
Peptide-conjugated polymeric micellar nanoparticles for Dual SPECT and optical imaging of EphB4 receptors in prostate cancer xenografts
-
Zhang R, Xiong C, Huang M, Zhou M, Huang Q, et al. 2011. Peptide-conjugated polymeric micellar nanoparticles for Dual SPECT and optical imaging of EphB4 receptors in prostate cancer xenografts. Biomaterials 32:5872-79
-
(2011)
Biomaterials
, vol.32
, pp. 5872-5879
-
-
Zhang, R.1
Xiong, C.2
Huang, M.3
Zhou, M.4
Huang, Q.5
-
143
-
-
84871946992
-
Targeted delivery of paclitaxel to EphA2-expressing cancer cells
-
Wang S, Noberini R, Stebbins JL, Das S, Zhang Z, et al. 2013. Targeted delivery of paclitaxel to EphA2-expressing cancer cells. Clin. Cancer Res. 19:128-37
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 128-137
-
-
Wang, S.1
Noberini, R.2
Stebbins, J.L.3
Das, S.4
Zhang, Z.5
-
144
-
-
77955252631
-
Structure-activity relationship analysis of peptides targeting the EphA2 receptor
-
Mitra S, Duggineni S, Koolpe M, Zhu X, Huang Z, Pasquale EB. 2010. Structure-activity relationship analysis of peptides targeting the EphA2 receptor. Biochemistry 49:6687-95
-
(2010)
Biochemistry
, vol.49
, pp. 6687-6695
-
-
Mitra, S.1
Duggineni, S.2
Koolpe, M.3
Zhu, X.4
Huang, Z.5
Pasquale, E.B.6
-
145
-
-
84863291820
-
Novel targeted system to deliver chemotherapeutic drugs to EphA2-expressing cancer cells
-
Wang S, Placzek WJ, Stebbins JL, Mitra S, Noberini R, et al. 2012. Novel targeted system to deliver chemotherapeutic drugs to EphA2-expressing cancer cells. J. Med. Chem. 55:2427-36
-
(2012)
J. Med. Chem.
, vol.55
, pp. 2427-2436
-
-
Wang, S.1
Placzek, W.J.2
Stebbins, J.L.3
Mitra, S.4
Noberini, R.5
-
146
-
-
84872687126
-
Design, synthesis and characterization of novel small molecular inhibitors of ephrin-B2 binding to EphB4
-
Duggineni S, Mitra S, Noberini R, Han X, Lin N, et al. 2013. Design, synthesis and characterization of novel small molecular inhibitors of ephrin-B2 binding to EphB4. Biochem. Pharmacol. 85:507-13
-
(2013)
Biochem. Pharmacol.
, vol.85
, pp. 507-513
-
-
Duggineni, S.1
Mitra, S.2
Noberini, R.3
Han, X.4
Lin, N.5
-
147
-
-
84872928524
-
HTS by NMR of combinatorial libraries: A fragment-based approach to ligand discovery
-
Wu B, Zhang Z, Noberini R, Barile E, Giulianotti M, et al. 2013. HTS by NMR of combinatorial libraries: A fragment-based approach to ligand discovery. Chem. Biol. 20:19-33
-
(2013)
Chem. Biol.
, vol.20
, pp. 19-33
-
-
Wu, B.1
Zhang, Z.2
Noberini, R.3
Barile, E.4
Giulianotti, M.5
-
148
-
-
84876273467
-
Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor
-
Incerti M, Tognolini M, Russo S, Pala D, Giorgio C, et al. 2013. Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor. J. Med. Chem. 56:2936-47
-
(2013)
J. Med. Chem.
, vol.56
, pp. 2936-2947
-
-
Incerti, M.1
Tognolini, M.2
Russo, S.3
Pala, D.4
Giorgio, C.5
-
149
-
-
84898753092
-
Crosstalk between EphA2 and BRaf/CRaf is a key determinant of response to dasatinib
-
Huang J, Hu W, Bottsford-Miller J, Liu T, Han HD, et al. 2014. Crosstalk between EphA2 and BRaf/CRaf is a key determinant of response to dasatinib. Clin. Cancer Res. 20:1846-55
-
(2014)
Clin. Cancer Res.
, vol.20
, pp. 1846-1855
-
-
Huang, J.1
Hu, W.2
Bottsford-Miller, J.3
Liu, T.4
Han, H.D.5
-
150
-
-
78149412006
-
The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis
-
Martiny-Baron G, Holzer P, Billy E, Schnell C, Brueggen J, et al. 2010. The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis. Angiogenesis 13:259-67
-
(2010)
Angiogenesis
, vol.13
, pp. 259-267
-
-
Martiny-Baron, G.1
Holzer, P.2
Billy, E.3
Schnell, C.4
Brueggen, J.5
-
151
-
-
77953029002
-
Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis
-
Wang Y, Nakayama M, Pitulescu ME, Schmidt TS, Bochenek ML, et al. 2010. Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis. Nature 465:483-86
-
(2010)
Nature
, vol.465
, pp. 483-486
-
-
Wang, Y.1
Nakayama, M.2
Pitulescu, M.E.3
Schmidt, T.S.4
Bochenek, M.L.5
-
152
-
-
84877092185
-
Enhancing chemotherapy response with sustained EphA2 silencing using multistage vector delivery
-
Shen H, Rodriguez-Aguayo C, Xu R, Gonzalez-Villasana V, Mai J, et al. 2013. Enhancing chemotherapy response with sustained EphA2 silencing using multistage vector delivery. Clin. Cancer Res. 19:1806-15
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 1806-1815
-
-
Shen, H.1
Rodriguez-Aguayo, C.2
Xu, R.3
Gonzalez-Villasana, V.4
Mai, J.5
-
153
-
-
68049144915
-
Dual targeting of EphA2 and FAK in ovarian carcinoma
-
Shahzad MM, Lu C, Lee JW, Stone RL, Mitra R, et al. 2009. Dual targeting of EphA2 and FAK in ovarian carcinoma. Cancer Biol. Ther. 8:1027-34
-
(2009)
Cancer Biol. Ther.
, vol.8
, pp. 1027-1034
-
-
Shahzad, M.M.1
Lu, C.2
Lee, J.W.3
Stone, R.L.4
Mitra, R.5
-
154
-
-
56449085913
-
A human antibody-drug conjugate targeting EphA2 inhibits tumor growth in vivo
-
Jackson D, Gooya J, Mao S, Kinneer K, Xu L, et al. 2008. A human antibody-drug conjugate targeting EphA2 inhibits tumor growth in vivo. Cancer Res. 68:9367-74
-
(2008)
Cancer Res.
, vol.68
, pp. 9367-9374
-
-
Jackson, D.1
Gooya, J.2
Mao, S.3
Kinneer, K.4
Xu, L.5
-
155
-
-
69949135318
-
EphA2 immunoconjugate as molecularly targeted chemotherapy for ovarian carcinoma
-
Lee JW, Han HD, Shahzad MM, Kim SW, Mangala LS, et al. 2009. EphA2 immunoconjugate as molecularly targeted chemotherapy for ovarian carcinoma. J. Natl. Cancer Inst. 101:1193-205
-
(2009)
J. Natl. Cancer Inst.
, vol.101
, pp. 1193-1205
-
-
Lee, J.W.1
Han, H.D.2
Shahzad, M.M.3
Kim, S.W.4
Mangala, L.S.5
-
156
-
-
36148975921
-
Quantitative radioimmunoPET imaging of EphA2 in tumor-bearing mice
-
Cai W, Ebrahimnejad A, Chen K, Cao Q, Li ZB, et al. 2007. Quantitative radioimmunoPET imaging of EphA2 in tumor-bearing mice. Eur. J. Nucl. Med. Mol. Imaging 34:2024-36
-
(2007)
Eur. J. Nucl. Med. Mol. Imaging
, vol.34
, pp. 2024-2036
-
-
Cai, W.1
Ebrahimnejad, A.2
Chen, K.3
Cao, Q.4
Li, Z.B.5
-
157
-
-
84872016241
-
EphA2 targeted doxorubicin stealth liposomes as a therapy system for choroidal neovascularization in rats
-
Wang JL, Liu YL, Li Y, Dai WB, Guo ZM, et al. 2012. EphA2 targeted doxorubicin stealth liposomes as a therapy system for choroidal neovascularization in rats. Investig. Ophthalmol. Vis. Sci. 53:7348-57
-
(2012)
Investig. Ophthalmol. Vis. Sci.
, vol.53
, pp. 7348-7357
-
-
Wang, J.L.1
Liu, Y.L.2
Li, Y.3
Dai, W.B.4
Guo, Z.M.5
-
158
-
-
76749164888
-
Chemosensitization of cancer cells by siRNA using targeted nanogel delivery
-
Dickerson EB, Blackburn WH, Smith MH, Kapa LB, Lyon LA, McDonald JF. 2010. Chemosensitization of cancer cells by siRNA using targeted nanogel delivery. BMC Cancer 10:10
-
(2010)
BMC Cancer
, vol.10
, pp. 10
-
-
Dickerson, E.B.1
Blackburn, W.H.2
Smith, M.H.3
Kapa, L.B.4
Lyon, L.A.5
McDonald, J.F.6
-
159
-
-
23044497596
-
Concurrent binding of anti-EphA3 antibody and ephrin-A5 amplifies EphA3 signaling and downstream responses: Potential as EphA3-specific tumor-targeting reagents
-
Vearing C, Lee FT, Wimmer-Kleikamp S, Spirkoska V, To C, et al. 2005. Concurrent binding of anti-EphA3 antibody and ephrin-A5 amplifies EphA3 signaling and downstream responses: potential as EphA3-specific tumor-targeting reagents. Cancer Res. 65:6745-54
-
(2005)
Cancer Res.
, vol.65
, pp. 6745-6754
-
-
Vearing, C.1
Lee, F.T.2
Wimmer-Kleikamp, S.3
Spirkoska, V.4
To, C.5
-
160
-
-
58149277085
-
EphrinA1-targeted nanoshells for photothermal ablation of prostate cancer cells
-
Gobin AM, Moon JJ, West JL. 2008. EphrinA1-targeted nanoshells for photothermal ablation of prostate cancer cells. Int. J. Nanomedicine 3:351-58
-
(2008)
Int. J. Nanomedicine
, vol.3
, pp. 351-358
-
-
Gobin, A.M.1
Moon, J.J.2
West, J.L.3
-
161
-
-
10744222441
-
EphB2 as a therapeutic antibody drug target for the treatment of colorectal cancer
-
Mao W, Luis E, Ross S, Silva J, Tan C, et al. 2004. EphB2 as a therapeutic antibody drug target for the treatment of colorectal cancer. Cancer Res. 64:781-88
-
(2004)
Cancer Res.
, vol.64
, pp. 781-788
-
-
Mao, W.1
Luis, E.2
Ross, S.3
Silva, J.4
Tan, C.5
-
162
-
-
84889255926
-
EphB4-targeted imaging with antibody h131, h131- F(ab-)2 and h131-Fab
-
Li D, Liu S, Liu R, Zhou Y, Park R, et al. 2013. EphB4-targeted imaging with antibody h131, h131- F(ab-)2 and h131-Fab. Mol. Pharm. 10:4527-33
-
(2013)
Mol. Pharm.
, vol.10
, pp. 4527-4533
-
-
Li, D.1
Liu, S.2
Liu, R.3
Zhou, Y.4
Park, R.5
-
163
-
-
84879918367
-
PET imaging of colorectal and breast cancer by targeting EphB4 receptor with 64Cu-labeled hAb47 and hAb131 antibodies
-
Liu S, Li D, Park R, Liu R, Xia Z, et al. 2013. PET imaging of colorectal and breast cancer by targeting EphB4 receptor with 64Cu-labeled hAb47 and hAb131 antibodies. J. Nucl. Med. 54:1094-100
-
(2013)
J. Nucl. Med.
, vol.54
, pp. 1094-1100
-
-
Liu, S.1
Li, D.2
Park, R.3
Liu, R.4
Xia, Z.5
-
164
-
-
84866427416
-
Effective photothermal chemotherapy using doxorubicin-loaded gold nanospheres that target EphB4 receptors in tumors
-
You J, Zhang R, Xiong C, Zhong M, Melancon M, et al. 2012. Effective photothermal chemotherapy using doxorubicin-loaded gold nanospheres that target EphB4 receptors in tumors. Cancer Res. 72:4777-86
-
(2012)
Cancer Res.
, vol.72
, pp. 4777-4786
-
-
You, J.1
Zhang, R.2
Xiong, C.3
Zhong, M.4
Melancon, M.5
-
165
-
-
84895077478
-
Dual-modality micro-positron emission tomography/computed tomography and near-infrared fluorescence imaging of EphB4 in orthotopic glioblastoma xenograft models
-
Huang M, Xiong C, Lu W, Zhang R, Zhou M, et al. 2014. Dual-modality micro-positron emission tomography/computed tomography and near-infrared fluorescence imaging of EphB4 in orthotopic glioblastoma xenograft models. Mol. Imaging Biol. 16:74-84
-
(2014)
Mol. Imaging Biol.
, vol.16
, pp. 74-84
-
-
Huang, M.1
Xiong, C.2
Lu, W.3
Zhang, R.4
Zhou, M.5
-
166
-
-
84875635844
-
Specific tumor delivery of paclitaxel using glycolipidlike polymer micelles containing gold nanospheres
-
You J, Wang Z, Du Y, Yuan H, Zhang P, et al. 2013. Specific tumor delivery of paclitaxel using glycolipidlike polymer micelles containing gold nanospheres. Biomaterials 34:4510-19
-
(2013)
Biomaterials
, vol.34
, pp. 4510-4519
-
-
You, J.1
Wang, Z.2
Du, Y.3
Yuan, H.4
Zhang, P.5
-
167
-
-
84875215925
-
T cells redirected to EphA2 for the immunotherapy of glioblastoma
-
Chow KK, Naik S, Kakarla S, Brawley VS, Shaffer DR, et al. 2013. T cells redirected to EphA2 for the immunotherapy of glioblastoma. Mol. Ther. 21:629-37
-
(2013)
Mol. Ther.
, vol.21
, pp. 629-637
-
-
Chow, K.K.1
Naik, S.2
Kakarla, S.3
Brawley, V.S.4
Shaffer, D.R.5
-
168
-
-
34248545438
-
Selective targeting and potent control of tumor growth using an EphA2/CD3-bispecific single-chain antibody construct
-
Hammond SA, Lutterbuese R, Roff S, Lutterbuese P, Schlereth B, et al. 2007. Selective targeting and potent control of tumor growth using an EphA2/CD3-bispecific single-chain antibody construct. Cancer Res. 67:3927-35
-
(2007)
Cancer Res.
, vol.67
, pp. 3927-3935
-
-
Hammond, S.A.1
Lutterbuese, R.2
Roff, S.3
Lutterbuese, P.4
Schlereth, B.5
-
169
-
-
84873084305
-
Phase 1, open-label study of MEDI-547 in patients with relapsed or refractory solid tumors
-
Annunziata CM, Kohn EC, LoRusso P, Houston ND, Coleman RL, et al. 2013. Phase 1, open-label study of MEDI-547 in patients with relapsed or refractory solid tumors. Investig. New Drugs 31:77-84
-
(2013)
Investig. New Drugs
, vol.31
, pp. 77-84
-
-
Annunziata, C.M.1
Kohn, E.C.2
Lorusso, P.3
Houston, N.D.4
Coleman, R.L.5
-
170
-
-
84899635533
-
ADAM12-cleaved ephrin-A1 contributes to lung metastasis
-
Ieguchi K, Tomita T, Omori T, Komatsu A, Deguchi A, et al. 2014. ADAM12-cleaved ephrin-A1 contributes to lung metastasis. Oncogene 33:2179-90
-
(2014)
Oncogene
, vol.33
, pp. 2179-2190
-
-
Ieguchi, K.1
Tomita, T.2
Omori, T.3
Komatsu, A.4
Deguchi, A.5
-
171
-
-
84920783412
-
Activation of membranebound proteins and receptor systems: A link between tissue kallikrein and the KLK-related peptidases
-
Dong Y, Harrington BS, Adams MN, Wortmann A, Stephenson SA, et al. 2014. Activation of membranebound proteins and receptor systems: A link between tissue kallikrein and the KLK-related peptidases. Biol. Chem. 395:977-90
-
(2014)
Biol. Chem.
, vol.395
, pp. 977-990
-
-
Dong, Y.1
Harrington, B.S.2
Adams, M.N.3
Wortmann, A.4
Stephenson, S.A.5
-
172
-
-
84919902944
-
EphrinB2 affects apical constriction in Xenopus embryos and is regulated by ADAM10 and flotillin-1
-
Ji YJ, Hwang YS, Mood K, Cho HJ, Lee HS, et al. 2014. EphrinB2 affects apical constriction in Xenopus embryos and is regulated by ADAM10 and flotillin-1. Nat. Commun. 5:3516
-
(2014)
Nat. Commun.
, vol.5
, pp. 3516
-
-
Ji, Y.J.1
Hwang, Y.S.2
Mood, K.3
Cho, H.J.4
Lee, H.S.5
|